STAT3 inhibitor NSC74859 radiosensitizes esophageal cancer via the downregulation of HIF-1α

A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppressive Activity in Human Cancer Cells

(2015) Li Lin et al.   NEOPLASIA

Berberine inhibits the expression of hypoxia induction factor-1alpha and increases the radiosensitivity of prostate cancer

(2014) Qu Zhang et al.   Diagnostic Pathology

Berberine radiosensitizes human nasopharyngeal carcinoma by suppressing hypoxia-inducible factor-1α expression

(2013) Chi Zhang et al.   ACTA OTO-LARYNGOLOGICA

Berberine enhances radiosensitivity of esophageal squamous cancer by targeting HIF-1α in vitro and in vivo

(2013) Xi Yang et al.   CANCER BIOLOGY & THERAPY

Hypoxia-Induced Snail Expression Through Transcriptional Regulation by HIF-1α in Pancreatic Cancer Cells

(2013) Guang-hui Zhu et al.   DIGESTIVE DISEASES AND SCIENCES

Stat3 Inhibitor Stattic Exhibits Potent Antitumor Activity and Induces Chemo- and Radio-Sensitivity in Nasopharyngeal Carcinoma

(2013) Yunbao Pan et al.   PLoS One

JAK/STAT signal pathway activation promotes progression and survival of human oesophageal squamous cell carcinoma

(2012) Zhenbing You et al.   Clinical & Translational Oncology

Cancer prevention by targeting angiogenesis

(2012) Adriana Albini et al.   Nature Reviews Clinical Oncology

Targeting STAT3 inhibits growth and enhances radiosensitivity in head and neck squamous cell carcinoma

(2012) Makoto Adachi et al.   ORAL ONCOLOGY

Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

(2012) Gregg L. Semenza   TRENDS IN PHARMACOLOGICAL SCIENCES

NSC 74859-mediated inhibition of STAT3 enhances the anti-proliferative activity of cetuximab in hepatocellular carcinoma

(2011) Wei Chen et al.   LIVER INTERNATIONAL

Hypoxia effects on proangiogenic factors in human umbilical vein endothelial cells: functional role of the peptide somatostatin

(2011) Massimo Dal Monte et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

A novel small-molecule disrupts Stat3 SH2 domain–phosphotyrosine interactions and Stat3-dependent tumor processes

(2010) Xiaolei Zhang et al.   BIOCHEMICAL PHARMACOLOGY

The STAT3 inhibitor NSC 74859 is effective in hepatocellular cancers with disrupted TGF-β signaling

(2009) L Lin et al.   ONCOGENE

Signal Transducer and Activator of Transcription 3 Is Required for Hypoxia-Inducible Factor-1  RNA Expression in Both Tumor Cells and Tumor-Associated Myeloid Cells

(2008) G. Niu et al.   MOLECULAR CANCER RESEARCH