DR2DI: a powerful computational tool for predicting novel drug-disease associations

Large-scale prediction of microRNA-disease associations by combinatorial prioritization algorithm

(2017) Hua Yu et al.   Scientific Reports

On the Integration of In Silico Drug Design Methods for Drug Repurposing

(2017) Eric March-Vila et al.   Frontiers in Pharmacology

Seeksv: an accurate tool for somatic structural variation and virus integration detection

(2016) Ying Liang et al.   BIOINFORMATICS

The Comparative Toxicogenomics Database: update 2017

(2016) Allan Peter Davis et al.   NUCLEIC ACIDS RESEARCH

In silico methods for drug repurposing and pharmacology

(2016) Rachel A. Hodos et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

A Novel Drug-Mouse Phenotypic Similarity Method Detects Molecular Determinants of Drug Effects

(2016) Jeanette Prinz et al.   PLoS Computational Biology

Systematic Drug Repositioning for a Wide Range of Diseases with Integrative Analyses of Phenotypic and Molecular Data

(2015) Hiroaki Iwata et al.   Journal of Chemical Information and Modeling

Drug repositioning by integrating target information through a heterogeneous network model

(2014) Wenhui Wang et al.   BIOINFORMATICS

Drug–Disease Association and Drug-Repositioning Predictions in Complex Diseases Using Causal Inference–Probabilistic Matrix Factorization

(2014) Jihong Yang et al.   Journal of Chemical Information and Modeling

Pathway-based Bayesian inference of drug–disease interactions

(2014) Naruemon Pratanwanich et al.   Molecular BioSystems

Construction of Drug Network Based on Side Effects and Its Application for Drug Repositioning

(2014) Hao Ye et al.   PLoS One

Molecularly and clinically related drugs and diseases are enriched in phenotypically similar drug-disease pairs

(2014) Ingo Vogt et al.   Genome Medicine

Mojo Hand, a TALEN design tool for genome editing applications

(2013) Kevin L Neff et al.   BMC BIOINFORMATICS

Inferring drug-disease associations from integration of chemical, genomic and phenotype data using network propagation

(2013) Yu-Fen Huang et al.   BMC Medical Genomics

Computational Drug Repositioning: From Data to Therapeutics

(2013) M R Hurle et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Prediction of human genes and diseases targeted by xenobiotics using predictive toxicogenomic-derived models (PTDMs)

(2013) Feixiong Cheng et al.   Molecular BioSystems

Network-based drug repositioning

(2013) Zikai Wu et al.   Molecular BioSystems

Rational drug repositioning by medical genetics

(2013) Zhong-Yi Wang et al.   NATURE BIOTECHNOLOGY

Drug Repositioning by Kernel-Based Integration of Molecular Structure, Molecular Activity, and Phenotype Data

(2013) Yongcui Wang et al.   PLoS One

Drug Repositioning: A Machine-Learning Approach through Data Integration

(2013) Francesco Napolitano et al.   Journal of Cheminformatics

A Systematic Prediction of Multiple Drug-Target Interactions from Chemical, Genomic, and Pharmacological Data

(2012) Hua Yu et al.   PLoS One

Using Functional Signatures to Identify Repositioned Drugs for Breast, Myelogenous Leukemia and Prostate Cancer

(2012) Daichi Shigemizu et al.   PLoS Computational Biology

Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference

(2012) Feixiong Cheng et al.   PLoS Computational Biology

Exploiting drug-disease relationships for computational drug repositioning

(2011) J. T. Dudley et al.   BRIEFINGS IN BIOINFORMATICS

PREDICT: a method for inferring novel drug indications with application to personalized medicine

(2011) A. Gottlieb et al.   Molecular Systems Biology

Systematic Drug Repositioning Based on Clinical Side-Effects

(2011) Lun Yang et al.   PLoS One

Discovery and Preclinical Validation of Drug Indications Using Compendia of Public Gene Expression Data

(2011) M. Sirota et al.   Science Translational Medicine

A variable selection method for genome-wide association studies

(2010) Qianchuan He et al.   BIOINFORMATICS

How to improve R&D productivity: the pharmaceutical industry's grand challenge

(2010) Steven M. Paul et al.   NATURE REVIEWS DRUG DISCOVERY

PROMISCUOUS: a database for network-based drug-repositioning

(2010) J. von Eichborn et al.   NUCLEIC ACIDS RESEARCH

Discovery of drug mode of action and drug repositioning from transcriptional responses

(2010) F. Iorio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Evaluation of Drug–Disease Relationships to Identify Leads for Novel Drug Uses

(2009) A P Chiang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Human Disease-Drug Network Based on Genomic Expression Profiles

(2009) Guanghui Hu et al.   PLoS One

Comparative Toxicogenomics Database: a knowledgebase and discovery tool for chemical-gene-disease networks

(2008) A. P. Davis et al.   NUCLEIC ACIDS RESEARCH