Transcriptional profile and Epstein-Barr virus infection status of laser-cut immune infiltrates from the brain of patients with progressive multiple sclerosis

The role of peripheral immune cells in the CNS in steady state and disease

(2017) Marco Prinz et al.   NATURE NEUROSCIENCE

Memory B Cells are Major Targets for Effective Immunotherapy in Relapsing Multiple Sclerosis

(2017) David Baker et al.   EBioMedicine

Current multiple sclerosis treatments have improved our understanding of MS autoimmune pathogenesis

(2016) Roland Martin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Central Nervous System Stromal Cells Control Local CD8 + T Cell Responses during Virus-Induced Neuroinflammation

(2016) Jovana Cupovic et al.   IMMUNITY

Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection

(2016) Karin Steinbach et al.   JOURNAL OF EXPERIMENTAL MEDICINE

RORγt Expression and Lymphoid Neogenesis in the Brain of Patients with Secondary Progressive Multiple Sclerosis

(2016) Barbara Serafini et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Interactions between genetic, lifestyle and environmental risk factors for multiple sclerosis

(2016) Tomas Olsson et al.   Nature Reviews Neurology

Myeloid cells — targets of medication in multiple sclerosis

(2016) Manoj K. Mishra et al.   Nature Reviews Neurology

Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier

(2016) H. Gerwien et al.   Science Translational Medicine

Meningeal Tertiary Lymphoid Tissues and Multiple Sclerosis: A Gathering Place for Diverse Types of Immune Cells during CNS Autoimmunity

(2016) Natalia B. Pikor et al.   Frontiers in Immunology

High-throughput sequencing of immune repertoires in multiple sclerosis

(2016) Andreas Lossius et al.   Annals of Clinical and Translational Neurology

The Immunology of Epstein-Barr Virus–Induced Disease

(2015) Graham S. Taylor et al.   Annual Review of Immunology

The 3 major types of innate and adaptive cell-mediated effector immunity

(2015) Francesco Annunziato et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A Gene Expression Signature That Correlates with CD8+T Cell Expansion in Acute EBV Infection

(2015) Thomas C. Greenough et al.   JOURNAL OF IMMUNOLOGY

Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-β Therapy

(2015) Javad Rasouli et al.   JOURNAL OF IMMUNOLOGY

Immune and Epstein-Barr virus gene expression in cerebrospinal fluid and peripheral blood mononuclear cells from patients with relapsing-remitting multiple sclerosis

(2015) Caterina Veroni et al.   Journal of Neuroinflammation

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

Intrathecal CD8 T-cells of multiple sclerosis patients recognize lytic Epstein-Barr virus proteins

(2015) Gijsbert P van Nierop et al.   Multiple Sclerosis Journal

GM-CSF in Neuroinflammation: Licensing Myeloid Cells for Tissue Damage

(2015) Andrew L. Croxford et al.   TRENDS IN IMMUNOLOGY

Intrathecal CD8 T-cells of multiple sclerosis patients recognize lytic Epstein-Barr virus proteins

(2015) Gijsbert P van Nierop et al.   Multiple Sclerosis Journal

Role of Human Natural Killer Cells during Epstein-Barr Virus Infection

(2014) Christian Muenz   CRITICAL REVIEWS IN IMMUNOLOGY

Epstein-Barr Virus in the Central Nervous System and Cervical Lymph Node of a Patient With Primary Progressive Multiple Sclerosis

(2014) Barbara Serafini et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

IL-17 and GM-CSF Expression Are Antagonistically Regulated by Human T Helper Cells

(2014) R. Noster et al.   Science Translational Medicine

The Role of Myeloid Cell Activation and Arginine Metabolism in the Pathogenesis of Virus-Induced Diseases

(2014) Kristina S. Burrack et al.   Frontiers in Immunology

Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized rats

(2013) Christopher Gardner et al.   BRAIN

Radioactive in situ hybridization for Epstein–Barr virus–encoded small RNA supports presence of Epstein–Barr virus in the multiple sclerosis brain

(2013) Barbara Serafini et al.   BRAIN

CD8+T cells in multiple sclerosis

(2013) Aleksandar Denic et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Environmental factors in multiple sclerosis

(2013) Alberto Ascherio   Expert Review of Neurotherapeutics

The interferon response to intracellular DNA: Why so many receptors?

