Mechanism-Based Therapeutics for Autosomal Dominant Polycystic Kidney Disease: Recent Progress and Future Prospects

Effect of statin therapy on disease progression in pediatric ADPKD: Design and baseline characteristics of participants

(2011) Melissa A. Cadnapaphornchai et al.   Contemporary Clinical Trials

mTOR Inhibitors and Autosomal Dominant Polycystic Kidney Disease

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis

(2011) V. Takiar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of Urinary Biomarkers With Disease Severity in Patients With Autosomal Dominant Polycystic Kidney Disease: A Cross-sectional Analysis

(2010) Esther Meijer et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Therapeutic mTOR Inhibition in Autosomal Dominant Polycystic Kidney Disease: What Is the Appropriate Serum Level?

(2010) G. Canaud et al.   AMERICAN JOURNAL OF TRANSPLANTATION

A phase 2 study of eliglustat tartrate (Genz-112638), an oral substrate reduction therapy for Gaucher disease type 1

(2010) E. Lukina et al.   BLOOD

The therapy of kidney cancer with biomolecular drugs

(2010) G. Di Lorenzo et al.   CANCER TREATMENT REVIEWS

A Pilot Clinical Study to Evaluate Changes in Urine Osmolality and Urine cAMP in Response to Acute and Chronic Water Loading in Autosomal Dominant Polycystic Kidney Disease

(2010) I. Barash et al.   Clinical Journal of the American Society of Nephrology

The HALT Polycystic Kidney Disease Trials: Design and Implementation

(2010) A. B. Chapman et al.   Clinical Journal of the American Society of Nephrology

Rosiglitazone attenuates development of polycystic kidney disease and prolongs survival in Han:SPRD rats

(2010) Bing Dai et al.   CLINICAL SCIENCE

Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts

(2010) S. Xia et al.   DEVELOPMENT

A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes

(2010) Aurélie Giamarchi et al.   EMBO JOURNAL

Rapamycin Ameliorates PKD Resulting from Conditional Inactivation of Pkd1

(2010) J. M. Shillingford et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Randomized Intervention Studies in Human Polycystic Kidney and Liver Disease

(2010) R. W. Schrier   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Randomized Clinical Trial of Long-Acting Somatostatin for Autosomal Dominant Polycystic Kidney and Liver Disease

(2010) M. C. Hogan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sirolimus Therapy to Halt the Progression of ADPKD

(2010) N. Perico et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Primary cilia regulate mTORC1 activity and cell size through Lkb1

(2010) Christopher Boehlke et al.   NATURE CELL BIOLOGY

Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models

(2010) Thomas A Natoli et al.   NATURE MEDICINE

Lipids and renal cystic disease

(2010) R. W. Schrier et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Triptolide reduces cyst formation in a neonatal to adult transition Pkd1 model of ADPKD

(2010) S. J. Leuenroth et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

mTOR Inhibitors in Polycystic Kidney Disease

(2010) Terry Watnick et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sirolimus and Kidney Growth in Autosomal Dominant Polycystic Kidney Disease

(2010) Andreas L. Serra et al.   NEW ENGLAND JOURNAL OF MEDICINE

Everolimus in Patients with Autosomal Dominant Polycystic Kidney Disease

(2010) Gerd Walz et al.   NEW ENGLAND JOURNAL OF MEDICINE

The K+channels KCa3.1 and Kv1.3 as novel targets for asthma therapy

(2009) Peter Bradding et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Case for Water in the Treatment of Polycystic Kidney Disease

(2009) V. E. Torres et al.   Clinical Journal of the American Society of Nephrology

Lanreotide Reduces the Volume of Polycystic Liver: A Randomized, Double-Blind, Placebo-Controlled Trial

(2009) Loes van Keimpema et al.   GASTROENTEROLOGY

Homophilic and heterophilic polycystin 1 interactions regulate E-cadherin recruitment and junction assembly in MDCK cells

(2009) A. J. Streets et al.   JOURNAL OF CELL SCIENCE

Calcimimetic Inhibits Late-Stage Cyst Growth in ADPKD

(2009) V. H. Gattone et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Autosomal dominant polycystic kidney disease: the last 3 years

(2009) Vicente E. Torres et al.   KIDNEY INTERNATIONAL

Peroxisome Proliferator-Activated Receptor Gamma Agonists in Kidney Disease – Future Promise, Present Fears

(2009) Zhiguo Mao et al.   NEPHRON CLINICAL PRACTICE

Comparison of Intracerebral Hemorrhage and Subarachnoid Hemorrhage in Patients with Autosomal-Dominant Polycystic Kidney Disease

(2009) Ming-Yang Chang et al.   NEPHRON CLINICAL PRACTICE

Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models

(2009) Y. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia

(2008) K. I. Ataga et al.   BLOOD

Role of Vasopressin Antagonists

(2008) V. E. Torres   Clinical Journal of the American Society of Nephrology

Sirolimus Reduces Polycystic Liver Volume in ADPKD Patients

(2008) Q. Qian et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Small-Molecule CFTR Inhibitors Slow Cyst Growth in Polycystic Kidney Disease

(2008) B. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Src Inhibition Ameliorates Polycystic Kidney Disease

(2008) W. E. Sweeney et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Triptolide Reduces Cystogenesis in a Model of ADPKD

(2008) S. J. Leuenroth et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

KCa3.1 potassium channels are critical for cAMP-dependent chloride secretion and cyst growth in autosomal-dominant polycystic kidney disease

(2008) Mamdouh Albaqumi et al.   KIDNEY INTERNATIONAL

Effect of calcium-sensing receptor activation in models of autosomal recessive or dominant polycystic kidney disease

(2008) X. Wang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption

(2008) Michelle Boone et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Vasopressin Directly Regulates Cyst Growth in Polycystic Kidney Disease

(2007) X. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Autosomal Dominant Polycystic Kidney Disease: Recent Advances in Pathogenesis and Treatment

(2007) Ming-Yang Chang et al.   NEPHRON PHYSIOLOGY