Interactions between genetic, lifestyle and environmental risk factors for multiple sclerosis

Migration and multiple sclerosis in immigrants from United Kingdom and Ireland to Australia: a reassessment. III: risk of multiple sclerosis in UKI immigrants and Australian-born in Hobart, Tasmania

(2016) Michael H. Barnett et al.   JOURNAL OF NEUROLOGY

High consumption of coffee is associated with decreased multiple sclerosis risk; results from two independent studies

(2016) A K Hedström et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Obesity and Multiple Sclerosis: A Mendelian Randomization Study

(2016) Lauren E. Mokry et al.   PLOS MEDICINE

Vitamin D Status During Pregnancy and Risk of Multiple Sclerosis in Offspring of Women in the Finnish Maternity Cohort

(2016) Kassandra L. Munger et al.   JAMA Neurology

Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses

(2015) Mauricio F. Farez et al.   CELL

Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

(2015) Petter Brodin et al.   CELL

Smoking worsens multiple sclerosis prognosis: Two different pathways are involved

(2015) Jorge Correale et al.   JOURNAL OF NEUROIMMUNOLOGY

Leptin in autoimmune diseases

(2015) Claudio Procaccini et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Smoking is a major preventable risk factor for multiple sclerosis

(2015) AK Hedström et al.   Multiple Sclerosis Journal

Vitamin D and axonal injury in multiple sclerosis

(2015) L Sandberg et al.   Multiple Sclerosis Journal

Viral exposures and MS outcome in a prospective cohort of children with acquired demyelination

(2015) Naila Makhani et al.   Multiple Sclerosis Journal

Timing of use of cod liver oil, a vitamin D source, and multiple sclerosis risk: The EnvIMS study

(2015) Marianna Cortese et al.   Multiple Sclerosis Journal

Shift work influences multiple sclerosis risk

(2015) AK Hedström et al.   Multiple Sclerosis Journal

Body mass index during adolescence, rather than childhood, is critical in determining MS risk

(2015) AK Hedström et al.   Multiple Sclerosis Journal

Population attributable fractions and joint effects of key risk factors for multiple sclerosis

(2015) IAF van der Mei et al.   Multiple Sclerosis Journal

Class II HLA interactions modulate genetic risk for multiple sclerosis

(2015) Loukas Moutsianas et al.   NATURE GENETICS

Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study

(2015) Lauren E. Mokry et al.   PLOS MEDICINE

Genome-wide DNA methylation profiling of CD8+ T cells shows a distinct epigenetic signature to CD4+ T cells in multiple sclerosis patients

(2015) Vicki E. Maltby et al.   Clinical Epigenetics

DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies

(2015) Xu Gao et al.   Clinical Epigenetics

Effect of Smoking Cessation on Multiple Sclerosis Prognosis

(2015) Ryan Ramanujam et al.   JAMA Neurology

Association of Vitamin D Levels With Multiple Sclerosis Activity and Progression in Patients Receiving Interferon Beta-1b

(2015) Kathryn C. Fitzgerald et al.   JAMA Neurology

Smoking is a major preventable risk factor for multiple sclerosis

(2015) AK Hedström et al.   Multiple Sclerosis Journal

Vitamin D and axonal injury in multiple sclerosis

(2015) L Sandberg et al.   Multiple Sclerosis Journal

Viral exposures and MS outcome in a prospective cohort of children with acquired demyelination

(2015) Naila Makhani et al.   Multiple Sclerosis Journal

Timing of use of cod liver oil, a vitamin D source, and multiple sclerosis risk: The EnvIMS study

(2015) Marianna Cortese et al.   Multiple Sclerosis Journal

Shift work influences multiple sclerosis risk

(2015) AK Hedström et al.   Multiple Sclerosis Journal

Body mass index during adolescence, rather than childhood, is critical in determining MS risk

(2015) AK Hedström et al.   Multiple Sclerosis Journal

Population attributable fractions and joint effects of key risk factors for multiple sclerosis

(2015) IAF van der Mei et al.   Multiple Sclerosis Journal

Genome-Wide DNA Methylation Profiles Indicate CD8+ T Cell Hypermethylation in Multiple Sclerosis

(2015) Steffan D. Bos et al.   PLoS One

GeMes, Clusters of DNA Methylation under Genetic Control, Can Inform Genetic and Epigenetic Analysis of Disease

(2014) Yun Liu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Neonatal vitamin D status and risk of multiple sclerosis

(2014) Peter Ueda et al.   ANNALS OF NEUROLOGY

Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity

(2014) Johanna Breuer et al.   ANNALS OF NEUROLOGY

Modest familial risks for multiple sclerosis: a registry-based study of the population of Sweden

