Ectosomes: A New Mechanism for Non-Exosomal Secretion of Tau Protein

Interneuronal Transfer of Human Tau Between Lamprey Central Neurons in situ

(2017) WonHee Kim et al.   JOURNAL OF ALZHEIMERS DISEASE

Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles

(2014) D. L. Castillo-Carranza et al.   JOURNAL OF NEUROSCIENCE

Physiological release of endogenous tau is stimulated by neuronal activity

(2013) Amy M Pooler et al.   EMBO REPORTS

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Cerebrospinal Fluid Tau Cleaved by Caspase-6 Reflects Brain Levels and Cognition in Aging and Alzheimer Disease

(2013) Jasmine Ramcharitar et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Circulating Extracellular Vesicles in Cancer Diagnosis and Monitoring

(2013) Dong-Sic Choi et al.   Molecular Diagnosis & Therapy

Lentiviral Delivery of the Human Wild-type Tau Protein Mediates a Slow and Progressive Neurodegenerative Tau Pathology in the Rat Brain

(2013) Raphaëlle Caillierez et al.   MOLECULAR THERAPY

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Prion-Like Propagation of Protein Aggregation and Related Therapeutic Strategies

(2013) Sarah K. Kaufman et al.   Neurotherapeutics

Profiling Murine Tau with 0N, 1N and 2N Isoform-Specific Antibodies in Brain and Peripheral Organs Reveals Distinct Subcellular Localization, with the 1N Isoform Being Enriched in the Nucleus

(2013) Chang Liu et al.   PLoS One

Formation and Propagation of Tau Oligomeric Seeds

(2013) Julia E. Gerson et al.   Frontiers in Neurology

Targeting Phospho-Ser422 by Active Tau Immunotherapy in the THYTau22 Mouse Model: A Suitable Therapeutic Approach

(2012) Nadege Zommer et al.   Current Alzheimer Research

Sstr2A: a relevant target for the delivery of genes into human glioblastoma cells using fiber-modified adenoviral vectors

(2012) K Lécolle et al.   GENE THERAPY

Extracellular Tau Levels Are Influenced by Variability in Tau That Is Associated with Tauopathies

(2012) Celeste M. Karch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trans-cellular Propagation of Tau Aggregation by Fibrillar Species

(2012) Najla Kfoury et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paired Helical Filaments from Alzheimer Disease Brain Induce Intracellular Accumulation of Tau Protein in Aggresomes

(2012) Ismael Santa-Maria et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Constitutive secretion of tau protein by an unconventional mechanism

(2012) Xiyun Chai et al.   NEUROBIOLOGY OF DISEASE

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

(2012) Alix de Calignon et al.   NEURON

Trans-Synaptic Spread of Tau Pathology In Vivo

(2012) Li Liu et al.   PLoS One

Hyperphosphorylation and Cleavage at D421 Enhance Tau Secretion

(2012) Vanessa Plouffe et al.   PLoS One

Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation

(2012) Hina Kalra et al.   PLOS BIOLOGY

Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau

(2011) Alessia Usardi et al.   FEBS Journal

Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles

(2011) Diana Simón et al.   FEBS LETTERS

Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease

(2011) Sudad Saman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-derived microparticles in atherosclerosis: biomarkers and targets for pharmacological modulation?

(2011) Morgane Baron et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

In Vivo Microdialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice

(2011) K. Yamada et al.   JOURNAL OF NEUROSCIENCE

Dynamic association of tau with neuronal membranes is regulated by phosphorylation

(2011) Amy M. Pooler et al.   NEUROBIOLOGY OF AGING

The pathological process underlying Alzheimer’s disease in individuals under thirty

(2010) Heiko Braak et al.   ACTA NEUROPATHOLOGICA

Synergy and antagonism of macroautophagy and chaperone-mediated autophagy in a cell model of pathological tau aggregation

(2010) Yipeng Wang et al.   Autophagy

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Secretion of human tau fragments resembling CSF-tau in Alzheimer's disease is modulated by the presence of the exon 2 insert

(2010) WonHee Kim et al.   FEBS LETTERS

Tissue-nonspecific Alkaline Phosphatase Promotes the Neurotoxicity Effect of Extracellular Tau

(2010) Miguel Díaz-Hernández et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Tau, a Key Player in Neuronal DNA Protection

(2010) Audrey Sultan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of Human Tau in Cerebrospinal Fluid

(2010) Katja Hanisch et al.   JOURNAL OF PROTEOME RESEARCH

Exosomes: Extracellular organelles important in intercellular communication

(2010) Suresh Mathivanan et al.   Journal of Proteomics

Protein degradation, aggregation, and misfolding

(2010) Ana Maria Cuervo et al.   MOVEMENT DISORDERS

Caspase activation precedes and leads to tangles

(2010) Alix de Calignon et al.   NATURE

Tissue Factor, Lipid Rafts, and Microparticles

(2010) Pavel Davizon et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Propagation of Tau Misfolding from the Outside to the Inside of a Cell

(2009) Bess Frost et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-derived microparticles: a new challenge in neuroscience

(2009) Loïc Doeuvre et al.   JOURNAL OF NEUROCHEMISTRY

Transmission and spreading of tauopathy in transgenic mouse brain

(2009) Florence Clavaguera et al.   NATURE CELL BIOLOGY

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Tau as a biomarker of neurodegenerative diseases

(2008) Susanna Schraen-Maschke et al.   Biomarkers in Medicine

Pattern of Tau forms in CSF is altered in progressive supranuclear palsy

(2007) B. Borroni et al.   NEUROBIOLOGY OF AGING