Proaggregant nuclear factor(s) trigger rapid formation of α-synuclein aggregates in apoptotic neurons

Spontaneous Aggregation and Altered Intracellular Distribution of Endogenous α-Synuclein During Neuronal Apoptosis

(2017) Antonietta Gentile et al.   JOURNAL OF ALZHEIMERS DISEASE

Targeting α-synuclein oligomers by protein-fragment complementation for drug discovery in synucleinopathies

(2015) Simon Moussaud et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Extracellular ATP induces intracellular alpha-synuclein accumulation via P2X1 receptor-mediated lysosomal dysfunction

(2015) Ming Gan et al.   NEUROBIOLOGY OF AGING

Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases

(2014) Jing L Guo et al.   NATURE MEDICINE

Prion-like spreading of pathological α-synuclein in brain

(2013) Masami Masuda-Suzukake et al.   BRAIN

The immune system and aging: a review

(2013) Camil Castelo-Branco et al.   GYNECOLOGICAL ENDOCRINOLOGY

The nuclear accumulation of alpha-synuclein is mediated by importin alpha and promotes neurotoxicity by accelerating the cell cycle

(2013) Kai-Li Ma et al.   NEUROPHARMACOLOGY

The prion hypothesis in Parkinson's disease: Braak to the future

(2013) Naomi P Visanji et al.   Acta Neuropathologica Communications

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

(2012) Kelvin C. Luk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Exosomal cell-to-cell transmission of alpha synuclein oligomers

(2012) Karin M Danzer et al.   Molecular Neurodegeneration

Adenosine monophosphate-activated protein kinase overactivation leads to accumulation of α-synuclein oligomers and decrease of neurites

(2012) Peizhou Jiang et al.   NEUROBIOLOGY OF AGING

Pathological  -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

(2012) K. C. Luk et al.   SCIENCE

The innate immune system and the clearance of apoptotic cells

(2011) Andrew Devitt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

ER stress response plays an important role in aggregation of α-synuclein

(2011) Peizhou Jiang et al.   Molecular Neurodegeneration

Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death

(2011) Laura A. Volpicelli-Daley et al.   NEURON

Age-Dependent Deterioration of Nuclear Pore Complexes Causes a Loss of Nuclear Integrity in Postmitotic Cells

(2009) Maximiliano A. D'Angelo et al.   CELL

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of  -synuclein

(2009) P. Desplats et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic profiling of phosphoproteins and glycoproteins responsive to wild-type alpha-synuclein accumulation and aggregation

(2008) Jayanarayan Kulathingal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Using leucine zipper to facilitate α-synuclein assembly

(2008) Peizhou Jiang et al.   FASEB JOURNAL

Aggregates Assembled From Overexpression of Wild-Type α-Synuclein are not Toxic to Human Neuronal Cells

(2008) Li-wen Ko et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

(2008) Jia-Yi Li et al.   NATURE MEDICINE

Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease

(2008) Jeffrey H Kordower et al.   NATURE MEDICINE