Always cleave up your mess: targeting collagen degradation to treat tissue fibrosis

Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis

(2013) Yong Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Update in Diffuse Parenchymal Lung Disease 2011

(2012) Tracy R. Luckhardt et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis

(2012) Isis E Fernandez et al.   LANCET

Interstitial lung disease in connective tissue disorders

(2012) Aryeh Fischer et al.   LANCET

Experimental diabetic nephropathy is accelerated in matrix metalloproteinase-2 knockout mice

(2012) Yoshimi Takamiya et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis

(2011) Cory M. Yamashita et al.   AMERICAN JOURNAL OF PATHOLOGY

Hypoxia-inducible factor-1α mediates TGF-β-induced PAI-1 production in alveolar macrophages in pulmonary fibrosis

(2011) Manabu Ueno et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

(2011) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Role of Urokinase Plasminogen Activator Receptor–Associated Protein in Mouse Lung

(2011) Michael M. Bundesmann et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Therapeutic Value of Small Molecule Inhibitor to Plasminogen Activator Inhibitor–1 for Lung Fibrosis

(2011) Wen-Tan Huang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The vitronectin-binding function of PAI-1 exacerbates lung fibrosis in mice

(2011) A. J. Courey et al.   BLOOD

Parenchymal trafficking of pleural mesothelial cells in idiopathic pulmonary fibrosis

(2011) K. K. Mubarak et al.   EUROPEAN RESPIRATORY JOURNAL

The Non-phagocytic Route of Collagen Uptake

(2011) Daniel H. Madsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44

(2011) Yuejuan Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Idiopathic pulmonary fibrosis

(2011) Talmadge E King et al.   LANCET

Collagen I matrix turnover is regulated by fibronectin polymerization

(2010) Feng Shi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Role of lysyl oxidase in myocardial fibrosis: from basic science to clinical aspects

(2010) Begoña López et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Molecular and structural mapping of collagen fibril interactions

(2010) J. P. R. O. Orgel et al.   CONNECTIVE TISSUE RESEARCH

Loss of Matrix Metalloproteinase-2 Amplifies Murine Toxin-Induced Liver Fibrosis by Upregulating Collagen I Expression

(2010) Brian D. Radbill et al.   DIGESTIVE DISEASES AND SCIENCES

Deficiency of matrix metalloproteinase-13 increases inflammation after acute lung injury

(2010) Anita I. Sen et al.   EXPERIMENTAL LUNG RESEARCH

Loss of Matrix Metalloproteinase-13 Attenuates Murine Radiation-Induced Pulmonary Fibrosis

(2010) Paul Flechsig et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

(2010) Fei Liu et al.   JOURNAL OF CELL BIOLOGY

Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

(2010) Vivian Barry-Hamilton et al.   NATURE MEDICINE

Resistance to Bleomycin-Induced Lung Fibrosis in MMP-8 Deficient Mice Is Mediated by Interleukin-10

(2010) Emilio García-Prieto et al.   PLoS One

The pathogenesis of idiopathic pulmonary fibrosis

(2010) William R. Coward et al.   Therapeutic Advances in Respiratory Disease

Pleural mesothelial cell transformation into myofibroblasts and haptotactic migration in response to TGF-β1 in vitro

(2009) Najmunnisa Nasreen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

New Mechanisms of Pulmonary Fibrosis

(2009) Robert M. Strieter et al.   CHEST

Membrane type-1 matrix metalloproteinase activity is regulated by the endocytic collagen receptor Endo180

(2009) G. Messaritou et al.   JOURNAL OF CELL SCIENCE

Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages

(2009) Kamran Atabai et al.   JOURNAL OF CLINICAL INVESTIGATION

Differences in collagen architecture between keloid, hypertrophic scar, normotrophic scar, and normal skin: An objective histopathological analysis

(2009) Pauline D. H. M. Verhaegen et al.   WOUND REPAIR AND REGENERATION

Treatment of Idiopathic Pulmonary Fibrosis with Etanercept

(2008) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Matrix Metalloproteinase-14 Deficiency in Bone Marrow–Derived Cells Promotes Collagen Accumulation in Mouse Atherosclerotic Plaques

(2008) Fabrice Schneider et al.   CIRCULATION

Collagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleators

(2008) Karl E Kadler et al.   CURRENT OPINION IN CELL BIOLOGY

Candidate Cell and Matrix Interaction Domains on the Collagen Fibril, the Predominant Protein of Vertebrates

(2008) Shawn M. Sweeney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tissue plasminogen activator (t-PA) promotes neutrophil degranulation and MMP-9 release

(2008) Eloy Cuadrado et al.   JOURNAL OF LEUKOCYTE BIOLOGY

An Essential Role for Fibronectin Extra Type III Domain A in Pulmonary Fibrosis

(2007) Andrés F. Muro et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE