Tau Spreading Mechanisms; Implications for Dysfunctional Tauopathies
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Tau Spreading Mechanisms; Implications for Dysfunctional Tauopathies
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 3, Pages 645
Publisher
MDPI AG
Online
2018-02-27
DOI
10.3390/ijms19030645
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A Highly Selective and Specific PET Tracer for Imaging of Tau Pathologies
- (2018) Wei Zhang et al. JOURNAL OF ALZHEIMERS DISEASE
- Rab7A regulates tau secretion
- (2017) Lilia Rodriguez et al. JOURNAL OF NEUROCHEMISTRY
- The release and trans-synaptic transmission of Tau via exosomes
- (2017) Yipeng Wang et al. Molecular Neurodegeneration
- Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease
- (2017) Carmen Venegas et al. NATURE
- Cryo-EM structures of tau filaments from Alzheimer’s disease
- (2017) Anthony W. P. Fitzpatrick et al. NATURE
- Tau secretion is correlated to an increase of Golgi dynamics
- (2017) Nguyen-Vi Mohamed et al. PLoS One
- Identification of the Tau phosphorylation pattern that drives its aggregation
- (2017) Clément Despres et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Extracellular Tau and Its Potential Role in the Propagation of Tau Pathology
- (2017) Kaoru Yamada Frontiers in Neuroscience
- Interneuronal Transfer of Human Tau Between Lamprey Central Neurons in situ
- (2017) WonHee Kim et al. JOURNAL OF ALZHEIMERS DISEASE
- Interactions of GFAP with ceftriaxone and phenytoin: SRCD and molecular docking and dynamic simulation
- (2016) Paolo Ruzza et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative‐associated proteins
- (2016) Sarah N Fontaine et al. EMBO JOURNAL
- A critical appraisal of the pathogenic protein spread hypothesis of neurodegeneration
- (2016) Dominic M. Walsh et al. NATURE REVIEWS NEUROSCIENCE
- Tau Prion Strains Dictate Patterns of Cell Pathology, Progression Rate, and Regional Vulnerability In Vivo
- (2016) Sarah K. Kaufman et al. NEURON
- Secretion of full-length tau or tau fragments in a cell culture model
- (2016) Mar Pérez et al. NEUROSCIENCE LETTERS
- Tunneling nanotubes: A possible highway in the spreading of tau and other prion-like proteins in neurodegenerative diseases
- (2016) Saida Abounit et al. Prion
- Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies
- (2016) Meryem Tardivel et al. Acta Neuropathologica Communications
- Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory
- (2016) M. Fá et al. Scientific Reports
- Propagation of tau pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies
- (2015) Jada Lewis et al. ACTA NEUROPATHOLOGICA
- Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study
- (2015) Massimo S. Fiandaca et al. Alzheimers & Dementia
- Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation
- (2015) Hilda Mirbaha et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits
- (2015) Sang-Won Min et al. NATURE MEDICINE
- Depletion of microglia and inhibition of exosome synthesis halt tau propagation
- (2015) Hirohide Asai et al. NATURE NEUROSCIENCE
- Spreading of pathology in neurodegenerative diseases: a focus on human studies
- (2015) Johannes Brettschneider et al. NATURE REVIEWS NEUROSCIENCE
- Tau in physiology and pathology
- (2015) Yipeng Wang et al. NATURE REVIEWS NEUROSCIENCE
- Human secreted tau increases amyloid-beta production
- (2015) Jessica Bright et al. NEUROBIOLOGY OF AGING
- Invited review: Prion-like transmission and spreading of tau pathology
- (2015) Florence Clavaguera et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer’s disease mouse model
- (2015) Gerhard Leinenga et al. Science Translational Medicine
- Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody
- (2015) Wenjie Luo et al. Scientific Reports
- Acellular approaches for regenerative medicine: on the verge of clinical trials with extracellular membrane vesicles?
