ALUminating the Path of Atherosclerosis Progression: Chaos Theory Suggests a Role for Alu Repeats in the Development of Atherosclerotic Vascular Disease

Who Needs This Junk, or Genomic Dark Matter

(2018) O. I. Podgornaya et al.   BIOCHEMISTRY-MOSCOW

Metazoan MicroRNAs

(2018) David P. Bartel   CELL

Mammalian transposable elements and their impacts on genome evolution

(2018) Roy N. Platt et al.   CHROMOSOME RESEARCH

PIWI family emerging as a decisive factor of cell fate: An overview

(2017) Murugavel Ponnusamy et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Retrotransposon expression and incorporation of cloned human and mouse retroelements in human spermatozoa

(2017) Leandros Lazaros et al.   FERTILITY AND STERILITY

The over expression of long non-coding RNA ANRIL promotes epithelial-mesenchymal transition by activating the ATM-E2F1 signaling pathway in pancreatic cancer: An in vivo and in vitro study

(2017) Shi Chen et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Potential Role of Long Non-Coding RNA ANRIL in Pediatric Medulloblastoma Through Promotion on Proliferation and Migration by Targeting miR-323

(2017) Hong Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Genetic Susceptibility Contributing to Periodontal and Cardiovascular Disease

(2017) G. Aarabi et al.   JOURNAL OF DENTAL RESEARCH

Polymorphisms of MTHFR , eNOS , ACE , AGT , ApoE , PON1 , PDE4D , and Ischemic Stroke: Meta-Analysis

(2017) Loo Keat Wei et al.   Journal of Stroke & Cerebrovascular Diseases

Gene regulation of mammalian long non-coding RNA

(2017) Heeyoun Bunch   MOLECULAR GENETICS AND GENOMICS

Alu RNA accumulation induces epithelial-to-mesenchymal transition by modulating miR-566 and is associated with cancer progression

(2017) F Di Ruocco et al.   ONCOGENE

Long Noncoding RNA ANRIL Promotes Cervical Cancer Development By Acting as a Sponge of miR-186

(2017) Jun-Jun Zhang et al.   ONCOLOGY RESEARCH

Structural variants caused byAluinsertions are associated with risks for many human diseases

(2017) Lindsay M. Payer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ALU ternative Regulation for Gene Expression

(2017) Ling-Ling Chen et al.   TRENDS IN CELL BIOLOGY

Polymorphisms of MTHFR , eNOS , ACE , AGT , ApoE , PON1 , PDE4D , and Ischemic Stroke: Meta-Analysis

(2017) Loo Keat Wei et al.   Journal of Stroke & Cerebrovascular Diseases

Current Research on Non-Coding Ribonucleic Acid (RNA)

(2017) Jing Wang et al.   Genes

Circular RNAs (circRNAs) in Health and Disease

(2017) et al.   Genes

Nonlinear dynamics of early atherosclerotic plaque formation may determine the efficacy of high density lipoproteins (HDL) in plaque regression

(2017) Alexander D. Chalmers et al.   PLoS One

Complex multifractal nature in Mycobacterium tuberculosis genome

(2017) Saurav Mandal et al.   Scientific Reports

Silencing of CD40 in vivo reduces progression of experimental atherogenesis through an NF-κB/miR-125b axis and reveals new potential mediators in the pathogenesis of atherosclerosis

(2016) Miguel Hueso et al.   ATHEROSCLEROSIS

MicroRNA Regulation of Atherosclerosis

(2016) Mark W. Feinberg et al.   CIRCULATION RESEARCH

Genetics of Coronary Artery Disease

(2016) Ruth McPherson et al.   CIRCULATION RESEARCH

The 9p21 Locus and its Potential Role in Atherosclerosis Susceptibility; Molecular Mechanisms and Clinical Implications

(2016) Amir Tajbakhsh et al.   CURRENT PHARMACEUTICAL DESIGN

The impact of genome‐wide association studies on the pathophysiology and therapy of cardiovascular disease

(2016) Thorsten Kessler et al.   EMBO Molecular Medicine

Alu repeats as transcriptional regulatory platforms in macrophage responses toM. tuberculosisinfection

(2016) Manuella Bouttier et al.   NUCLEIC ACIDS RESEARCH

Alu methylation serves as a biomarker for non-invasive diagnosis of glioma

(2016) Jian Chen et al.   Oncotarget

Enrichment analysis of Alu elements with different spatial chromatin proximity in the human genome

(2016) Zhuoya Gu et al.   Protein & Cell

Alu-miRNA interactions modulate transcript isoform diversity in stress response and reveal signatures of positive selection

(2016) Rajesh Pandey et al.   Scientific Reports

A novel fractal approach for predicting G-protein–coupled receptors and their subfamilies with support vector machines

(2015) Guoping Nie et al.   BIO-MEDICAL MATERIALS AND ENGINEERING

The role of Alu elements in the cis-regulation of RNA processing

(2015) Chammiran Daniel et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Transposable Elements in Cancer and Other Human Diseases

(2015) Benoit Chenais   CURRENT CANCER DRUG TARGETS

Blood flow modulation of vascular dynamics

(2015) Juhyun Lee et al.   CURRENT OPINION IN LIPIDOLOGY

Regulatory roles of Alu transcript on gene expression

(2015) Li Zhang et al.   EXPERIMENTAL CELL RESEARCH

Chronic Kidney Disease is associated with an increase of Intimal Dendritic cells in a comparative autopsy study

(2015) Miguel Hueso et al.   Journal of Inflammation-London

Functional genomics of the CDKN2A/B locus in cardiovascular and metabolic disease: what have we learned from GWASs?

(2015) Sarah Anissa Hannou et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

miRNAs in atherosclerotic plaque initiation, progression, and rupture

(2015) Ioannis Andreou et al.   TRENDS IN MOLECULAR MEDICINE

Regulating Pol III transcription to change Pol II transcriptome

(2015) Kenji Ichiyanagi   CELL CYCLE

Transposable elements in eukaryotic genomes: epigenetic regulation by the host and functionalization for the host.

(2015) Kenji Ichiyanagi   GENES & GENETIC SYSTEMS

MicroRNA-125b is involved in atherosclerosis obliterans in vitro by targeting podocalyxin

(2015) XIAOBING LI et al.   Molecular Medicine Reports

The relationship between diastolic blood pressure and coronary artery calcification is dependent on single nucleotide polymorphisms on chromosome 9p21.3

(2014) Daniel S Kim et al.   BMC Medical Genetics

The association of 9p21-3 locus with coronary atherosclerosis: a systematic review and meta-analysis

(2014) Muhammad S Munir et al.   BMC Medical Genetics

ANRIL inhibits p15INK4b through the TGFβ1 signaling pathway in human esophageal squamous cell carcinoma

(2014) Deyu Chen et al.   CELLULAR IMMUNOLOGY

Noncoding RNAs and Atherosclerosis

(2014) Binod Aryal et al.   Current Atherosclerosis Reports

Building Specific Signals from Frequency Chaos Game and Revealing Periodicities Using a Smoothed Fourier Analysis

(2014) Imen Messaoudi et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

Association between the ACE I/D polymorphism and risk of ischemic stroke: An updated meta-analysis of 47,026 subjects from 105 case–control studies

(2014) Jiangyang Zhao et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

miR-21 attenuates lipopolysaccharide-induced lipid accumulation and inflammatory response: potential role in cerebrovascular disease

(2014) Jun Feng et al.   Lipids in Health and Disease

Identification of RNA polymerase III-transcribed Alu loci by computational screening of RNA-Seq data

(2014) Anastasia Conti et al.   NUCLEIC ACIDS RESEARCH

The LDL-HDL Profile Determines the Risk of Atherosclerosis: A Mathematical Model

(2014) Wenrui Hao et al.   PLoS One

Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism Contributes High Risk for Chronic Kidney Disease in Asian Male with Hypertension–A Meta-Regression Analysis of 98 Observational Studies

(2014) Chin Lin et al.   PLoS One

Aging affects high-density lipoprotein composition and function

(2013) Michael Holzer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

ANRIL/CDKN2B-AS shows two-stage clade-specific evolution and becomes conserved after transposon insertions in simians

(2013) Sha He et al.   BMC EVOLUTIONARY BIOLOGY

Sequence analysis by iterated maps, a review

(2013) J. S. Almeida   BRIEFINGS IN BIOINFORMATICS

miR-661 downregulates both Mdm2 and Mdm4 to activate p53

(2013) Y Hoffman et al.   CELL DEATH AND DIFFERENTIATION

From genotype to phenotype in human atherosclerosis - recent findings

(2013) Lesca M. Holdt et al.   CURRENT OPINION IN LIPIDOLOGY

Functional microRNAs and target sites are created by lineage-specific transposition

(2013) Ryan M. Spengler et al.   HUMAN MOLECULAR GENETICS

Association Between the Chromosome 9p21 Locus and Angiographic Coronary Artery Disease Burden

(2013) Kenneth Chan et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Associations between the insertion/deletion polymorphism of the angiotensin-converting enzyme and susceptibility to aortic aneurysms: A meta-analysis

(2013) Gwan Gyu Song et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

Investigation on series of length of coding and non-coding DNA sequences of bacteria using multifractal detrended cross-correlation analysis

(2013) Cristina Stan et al.   JOURNAL OF THEORETICAL BIOLOGY

Functional regulation of Alu element of human angiotensin-converting enzyme gene in neuron cells

(2013) Shyh-Jong Wu et al.   NEUROBIOLOGY OF AGING

The Influence of Angiotensin Converting Enzyme and Angiotensinogen Gene Polymorphisms on Hypertrophic Cardiomyopathy

(2013) Rong Luo et al.   PLoS One

Alu elements: an intrinsic source of human genome instability

(2013) Catherine Ade et al.   Current Opinion in Virology

Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks

(2013) Lesca M. Holdt et al.   PLoS Genetics

LDL-cholesterol versus HDL-cholesterol in the atherosclerotic plaque: inflammatory resolution versus thrombotic chaos

