Reproducible Construction of Surface Tension-Mediated Honeycomb Concave Microwell Arrays for Engineering of 3D Microtissues with Minimal Cell Loss

Immune-protected xenogeneic bioartificial livers with liver-specific microarchitecture and hydrogel-encapsulated cells

(2014) Da Yoon No et al.   BIOMATERIALS

Optimizing human embryonic stem cells differentiation efficiency by screening size-tunable homogenous embryoid bodies

(2014) Sung-Hwan Moon et al.   BIOMATERIALS

Quasi-spherical microwells on superhydrophobic substrates for long term culture of multicellular spheroids and high throughput assays

(2014) Tianqing Liu et al.   BIOMATERIALS

A microfluidic-based platform for tumour spheroid culture, monitoring and drug screening

(2014) K. Kwapiszewska et al.   LAB ON A CHIP

Microfluidics-generated pancreatic islet microfibers for enhanced immunoprotection

(2013) Yesl Jun et al.   BIOMATERIALS

3D co-culturing model of primary pancreatic islets and hepatocytes in hybrid spheroid to overcome pancreatic cell shortage

(2013) Yesl Jun et al.   BIOMATERIALS

Spheroid-based three-dimensional liver-on-a-chip to investigate hepatocyte–hepatic stellate cell interactions and flow effects

(2013) Seung-A Lee et al.   LAB ON A CHIP

Application of Concave Microwells to Pancreatic Tumor Spheroids Enabling Anticancer Drug Evaluation in a Clinically Relevant Drug Resistance Model

(2013) Sang-Eun Yeon et al.   PLoS One

Deconstructing Dimensionality

(2013) M. A. Schwartz et al.   SCIENCE

Spheroid culture as a tool for creating 3D complex tissues

(2013) Eelco Fennema et al.   TRENDS IN BIOTECHNOLOGY

Microfabricated Biomaterials for Engineering 3D Tissues

(2012) Pinar Zorlutuna et al.   ADVANCED MATERIALS

Multi-cell type human liver microtissues for hepatotoxicity testing

(2012) S. Messner et al.   ARCHIVES OF TOXICOLOGY

3D spheroid culture of hESC/hiPSC-derived hepatocyte-like cells for drug toxicity testing

(2012) Kazuo Takayama et al.   BIOMATERIALS

Rapid fabrication of a microdevice with concave microwells and its application in embryoid body formation

(2012) Youchun Xu et al.   Biomicrofluidics

Chondrocyte spheroids on microfabricated PEG hydrogel surface and their noninvasive functional monitoring

(2012) Hidenori Otsuka et al.   SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

Surface Tension-Mediated, Concave-Microwell Arrays for Large-Scale, Simultaneous Production of Homogeneously Sized Embryoid Bodies

(2012) Gi Seok Jeong et al.   Advanced Healthcare Materials

Three-dimensional cell culture based on microfluidic techniques to mimic living tissues

(2012) Yuya Morimoto et al.   Biomaterials Science

Concave microwell based size-controllable hepatosphere as a three-dimensional liver tissue model

(2011) Sau Fung Wong et al.   BIOMATERIALS

In situ formation and collagen-alginate composite encapsulation of pancreatic islet spheroids

(2011) Bo Ram Lee et al.   BIOMATERIALS

Biomimetic tissues on a chip for drug discovery

(2011) Amir M. Ghaemmaghami et al.   DRUG DISCOVERY TODAY

Diffusion-mediated in situ alginate encapsulation of cell spheroids using microscale concave well and nanoporous membrane

(2011) Kwang Ho Lee et al.   LAB ON A CHIP

Meniscus induced self organization of multiple deep concave wells in a microchannel for embryoid bodies generation

(2011) Gi Seok Jeong et al.   LAB ON A CHIP

Functional clustering of pancreatic islet cells using concave microwell array

(2011) Jin Wook Hwang et al.   MACROMOLECULAR RESEARCH

Micro-Masonry: Construction of 3D Structures by Microscale Self-Assembly

(2010) Javier G. Fernandez et al.   ADVANCED MATERIALS

Controlled-size embryoid body formation in concave microwell arrays

(2010) Yoon Young Choi et al.   BIOMATERIALS

Soft lithography for micro- and nanoscale patterning

(2010) Dong Qin et al.   Nature Protocols

3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cells

(2009) Wenjie Wang et al.   BIOMATERIALS

Comparative Analysis of Gene Expression in Rat Liver Tissue and Monolayer- and Spheroid-Cultured Hepatocytes

(2009) Yusuke Sakai et al.   CELLS TISSUES ORGANS

Inverted pattern formation of cell microarrays on poly(ethylene glycol) (PEG) gel patterned surface and construction of hepatocyte spheroids on unmodified PEG gel microdomains

(2009) Keitaro Yoshimoto et al.   LAB ON A CHIP

Ice-lithographic fabrication of concave microwells and a microfluidic network

(2008) Joong Yull Park et al.   BIOMEDICAL MICRODEVICES

Recent advances in three-dimensional multicellular spheroid culture for biomedical research

(2008) Ruei-Zhen Lin et al.   Biotechnology Journal

Micropatterned organoid culture of rat hepatocytes and HepG2 cells

(2008) Ryuhei Mori et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING