Article
Integrative & Complementary Medicine
Jun-Yuan Zhang, Qian-Qian Chen, Jia Li, Lei Zhang, Lian-Wen Qi
Summary: Neuraminidase is a widely distributed enzyme found in animals and microorganisms, predominantly in cell membrane, cytoplasmic vesicles, and lysosomes. It plays a key role in recognizing and removing sialic acid glycosidic bonds. Among the four types of neuraminidases, Neu1 is the most abundant and has been implicated in various diseases, especially cardiovascular diseases.
AMERICAN JOURNAL OF CHINESE MEDICINE
(2021)
Review
Cardiac & Cardiovascular Systems
Lucinda Villaescusa, Cristina Zaragoza, Francisco Zaragoza, Juan Tamargo
Summary: Traditional use of herbal medicines (HMs) for the prophylaxis/treatment of cardiovascular diseases (CVDs) lacks scientific evidence supporting their efficacy and safety. Many patients combine HMs with prescribed cardiovascular medications without informing their doctors, who also rarely inquire about HMs use. There are concerns regarding the quality control, active constituents, and mechanisms of action of HMs.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Fisheries
Weini Zhang, Jinpeng Zhao, Yufang Ma, Jian Li, Xinhua Chen
Summary: The increasing demand for fish consumption has led to the rapid growth of fish aquaculture. However, the use of antibiotics and chemicals for disease prevention and control in fish farming is restricted due to issues such as drug residues, pathogen resistance, and environmental pollution. Herbs and their extracts have emerged as promising alternatives because they are effective, safe, environmentally friendly, and have lower drug resistance. This paper comprehensively summarizes the research progress of herbal ingredients used for disease prevention and control in fish, particularly focusing on their mechanisms of action, and highlights the potential application of herbal medicines in fish aquaculture.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Review
Chemistry, Physical
Ya-Li Zhang, Ya-Lei Wang, Ke Yan, Qi-Qi Deng, Fang-Zhou Li, Xing-Jie Liang, Qian Hua
Summary: Through the study of nanomaterials in Chinese herbal medicines (CHMs), the material basis of CHMs can be understood, and their applications in specific disease treatment can be explored. These CHM-derived nanostructures include extracted CHMs, polymer nanoparticles, liposomes, micelles, and nanofibers. The therapeutic efficacy of CHMs can be effectively studied using these nanostructures, but there are still challenges and opportunities in their development.
NANOSCALE HORIZONS
(2023)
Review
Pharmacology & Pharmacy
Minghui Li, Cheng Rao, Xiaoqian Ye, Mei Wang, Boyuan Yang, Chengxiao Wang, Liqun Guo, Yin Xiong, Xiuming Cui
Summary: Chinese herbal medicines (CHMs) have a wide range of bioactive components, making them an important source for new drug discovery. However, the current process to obtain these components often involves the use of large amounts of toxic and non-biodegradable organic solvents. Natural deep eutectic solvents (NADES), composed of plant-based metabolites, are eco-friendly alternatives to traditional solvents. They have been used as extraction solvents, media, and drug delivery agents in CHMs, and have contributed to understanding the traditional processing theory of CHMs.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Plant Sciences
Jose M. Prieto-Garcia, Louise Graham, Osamah Alkhabbaz, Andre L. D. A. Mazzari
Summary: Herb-drug interactions are a crucial consideration in healthcare interventions, particularly for patients with cardiovascular risk factors. This study conducted a scoping review to identify potential herb-drug interactions in the treatment of hyperlipidemia and hypertension. The findings highlighted the need for further clinical research to determine the interaction risks of certain drugs in long-term treatments.
Article
Plant Sciences
Filipe Fernandes, M. Fatima Barroso, Angela De Simone, Eliska Emrikova, Monica Dias-Teixeira, Jose Paulo Pereira, Jakub Chlebek, Virginia Cruz Fernandes, Francisca Rodrigues, Vincenza Andrisano, Cristina Delerue-Matos, Clara Grosso
Summary: This study aimed to explore the neuroprotective potential of seven traditional medicinal plants and evaluate their safety regarding pesticides residues. The results showed that these plant extracts were able to scavenge free radicals, inhibit glycogen synthase kinase-3 beta, and exhibited low cytotoxicity to brain cell lines.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Review
Chemistry, Multidisciplinary
Mayang Kusuma Dewi, Anis Yohana Chaerunisaa, Muhaimin Muhaimin, I. Made Joni
Summary: Phytochemicals or secondary metabolites are substances produced by plants that have shown various biological activities, providing a scientific basis for the use of herbs in traditional medicine. Although herbal medicines are considered to be safe and cost-effective, they have disadvantages such as low solubility, stability, and bioavailability. In recent years, nanotechnology-based herbal drug formulations have gained attention for their enhanced activity and potential in overcoming these issues.
Review
Engineering, Chemical
Pavitra Murthy, Nur Adania Shaibie, Chooi Ling Lim, Anna Pick Kiong Ling, Soi Moi Chye, Rhun Yian Koh
Summary: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease characterized by interstitial lung scarring. Herbal medicines, such as Traditional Chinese Medicine (TCM), have shown promise as alternative treatments for IPF due to their natural properties and therapeutic effects.
Article
Integrative & Complementary Medicine
Qinge Ma, Chong-Zhi Wang, Wamtinga R. Sawadogo, Zhao-Xiang Bian, Chun-Su Yuan
Summary: Constipation is a common medical condition that affects patients' quality of life and healthcare systems worldwide. Rhubarb, senna leaf, and aloe are frequently used herbal medications for relieving constipation. The main active components in these herbs are anthraquinones, especially the dianthrone compounds, which have significant effects in promoting gastrointestinal motility and relieving constipation.
AMERICAN JOURNAL OF CHINESE MEDICINE
(2022)
Review
Pharmacology & Pharmacy
Luxia Song, Jie Zhang, Runmin Lai, Qiuyi Li, Jianqing Ju, Hao Xu
Summary: Atherosclerosis is a complex chronic disease involving oxidative stress and dysfunction of the endothelium. Chinese herbal medicines and traditional Chinese medicine have shown potential in regulating oxidative stress and treating atherosclerosis-related diseases. Further research is needed to explore new drugs targeting diseases associated with oxidative stress.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Plant Sciences
Abinash Choudhury, Preet Amol Singh, Neha Bajwa, Subhransu Dash, Preeti Bisht
Summary: The use of herbal medicines is increasing worldwide for the prevention, treatment, and prophylaxis of various ailments due to their perceived safety compared to allopathic treatments. However, there have been investigations showing the toxicity and adverse drug reactions of certain herbal formulations and botanicals if not used wisely. This study aims to address pharmacovigilance modeling for herbal medications and analyze the current state of pharmacovigilance at national and international levels.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Review
Chemistry, Medicinal
Motahareh Boozari, Hossein Hosseinzadeh
Summary: This review discusses the preventive effects of herbal medicine and natural products against contrast-induced nephropathy. It emphasizes the need for more practical and completed clinical trials to investigate the clinical benefits of natural products for the prevention and/or treatment of CIN.
PHYTOTHERAPY RESEARCH
(2021)
Review
Integrative & Complementary Medicine
Mei Wang, Pei-Fen Yao, Peng-Yue Sun, Wen Liang, Xiao-Jia Chen
Summary: This article mainly discusses the quality requirements and regulations for Chinese herbal medicines to enter the European Union market. By comparing the quality control and registration routes of herbal medicines in China and Europe, it provides a reference for the development of Chinese herbal medicines in the EU market.
Review
Pharmacology & Pharmacy
Yun Zhang, Xing Wang, He Zhang, Hongmei Tang, Hang Hu, Songping Wang, Vincent Kam Wai Wong, Yuying Li, Jun Deng
Summary: Asthma is a global health issue affecting over 300 million people worldwide, and treatment options include using different agents targeting different pathways. Autophagy modulation may offer new therapeutic approaches for asthma.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Physiology
Andre C. Michalski, Arthur S. Ferreira, Adrian W. Midgley, Victor A. B. Costa, Guilherme F. Fonseca, Nadia S. L. da Silva, Juliana Borges, Sandra A. Billinger, Felipe A. Cunha
Summary: This study investigated the effects of a single bout of mixed circuit training (MCT) on arterial stiffness in patients with chronic stroke, and assessed the between-day reproducibility of arterial stiffness measurements. The results showed that MCT significantly reduced arterial stiffness in patients with chronic stroke and had moderate-to-high reproducibility.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Rehabilitation
Flavia A. F. Oliveira, Camilla P. Martins, Laura A. S. de Oliveira, Erika C. Rodrigues, Arthur S. Ferreira, Thiago Lemos
Summary: This study investigated the optimization properties of postural stability in poststroke individuals using a direct search algorithm. The results showed that the asymmetric weight-bearing poststroke group had a faster convergence rate towards the local minimum of postural sway, while the low balance capability group had smaller values for average local minima and global minimum of postural sway coordinates. Significant correlations were found between the Berg Balance Scale and the local minima and global minimum.