(2012) Lina Badimon et al.   Annals of the New York Academy of Sciences

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

Mechanical buckling of artery under pulsatile pressure

(2012) Qin Liu et al.   JOURNAL OF BIOMECHANICS

The human genome: a multifractal analysis

(2011) Pedro A Moreno et al.   BMC GENOMICS

From 'JUNK' to Just Unexplored Noncoding Knowledge: the case of transcribed Alus

(2011) R. Pandey et al.   Briefings in Functional Genomics

Genomic Analysis Reveals a Novel Nuclear Factor-κB (NF-κB)-binding Site in Alu-repetitive Elements

(2011) Athina Antonaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A common variant in the CDKN2B gene on chromosome 9p21 protects against coronary artery disease in Americans of African ancestry

(2011) Brian G Kral et al.   JOURNAL OF HUMAN GENETICS

Nonlinear Mechanical Behavior of The Human Common, External, and Internal Carotid Arteries In Vivo

(2011) Alexey V. Kamenskiy et al.   JOURNAL OF SURGICAL RESEARCH

Ventilatory Chaos Is Impaired in Carotid Atherosclerosis

(2011) Laurence Mangin et al.   PLoS One

Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study

(2010) Michael Preuss et al.   Circulation-Cardiovascular Genetics

Association of polymorphisms in 9p21 region with CAD in North Indian population: replication of SNPs identified through GWAS

(2010) J Kumar et al.   CLINICAL GENETICS

A systems biology approach to understanding atherosclerosis

(2010) Stephen A. Ramsey et al.   EMBO Molecular Medicine

The transcript repeat element: the human Alu sequence as a component of gene networks influencing cancer

(2010) Paula Moolhuijzen et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

The Caenorhabditis elegans genome: a multifractal analysis

(2010) P.E. Vlez et al.   GENETICS AND MOLECULAR RESEARCH

The mechanics of atherosclerotic plaque rupture by inclusion/matrix interfacial decohesion

(2010) Chien M. Nguyen et al.   JOURNAL OF BIOMECHANICS

Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice

(2010) Axel Visel et al.   NATURE

Structure and activity of putative intronic miRNA promoters

(2010) A. M. Monteys et al.   RNA

Variation in Transcription Factor Binding Among Humans

(2010) M. Kasowski et al.   SCIENCE

Rupture of Vulnerable Atherosclerotic Plaques: MicroRNAs Conducting the Orchestra?

(2010) Vincent G. Haver et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk

(2010) Christin E. Burd et al.   PLoS Genetics

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Alu-directed transcriptional regulation of some novel miRNAs

(2009) Tong J Gu et al.   BMC GENOMICS

9p21 is a Shared Susceptibility Locus Strongly for Coronary Artery Disease and Weakly for Ischemic Stroke in Chinese Han Population

(2009) Hu Ding et al.   Circulation-Cardiovascular Genetics

Overexpression of Activated Nuclear Factor-κ B in Aorta of Patients With Coronary Atherosclerosis

(2009) Wei Zhang et al.   CLINICAL CARDIOLOGY

Insights from genomic profiling of transcription factors

(2009) Peggy J. Farnham   NATURE REVIEWS GENETICS

The impact of retrotransposons on human genome evolution

(2009) Richard Cordaux et al.   NATURE REVIEWS GENETICS

Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells

(2009) Y Saito et al.   ONCOGENE

Mathematical modelling of atherosclerosis as an inflammatory disease

(2009) N. El Khatib et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Evidence for Co-Evolution between Human MicroRNAs and Alu-Repeats

(2009) Stefan Lehnert et al.   PLoS One

Alu and B1 Repeats Have Been Selectively Retained in the Upstream and Intronic Regions of Genes of Specific Functional Classes

(2009) Aristotelis Tsirigos et al.   PLoS Computational Biology

Four SNPS on Chromosome 9p21 Confer Risk to Premature, Familial CAD and MI in an American Caucasian Population (GeneQuest)

(2008) K. G. Abdullah et al.   ANNALS OF HUMAN GENETICS

Human Pol II promoter recognition based on primary sequences and free energy of dinucleotides

(2008) Jian-Yi Yang et al.   BMC BIOINFORMATICS

Role of microRNAs in vascular diseases, inflammation, and angiogenesis

(2008) C. Urbich et al.   CARDIOVASCULAR RESEARCH

Interferon gamma: A master regulator of atherosclerosis

(2008) James E. McLaren et al.   CYTOKINE & GROWTH FACTOR REVIEWS

LINE-1 ORF1 protein enhances Alu SINE retrotransposition

(2008) Nicholas Wallace et al.   GENE

Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study

(2008) Themistocles L. Assimes et al.   HUMAN MOLECULAR GENETICS

Replication of the association between a chromosome 9p21 polymorphism and coronary artery disease in Japanese and Korean populations

(2008) Kunihiko Hinohara et al.   JOURNAL OF HUMAN GENETICS

Four SNPs on Chromosome 9p21 in a South Korean Population Implicate a Genetic Locus That Confers High Cross-Race Risk for Development of Coronary Artery Disease

(2007) Gong-Qing Shen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY