Notch1 hallmarks fibrillary depositions in sporadic Alzheimer’s disease

Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer’s disease

(2015) Yang Xiang et al.   ACTA NEUROPATHOLOGICA

Notch in memories: Points to remember

(2015) Swananda Marathe et al.   HIPPOCAMPUS

The emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease

(2015) Laura J. Blair et al.   JOURNAL OF NEUROCHEMISTRY

Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease

(2014) Sergio T. Ferreira et al.   Alzheimers & Dementia

How does brain insulin resistance develop in Alzheimer's disease?

(2014) Fernanda G. De Felice et al.   Alzheimers & Dementia

Lessons from a Failed γ-Secretase Alzheimer Trial

(2014) Bart De Strooper   CELL

Notch1 activity in the olfactory bulb is odour-dependent and contributes to olfactory behaviour

(2014) Emanuele Brai et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Single App knock-in mouse models of Alzheimer's disease

(2014) Takashi Saito et al.   NATURE NEUROSCIENCE

Notch signaling in the brain: In good and bad times

(2013) Lavinia Alberi et al.   AGEING RESEARCH REVIEWS

Hepatic Notch Signaling Correlates With Insulin Resistance and Nonalcoholic Fatty Liver Disease

(2013) L. Valenti et al.   DIABETES

Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast

(2013) Alessandra Rustighi et al.   EMBO Molecular Medicine

CSF Presenilin-1 complexes are increased in Alzheimer’s disease

(2013) María-Salud García-Ayllón et al.   Acta Neuropathologica Communications

Extrusion of misfolded and aggregated proteins - a protective strategy of aging neurons?

(2012) Jana Doehner et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice

(2012) Dimitrije Krstic et al.   Journal of Neuroinflammation

The Notch signalling system: recent insights into the complexity of a conserved pathway

(2012) K. G. Guruharsha et al.   NATURE REVIEWS GENETICS

Quintessential Risk Factors: Their Role in Promoting Cognitive Dysfunction and Alzheimer’s Disease

(2012) Mak Adam Daulatzai   NEUROCHEMICAL RESEARCH

Trans-Synaptic Spread of Tau Pathology In Vivo

(2012) Li Liu et al.   PLoS One

Extracting  -amyloid from Alzheimer's disease

(2012) D. R. Dries et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch signaling proteins HES-1 and Hey-1 bind to insulin degrading enzyme (IDE) proximal promoter and repress its transcription and activity: Implications for cellular Aβ metabolism

(2011) María C. Leal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mouse models of Alzheimer's disease

(2011) Alicia M. Hall et al.   BRAIN RESEARCH BULLETIN

Noncanonical notch function in motor axon guidance is mediated by Rac GTPase and the GEF1 domain of trio

(2011) Jeong K. Song et al.   DEVELOPMENTAL DYNAMICS

Circulating Extracellular Proteasome in the Cerebrospinal Fluid: A Study on Concentration and Proteolytic Activity

(2011) Oliver Mueller et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Activity-Induced Notch Signaling in Neurons Requires Arc/Arg3.1 and Is Essential for Synaptic Plasticity in Hippocampal Networks

(2011) Lavinia Alberi et al.   NEURON

Notch Activation Enhances the Microglia-Mediated Inflammatory Response Associated With Focal Cerebral Ischemia

(2011) Zelan Wei et al.   STROKE

The secretases: enzymes with therapeutic potential in Alzheimer disease

(2010) Bart De Strooper et al.   Nature Reviews Neurology

Establishing the Proteome of Normal Human Cerebrospinal Fluid

(2010) Steven E. Schutzer et al.   PLoS One

Neonatal Stroke in Mice Causes Long-Term Changes in Neuronal Notch-2 Expression That May Contribute to Prolonged Injury

(2010) L. Alberi et al.   STROKE

Genome-wide Association Study Implicates a Chromosome 12 Risk Locus for Late-Onset Alzheimer Disease

(2009) Gary W. Beecham et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Alzheimer’s disease and Notch signaling

(2009) Ha-Na Woo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Clearance of Amyloid-β Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimers Disease

(2009) R. Deane et al.   CNS & Neurological Disorders-Drug Targets

Jagged1 regulates the activation of astrocytes via modulation of NFκB and JAK/STAT/SOCS pathways

(2009) Eleonora Morga et al.   GLIA

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer

(2009) Alessandra Rustighi et al.   NATURE CELL BIOLOGY

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Extracellular, circulating proteasomes and ubiquitin — Incidence and relevance

(2008) Stephan U. Sixt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A genome-wide association study for late-onset Alzheimer's disease using DNA pooling

(2008) Richard Abraham et al.   BMC Medical Genomics

Amyloid-Degrading Enzymes as Therapeutic Targets in Alzheimers Disease

(2008) Natalia Nalivaeva et al.   Current Alzheimer Research

Expression of Notch-1 receptor and its ligands Jagged-1 and Delta-1 in amoeboid microglia in postnatal rat brain and murine BV-2 cells

(2008) Qiong Cao et al.   GLIA

Microtubule stabilizing effect of notch activation in primary cortical neurons

(2008) G. Ferrari-Toninelli et al.   NEUROSCIENCE

Reciprocal regulation of Notch and PI3K/Akt signalling in T-ALL cells In Vitro

(2007) Elisabetta Calzavara et al.   JOURNAL OF CELLULAR BIOCHEMISTRY