Chronic Hippocampal Expression of Notch Intracellular Domain Induces Vascular Thickening, Reduces Glucose Availability, and Exacerbates Spatial Memory Deficits in a Rat Model of Early Alzheimer

Hippocampal CA1 activity correlated with the distance to the goal and navigation performance

(2017) Hugo J. Spiers et al.   HIPPOCAMPUS

Early Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer’s Disease

(2017) Miren Ettcheto et al.   MOLECULAR NEUROBIOLOGY

Hippocampal Proteomic Analysis Reveals Distinct Pathway Deregulation Profiles at Early and Late Stages in a Rat Model of Alzheimer’s-Like Amyloid Pathology

(2017) Sonia Do Carmo et al.   MOLECULAR NEUROBIOLOGY

Dynamic Nature of presenilin1/γ-Secretase: Implication for Alzheimer’s Disease Pathogenesis

(2017) Katarzyna Marta Zoltowska et al.   MOLECULAR NEUROBIOLOGY

A Novel Transgenic Rat Model with a Full Alzheimer's-Like Amyloid Pathology Displays Pre-Plaque Intracellular Amyloid-β-Associated Cognitive Impairment

(2017) Wanda Carolina Leon et al.   JOURNAL OF ALZHEIMERS DISEASE

Intraneuronal Amyloid Beta Accumulation Disrupts Hippocampal CRTC1-Dependent Gene Expression and Cognitive Function in a Rat Model of Alzheimer Disease

(2016) Edward N. Wilson et al.   CEREBRAL CORTEX

Synaptosomal bioenergetic defects are associated with cognitive impairment in a transgenic rat model of early Alzheimer's disease

(2016) Pamela V Martino Adami et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Glucose Transporters at the Blood-Brain Barrier: Function, Regulation and Gateways for Drug Delivery

(2016) Simon G. Patching   MOLECULAR NEUROBIOLOGY

Notch1 hallmarks fibrillary depositions in sporadic Alzheimer’s disease

(2016) Emanuele Brai et al.   Acta Neuropathologica Communications

Notch Intracellular Domain (NICD) Suppresses Long-Term Memory Formation in Adult Drosophila Flies

(2015) Jiabin Zhang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The Notch intracellular domain represses CRE-dependent transcription

(2015) Rania Hallaq et al.   CELLULAR SIGNALLING

Dissecting the Contribution of Vascular Alterations and Aging to Alzheimer’s Disease

(2015) Cátia Janota et al.   MOLECULAR NEUROBIOLOGY

The Essential Role of Soluble Aβ Oligomers in Alzheimer’s Disease

(2015) Zi-Xuan Wang et al.   MOLECULAR NEUROBIOLOGY

Production, purification and titration of a lentivirus-based vector for gene delivery purposes

(2014) Masoud Nasri et al.   CYTOTECHNOLOGY

MicroPET imaging and transgenic models: a blueprint for Alzheimer's disease clinical research

(2014) Eduardo R. Zimmer et al.   TRENDS IN NEUROSCIENCES

Longitudinal analysis of the behavioral phenotype in a novel transgenic rat model of early stages of Alzheimer's disease

(2014) Pablo Galeano et al.   Frontiers in Behavioral Neuroscience

Intracellular Aβ pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: a multidimensional study

(2014) M Florencia Iulita et al.   Acta Neuropathologica Communications

Modeling Alzheimer’s disease in transgenic rats

(2013) Sonia Do Carmo et al.   Molecular Neurodegeneration

Notch-1 Signaling Regulates Microglia Activation via NF-κB Pathway after Hypoxic Exposure In Vivo and In Vitro

(2013) Linli Yao et al.   PLoS One

HMDB 3.0—The Human Metabolome Database in 2013

(2012) David S. Wishart et al.   NUCLEIC ACIDS RESEARCH

Notch signaling proteins HES-1 and Hey-1 bind to insulin degrading enzyme (IDE) proximal promoter and repress its transcription and activity: Implications for cellular Aβ metabolism

(2011) María C. Leal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Neurovascular function in Alzheimer's disease patients and experimental models

(2011) Nektaria Nicolakakis et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Not(ch) just development: Notch signalling in the adult brain

(2011) Jessica L. Ables et al.   NATURE REVIEWS NEUROSCIENCE

Cerebral amyloid angiopathy: pathogenetic mechanisms and link to dense amyloid plaques

(2010) S. Kumar-Singh   GENES BRAIN AND BEHAVIOR

Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease

(2010) Dimitrios Kapogiannis et al.   LANCET NEUROLOGY

Hippocampal long-term depression is required for the consolidation of spatial memory

(2010) Y. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch-1 signalling is activated in brain arteriovenous malformations in humans

(2009) Q. ZhuGe et al.   BRAIN

Notch Signaling: The Core Pathway and Its Posttranslational Regulation

(2009) Mark E. Fortini   DEVELOPMENTAL CELL

Sustained Expression of α1-Antitrypsin after Transplantation of Manipulated Hematopoietic Stem Cells

(2008) Andrew A. Wilson et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Notch1 Signaling in Pyramidal Neurons Regulates Synaptic Connectivity and Experience-Dependent Modifications of Acuity in the Visual Cortex

(2008) M. Dahlhaus et al.   JOURNAL OF NEUROSCIENCE

HMDB: a knowledgebase for the human metabolome

(2008) D. S. Wishart et al.   NUCLEIC ACIDS RESEARCH

Altered morphology and 3D architecture of brain vasculature in a mouse model for Alzheimer's disease

(2008) E. P. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA