Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases
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Title
Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases
Authors
Keywords
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Journal
NATURE MEDICINE
Volume 20, Issue 2, Pages 130-138
Publisher
Springer Nature
Online
2014-02-07
DOI
10.1038/nm.3457
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Note: Only part of the references are listed.- Stages of pTDP-43 pathology in amyotrophic lateral sclerosis
- (2013) Johannes Brettschneider et al. ANNALS OF NEUROLOGY
- Conformational Features of Tau Fibrils from Alzheimer’s Disease Brain Are Faithfully Propagated by Unmodified Recombinant Protein
- (2013) Olga A. Morozova et al. BIOCHEMISTRY
- Prion-like spreading of pathological α-synuclein in brain
- (2013) Masami Masuda-Suzukake et al. BRAIN
- Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue
- (2013) Jun-Xia Lu et al. CELL
- Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons
- (2013) Jing L. Guo et al. CELL
- Caudo-rostral brain spreading of α-synuclein through vagal connections
- (2013) Ayse Ulusoy et al. EMBO Molecular Medicine
- Physiological release of endogenous tau is stimulated by neuronal activity
- (2013) Amy M Pooler et al. EMBO REPORTS
- Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice
- (2013) Götz Heilbronner et al. EMBO REPORTS
- Neurofibrillary tangle-like tau pathology induced by synthetic tau fibrils in primary neurons over-expressing mutant tau
- (2013) Jing L. Guo et al. FEBS LETTERS
- Lewy Body-like α-Synuclein Aggregates Resist Degradation and Impair Macroautophagy
- (2013) Selcuk A. Tanik et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy
- (2013) M. Iba et al. JOURNAL OF NEUROSCIENCE
- Brain homogenates from human tauopathies induce tau inclusions in mouse brain
- (2013) Florence Clavaguera et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism
- (2013) S. I. A. Cohen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier
- (2013) J. A. Couch et al. Science Translational Medicine
- Prion-like Properties of Pathological TDP-43 Aggregates from Diseased Brains
- (2013) Takashi Nonaka et al. Cell Reports
- Evaluation of Potential Infectivity of Alzheimer and Parkinson Disease Proteins in Recipients of Cadaver-Derived Human Growth Hormone
- (2013) David J. Irwin et al. JAMA Neurology
- Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport
- (2012) Eric C. Freundt et al. ANNALS OF NEUROLOGY
- Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons
- (2012) Jessica W. Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Trans-cellular Propagation of Tau Aggregation by Fibrillar Species
- (2012) Najla Kfoury et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
- (2012) Kelvin C. Luk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Exosomal cell-to-cell transmission of alpha synuclein oligomers
- (2012) Karin M Danzer et al. Molecular Neurodegeneration
- Propagation of Tau Pathology in a Model of Early Alzheimer's Disease
- (2012) Alix de Calignon et al. NEURON
- Total CSF α-synuclein is lower in de novo Parkinson patients than in healthy subjects
- (2012) Brit Mollenhauer et al. NEUROSCIENCE LETTERS
- Trans-Synaptic Spread of Tau Pathology In Vivo
- (2012) Li Liu et al. PLoS One
- Purified and synthetic Alzheimer's amyloid beta (A ) prions
- (2012) J. Stohr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau
- (2012) Cristian A. Lasagna-Reeves et al. Scientific Reports
- Alzheimer’s pathogenesis: is there neuron-to-neuron propagation?
- (2011) Heiko Braak et al. ACTA NEUROPATHOLOGICA
- Pathogenic protein seeding in alzheimer disease and other neurodegenerative disorders
- (2011) Mathias Jucker et al. ANNALS OF NEUROLOGY
- Seeding of Normal Tau by Pathological Tau Conformers Drives Pathogenesis of Alzheimer-like Tangles
- (2011) Jing L. Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease
- (2011) Sudad Saman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization of Prefibrillar Tau Oligomersin Vitroand in Alzheimer Disease
- (2011) Kristina R. Patterson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
- (2011) Christian Hansen et al. JOURNAL OF CLINICAL INVESTIGATION
- Conformational Transformation and Selection of Synthetic Prion Strains
- (2011) Sina Ghaemmaghami et al. JOURNAL OF MOLECULAR BIOLOGY
- In Vivo Microdialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice
- (2011) K. Yamada et al. JOURNAL OF NEUROSCIENCE
- Prion propagation and toxicity in vivo occur in two distinct mechanistic phases
- (2011) Malin K. Sandberg et al. NATURE
- Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
- (2011) Laura A. Volpicelli-Daley et al. NEURON
- Assessment of α-Synuclein Secretion in Mouse and Human Brain Parenchyma
- (2011) Evangelia Emmanouilidou et al. PLoS One
- Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells
- (2011) Christian Münch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vivo demonstration that -synuclein oligomers are toxic
- (2011) B. Winner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Recombinant prion protein induces a new transmissible prion disease in wild-type animals
- (2010) Natallia Makarava et al. ACTA NEUROPATHOLOGICA
- Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
- (2010) Lars M. Ittner et al. CELL
- Mechanisms Underlying Inflammation in Neurodegeneration
- (2010) Christopher K. Glass et al. CELL
- Mutation-dependent Polymorphism of Cu,Zn-Superoxide Dismutase Aggregates in the Familial Form of Amyotrophic Lateral Sclerosis
- (2010) Yoshiaki Furukawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Seeded Aggregation and Toxicity of α-Synuclein and Tau
- (2010) Takashi Nonaka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cell-Produced -Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival
- (2010) E. Emmanouilidou et al. JOURNAL OF NEUROSCIENCE
- Induction of Amyloid Fibrils by the C-Terminal Fragments of TDP-43 in Amyotrophic Lateral Sclerosis
- (2010) Allan K.-H. Chen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Prion-like transmission of protein aggregates in neurodegenerative diseases
- (2010) Patrik Brundin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cell-to-cell transmission of non-prion protein aggregates
- (2010) Seung-Jae Lee et al. Nature Reviews Neurology
- Darwinian Evolution of Prions in Cell Culture
- (2010) J. Li et al. SCIENCE
- Generating a Prion with Bacterially Expressed Recombinant Prion Protein
- (2010) F. Wang et al. SCIENCE
- Peripherally Applied A -Containing Inoculates Induce Cerebral -Amyloidosis
- (2010) Y. S. Eisele et al. SCIENCE
- Cerebrospinal Fluid β-Amyloid 42 and Tau Proteins as Biomarkers of Alzheimer-Type Pathologic Changes in the Brain
- (2009) Tero Tapiola et al. ARCHIVES OF NEUROLOGY
- Pre-fibrillar α-synuclein variants with impaired β-structure increase neurotoxicity in Parkinson's disease models
- (2009) Damla Pinar Karpinar et al. EMBO JOURNAL
- Conversion of Wild-type α-Synuclein into Mutant-type Fibrils and Its Propagation in the Presence of A30P Mutant
- (2009) Motokuni Yonetani et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Propagation of Tau Misfolding from the Outside to the Inside of a Cell
- (2009) Bess Frost et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transmission and spreading of tauopathy in transgenic mouse brain
- (2009) Florence Clavaguera et al. NATURE CELL BIOLOGY
- Prions hijack tunnelling nanotubes for intercellular spread
- (2009) Karine Gousset et al. NATURE CELL BIOLOGY
- Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates
- (2009) Pei-Hsien Ren et al. NATURE CELL BIOLOGY
- Prions: Protein Aggregation and Infectious Diseases
- (2009) Adriano Aguzzi et al. PHYSIOLOGICAL REVIEWS
- Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein
- (2009) P. Desplats et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distinct conformations of in vitro and in vivo amyloids of huntingtin-exon1 show different cytotoxicity
- (2009) Y. Nekooki-Machida et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Design and construction of diverse mammalian prion strains
- (2009) D. W. Colby et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exogenous -synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
- (2009) K. C. Luk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases
- (2008) Wen-Lang Lin et al. ACTA NEUROPATHOLOGICA
- Molecular Mechanisms of Prion Pathogenesis
- (2008) Adriano Aguzzi et al. Annual Review of Pathology-Mechanisms of Disease
- Fine structural analysis of the neuronal inclusions of frontotemporal lobar degeneration with TDP-43 proteinopathy
- (2008) Julian R. Thorpe et al. JOURNAL OF NEURAL TRANSMISSION
- Expanded Repertoire of AAV Vector Serotypes Mediate Unique Patterns of Transduction in Mouse Brain
- (2008) Cassia N Cearley et al. MOLECULAR THERAPY
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
- (2008) Jia-Yi Li et al. NATURE MEDICINE
- Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
- (2008) Jeffrey H Kordower et al. NATURE MEDICINE
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