Inferring drug-disease associations from integration of chemical, genomic and phenotype data using network propagation

Predicting Chemical Toxicity Effects Based on Chemical-Chemical Interactions

(2013) Lei Chen et al.   PLoS One

Drug repositioning through incomplete bi-cliques in an integrated drug–target–disease network

(2012) Simone Daminelli et al.   Integrative Biology

Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference

(2012) Feixiong Cheng et al.   PLoS Computational Biology

PRINCIPLE: a tool for associating genes with diseases via network propagation

(2011) A. Gottlieb et al.   BIOINFORMATICS

LPS-Induced TLR4 Signaling in Human Colorectal Cancer Cells Increases  1 Integrin-Mediated Cell Adhesion and Liver Metastasis

(2011) R. Y. C. Hsu et al.   CANCER RESEARCH

Toll-like receptor genes and their association with colon and rectal cancer development and prognosis

(2011) Martha L. Slattery et al.   INTERNATIONAL JOURNAL OF CANCER

S100A8/A9 Activate Key Genes and Pathways in Colon Tumor Progression

(2011) M. Ichikawa et al.   MOLECULAR CANCER RESEARCH

PAR-4 as a possible new target for pancreatic cancer therapy

(2010) Asfar S Azmi et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Vitamin B6and Risk of Colorectal Cancer

(2010) Susanna C. Larsson et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

PROMISCUOUS: a database for network-based drug-repositioning

(2010) J. von Eichborn et al.   NUCLEIC ACIDS RESEARCH

The High Affinity IgE Receptor FcεRI Is Expressed by Human Intestinal Epithelial Cells

(2010) Eva Untersmayr et al.   PLoS One

Use of Data-Biased Random Walks on Graphs for the Retrieval of Context-Specific Networks from Genomic Data

(2010) Kakajan Komurov et al.   PLoS Computational Biology

Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets

(2010) Silpa Suthram et al.   PLoS Computational Biology

Associations of a Polymorphism in the Ornithine Decarboxylase Gene with Colorectal Cancer Survival

(2009) J. A. Zell et al.   CLINICAL CANCER RESEARCH

Systematic Evaluation of Drug–Disease Relationships to Identify Leads for Novel Drug Uses

(2009) A P Chiang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Evaluation of Microarray Preprocessing Algorithms Based on Concordance with RT-PCR in Clinical Samples

(2009) Balazs Gyorffy et al.   PLoS One

Human Disease-Drug Network Based on Genomic Expression Profiles

(2009) Guanghui Hu et al.   PLoS One

Building Disease-Specific Drug-Protein Connectivity Maps from Molecular Interaction Networks and PubMed Abstracts

(2009) Jiao Li et al.   PLoS Computational Biology

Walking the Interactome for Prioritization of Candidate Disease Genes

(2008) Sebastian Köhler et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Bortezomib With or Without Irinotecan in Relapsed or Refractory Colorectal Cancer: Results From a Randomized Phase II Study

(2008) Peter S. Kozuch et al.   JOURNAL OF CLINICAL ONCOLOGY

Critical role of prostate apoptosis response-4 in determining the sensitivity of pancreatic cancer cells to small-molecule inhibitor-induced apoptosis

(2008) A. S. Azmi et al.   MOLECULAR CANCER THERAPEUTICS