- (2015) Almudena Fuster-Matanzo et al. Stem Cell Research & Therapy
- Amplification of Tau Fibrils from Minute Quantities of Seeds
- (2014) Virginia Meyer et al. BIOCHEMISTRY
- Selective vulnerability to neurodegenerative disease: the curious case of Prion Protein
- (2014) W. S. Jackson Disease Models & Mechanisms
- Extracellular Monomeric Tau Protein Is Sufficient to Initiate the Spread of Tau Protein Pathology
- (2014) Claire H. Michel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conformation Determines the Seeding Potencies of Native and Recombinant Tau Aggregates
- (2014) Benjamin Falcon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neuronal activity regulates extracellular tau in vivo
- (2014) Kaoru Yamada et al. JOURNAL OF EXPERIMENTAL MEDICINE
- O-GlcNAc Modification of tau Directly Inhibits Its Aggregation without Perturbing the Conformational Properties of tau Monomers
- (2014) Scott A. Yuzwa et al. JOURNAL OF MOLECULAR BIOLOGY
- Activity-Dependent Tau Protein Translocation to Excitatory Synapse Is Disrupted by Exposure to Amyloid-Beta Oligomers
- (2014) M. L. Frandemiche et al. JOURNAL OF NEUROSCIENCE
- Tideglusib reduces progression of brain atrophy in progressive supranuclear palsy in a randomized trial
- (2014) Günter U. Höglinger et al. MOVEMENT DISORDERS
- Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases
- (2014) Jing L Guo et al. NATURE MEDICINE
- Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies
- (2014) David W. Sanders et al. NEURON
- Ectosomes: A New Mechanism for Non-Exosomal Secretion of Tau Protein
- (2014) Simon Dujardin et al. PLoS One
- SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination
- (2014) Hong-Bin Luo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The role of extracellular Tau in the spreading of neurofibrillary pathology
- (2014) Miguel Medina et al. Frontiers in Cellular Neuroscience
- A major role for Tau in neuronal DNA and RNA protection in vivo under physiological and hyperthermic conditions
- (2014) Marie Violet et al. Frontiers in Cellular Neuroscience
- Starvation and inhibition of lysosomal function increased tau secretion by primary cortical neurons
- (2014) Nguyen-Vi Mohamed et al. Scientific Reports
- Open questions for Alzheimer’s disease immunotherapy
- (2014) Todd E Golde Alzheimers Research & Therapy
- Characterization of tau oligomeric seeds in progressive supranuclear palsy
- (2014) Julia E Gerson et al. Acta Neuropathologica Communications
- Ceftriaxone Blocks the Polymerization of α-Synuclein and Exerts Neuroprotective Effects in Vitro
- (2013) Paolo Ruzza et al. ACS Chemical Neuroscience
- Physiological release of endogenous tau is stimulated by neuronal activity
- (2013) Amy M Pooler et al. EMBO REPORTS
- Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance
- (2013) Casey Cook et al. HUMAN MOLECULAR GENETICS
- Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy
- (2013) M. Iba et al. JOURNAL OF NEUROSCIENCE
- Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
- (2013) Mathias Jucker et al. NATURE
- Tau Immunotherapy and Imaging
- (2013) Einar M. Sigurdsson Neurodegenerative Diseases
- Anti-Tau Antibodies that Block Tau Aggregate Seeding In Vitro Markedly Decrease Pathology and Improve Cognition In Vivo
- (2013) Kiran Yanamandra et al. NEURON
- Tau Passive Immunotherapy in Mutant P301L Mice: Antibody Affinity versus Specificity
- (2013) Cristina d’Abramo et al. PLoS One
- Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity
- (2013) H. C. Christianson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Brain homogenates from human tauopathies induce tau inclusions in mouse brain
- (2013) Florence Clavaguera et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
- (2013) B. B. Holmes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The spectrum of disease in chronic traumatic encephalopathy
- (2012) Ann C. McKee et al. BRAIN
- MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies
- (2012) Daniah Trabzuni et al. HUMAN MOLECULAR GENETICS
- Extracellular Tau Levels Are Influenced by Variability in Tau That Is Associated with Tauopathies
- (2012) Celeste M. Karch et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons
- (2012) Jessica W. Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Trans-cellular Propagation of Tau Aggregation by Fibrillar Species
- (2012) Najla Kfoury et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Transthyretin Amyloidoses: From Delineating the Molecular Mechanism of Aggregation Linked to Pathology to a Regulatory-Agency-Approved Drug
- (2012) Steven M. Johnson et al. JOURNAL OF MOLECULAR BIOLOGY
- Hyperdynamic Microtubules, Cognitive Deficits, and Pathology Are Improved in Tau Transgenic Mice with Low Doses of the Microtubule-Stabilizing Agent BMS-241027
- (2012) D. M. Barten et al. JOURNAL OF NEUROSCIENCE
- Antibody-Aided Clearance of Extracellular -Synuclein Prevents Cell-to-Cell Aggregate Transmission
- (2012) E.-J. Bae et al. JOURNAL OF NEUROSCIENCE
- Constitutive secretion of tau protein by an unconventional mechanism
- (2012) Xiyun Chai et al. NEUROBIOLOGY OF DISEASE
- Trans-Synaptic Spread of Tau Pathology In Vivo
- (2012) Li Liu et al. PLoS One
- Hyperphosphorylation and Cleavage at D421 Enhance Tau Secretion
- (2012) Vanessa Plouffe et al. PLoS One
- Variations in Filament Conformation Dictate Seeding Barrier between Three- and Four-Repeat Tau
- (2011) Paul D. Dinkel et al. BIOCHEMISTRY
- Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles
- (2011) Diana Simón et al. FEBS LETTERS
- Seeding of Normal Tau by Pathological Tau Conformers Drives Pathogenesis of Alzheimer-like Tangles
- (2011) Jing L. Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease
- (2011) Sudad Saman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- In Vivo Microdialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice
- (2011) K. Yamada et al. JOURNAL OF NEUROSCIENCE
- Post-translational modifications of tau protein: Implications for Alzheimer's disease
- (2011) Ludovic Martin et al. NEUROCHEMISTRY INTERNATIONAL
- Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
- (2010) Lars M. Ittner et al. CELL
- Secretion of human tau fragments resembling CSF-tau in Alzheimer's disease is modulated by the presence of the exon 2 insert
- (2010) WonHee Kim et al. FEBS LETTERS
- Tissue-nonspecific Alkaline Phosphatase Promotes the Neurotoxicity Effect of Extracellular Tau
- (2010) Miguel Díaz-Hernández et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Seeded Aggregation and Toxicity of α-Synuclein and Tau
- (2010) Takashi Nonaka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nuclear Tau, a Key Player in Neuronal DNA Protection
- (2010) Audrey Sultan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Adenovirus Type 3 Dodecahedron's RGD Loop Comprises an HSPG Binding Site That Influences Integrin Binding
- (2010) E. Gout et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- A Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines
- (2010) H. Zempel et al. JOURNAL OF NEUROSCIENCE
- Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
- (2010) Sang-Won Min et al. NEURON
- Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
- (2010) Brian R. Hoover et al. NEURON
- GSK3: A possible link between beta amyloid peptide and tau protein
- (2009) Félix Hernández et al. EXPERIMENTAL NEUROLOGY
- Phosphorylated Tau Interacts with c-Jun N-terminal Kinase-interacting Protein 1 (JIP1) in Alzheimer Disease
- (2009) Lars M. Ittner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Propagation of Tau Misfolding from the Outside to the Inside of a Cell
- (2009) Bess Frost et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transmission and spreading of tauopathy in transgenic mouse brain
- (2009) Florence Clavaguera et al. NATURE CELL BIOLOGY
- Virus entry by macropinocytosis
- (2009) Jason Mercer et al. NATURE CELL BIOLOGY
- The Transcellular Spread of Cytosolic Amyloids, Prions, and Prionoids
- (2009) Adriano Aguzzi et al. NEURON
- Axonal Transport Rates In Vivo Are Unaffected by Tau Deletion or Overexpression in Mice
- (2008) A. Yuan et al. JOURNAL OF NEUROSCIENCE
- Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells
- (2008) A. Gómez-Ramos et al. MOLECULAR AND CELLULAR NEUROSCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search