Marine Carbohydrate-Based Compounds with Medicinal Properties

Structure and anticancer activity of native and modified polysaccharides from brown alga Dictyota dichotoma

(2018) Roza V. Usoltseva et al.   CARBOHYDRATE POLYMERS

A novel structural fucosylated chondroitin sulfate from Holothuria Mexicana and its effects on growth factors binding and anticoagulation

(2018) Qinying Li et al.   CARBOHYDRATE POLYMERS

Structural comparison, antioxidant and anti-inflammatory properties of fucosylated chondroitin sulfate of three edible sea cucumbers

(2018) Jiaojiao Mou et al.   CARBOHYDRATE POLYMERS

The mechanisms of sulfated polysaccharide drug of propylene glycol alginate sodium sulfate (PSS) on bleeding side effect

(2018) Yi-Ting Xue et al.   CARBOHYDRATE POLYMERS

Structural characteristics and anticancer activity in vitro of fucoidan from brown alga Padina boryana

(2018) Roza V. Usoltseva et al.   CARBOHYDRATE POLYMERS

Separation, purification, structures and anticoagulant activities of fucosylated chondroitin sulfates from Holothuria scabra

(2018) Liu Yang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Antifungal, antioxidant and cytotoxic activities of chitosan nanoparticles and its use as an edible coating on vegetables

(2018) K. Divya et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Lectin obtained from the red seaweed Bryothamnion triquetrum : Secondary structure and anti-inflammatory activity in mice

(2018) Thais Pontes Carvalho Fontenelle et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Chitin and chitosan preparation from shrimp shells Penaeus monodon and its human ovarian cancer cell line, PA-1

(2018) Haripriya Srinivasan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Development of an enteric nanoparticle of marine sulfated polysaccharide propylene glycol alginate sodium sulfate for oral administration: formulation design, pharmacokinetics and efficacy

(2018) Pengli Li et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Antimicrobial properties of chitosan nanoparticles: Mode of action and factors affecting activity

(2017) K. Divya et al.   FIBERS AND POLYMERS

Phytochemical constituents of fucoidan (Padina tetrastromatica) and its assisted AgNPs for enhanced antibacterial activity

(2017) S. Rajeshkumar   IET Nanobiotechnology

Influence of carrageenan on cytokine production and cellular activity of mouse peritoneal macrophages and its effect on experimental endotoxemia

(2017) A. A. Kalitnik et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Cerebrosides from Sea Cucumber Protect Against Oxidative Stress in SAMP8 Mice and PC12 Cells

(2017) Hongxia Che et al.   JOURNAL OF MEDICINAL FOOD

Propylene Glycol Alginate Sodium Sulfate Alleviates Cerulein‐Induced Acute Pancreatitis by Modulating the MEK/ERK Pathway in Mice

(2017) Hui Zhang et al.   Marine Drugs

The Inhibitory Activity of Luzonicosides from the Starfish Echinaster luzonicus against Human Melanoma Cells

(2017) Olesya Malyarenko et al.   Marine Drugs

Sea Cucumber Glycosides: Chemical Structures, Producing Species and Important Biological Properties

(2017) Muhammad Abdul Mojid Mondol et al.   Marine Drugs

A Novel High-Mannose Specific Lectin from the Green Alga Halimeda renschii Exhibits a Potent Anti-Influenza Virus Activity through High-Affinity Binding to the Viral Hemagglutinin

(2017) Jinmin Mu et al.   Marine Drugs

Characterization and Potential Antitumor Activity of Polysaccharide from Gracilariopsis lemaneiformis

(2017) Yani Kang et al.   Marine Drugs

Litopenaeus vannamei hemocyanin exhibits antitumor activity in S180 mouse model in vivo

