Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases—Not Glycolipid Processing Enzymes
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases—Not Glycolipid Processing Enzymes
Authors
Keywords
Enzyme inhibitors, Glycolipids, Dengue virus, Glycoproteins, Endoplasmic reticulum, Cell cultures, Mouse models, Animal models of infection
Journal
PLoS Neglected Tropical Diseases
Volume 10, Issue 3, Pages e0004524
Publisher
Public Library of Science (PLoS)
Online
2016-03-15
DOI
10.1371/journal.pntd.0004524
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mutation of Putative N-Glycosylation Sites on Dengue Virus NS4B Decreases RNA Replication
- (2015) Nenavath Gopal Naik et al. JOURNAL OF VIROLOGY
- Dengue Virus- and Hepatitis C Virus-Induced Replication and Assembly Compartments: the Enemy Inside--Caught in the Web
- (2014) L. Chatel-Chaix et al. JOURNAL OF VIROLOGY
- Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial
- (2014) Jenny G Low et al. LANCET INFECTIOUS DISEASES
- Cellular Oxidative Stress Response Controls the Antiviral and Apoptotic Programs in Dengue Virus-Infected Dendritic Cells
- (2014) David Olagnier et al. PLoS Pathogens
- Monocyte Recruitment to the Dermis and Differentiation to Dendritic Cells Increases the Targets for Dengue Virus Replication
- (2014) Michael A. Schmid et al. PLoS Pathogens
- An iminosugar with potent inhibition of dengue virus infection in vivo
- (2013) Stuart T. Perry et al. ANTIVIRAL RESEARCH
- Antiviral therapies targeting host ER alpha-glucosidases: Current status and future directions
- (2013) Jinhong Chang et al. ANTIVIRAL RESEARCH
- Structure of the Lectin Mannose 6-Phosphate Receptor Homology (MRH) Domain of Glucosidase II, an Enzyme That Regulates Glycoprotein Folding Quality Control in the Endoplasmic Reticulum
- (2013) Linda J. Olson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Innate Immunity to Dengue Virus Infection and Subversion of Antiviral Responses
- (2013) Angela M. Green et al. JOURNAL OF MOLECULAR BIOLOGY
- Liposome-Mediated Delivery of Iminosugars Enhances Efficacy against Dengue VirusIn Vivo
- (2012) Joanna L. Miller et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial
- (2012) Satoru Watanabe et al. ANTIVIRAL RESEARCH
- Scalable Syntheses of Both Enantiomers of DNJNAc and DGJNAc from Glucuronolactone: The Effect of N-Alkylation on Hexosaminidase Inhibition
- (2012) Andreas F. G. Glawar et al. CHEMISTRY-A EUROPEAN JOURNAL
- Miglustat as a therapeutic agent: prospects and caveats
- (2012) Rosemarie E Venier et al. JOURNAL OF MEDICAL GENETICS
- Design, Synthesis, and Biological Evaluation of N-Alkylated Deoxynojirimycin (DNJ) Derivatives for the Treatment of Dengue Virus Infection
- (2012) Wenquan Yu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model
- (2011) Abhay P.S. Rathore et al. ANTIVIRAL RESEARCH
- Dengue virus PrM/M proteins fail to show pH-dependent ion channel activity in Xenopus oocytes
- (2011) Sook-San Wong et al. VIROLOGY
- Inhibitors of Endoplasmic Reticulum α-Glucosidases Potently Suppress Hepatitis C Virus Virion Assembly and Release
- (2010) Xiaowang Qu et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo
- (2010) Jinhong Chang et al. ANTIVIRAL RESEARCH
- Dengue virus type 2 recognizes the carbohydrate moiety of neutral glycosphingolipids in mammalian and mosquito cells
- (2010) Sineewanlaya Wichit et al. MICROBIOLOGY AND IMMUNOLOGY
- Targeting a host process as an antiviral approach against dengue virus
- (2010) Andrew C. Sayce et al. TRENDS IN MICROBIOLOGY
- Lethal Antibody Enhancement of Dengue Disease in Mice Is Prevented by Fc Modification
- (2010) Scott J. Balsitis et al. PLoS Pathogens
- Novel Imino Sugar Derivatives Demonstrate Potent Antiviral Activity against Flaviviruses
- (2009) J. Chang et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Composition and Three-Dimensional Architecture of the Dengue Virus Replication and Assembly Sites
- (2009) Sonja Welsch et al. Cell Host & Microbe
- Iminosugars in Combination with Interferon and Ribavirin Permanently Eradicate Noncytopathic Bovine Viral Diarrhea Virus from Persistently Infected Cells
- (2008) S. D. Woodhouse et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Interaction of dengue virus envelope protein with endoplasmic reticulum-resident chaperones facilitates dengue virus production
- (2008) Thawornchai Limjindaporn et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Glucosylated free oligosaccharides are biomarkers of endoplasmic- reticulum α-glucosidase inhibition
- (2008) Dominic S. Alonzi et al. BIOCHEMICAL JOURNAL
- The Mannose Receptor Mediates Dengue Virus Infection of Macrophages
- (2008) Joanna L. Miller et al. PLoS Pathogens
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started