(2014) Helga Westerlind et al.   BRAIN

Smoking and Risk of Multiple Sclerosis

(2014) Farren B. S. Briggs et al.   EPIDEMIOLOGY

Identity-by-descent mapping in a Scandinavian multiple sclerosis cohort

(2014) Helga Westerlind et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Obesity interacts with infectious mononucleosis in risk of multiple sclerosis

(2014) A. K. Hedström et al.   EUROPEAN JOURNAL OF NEUROLOGY

Interaction between passive smoking and two HLA genes with regard to multiple sclerosis risk

(2014) Anna Karin Hedström et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Tobacco smoking and excess mortality in multiple sclerosis: a cohort study

(2014) Ali Manouchehrinia et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Sodium intake is associated with increased disease activity in multiple sclerosis

(2014) Mauricio F Farez et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Sun exposure and multiple sclerosis risk in Norway and Italy: The EnvIMS study

(2014) Kjetil Bjørnevik et al.   Multiple Sclerosis Journal

Prevalence of multiple sclerosis among immigrants in Norway

(2014) Pål Berg-Hansen et al.   Multiple Sclerosis Journal

New data identify an increasing sex ratio of multiple sclerosis in Sweden

(2014) Helga Westerlind et al.   Multiple Sclerosis Journal

Body size and the risk of multiple sclerosis in Norway and Italy: The EnvIMS study

(2014) Kristin Wesnes et al.   Multiple Sclerosis Journal

Potential Impact of Air Pollution on Multiple Sclerosis in Tehran, Iran

(2014) Pouria Heydarpour et al.   NEUROEPIDEMIOLOGY

Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis

(2014) A. K. Hedstrom et al.   NEUROLOGY

Obesity during childhood and adolescence increases susceptibility to multiple sclerosis after accounting for established genetic and environmental risk factors

(2014) Milena A. Gianfrancesco et al.   Obesity Research & Clinical Practice

JC Polyomavirus Infection Is Strongly Controlled by Human Leucocyte Antigen Class II Variants

(2014) Emilie Sundqvist et al.   PLoS Pathogens

Alcohol as a Modifiable Lifestyle Factor Affecting Multiple Sclerosis Risk

(2014) Anna Karin Hedström et al.   JAMA Neurology

Vitamin D as an Early Predictor of Multiple Sclerosis Activity and Progression

(2014) Alberto Ascherio et al.   JAMA Neurology

Molecular mechanism underlying the impact of vitamin D on disease activity of MS

(2014) Kassandra L. Munger et al.   Annals of Clinical and Translational Neurology

Tobacco smoking and disability progression in multiple sclerosis: United Kingdom cohort study

(2013) Ali Manouchehrinia et al.   BRAIN

Early-life hygiene-related factors affect risk of central nervous system demyelination and asthma differentially

(2013) A.-M. Hughes et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Efficacy of vitamin D in treating multiple sclerosis-like neuroinflammation depends on developmental stage

(2013) Milena Z. Adzemovic et al.   EXPERIMENTAL NEUROLOGY

The Aryl Hydrocarbon Receptor Is Involved in UVR-Induced Immunosuppression

(2013) Fatemeh Navid et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Modulation of multiple sclerosis by sunlight exposure: Role of cis-urocanic acid

(2013) Jorge Correale et al.   JOURNAL OF NEUROIMMUNOLOGY

Cytomegalovirus seropositivity is negatively associated with multiple sclerosis

(2013) E Sundqvist et al.   Multiple Sclerosis Journal

Smoking and risk of treatment-induced neutralizing antibodies to interferon β-1a

(2013) Anna Karin Hedström et al.   Multiple Sclerosis Journal

Fatty fish intake is associated with decreased occurrence of multiple sclerosis

(2013) Maria Bäärnhielm et al.   Multiple Sclerosis Journal

Reproduction and the risk of multiple sclerosis

(2013) Melinda Magyari et al.   Multiple Sclerosis Journal

Reverse causality behind the association between reproductive history and MS

(2013) AK Hedström et al.   Multiple Sclerosis Journal

Methylation differences at the HLA-DRB1 locus in CD4+ T-Cells are associated with multiple sclerosis

(2013) MC Graves et al.   Multiple Sclerosis Journal

Childhood body mass index and multiple sclerosis risk: a long-term cohort study

(2013) Kassandra L Munger et al.   Multiple Sclerosis Journal

Smokers run increased risk of developing anti-natalizumab antibodies

(2013) AK Hedström et al.   Multiple Sclerosis Journal

Nicotine might have a protective effect in the etiology of multiple sclerosis

(2013) AK Hedström et al.   Multiple Sclerosis Journal

Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1

(2013) Chuan Wu et al.   NATURE

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

(2013) Markus Kleinewietfeld et al.   NATURE

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

(2013) Ashley H Beecham et al.   NATURE GENETICS

Epigenome-wide differences in pathology-free regions of multiple sclerosis–affected brains

(2013) Jimmy L Huynh et al.   NATURE NEUROSCIENCE

Childhood obesity and risk of pediatric multiple sclerosis and clinically isolated syndrome

(2013) A. Langer-Gould et al.   NEUROLOGY

Overweight and obese adult humans have a defective cellular immune response to pandemic H1N1 Influenza a virus

(2013) Heather A. Paich et al.   Obesity

Sunlight is associated with decreased multiple sclerosis risk: no interaction with human leukocyte antigen-DRB1*15

(2012) M. Bäärnhielm et al.   EUROPEAN JOURNAL OF NEUROLOGY

Shared genetic factors may not explain the raised risk of comorbid inflammatory diseases in multiple sclerosis

(2012) H Roshanisefat et al.   Multiple Sclerosis Journal

Antibody response to common viruses and human leukocyte antigen-DRB1 in pediatric multiple sclerosis

(2012) Emmanuelle Waubant et al.   Multiple Sclerosis Journal

High rates of physician services utilization at least five years before multiple sclerosis diagnosis

(2012) Ruth Ann Marrie et al.   Multiple Sclerosis Journal

Caffeine and alcohol intakes have no association with risk of multiple sclerosis

(2012) J Massa et al.   Multiple Sclerosis Journal

Smoking as a risk factor for multiple sclerosis

(2012) Jonatan Salzer et al.   Multiple Sclerosis Journal

T cells become licensed in the lung to enter the central nervous system

(2012) Francesca Odoardi et al.   NATURE

The initiation and prevention of multiple sclerosis

(2012) Alberto Ascherio et al.   Nature Reviews Neurology

Modelling Genetic Susceptibility to Multiple Sclerosis with Family Data

(2012) Cullen O’Gorman et al.   NEUROEPIDEMIOLOGY

Offspring number, pregnancy, and risk of a first clinical demyelinating event: The AusImmune Study

(2012) A.- L. Ponsonby et al.   NEUROLOGY

Organic Solvents as Risk Factor for Autoimmune Diseases: A Systematic Review and Meta-Analysis

(2012) Carolina Barragán-Martínez et al.   PLoS One

Systemic Low-Dose UVB Inhibits CD8 T Cells and Skin Inflammation by Alternative and Novel Mechanisms

(2011) Sabita Rana et al.   AMERICAN JOURNAL OF PATHOLOGY

Shift work at young age is associated with increased risk for multiple sclerosis

(2011) Anna Karin Hedström et al.   ANNALS OF NEUROLOGY

Interaction of HLA-DRB1*03 and smoking for the development of anti-Jo-1 antibodies in adult idiopathic inflammatory myopathies: a European-wide case study

(2011) H Chinoy et al.   ANNALS OF THE RHEUMATIC DISEASES

Epstein-Barr virus in the multiple sclerosis brain: a controversial issue--report on a focused workshop held in the Centre for Brain Research of the Medical University of Vienna, Austria

(2011) H. Lassmann et al.   BRAIN

Smoking and two human leukocyte antigen genes interact to increase the risk for multiple sclerosis

(2011) Anna Karin Hedström et al.   BRAIN

Reproductive History and Risk of Multiple Sclerosis

(2011) Nete Munk Nielsen et al.   EPIDEMIOLOGY

The burden of obesity on infectious disease

(2011) Erik A Karlsson et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Epstein-Barr virus and multiple sclerosis: interaction with HLA

(2011) E Sundqvist et al.   GENES AND IMMUNITY

Latitude is significantly associated with the prevalence of multiple sclerosis: a meta-analysis

(2011) S. Simpson et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Changed Histone Acetylation Patterns in Normal-Appearing White Matter and Early Multiple Sclerosis Lesions

(2011) X. Pedre et al.   JOURNAL OF NEUROSCIENCE

A nationwide survey of the prevalence of multiple sclerosis in immigrant populations of Sweden

(2011) Cecilia Ahlgren et al.   Multiple Sclerosis Journal

The impact of environmental infections (parasites) on MS activity

(2011) Jorge Correale et al.   Multiple Sclerosis Journal

Exposure to environmental tobacco smoke is associated with increased risk for multiple sclerosis