(2017) Shangjie Liu et al.   PLoS One

The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity

(2017) Shizan Xu et al.   Scientific Reports

Neuroprotective Effects of Sulphated Agaran from Marine AlgaGracilaria corneain Rat 6-Hydroxydopamine Parkinson's Disease Model: Behavioural, Neurochemical and Transcriptional Alterations

(2016) Ricardo Basto Souza et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Cowpea resistance induced against Fusarium oxysporum f. sp. tracheiphilum by crustaceous chitosan and by biomass and chitosan obtained from Cunninghamella elegans

(2016) Lúcia Raquel Ramos Berger et al.   BIOLOGICAL CONTROL

Carrageenan delays cell cycle progression in human cancer cells in vitro demonstrated by FUCCI imaging

(2016) Eka Sunarwidhi Prasedya et al.   BMC Complementary and Alternative Medicine

Three dimensional alginate-fucoidan composite hydrogel augments the chondrogenic differentiation of mesenchymal stromal cells

(2016) Puvanan Karunanithi et al.   CARBOHYDRATE POLYMERS

Antimicrobial Sulfated Glycans: Structure and Function

(2016) Vitor Pomin   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Anticoagulant and antithrombotic activities of low-molecular-weight propylene glycol alginate sodium sulfate (PSS)

(2016) Meng Xin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Effects of carrageenan on cell permeability, cytotoxicity, and cytokine gene expression in human intestinal and hepatic cell lines

(2016) James M. McKim et al.   FOOD AND CHEMICAL TOXICOLOGY

Molecular Characterization and Anti-inflammatory Activity of Galactosylglycerides and Galactosylceramides from the Microalga Isochrysis galbana

(2016) Carolina de los Reyes et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

In vitro anticancer activity of the laminarans from Far Eastern brown seaweeds and their sulfated derivatives

(2016) Olesya S. Malyarenko et al.   JOURNAL OF APPLIED PHYCOLOGY

A Multivalent Marine Lectin from Crenomytilus grayanus Possesses Anti-cancer Activity through Recognizing Globotriose Gb3

(2016) Jiahn-Haur Liao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pharmacokinetics in Mouse and Comparative Effects of Frondosides in Pancreatic Cancer

(2016) Jasem Al Shemaili et al.   Marine Drugs

In Vivo Anti-Cancer Mechanism of Low-Molecular-Weight Fucosylated Chondroitin Sulfate (LFCS) from Sea Cucumber Cucumaria frondosa

(2016) Xiaoxiao Liu et al.   MOLECULES

Antinociceptive and Anti-inflammatory Activities of the Lectin from Marine Red Alga Solieria filiformis

(2016) Ticiana Abreu et al.   PLANTA MEDICA

An Ocean of Discovery: Biodiversity Beyond the Census of Marine Life

(2016) Paul Snelgrove   PLANTA MEDICA

Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases—Not Glycolipid Processing Enzymes

(2016) Andrew C. Sayce et al.   PLoS Neglected Tropical Diseases

Floridoside production by the red microalga Galdieria sulphuraria under different conditions of growth and osmotic stress

(2016) Marta Martinez-Garcia et al.   AMB Express

The cancer glycome: Carbohydrates as mediators of metastasis

(2015) Siobhan V. Glavey et al.   BLOOD REVIEWS

Anti-HIV activity of fucoidans from three brown seaweed species

(2015) Thanh Thi Thu Thuy et al.   CARBOHYDRATE POLYMERS

Effect of sodium-alginate and laminaran on Salmonella Typhimurium infection in human enterocyte-like HT-29-Luc cells and BALB/c mice

(2015) Takashi Kuda et al.   CARBOHYDRATE POLYMERS

Sulfated glycans in inflammation

(2015) Vitor H. Pomin   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structural characterization and antioxidant activities of κ-carrageenan oligosaccharides degraded by different methods

