Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD)
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD)
Authors
Keywords
-
Journal
FASEB JOURNAL
Volume 32, Issue 5, Pages 2735-2746
Publisher
FASEB
Online
2018-01-26
DOI
10.1096/fj.201700909r
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Genome-wide screen identifies novel machineries required for both ciliogenesis and cell cycle arrest upon serum starvation
- (2016) Ji Hyun Kim et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The importance of total kidney volume in evaluating progression of polycystic kidney disease
- (2016) Jared J. Grantham et al. Nature Reviews Nephrology
- 2-Deoxy-D-Glucose Ameliorates PKD Progression
- (2015) M. Chiaravalli et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes
- (2015) Gabrielle Wheway et al. NATURE CELL BIOLOGY
- The hallmarks of cancer: relevance to the pathogenesis of polycystic kidney disease
- (2015) Tamina Seeger-Nukpezah et al. Nature Reviews Nephrology
- Vascular complications in autosomal dominant polycystic kidney disease
- (2015) Ronald D. Perrone et al. Nature Reviews Nephrology
- Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle
- (2015) Sehyun Kim et al. Nature Communications
- Opposing Effects of Inhibitors of Aurora-A and EGFR in Autosomal-Dominant Polycystic Kidney Disease
- (2015) Anna S. Nikonova et al. Frontiers in Oncology
- HSP90 Inhibition Suppresses Lipopolysaccharide-Induced Lung Inflammation In Vivo
- (2015) Andrew Lilja et al. PLoS One
- Pharmacological management of polycystic kidney disease
- (2014) Rudolf P Wüthrich et al. EXPERT OPINION ON PHARMACOTHERAPY
- The Tumor Suppressor pVHL Down-regulates Never-in-Mitosis A-related Kinase 8 via Hypoxia-inducible Factors to Maintain Cilia in Human Renal Cancer Cells
- (2014) Xiao-Fei Ding et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Blood Pressure in Early Autosomal Dominant Polycystic Kidney Disease
- (2014) Robert W. Schrier et al. NEW ENGLAND JOURNAL OF MEDICINE
- Angiotensin Blockade in Late Autosomal Dominant Polycystic Kidney Disease
- (2014) Vicente E. Torres et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inhibiting Heat Shock Protein 90 (HSP90) Limits the Formation of Liver Cysts Induced by Conditional Deletion of Pkd1 in Mice
- (2014) Zachary B. Smithline et al. PLoS One
- Nedd9 restrains renal cystogenesis in Pkd1-/- mice
- (2014) A. S. Nikonova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ubiquitin-proteasome system controls ciliogenesis at the initial step of axoneme extension
- (2014) Kousuke Kasahara et al. Nature Communications
- Polycystin Signaling Is Required for Directed Endothelial Cell Migration and Lymphatic Development
- (2014) Patricia Outeda et al. Cell Reports
- Cost-Effectiveness of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease
- (2013) Kevin F. Erickson et al. ANNALS OF INTERNAL MEDICINE
- VDAC3 and Mps1 negatively regulate ciliogenesis
- (2013) Shubhra Majumder et al. CELL CYCLE
- A Multicenter Phase II Study of Ganetespib Monotherapy in Patients with Genotypically Defined Advanced Non-Small Cell Lung Cancer
- (2013) M. A. Socinski et al. CLINICAL CANCER RESEARCH
- Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease
- (2013) Ming Ma et al. NATURE GENETICS
- Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy
- (2013) Isaline Rowe et al. NATURE MEDICINE
- Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease
- (2013) T. Seeger-Nukpezah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
- (2012) Mikko Taipale et al. CELL
- The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies
- (2012) Junmin Pan et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Aurora A kinase (AURKA) in normal and pathological cell division
- (2012) Anna S. Nikonova et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The extracellular matrix and ciliary signaling
- (2012) Tamina Seeger-Nukpezah et al. CURRENT OPINION IN CELL BIOLOGY
- Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells
- (2012) Akihito Inoko et al. JOURNAL OF CELL BIOLOGY
- Plk2 regulates centriole duplication through phosphorylation-mediated degradation of Fbxw7 (human Cdc4)
- (2012) Onur Cizmecioglu et al. JOURNAL OF CELL SCIENCE
- Systematic Identification of the HSP90 Regulated Proteome
- (2012) Zhixiang Wu et al. MOLECULAR & CELLULAR PROTEOMICS
- Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis
- (2012) Olga V. Plotnikova et al. MOLECULAR BIOLOGY OF THE CELL
- Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease
- (2012) Vicente E. Torres et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Nek8 protein kinase, mutated in the human cystic kidney disease nephronophthisis, is both activated and degraded during ciliogenesis
- (2011) Detina Zalli et al. HUMAN MOLECULAR GENETICS
- Aurora A kinase activity influences calcium signaling in kidney cells
- (2011) Olga V. Plotnikova et al. JOURNAL OF CELL BIOLOGY
- Mechanism-Based Therapeutics for Autosomal Dominant Polycystic Kidney Disease: Recent Progress and Future Prospects
- (2011) Ming-Yang Chang et al. NEPHRON CLINICAL PRACTICE
- An Interaction Network Predicted from Public Data as a Discovery Tool: Application to the Hsp90 Molecular Chaperone Machine
- (2011) Pablo C. Echeverría et al. PLoS One
- Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis
- (2011) V. Takiar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A systems-biology approach to understanding the ciliopathy disorders
- (2011) Ji Eun Lee et al. Genome Medicine
- The HALT Polycystic Kidney Disease Trials: Design and Implementation
- (2010) A. B. Chapman et al. Clinical Journal of the American Society of Nephrology
- Sirolimus and Kidney Growth in Autosomal Dominant Polycystic Kidney Disease
- (2010) Andreas L. Serra et al. NEW ENGLAND JOURNAL OF MEDICINE
- Rapid calcium-dependent activation of Aurora-A kinase
- (2010) Olga V. Plotnikova et al. Nature Communications
- ERK1/2-Dependent Vascular Endothelial Growth Factor Signaling Sustains Cyst Growth in Polycystin-2 Defective Mice
- (2009) Carlo Spirli et al. GASTROENTEROLOGY
- Mammalian target of rapamycin regulates vascular endothelial growth factor-dependent liver cyst growth in polycystin-2-defective mice
- (2009) Carlo Spirli et al. HEPATOLOGY
- Autosomal dominant polycystic kidney disease: the last 3 years
- (2009) Vicente E. Torres et al. KIDNEY INTERNATIONAL
- Polycystic Kidney Disease
- (2008) Peter C. Harris et al. Annual Review of Medicine
- Src Inhibition Ameliorates Polycystic Kidney Disease
- (2008) W. E. Sweeney et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Monitoring kidney and renal cyst volumes applying MR approaches on a rapamycin treated mouse model of ADPKD
- (2008) Wilfried Reichardt et al. MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
- STRING 8--a global view on proteins and their functional interactions in 630 organisms
- (2008) L. J. Jensen et al. NUCLEIC ACIDS RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started