Sensitivity and specificity of phospho-Ser129 α-synuclein monoclonal antibodies

Best Practices for Generating and Using Alpha-Synuclein Pre-Formed Fibrils to Model Parkinson’s Disease in Rodents

(2018) Nicole K. Polinski et al.   Journal of Parkinsons Disease

α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration

(2017) Hisham Abdelmotilib et al.   NEUROBIOLOGY OF DISEASE

Mechanisms underlying extensive Ser129-phosphorylation in α-synuclein aggregates

(2017) Shigeki Arawaka et al.   Acta Neuropathologica Communications

Propagation of pathological α-synuclein in marmoset brain

(2017) Aki Shimozawa et al.   Acta Neuropathologica Communications

α-synuclein transfer through tunneling nanotubes occurs in SH-SY5Y cells and primary brain pericytes from Parkinson’s disease patients

(2017) Birger Victor Dieriks et al.   Scientific Reports

Proaggregant nuclear factor(s) trigger rapid formation of α-synuclein aggregates in apoptotic neurons

(2016) Peizhou Jiang et al.   ACTA NEUROPATHOLOGICA

Activation of tyrosine kinase c-Abl contributes to α-synuclein–induced neurodegeneration

(2016) Saurav Brahmachari et al.   JOURNAL OF CLINICAL INVESTIGATION

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein

(2016) Marcus D Tuttle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein

(2016) Marcus D Tuttle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Implication of Alpha-Synuclein Phosphorylation at S129 in Synucleinopathies: What Have We Learned in the Last Decade?

(2016) Abid Oueslati   Journal of Parkinsons Disease

Novel antibodies to phosphorylated α-synuclein serine 129 and NFL serine 473 demonstrate the close molecular homology of these epitopes

(2016) Nicola J. Rutherford et al.   Acta Neuropathologica Communications

Steady-state and time-resolved Thioflavin-T fluorescence can report on morphological differences in amyloid fibrils formed by Aβ(1-40) and Aβ(1-42)

(2015) David J. Lindberg et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration

(2015) Katrina L. Paumier et al.   NEUROBIOLOGY OF DISEASE

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

(2015) Stanley B. Prusiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metformin lowers Ser-129 phosphorylated α-synuclein levels via mTOR-dependent protein phosphatase 2A activation

(2014) B I Pérez-Revuelta et al.   Cell Death & Disease

Pathological alpha-synuclein propagates through neural networks

(2014) Masami Masuda-Suzukake et al.   Acta Neuropathologica Communications

Biochemical Increase in Phosphorylated Alpha-Synuclein Precedes Histopathology of Lewy-Type Synucleinopathies

(2012) Lih-Fen Lue et al.   BRAIN PATHOLOGY

Changes in properties of serine 129 phosphorylated α-synuclein with progression of Lewy-type histopathology in human brains

(2012) Douglas G. Walker et al.   EXPERIMENTAL NEUROLOGY

Pathological  -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

(2012) K. C. Luk et al.   SCIENCE

Interaction of Thioflavin T with Amyloid Fibrils: Stoichiometry and Affinity of Dye Binding, Absorption Spectra of Bound Dye

(2011) Anna I. Sulatskaya et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Improved Immunodetection of Endogenous α-Synuclein

(2011) Byung Rho Lee et al.   PLoS One

Characterization of kinases involved in the phosphorylation of aggregated α-synuclein

(2010) Elisa A. Waxman et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The progression of pathology in longitudinally followed patients with Parkinson’s disease

(2008) Glenda Halliday et al.   ACTA NEUROPATHOLOGICA

A critical evaluation of the Braak staging scheme for Parkinson's disease

(2008) Robert E. Burke et al.   ANNALS OF NEUROLOGY

In vitro high affinity α-synuclein binding sites for the amyloid imaging agent PIB are not matched by binding to Lewy bodies in postmortem human brain

(2008) Liang Ye et al.   JOURNAL OF NEUROCHEMISTRY