(2011) AK Hedström et al.   Multiple Sclerosis Journal

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Common viruses associated with lower pediatric multiple sclerosis risk

(2011) E. Waubant et al.   NEUROLOGY

Smoking and Multiple Sclerosis: An Updated Meta-Analysis

(2011) Adam E. Handel et al.   PLoS One

Genetic Control of Individual Differences in Gene-Specific Methylation in Human Brain

(2010) Dandan Zhang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Pinealectomy ameliorates collagen II-induced arthritis in mice

(2010) I. HANSSON et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Confirmation of association between multiple sclerosis and CYP27B1

(2010) Emilie Sundqvist et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The changing demographic pattern of multiple sclerosis epidemiology

(2010) Nils Koch-Henriksen et al.   LANCET NEUROLOGY

High risk of MS in Iranian immigrants in Gothenburg, Sweden

(2010) C. Ahlgren et al.   Multiple Sclerosis Journal

Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis

(2010) Sergio E. Baranzini et al.   NATURE

Leptin as a metabolic link to multiple sclerosis

(2010) Giuseppe Matarese et al.   Nature Reviews Neurology

Multiple sclerosis, vitamin D, and HLA-DRB1*15

(2010) L. Handunnetthi et al.   NEUROLOGY

An Updated Meta-Analysis of Risk of Multiple Sclerosis following Infectious Mononucleosis

(2010) Adam E. Handel et al.   PLoS One

UV radiation suppresses experimental autoimmune encephalomyelitis independent of vitamin D production

(2010) B. R. Becklund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human leukocyte antigen-DR15, low infant sibling exposure and multiple sclerosis: Gene-environment interaction

(2009) Ingrid A. F. van der Mei et al.   ANNALS OF NEUROLOGY

Smoking and Disease Progression in Multiple Sclerosis

(2009) Brian C. Healy et al.   ARCHIVES OF NEUROLOGY

Chronic caffeine treatment attenuates experimental autoimmune encephalomyelitis induced by guinea pig spinal cord homogenates in Wistar rats

(2009) Guo Qian Chen et al.   BRAIN RESEARCH

Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals

(2009) S. Chidrawar et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Activation of the Cholinergic Anti-Inflammatory System by Nicotine Attenuates Neuroinflammation via Suppression of Th1 and Th17 Responses

(2009) E. Nizri et al.   JOURNAL OF IMMUNOLOGY

Antibodies to specific EBNA-1 domains and HLA DRB1⁎1501 interact as risk factors for multiple sclerosis☆

(2009) Peter Sundström et al.   JOURNAL OF NEUROIMMUNOLOGY

Smoking is associated with progressive disease course and increased progression in clinical disability in a prospective cohort of people with multiple sclerosis

(2009) Fotini Pittas et al.   JOURNAL OF NEUROLOGY

Rheumatoid arthritis

(2009) Lars Klareskog et al.   LANCET

Effects of infectious mononucleosis and HLA-DRB1*15 in multiple sclerosis

(2009) TR Nielsen et al.   Multiple Sclerosis Journal

Tobacco smoking, but not Swedish snuff use, increases the risk of multiple sclerosis

(2009) A. K. Hedstrom et al.   NEUROLOGY

Smoking is associated with increased lesion volumes and brain atrophy in multiple sclerosis

(2009) R. Zivadinov et al.   NEUROLOGY

Body size and risk of MS in two cohorts of US women

(2009) K. L. Munger et al.   NEUROLOGY

Lung Myeloid Dendritic Cells Coordinately Induce TH1 and TH17 Responses in Human Emphysema

(2009) M. Shan et al.   Science Translational Medicine

Alcohol consumption is associated with decreased risk of rheumatoid arthritis: results from two Scandinavian case-control studies

(2008) H Kallberg et al.   ANNALS OF THE RHEUMATIC DISEASES

The complex genetics of multiple sclerosis: pitfalls and prospects

(2008) Stephen Sawcer   BRAIN

Smoking is a risk factor for early conversion to clinically definite multiple sclerosis

(2008) F Di Pauli et al.   Multiple Sclerosis Journal

Smoking worsens the prognosis in multiple sclerosis

(2008) P Sundström et al.   Multiple Sclerosis Journal

Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis

(2008) Manuel A Friese et al.   NATURE MEDICINE

B-Cell Depletion with Rituximab in Relapsing–Remitting Multiple Sclerosis

(2008) Stephen L. Hauser et al.   NEW ENGLAND JOURNAL OF MEDICINE