Early Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer’s Disease

Dysregulation of Histone Acetylation in the APP/PS1 Mouse Model of Alzheimer's Disease

(2017) Yitshak I. Francis et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuroinflammation in Alzheimer's disease: Current evidence and future directions

(2016) Valeria Calsolaro et al.   Alzheimers & Dementia

Adolescent exposure to MDMA induces dopaminergic toxicity in substantia nigra and potentiates the amyloid plaque deposition in the striatum of APPswe/PS1dE9 mice

(2016) Sonia Abad et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Insulin Resistance and Neurodegeneration: Progress Towards the Development of New Therapeutics for Alzheimer’s Disease

(2016) Suzanne M. de la Monte   DRUGS

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Evaluation of Neuropathological Effects of a High-Fat Diet in a Presymptomatic Alzheimer’s Disease Stage in APP/PS1 Mice

(2016) Miren Ettcheto et al.   JOURNAL OF ALZHEIMERS DISEASE

Current and future treatment of amyloid diseases

(2016) M. Ankarcrona et al.   JOURNAL OF INTERNAL MEDICINE

Defeating Alzheimer's disease and other dementias: a priority for European science and society

(2016) Bengt Winblad et al.   LANCET NEUROLOGY

Reduced pCREB in Alzheimer’s disease prefrontal cortex is reflected in peripheral blood mononuclear cells

(2016) N Bartolotti et al.   MOLECULAR PSYCHIATRY

Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer’s disease

(2016) Riqiang Yan et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Analyzing dendritic spine pathology in Alzheimer’s disease: problems and opportunities

(2015) Mario M. Dorostkar et al.   ACTA NEUROPATHOLOGICA

Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis

(2015) Kirsten L. Viola et al.   ACTA NEUROPATHOLOGICA

Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling

(2015) Samia Habbas et al.   CELL

Alzheimer’s Disease: Lessons Learned from Amyloidocentric Clinical Trials

(2015) Andreas Soejitno et al.   CNS DRUGS

Non-Steroidal Anti-Inflammatory Drugs as a Treatment for Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Treatment Effect

(2015) Marina Miguel-Álvarez et al.   DRUGS & AGING

Rodent models for Alzheimer’s disease drug discovery

(2015) Daniela Puzzo et al.   Expert Opinion on Drug Discovery

ADAM10 and BACE1 are localized to synaptic vesicles

(2015) Jolanta L. Lundgren et al.   JOURNAL OF NEUROCHEMISTRY

Neuroinflammatory Signals in Alzheimer Disease and APP/PS1 Transgenic Mice

(2015) Irene López-González et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Adaptive Plasticity in the Hippocampus of Young Mice Intermittently Exposed to MDMA Could Be the Origin of Memory Deficits

(2015) S. Abad et al.   MOLECULAR NEUROBIOLOGY

Synaptic Therapy in Alzheimer’s Disease: A CREB-centric Approach

(2015) Andrew F. Teich et al.   Neurotherapeutics

Aberrant insulin signaling in Alzheimer's disease: current knowledge

(2015) Gaurav Bedse et al.   Frontiers in Neuroscience

Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease

(2014) Sergio T. Ferreira et al.   Alzheimers & Dementia

How does brain insulin resistance develop in Alzheimer's disease?

(2014) Fernanda G. De Felice et al.   Alzheimers & Dementia

Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease

(2014) Ignacio Pedrós et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Alterations in Immune Cells and Mediators in the Brain: It's Not Always Neuroinflammation!

(2014) Myka L. Estes et al.   BRAIN PATHOLOGY

Advances in the therapy of Alzheimer’s disease: targeting amyloid beta and tau and perspectives for the future

(2014) Harald Hampel et al.   Expert Review of Neurotherapeutics

Transition from an M1 to a mixed neuroinflammatory phenotype increases amyloid deposition in APP/PS1 transgenic mice

(2014) Erica M Weekman et al.   Journal of Neuroinflammation

Potential for primary prevention of Alzheimer's disease: an analysis of population-based data

(2014) Sam Norton et al.   LANCET NEUROLOGY

The Alzheimer’s β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques

(2013) Patty C. Kandalepas et al.   ACTA NEUROPATHOLOGICA

Therapeutics of Alzheimer's disease: Past, present and future

(2013) R. Anand et al.   NEUROPHARMACOLOGY

Genetic mouse models of brain ageing and Alzheimer's disease

(2013) Andras Bilkei-Gorzo   PHARMACOLOGY & THERAPEUTICS

Early memory deficits precede plaque deposition in APPswe/PS1dE9 mice: Involvement of oxidative stress and cholinergic dysfunction

(2012) Wei Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Alzheimer's  -Secretase (BACE1) Regulates the cAMP/PKA/CREB Pathway Independently of  -Amyloid

(2012) Y. Chen et al.   JOURNAL OF NEUROSCIENCE

RETRACTED: Multiple inflammatory pathways are involved in the development and progression of cognitive deficits in APPswe/PS1dE9 mice

(2012) Wei Zhang et al.   NEUROBIOLOGY OF AGING

The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB

(2012) Eric R Kandel   Molecular Brain

Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease

(2011) Wei Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

Hippocampal Focal Knockout of CBP Affects Specific Histone Modifications, Long-Term Potentiation and Long-Term Memory

(2011) Ruth M Barrett et al.   NEUROPSYCHOPHARMACOLOGY

Anti-TNF-α reduces amyloid plaques and tau phosphorylation and induces CD11c-positive dendritic-like cell in the APP/PS1 transgenic mouse brains

(2010) Jian-Quan Shi et al.   BRAIN RESEARCH

CREB: a multifaceted regulator of neuronal plasticity and protection

(2010) Kensuke Sakamoto et al.   JOURNAL OF NEUROCHEMISTRY

CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease

(2010) A. Caccamo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of NMDA receptor Ca2+signalling and synaptic plasticity

(2009) C. Geoffrey Lau et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Amyloid Deposition and Inflammation in APPswe/PS1dE9 Mouse Model of Alzheimers Disease

(2009) Lingfei Ruan et al.   Current Alzheimer Research

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

(2009) Fiona E. McAlpine et al.   NEUROBIOLOGY OF DISEASE

Chronic Neuron-Specific Tumor Necrosis Factor-Alpha Expression Enhances the Local Inflammatory Environment Ultimately Leading to Neuronal Death in 3xTg-AD Mice

(2008) Michelle C. Janelsins et al.   AMERICAN JOURNAL OF PATHOLOGY

BACE1 gene deletion: Impact on behavioral function in a model of Alzheimer's disease

(2007) Dione Kobayashi et al.   NEUROBIOLOGY OF AGING