(2015) Yujiao Sun et al.   FOOD CHEMISTRY

Antioxidant Activity of Alginic Acid in Minced Pork Meat

(2015) Yasushi Endo et al.   FOOD SCIENCE AND TECHNOLOGY RESEARCH

Structure and biological activity of a fucosylated chondroitin sulfate from the sea cucumberCucumaria japonica

(2015) Nadezhda E Ustyuzhanina et al.   GLYCOBIOLOGY

Sulfated glycans in sea urchin fertilization

(2015) Vitor H. Pomin   GLYCOCONJUGATE JOURNAL

The Effects of Marine Carbohydrates and Glycosylated Compounds on Human Health

(2015) Hee-Kyoung Kang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapies from Fucoidan: An Update

(2015) Janet Fitton et al.   Marine Drugs

Anticancer Activity of Sea Cucumber Triterpene Glycosides

(2015) Dmitry Aminin et al.   Marine Drugs

λ-Carrageenan P32 Is a Potent Inhibitor of Rabies Virus Infection

(2015) Zhaochen Luo et al.   PLoS One

Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1

(2015) Jésica V. Diogo et al.   RESEARCH IN VETERINARY SCIENCE

Antitumor and Adjuvant Activity of λ-carrageenan by Stimulating Immune Response in Cancer Immunotherapy

(2015) Min Luo et al.   Scientific Reports

Antiviral Potential of Algae Polysaccharides Isolated from Marine Sources: A Review

(2015) Azin Ahmadi et al.   Biomed Research International

Cholesterol, sphingolipids, and glycolipids: What do we know about their role in raft-like membranes?

(2014) Tomasz Róg et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Effects of dietary fucoidan on the blood constituents, anti-oxidation and innate immunity of juvenile yellow catfish (Pelteobagrus fulvidraco)

(2014) Qing Yang et al.   FISH & SHELLFISH IMMUNOLOGY

Antitumor properties of a new non-anticoagulant heparin analog from the mollusk Nodipecten nodosus: Effect on P-selectin, heparanase, metastasis and cellular recruitment

(2014) Angélica Maciel Gomes et al.   GLYCOBIOLOGY

Extraction, structure and biofunctional activities of laminarin from brown algae

(2014) Shekhar U. Kadam et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY

Fucosylated Chondroitin Sulfates from the Body Wall of the Sea Cucumber Holothuria forskali

(2014) Charalampos G. Panagos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chitosan extracted from mud crab (Scylla olivicea) shells: physicochemical and antioxidant properties

(2014) N.M. Sarbon et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Cytotoxic and Apoptosis-Inducing Activity of Triterpene Glycosides from Holothuria scabra and Cucumaria frondosa against HepG2 Cells

(2014) Juanjuan Wang et al.   Marine Drugs

Variegatusides: New Non-Sulphated Triterpene Glycosides from the Sea Cucumber Stichopus variegates Semper

(2014) Xiao-Hua Wang et al.   Marine Drugs

Total Synthesis and Structure-Activity Relationship of Glycoglycerolipids from Marine Organisms

(2014) Jun Zhang et al.   Marine Drugs

Holothurian Fucosylated Chondroitin Sulfate

(2014) Vitor Pomin   Marine Drugs

Algal sulfated carrageenan inhibits proliferation of MDA-MB-231 cells via apoptosis regulatory genes

(2014) HOSSAM MURAD et al.   Molecular Medicine Reports

Polar lipids from the marine macroalga Palmaria palmata inhibit lipopolysaccharide-induced nitric oxide production in RAW264.7 macrophage cells

(2014) Arjun H. Banskota et al.   PHYTOCHEMISTRY

Marine medicinal glycomics

(2014) Vitor H. Pomin   Frontiers in Cellular and Infection Microbiology

Glycolipids from seaweeds and their potential biotechnological applications

(2014) Erwan Plouguerné et al.   Frontiers in Cellular and Infection Microbiology

Relationships between chemical structures and functions of triterpene glycosides isolated from sea cucumbers