(2013) Leonie Unterholzner   IMMUNOBIOLOGY

Increased CD8+ T Cell Response to Epstein-Barr Virus Lytic Antigens in the Active Phase of Multiple Sclerosis

(2013) Daniela F. Angelini et al.   PLoS Pathogens

Interleukin 35: A Key Mediator of Suppression and the Propagation of Infectious Tolerance

(2013) Brian M. Olson et al.   Frontiers in Immunology

Natural killer cells and their receptors in multiple sclerosis

(2012) Gurman Kaur et al.   BRAIN

The innate immune system in demyelinating disease

(2012) Lior Mayo et al.   IMMUNOLOGICAL REVIEWS

The Molecular Signature of Tissue Resident Memory CD8 T Cells Isolated from the Brain

(2012) L. M. Wakim et al.   JOURNAL OF IMMUNOLOGY

B-Cell Enrichment and Epstein-Barr Virus Infection in Inflammatory Cortical Lesions in Secondary Progressive Multiple Sclerosis

(2012) Roberta Magliozzi et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Epstein-Barr virus in the multiple sclerosis brain: a controversial issue--report on a focused workshop held in the Centre for Brain Research of the Medical University of Vienna, Austria

(2011) H. Lassmann et al.   BRAIN

Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis

(2011) Owain W. Howell et al.   BRAIN

IRF7: activation, regulation, modification and function

(2011) S Ning et al.   GENES AND IMMUNITY

Epstein-Barr virus and multiple sclerosis

(2011) R. M. Lucas et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis

(2010) Roberta Magliozzi et al.   ANNALS OF NEUROLOGY

Epstein-Barr Virus Latent Infection and BAFF Expression in B Cells in the Multiple Sclerosis Brain: Implications for Viral Persistence and Intrathecal B-Cell Activation

(2010) Barbara Serafini et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Absence of Epstein-Barr virus in the brain and CSF of patients with multiple sclerosis

(2010) S. A. Sargsyan et al.   NEUROLOGY

Collateral Bystander Damage by Myelin-Directed CD8+ T Cells Causes Axonal Loss

(2009) Bettina Sobottka et al.   AMERICAN JOURNAL OF PATHOLOGY

Preferential recruitment of interferon-γ-expressing TH17 cells in multiple sclerosis

(2009) Hania Kebir et al.   ANNALS OF NEUROLOGY

Epstein Barr virus is not a characteristic feature in the central nervous system in established multiple sclerosis

(2009) Laura A. N. Peferoen et al.   BRAIN

Epstein–Barr virus infection is not a characteristic feature of multiple sclerosis brain

(2009) Simon N. Willis et al.   BRAIN

The relation between inflammation and neurodegeneration in multiple sclerosis brains

(2009) Josa M. Frischer et al.   BRAIN

Epstein–Barr virus and multiple sclerosis

(2009) Marco Salvetti et al.   CURRENT OPINION IN NEUROLOGY

Intrathecal immune responses to EBV in early MS

(2009) Emilie Jaquiéry et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Plasmacytoid Dendritic Cells in Multiple Sclerosis

(2009) Roberto Lande et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

EBV in MS: guilty by association?

(2009) Jan D. Lünemann et al.   TRENDS IN IMMUNOLOGY

CD1a expression defines an interleukin-12 producing population of human dendritic cells

(2008) M. Cernadas et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis

(2007) John S. Tzartos et al.   AMERICAN JOURNAL OF PATHOLOGY

The blood-brain barrier induces differentiation of migrating monocytes into Th17-polarizing dendritic cells

(2007) I. Ifergan et al.   BRAIN