Anti-Apoptosis and Anti-Fibrosis Effects of Eriobotrya Japonica in Spontaneously Hypertensive Rat Hearts

Platycodon grandiflorum (PG) reverses angiotensin II-induced apoptosis by repressing IGF-IIR expression

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Bioactive triterpenoids from the leaves of Eriobotrya japonica as the natural PDE4 inhibitors

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Cardioprotection induced in a mouse model of neuropathic pain via anterior nucleus of paraventricular thalamus

(2017) Yi-Fen Cheng et al.   Nature Communications

Plasminogen Activator Inhibitor-1 Protects Mice Against Cardiac Fibrosis by Inhibiting Urokinase-type Plasminogen Activator-mediated Plasminogen Activation

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Traditional Chinese medicine suppresses left ventricular hypertrophy by targeting extracellular signal-regulated kinases signaling pathway in spontaneously hypertensive rats

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Mechanisms of Chinese Medicine Xinmailong’s protection against heart failure in pressure-overloaded mice and cultured cardiomyocytes

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Cardiac Remodeling: Concepts, Clinical Impact, Pathophysiological Mechanisms and Pharmacologic Treatment

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Protective effect of Co-enzyme Q10 On doxorubicin-induced cardiomyopathy of rat hearts

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Alpinate Oxyphyllae Fructus Inhibits IGFII-Related Signaling Pathway to Attenuate Ang II-Induced Pathological Hypertrophy in H9c2 Cardiomyoblasts

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Doxorubicin attenuates CHIP-guarded HSF1 nuclear translocation and protein stability to trigger IGF-IIR-dependent cardiomyocyte death

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Anti-inflammatory and antioxidant properties of Eriobotrya japonica leaves extracts

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PDCD5 protects against cardiac remodeling by regulating autophagy and apoptosis

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Getting to the Heart of the Matter

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Loquat leaf extract enhances myogenic differentiation, improves muscle function and attenuates muscle loss in aged rats

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Circulating Biomarkers of Myocardial Fibrosis

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Loquat (Eriobotrya japonica) extract prevents dexamethasone-induced muscle atrophy by inhibiting the muscle degradation pathway in Sprague Dawley rats

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Integrating traditional Chinese medicine into Western cardiovascular medicine: an evidence-based approach

(2015) Xingjiang Xiong   Nature Reviews Cardiology

The Cardioprotection of the Insulin-Mediated PI3K/Akt/mTOR Signaling Pathway

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Protective effect of Danggui (Radix Angelicae Sinensis) on angiotensin II-induced apoptosis in H9c2 cardiomyoblast cells

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Tadalafil Prevents Acute Heart Failure with Reduced Ejection Fraction in Mice

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ANG II promotes IGF-IIR expression and cardiomyocyte apoptosis by inhibiting HSF1 via JNK activation and SIRT1 degradation

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Herbal Medicines for Cardiovascular Diseases

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Always cleave up your mess: targeting collagen degradation to treat tissue fibrosis

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High Blood Pressure: The Leading Global Burden of Disease Risk Factor and the Need for Worldwide Prevention Programs

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Evidence-Based Chinese Medicine for Hypertension

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Chinese herbal formulas for treating hypertension in traditional Chinese medicine: perspective of modern science

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Probiotic-fermented purple sweet potato yogurt activates compensatory IGF-IR/PI3K/Akt survival pathways and attenuates cardiac apoptosis in the hearts of spontaneously hypertensive rats

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Dung-shen (Codonopsis pilosula) attenuated the cardiac-impaired insulin-like growth factor II receptor pathway on myocardial cells

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Allicin protects against myocardial apoptosis and fibrosis in streptozotocin-induced diabetic rats

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Histone acetylation is essential for ANG-II-induced IGF-IIR gene expression in H9c2 cardiomyoblast cells and pathologically hypertensive rat heart

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Effect of the plasminogen-plasmin system on hypertensive renal and cardiac damage

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Anti-inflammatory and antinociceptive properties of the leaves of Eriobotrya japonica

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IGF-II/mannose 6-phosphate receptor activation induces metalloproteinase-9 matrix activity and increases plasminogen activator expression in H9c2 cardiomyoblast cells

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