(2014) Joo-In Park et al.   Frontiers in Chemistry

Antioxidant activity potential of gamma irradiated carrageenan

(2013) Lucille V. Abad et al.   APPLIED RADIATION AND ISOTOPES

A heparin-like compound isolated from a marine crab rich in glucuronic acid 2-O-sulfate presents low anticoagulant activity

(2013) Giulianna P.V. Andrade et al.   CARBOHYDRATE POLYMERS

The depolymerized fucosylated chondroitin sulfate from sea cucumber potently inhibits HIV replication via interfering with virus entry

(2013) Ning Huang et al.   CARBOHYDRATE RESEARCH

Frondoside A Suppressive Effects on Lung Cancer Survival, Tumor Growth, Angiogenesis, Invasion, and Metastasis

(2013) Samir Attoub et al.   PLoS One

Fucoidans from brown seaweeds: an update on structures, extraction techniques and use of enzymes as tools for structural elucidation

(2013) Marcel Tutor Ale et al.   RSC Advances

Antifungal effect and mechanism of chitosan against the rice sheath blight pathogen, Rhizoctonia solani

(2012) He Liu et al.   BIOTECHNOLOGY LETTERS

Molecular characteristics and anti-inflammatory activity of the fucoidan extracted from Ecklonia cava

(2012) Seung-Hong Lee et al.   CARBOHYDRATE POLYMERS

Anticancer activity of chemically prepared shrimp low molecular weight chitin evaluation with the human monocyte leukaemia cell line, THP-1

(2012) R. Salah et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Glycosides from Marine Sponges (Porifera, Demospongiae): Structures, Taxonomical Distribution, Biological Activities and Biological Roles

(2012) Vladimir I. Kalinin et al.   Marine Drugs

Aurantoside K, a New Antifungal Tetramic Acid Glycoside from a Fijian Marine Sponge of the Genus Melophlus

(2012) Rohitesh Kumar et al.   Marine Drugs

Immunostimulatory Effect of Laminarin on RAW 264.7 Mouse Macrophages

(2012) Ji Young Lee et al.   MOLECULES

Anti-inflammatory and antioxidant potential of alginic acid isolated from the marine algae, Sargassum wightii on adjuvant-induced arthritic rats

(2012) C. H. Sarithakumari et al.   INFLAMMOPHARMACOLOGY

Fucoidans from Brown Seaweeds Sargassum hornery, Eclonia cava, Costaria costata: Structural Characteristics and Anticancer Activity

(2011) Svetlana Ermakova et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Gold from the sea: Marine compounds as inhibitors of the hallmarks of cancer

(2011) Marc Schumacher et al.   BIOTECHNOLOGY ADVANCES

Frondoside A inhibits breast cancer metastasis and antagonizes prostaglandin E receptors EP4 and EP2

(2011) Xinrong Ma et al.   BREAST CANCER RESEARCH AND TREATMENT

Sulfated polysaccharides from brown seaweeds Saccharina japonica and Undaria pinnatifida: isolation, structural characteristics, and antitumor activity

(2011) Olesya S. Vishchuk et al.   CARBOHYDRATE RESEARCH

Chitosan Derivatives with Antimicrobial, Antitumour and Antioxidant Activities - a Review

(2011) Jarmila Vinsova et al.   CURRENT PHARMACEUTICAL DESIGN

Marine organisms as a therapeutic source against herpes simplex virus infection

(2011) Thanh-Sang Vo et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Frondoside A inhibits human breast cancer cell survival, migration, invasion and the growth of breast tumor xenografts

(2011) Nadia Al Marzouqi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ascidian dermatan sulfates attenuate metastasis, inflammation and thrombosis by inhibition of P-selectin

(2011) E. O. KOZLOWSKI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Therapies from Fucoidan; Multifunctional Marine Polymers