TOPICS IN STROKE REHABILITATION
(2023)
Article
Orthopedics
Luciana Crepaldi Lunkes, Milton Apolinario Dias Neto, Lavinia Fernandes Barra, Livia Resende de Castro, Arthur Sa Ferreira, Ney Meziat-Filho
Summary: This study aims to investigate the effectiveness of education to keep the abdomen relaxed versus contracted during Pilates exercises in patients with primary chronic low back pain. The study will be conducted as a two-group randomised controlled trial with a total of 152 participants. The findings will help in clinical decision-making and understanding the importance of abdominal contraction in the effectiveness of the Pilates method for this population.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Physiology
Guilherme F. Fonseca, Andre C. Michalski, Arthur S. Ferreira, Victor A. B. Costa, Renato Massaferri, Paulo Farinatti, Felipe A. Cunha
Summary: This study assessed the reproducibility of postexercise hypotension (PEH) detection after two bouts of mixed circuit training (MCT) in chronic stroke patients. The most reliable approach for determining PEH was to compare the postexercise blood pressure values with a control session, and the proportion of PEH responders was not affected by the cut-off values applied.
CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING
(2023)
Article
Geriatrics & Gerontology
Sabrina de Oliveira Silva, Jessica Bandeira Barbosa, Thiago Lemos, Laura Alice Santos Oliveira, Arthur de Sa Ferreira
Summary: Falls in hospitalized older adults are a concern, but the validity and agreement of fall risk assessment methods and factors associated with falls have not been well investigated.
Correction
Orthopedics
Luciana Crepaldi Lunkes, Milton Apolinario Dias Neto, Lavinia Fernandes Barra, Livia Resende de Castro, Arthur Sa Ferreira, Ney Meziat-Filho
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Clinical Neurology
Talita P. Pinto, Jacqueline C. Inacio, Erivelton de Aguiar, Arthur S. Ferreira, Felipe Kenji Sudo, Fernanda Tovar-Moll, Erika C. Rodrigues
Summary: The study aimed to investigate the efficacy, safety, and feasibility of a single session of bihemispheric prefrontal tDCS on cardiac autonomic regulation and mood of COVID-19 inpatients. The results showed a significant effect of tDCS on cardiac autonomic regulation, with increased oxygen saturation in the active group. However, no significant differences were observed in mood and adverse effects. Therefore, a single prefrontal tDCS session is safe and effective in modulating cardiac autonomic regulation in acute COVID-19 inpatients.
Article
Orthopedics
Ana Paula dos Santos Bento, Ney Meziat, Arthur de Sa Ferreira, Ana Paula Cassetta, Renato Santos de Almeida
Summary: This study aimed to describe the main polysomnographic findings in patients with chronic musculoskeletal pain and estimate the association between sleep quality, polysomnography variables and chronic musculoskeletal pain. The study found that most patients had nocturnal awakenings, sleep apnea episodes, and prolonged REM sleep phase latency. There was a strong correlation between sleep quality and central sensitization signs.
BRAZILIAN JOURNAL OF PHYSICAL THERAPY
(2023)
Article
Rehabilitation
Rafael Alexandre de Oliveira Deucher, Luis Felipe da Fonseca Reis, Jannis Vasileios Papathanasiou, Beatriz Luiza Pinheiro Alves Azevedo, Jessica Gabriela Messias Oliveira, Matheus Mello da Silva, Rayanne Costa de Sales, Beatriz Pereira dos Santos, Arthur de Sa Ferreira, Agnaldo Jose Lopes
Summary: This study aimed to create a predictive equation for peak oxygen uptake (VO2peak) obtained by simple sampling technology in women with rheumatoid arthritis-associated interstitial lung disease (RA-ILD). The results showed that VO2peak was correlated with various factors such as age, disease activity index, and pulmonary function testing. Forward regression analysis identified resonance frequency, diffusing capacity for carbon monoxide, and age as significant predictors of VO2peak variability.
PHYSIOTHERAPY RESEARCH INTERNATIONAL
(2023)
Article
Rehabilitation
Camilo Zumbi Rafagnin, Arthur de Sa Ferreira, Gustavo Felicio Telles, Thiago Lemos de Carvalho, Dangelo Jose de Andrade Alexandre, Leandro Alberto Calazans Nogueira
Summary: This study aimed to investigate the relationship between dorsiflexion range of motion and the Y-Balance Test in elite futsal players. The results showed that dorsiflexion range of motion was significantly correlated with the anterior and posteromedial components, as well as the composite score of the Y-Balance Test. Dorsiflexion range of motion explained 7% to 24% of the variation in the distances reached in the Y-Balance Test.
PHYSIOTHERAPY RESEARCH INTERNATIONAL
(2023)
Article
Respiratory System
Vanessa Joaquim Ribeiro Moco, Aline Almeida Gulart, Agnaldo Jose Lopes, Arthur de Sa Ferreira, Luis Felipe da Fonseca Reis
Summary: Home exercises with minimal resources can improve activities of daily living, reduce dyspnea, and enhance health status and quality of life in individuals with COPD.
COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2023)
Article
Public, Environmental & Occupational Health
Cynthia Mara Zilli Casagrande, Jean Paulo Farias, Ney Meziat-Filho, Leandro Alberto Calazans Nogueira, Arthur Sa Ferreira
Summary: Better work ability is associated with lower levels of occupational stress and physical activity, but higher levels of leisure activities and physical exercises. Sociodemographic factors and ergonomics organization have a smaller role in determining the work ability of professional drivers.
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Orthopedics
Luciana Alves Custodio, Yara Andrade Marques, Aline Martins de Toledo, Arthur de Sa Ferreira, Maurits van Tulder, Everton Nunes da Silva, Rodrigo Luiz Carregaro
Summary: This study investigated the care pathway and interventions for individuals with non-specific spinal disorders in the Federal District of Brazil. The results showed that the emergency department was the most commonly accessed setting, with a majority of individuals undergoing imaging tests and receiving drug prescriptions. However, few participants received exercise prescriptions and only half were referred to physical therapists. Women were more likely to first access the emergency department, and increasing age was associated with a greater chance of first accessing outpatient clinics.
BRAZILIAN JOURNAL OF PHYSICAL THERAPY
(2023)
Article
Rehabilitation
Juliana Valentim Bittencourt, Eduardo Gallas Leivas, Arthur de Sa Ferreira, Leandro Alberto Calazans Nogueira
Summary: This study evaluated the diagnostic accuracy of the painDETECT questionnaire in detecting the impairment of conditioned pain modulation in patients with musculoskeletal pain. The results showed that the painDETECT questionnaire had high specificity and negative predictive value in screening for impairment of conditioned pain modulation, making it useful for ruling out relevant cases.
ARCHIVES OF PHYSIOTHERAPY
(2023)
Article
Rehabilitation
Joao Eduardo de Azevedo Vieira, Arthur de Sa Ferreira, Laura Braga Monnerat, Mariana Soares da Cal, Angelo Thomaz Abalada Ghetti, Thiago Thomaz Mafort, Agnaldo Jose Lopes
Summary: This study built prediction models for the Post-COVID-19 Functional Status (PCFS) scale using sociodemographic data, clinical findings, lung function, and muscle strength. The results showed that worse general fatigue and handgrip strength were associated with more severe physical function impairments in patients with post-COVID-19 syndrome. Additionally, a history of prior hospitalization resulted in worse physical function. Prediction models incorporating objective measures can better assess the physical function of these patients and aid in the selection of candidates for a physical reconditioning program.
JOURNAL OF BODYWORK AND MOVEMENT THERAPIES
(2024)
