Nonlinear dynamics of early atherosclerotic plaque formation may determine the efficacy of high density lipoproteins (HDL) in plaque regression

HDL mimetic CER-001 targets atherosclerotic plaques in patients

(2016) Kang He Zheng et al.   ATHEROSCLEROSIS

HDL infusion for the management of atherosclerosis

(2016) Kang H. Zheng et al.   CURRENT OPINION IN LIPIDOLOGY

Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA

(2015) Ruud S. Kootte et al.   JOURNAL OF LIPID RESEARCH

Bifurcation and dynamics in a mathematical model of early atherosclerosis

(2015) Alexander D. Chalmers et al.   JOURNAL OF MATHEMATICAL BIOLOGY

High-Density Lipoprotein Function Measurement in Human Studies: Focus on Cholesterol Efflux Capacity

(2015) Anand Rohatgi   PROGRESS IN CARDIOVASCULAR DISEASES

A Mathematical Model of Atherosclerosis with Reverse Cholesterol Transport and Associated Risk Factors

(2014) Avner Friedman et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Athero-protective Effects of High Density Lipoproteins (HDL): An ODE Model of the Early Stages of Atherosclerosis

(2014) Anna Cohen et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Mechanisms That Regulate Macrophage Burden in Atherosclerosis

(2014) Gwendalyn J Randolph   CIRCULATION RESEARCH

High-Density Lipoprotein and Atherosclerosis Regression

(2014) Jonathan E. Feig et al.   CIRCULATION RESEARCH

Effects of the high-density lipoprotein mimetic agent CER-001 on coronary atherosclerosis in patients with acute coronary syndromes: a randomized trial

(2014) J.-C. Tardif et al.   EUROPEAN HEART JOURNAL

Macrophage phenotypes in atherosclerosis

(2014) Sophie Colin et al.   IMMUNOLOGICAL REVIEWS

HDL-targeted therapies: progress, failures and future

(2014) Bronwyn A. Kingwell et al.   NATURE REVIEWS DRUG DISCOVERY

The LDL-HDL Profile Determines the Risk of Atherosclerosis: A Mathematical Model

(2014) Wenrui Hao et al.   PLoS One

Dynamic Aspects of Macrophage Polarization during Atherosclerosis Progression and Regression

(2014) Michael Peled et al.   Frontiers in Immunology

CER-001, a HDL-mimetic, stimulates the reverse lipid transport and atherosclerosis regression in high cholesterol diet-fed LDL-receptor deficient mice

(2013) Claudine Tardy et al.   ATHEROSCLEROSIS

HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment

(2013) et al.   EUROPEAN HEART JOURNAL

Striking Differences Between the Atheroprotective Effects of High Density Lipoproteins in Early-stage and Late-stage Atherosclerosis: Insights into the Lack of Efficacy of HDL-raising Therapy

(2013) J. Morton et al.   Heart Lung and Circulation

Radial artery intima-media ratio predicts presence of coronary thin-cap fibroatheroma: A frequency domain-optical coherence tomography study

(2013) L. Di Vito et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

A multiple ascending dose study of CSL112, an infused formulation of ApoA-I

(2013) Rachael Easton et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Mathematical modelling of atheroma plaque formation and development in coronary arteries

(2013) M. Cilla et al.   Journal of the Royal Society Interface

HDL Induces the Expression of the M2 Macrophage Markers Arginase 1 and Fizz-1 in a STAT6-Dependent Process

(2013) Marie Sanson et al.   PLoS One

Effects of Dalcetrapib in Patients with a Recent Acute Coronary Syndrome

(2012) Gregory G. Schwartz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe–/– mice during disease regression

(2011) Stephane Potteaux et al.   JOURNAL OF CLINICAL INVESTIGATION

Regression and stabilization of advanced murine atherosclerotic lesions: a comparison of LDL lowering and HDL raising gene transfer strategies

(2011) Eline Van Craeyveld et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

HDL promotes rapid atherosclerosis regression in mice and alters inflammatory properties of plaque monocyte-derived cells

(2011) J. E. Feig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An ODE Model of Early Stages of Atherosclerosis: Mechanisms of the Inflammatory Response

(2010) Anna Ougrinovskaia et al.   BULLETIN OF MATHEMATICAL BIOLOGY

A First-in-Man, Randomized, Placebo-Controlled Study to Evaluate the Safety and Feasibility of Autologous Delipidated High-Density Lipoprotein Plasma Infusions in Patients With Acute Coronary Syndrome

(2010) Ron Waksman et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Patient-specific three-dimensional simulation of LDL accumulation in a human left coronary artery in its healthy and atherosclerotic states

(2009) Ufuk Olgac et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The transport of LDL across the deformable arterial wall: the effect of endothelial cell turnover and intimal deformation under hypertension

(2009) Mahsa Dabagh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Age-Associated Decrease of High-Density Lipoprotein-Mediated Reverse Cholesterol Transport Activity

(2009) Hicham Berrougui et al.   REJUVENATION RESEARCH

Infusion of Reconstituted High-Density Lipoprotein Leads to Acute Changes in Human Atherosclerotic Plaque

(2008) James A. Shaw et al.   CIRCULATION RESEARCH