(2011) Janet Helen Fitton   Marine Drugs

Alginate: Properties and biomedical applications

(2011) Kuen Yong Lee et al.   PROGRESS IN POLYMER SCIENCE

Antinociceptive and Anti-inflammatory Activities of Lectin from Marine Red Alga Pterocladiella capillacea

(2010) Luana Maria Castelo Melo Silva et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Unique Extracellular Matrix Heparan Sulfate from the BivalveNodipecten nodosus(Linnaeus, 1758) Safely Inhibits Arterial Thrombosis after Photochemically Induced Endothelial Lesion

(2010) Angélica M. Gomes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A heparin mimetic isolated from a marine shrimp suppresses neovascularization

(2010) J. L. DREYFUSS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Carijoside A, a Bioactive Sterol Glycoside from an Octocoral Carijoa sp. (Clavulariidae)

(2010) Chih-Yang Liu et al.   Marine Drugs

Application of Spectroscopic Methods for Structural Analysis of Chitin and Chitosan

(2010) Jolanta Kumirska et al.   Marine Drugs

Structural characterization of laminaran and galactofucan extracted from the brown seaweed Saccharina longicruris

(2010) Laurie-Eve Rioux et al.   PHYTOCHEMISTRY

Iota-Carrageenan Is a Potent Inhibitor of Influenza A Virus Infection

(2010) Andreas Leibbrandt et al.   PLoS One

Fat and Fatty Acid Terminology, Methods of Analysis and Fat Digestion and Metabolism: A Background Review Paper

(2009) W.M. Nimal Ratnayake et al.   ANNALS OF NUTRITION AND METABOLISM

Novel Imino Sugar Derivatives Demonstrate Potent Antiviral Activity against Flaviviruses

(2009) J. Chang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pilot clinical study to evaluate the anticoagulant activity of fucoidan

(2009) Mohammad R Irhimeh et al.   BLOOD COAGULATION & FIBRINOLYSIS

Carrageenans: Biological properties, chemical modifications and structural analysis – A review

(2009) Vanessa Leiria Campo et al.   CARBOHYDRATE POLYMERS

Structural and functional insights into sulfated galactans: a systematic review

(2009) Vitor H. Pomin   GLYCOCONJUGATE JOURNAL

Bioactive alginate coatings to control Listeria monocytogenes on cold-smoked salmon slices and fillets

(2009) Hudaa Neetoo et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Inhibitors of Oxidation and Matrix Metalloproteinases, Floridoside, andd-Isofloridoside from Marine Red AlgaLaurencia undulata

(2009) Yong-Xin Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Unfractionated Heparin and New Heparin Analogues from Ascidians (Chordate-Tunicate) Ameliorate Colitis in Rats

(2009) Celso L. R. Belmiro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

From carbohydrate leads to glycomimetic drugs

(2009) Beat Ernst et al.   NATURE REVIEWS DRUG DISCOVERY

Effect of season on the composition of bioactive polysaccharides from the brown seaweed Saccharina longicruris

(2009) Laurie-Eve Rioux et al.   PHYTOCHEMISTRY

Fucoidans and fucoidanases—focus on techniques for molecular structure elucidation and modification of marine polysaccharides

(2008) Andrea Désirée Holtkamp et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Structure and anti-dengue virus activity of sulfated polysaccharide from a marine alga

(2008) Kazuya I.P.J. Hidari et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anti-inflammatory properties of a heparin-like glycosaminoglycan with reduced anti-coagulant activity isolated from a marine shrimp

(2008) Adriana S. Brito et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structural characterization and antithrombin activity of dermatan sulfate purified from marine clam Scapharca inaequivalvis

(2008) N. Volpi et al.   GLYCOBIOLOGY

Structure, biology, evolution, and medical importance of sulfated fucans and galactans

(2008) V. H Pomin et al.   GLYCOBIOLOGY

Drug development from marine natural products

(2008) Tadeusz F. Molinski et al.   NATURE REVIEWS DRUG DISCOVERY