The hallmarks of cancer: relevance to the pathogenesis of polycystic kidney disease

Hypertension induced by chemotherapeutic and immunosuppresive agents: A new challenge

(2015) Simon Abi Aad et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Understanding Pathologic Variants of Renal Cell Carcinoma: Distilling Therapeutic Opportunities from Biologic Complexity

(2015) Brian Shuch et al.   EUROPEAN UROLOGY

Impaired glomerulogenesis and endothelial cell migration in Pkd1-deficient renal organ cultures

(2014) Isaline Rowe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cytokinesis Failure Triggers Hippo Tumor Suppressor Pathway Activation

(2014) Neil J. Ganem et al.   CELL

Periostin: A Novel Prognostic and Therapeutic Target For Genitourinary Cancer?

(2014) Pier Vitale Nuzzo et al.   Clinical Genitourinary Cancer

The emerging role of the inflammasome in kidney diseases

(2014) Anthony Chang et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Hypertension and Obesity and the Risk of Kidney Cancer in 2 Large Cohorts of US Men and Women

(2014) Kristen M. Sanfilippo et al.   HYPERTENSION

Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer

(2014) Antonios N. Gargalionis et al.   INTERNATIONAL JOURNAL OF CANCER

Multifocal epithelial tumors and field cancerization: stroma as a primary determinant

(2014) G. Paolo Dotto   JOURNAL OF CLINICAL INVESTIGATION

Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease

(2014) Peter C. Harris et al.   JOURNAL OF CLINICAL INVESTIGATION

Polycystic Kidney Disease and Cancer after Renal Transplantation

(2014) J. B. Wetmore et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal-Retinal Ciliopathy Gene Sdccag8 Regulates DNA Damage Response Signaling

(2014) R. Airik et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

New Modalities for Evaluation and Surveillance of Complex Renal Cysts

(2014) Chandy Ellimoottil et al.   JOURNAL OF UROLOGY

Spectrum of diverse genomic alterations define non–clear cell renal carcinoma subtypes

(2014) Steffen Durinck et al.   NATURE GENETICS

The Many Faces of Sirtuins: Coupling of NAD metabolism, sirtuins and lifespan

(2014) Eric Verdin   NATURE MEDICINE

Metformin—mode of action and clinical implications for diabetes and cancer

(2014) Ida Pernicova et al.   Nature Reviews Endocrinology

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer

(2014) Woonyoung Choi et al.   Nature Reviews Urology

Metabolic abnormalities in autosomal dominant polycystic kidney disease

(2014) Z. Mao et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Defective metabolism in polycystic kidney disease: potential for therapy and open questions

(2014) I. Rowe et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

A Quest — Halting the Progression of Autosomal Dominant Polycystic Kidney Disease

(2014) David H. Ellison et al.   NEW ENGLAND JOURNAL OF MEDICINE

Blood Pressure in Early Autosomal Dominant Polycystic Kidney Disease

(2014) Robert W. Schrier et al.   NEW ENGLAND JOURNAL OF MEDICINE

Angiotensin Blockade in Late Autosomal Dominant Polycystic Kidney Disease

(2014) Vicente E. Torres et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bap1is essential for kidney function and cooperates withVhlin renal tumorigenesis

(2014) Shan-Shan Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nedd9 restrains renal cystogenesis in Pkd1-/- mice

(2014) A. S. Nikonova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms of regulated necrosis

(2014) Lorenzo Galluzzi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Pkd1 Regulates Lymphatic Vascular Morphogenesis during Development

(2014) Baptiste Coxam et al.   Cell Reports

Polycystin Signaling Is Required for Directed Endothelial Cell Migration and Lymphatic Development

(2014) Patricia Outeda et al.   Cell Reports

New Insights into Mechanisms Controlling the NLRP3 Inflammasome and Its Role in Lung Disease

(2013) Dominic De Nardo et al.   AMERICAN JOURNAL OF PATHOLOGY

The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia

(2013) John R. Srigley et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Tight junction proteins: From barrier to tumorigenesis

(2013) E. Aaron Runkle et al.   CANCER LETTERS

The Planar Cell Polarity Pathway Drives Pathogenesis of Chronic Lymphocytic Leukemia by the Regulation of B-Lymphocyte Migration

(2013) M. Kaucka et al.   CANCER RESEARCH

HDAC6 Inhibition Restores Ciliary Expression and Decreases Tumor Growth

(2013) S. A. Gradilone et al.   CANCER RESEARCH

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Survivin-Induced Abnormal Ploidy Contributes to Cystic Kidney and Aneurysm Formation

(2013) Wissam A. AbouAlaiwi et al.   CIRCULATION

Therapeutic strategies impacting cancer cell glutamine metabolism

(2013) Michael J Lukey et al.   Future Medicinal Chemistry

Clinical and pathological impact ofVHL, PBRM1, BAP1, SETD2, KDM6A, andJARID1cin clear cell renal cell carcinoma

(2013) Lucy Gossage et al.   GENES CHROMOSOMES & CANCER

Genome-wide methylation profiling of ADPKD identified epigenetically regulated genes associated with renal cyst development

(2013) Yu Mi Woo et al.   HUMAN GENETICS

Na-K-2Cl cotransporter and aquaporin 1 in arachnoid granulations, meningiomas, and meningiomas invading dura

(2013) Mahlon D. Johnson et al.   HUMAN PATHOLOGY

Genetic clonal mapping of in situ and invasive ductal carcinoma indicates the field cancerization phenomenon in the breast

(2013) Maria P. Foschini et al.   HUMAN PATHOLOGY

Presence of primary cilia in cancer cells correlates with prognosis of pancreatic ductal adenocarcinoma

(2013) Katsura Emoto et al.   HUMAN PATHOLOGY

Emerging Roles of Claudins in Human Cancer

(2013) Mi Kwon   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Local cAMP signaling in disease at a glance

(2013) M. G. Gold et al.   JOURNAL OF CELL SCIENCE

Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease

(2013) Xia Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Genomic instability in patients with autosomal-dominant polycystic kidney disease

(2013) Ming Li et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Smac-Mimetic-Induced Epithelial Cell Death Reduces the Growth of Renal Cysts

(2013) L. X. Fan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Type of PKD1 Mutation Influences Renal Outcome in ADPKD

(2013) E. Cornec-Le Gall et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Targeting of sodium–glucose cotransporters with phlorizin inhibits polycystic kidney disease progression in Han:SPRD rats

(2013) Xueqi Wang et al.   KIDNEY INTERNATIONAL

Macrophages promote polycystic kidney disease progression

(2013) Katherine I Swenson-Fields et al.   KIDNEY INTERNATIONAL

Periostin promotes renal cyst growth and interstitial fibrosis in polycystic kidney disease

(2013) Darren P. Wallace et al.   KIDNEY INTERNATIONAL

NEK8 Links the ATR-Regulated Replication Stress Response and S Phase CDK Activity to Renal Ciliopathies

(2013) Hyo Jei Claudia Choi et al.   MOLECULAR CELL

Comprehensive molecular characterization of clear cell renal cell carcinoma

(2013)   NATURE

Functional interaction between autophagy and ciliogenesis

(2013) Olatz Pampliega et al.   NATURE

Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites

(2013) Zaiming Tang et al.   NATURE

Integrated molecular analysis of clear-cell renal cell carcinoma

(2013) Yusuke Sato et al.   NATURE GENETICS

Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease

(2013) Ming Ma et al.   NATURE GENETICS

Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy

(2013) Isaline Rowe et al.   NATURE MEDICINE

Sorting out functions of sirtuins in cancer

(2013) M Roth et al.   ONCOGENE

Lack of claudin-7 is a strong predictor of regional recurrence in oral and oropharyngeal squamous cell carcinoma

(2013) L.J. Melchers et al.   ORAL ONCOLOGY

Primary Cilia Are Lost in Preinvasive and Invasive Prostate Cancer

(2013) Nadia B. Hassounah et al.   PLoS One

Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease

(2013) T. Seeger-Nukpezah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polycystic Kidney Disease: A Case of Suppressed Autophagy?

(2013) Kameswaran Ravichandran et al.   SEMINARS IN NEPHROLOGY

Diagnosis and treatment of cystic renal cell carcinoma

(2013) Jiexiu Zhang et al.   World Journal of Surgical Oncology

KCa3.1 channels are involved in the infiltrative behavior of glioblastoma in vivo

(2013) G D'Alessandro et al.   Cell Death & Disease

Foretinib (XL880): c-MET Inhibitor with Activity in Papillary Renal Cell Cancer

(2013) Theodore F. Logan   Current Oncology Reports

Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis

(2013) Maddalena Castelli et al.   Nature Communications

Wnt and planar cell polarity signaling in cystic renal disease

(2013) Paraskevi Goggolidou   Organogenesis

Wdpcp, a PCP Protein Required for Ciliogenesis, Regulates Directional Cell Migration and Cell Polarity by Direct Modulation of the Actin Cytoskeleton

(2013) Cheng Cui et al.   PLOS BIOLOGY

Novel tyrosine kinase inhibitors for renal cell carcinoma

(2013) Tanya B Dorff et al.   Expert Review of Clinical Pharmacology

Claudins and the Kidney

(2012) Jianghui Hou et al.   Annual Review of Physiology

Spectrum of Preneoplastic and Neoplastic Cystic Lesions of the Kidney

(2012) Ying-Bei Chen et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration

(2012) Valbona Luga et al.   CELL

Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response Signaling

(2012) Moumita Chaki et al.   CELL

Chromosome instability and deregulated proliferation: an unavoidable duo

(2012) Courtney H. Coschi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies

(2012) Junmin Pan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Aurora A kinase (AURKA) in normal and pathological cell division

(2012) Anna S. Nikonova et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular Pathways: The Role of Primary Cilia in Cancer Progression and Therapeutics with a Focus on Hedgehog Signaling

(2012) N. B. Hassounah et al.   CLINICAL CANCER RESEARCH

Oncogene addiction

(2012) Jeffrey Settleman   CURRENT BIOLOGY

The extracellular matrix and ciliary signaling

(2012) Tamina Seeger-Nukpezah et al.   CURRENT OPINION IN CELL BIOLOGY

Autosomal dominant polycystic kidney disease: Comprehensive mutation analysis of PKD1 and PKD2 in 700 unrelated patients

(2012) Marie-Pierre Audrézet et al.   HUMAN MUTATION

Tg737 signaling is required for hypoxia-enhanced invasion and migration of hepatoma cells

(2012) Nan You et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Disruption of IFT Complex A Causes Cystic Kidneys without Mitotic Spindle Misorientation

(2012) J. A. Jonassen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Kidney Injury Accelerates Cystogenesis via Pathways Modulated by Heme Oxygenase and Complement

(2012) J. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits

(2012) Hong Liu et al.   NATURE CELL BIOLOGY

BAP1 loss defines a new class of renal cell carcinoma

(2012) Samuel Peña-Llopis et al.   NATURE GENETICS

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease

(2012) Vicente E. Torres et al.   NEW ENGLAND JOURNAL OF MEDICINE

CFTR suppresses tumor progression through miR-193b targeting urokinase plasminogen activator (uPA) in prostate cancer

(2012) C Xie et al.   ONCOGENE

Cell polarity and cystic kidney disease

(2012) Sorin Fedeles et al.   PEDIATRIC NEPHROLOGY

The VHL/HIF axis in clear cell renal carcinoma

(2012) Chuan Shen et al.   SEMINARS IN CANCER BIOLOGY

New aspects of the Warburg effect in cancer cell biology

(2012) Steven J. Bensinger et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Regulation of Brain Tumor Dispersal by NKCC1 Through a Novel Role in Focal Adhesion Regulation

(2012) Tomas Garzon-Muvdi et al.   PLOS BIOLOGY

Meta-Analysis of Randomized Controlled Trials on Effect of Angiotensin-Converting Enzyme Inhibitors on Cancer Risk

(2011) Ilke Sipahi et al.   AMERICAN JOURNAL OF CARDIOLOGY

c-Src inactivation reduces renal epithelial cell-matrix adhesion, proliferation, and cyst formation

(2011) Justine Elliott et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Apico-basal polarity in polycystic kidney disease epithelia

(2011) Patricia D. Wilson   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Apoptosis in polycystic kidney disease

(2011) Béatrice Goilav   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Fluid transport and cystogenesis in autosomal dominant polycystic kidney disease

(2011) Sara Terryn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Fibrosis and progression of Autosomal Dominant Polycystic Kidney Disease (ADPKD)

(2011) Jill Norman   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The level of claudin-7 is reduced as an early event in colorectal carcinogenesis

(2011) Jette Bornholdt et al.   BMC CANCER

Targeting the extrinsic apoptosis signaling pathway for cancer therapy

(2011) Thomas J. Sayers   CANCER IMMUNOLOGY IMMUNOTHERAPY

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Cilia and cell cycle re-entry

(2011) Sehyun Kim et al.   CELL CYCLE

Inversin, Wnt signaling and primary cilia

(2011) Soeren Lienkamp et al.   DIFFERENTIATION

Germline PKHD1 mutations are protective against colorectal cancer

(2011) Christopher J. Ward et al.   HUMAN GENETICS

NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway

(2011) Sandra Habbig et al.   JOURNAL OF CELL BIOLOGY

Mitotic spindle misorientation in cancer - out of alignment and into the fire

(2011) J. C. Pease et al.   JOURNAL OF CELL SCIENCE

PET Imaging of Glutaminolysis in Tumors by 18F-(2S,4R)4-Fluoroglutamine

(2011) B. P. Lieberman et al.   JOURNAL OF NUCLEAR MEDICINE

Macrophages Promote Cyst Growth in Polycystic Kidney Disease

(2011) A. Karihaloo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The canonical Wnt signaling pathway is not involved in renal cyst development in the kidneys of inv mutant mice

(2011) Noriyuki Sugiyama et al.   KIDNEY INTERNATIONAL

Inhibition of histone deacetylases targets the transcription regulator Id2 to attenuate cystic epithelial cell proliferation

(2011) Lucy X. Fan et al.   KIDNEY INTERNATIONAL

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

(2011) Ignacio Varela et al.   NATURE

The cilia protein IFT88 is required for spindle orientation in mitosis

(2011) Benedicte Delaval et al.   NATURE CELL BIOLOGY

Why kidneys fail in autosomal dominant polycystic kidney disease

(2011) Jared J. Grantham et al.   Nature Reviews Nephrology

Changes in causes of death and risk of cancer in Danish patients with autosomal dominant polycystic kidney disease and end-stage renal disease

(2011) B. Orskov et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Mechanism-Based Therapeutics for Autosomal Dominant Polycystic Kidney Disease: Recent Progress and Future Prospects

(2011) Ming-Yang Chang et al.   NEPHRON CLINICAL PRACTICE

Ciliopathies

(2011) Friedhelm Hildebrandt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis

(2011) V. Takiar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Advances in Autosomal Dominant Polycystic Kidney Disease

(2010) Anna Rachel Gallagher et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Extrarenal Manifestations of Autosomal Dominant Polycystic Kidney Disease

(2010) Yves Pirson   ADVANCES IN CHRONIC KIDNEY DISEASE

VHL-gene Deletion in Single Renal Tubular Epithelial Cells and Renal Tubular Cysts: Further Evidence for a Cyst-dependent Progression Pathway of Clear Cell Renal Carcinoma in von Hippel-Lindau Disease

(2010) Matteo Montani et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Cyclic AMP-mediated cyst expansion

(2010) Darren P. Wallace   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Histone Methyltransferase Gene SETD2 Is a Novel Tumor Suppressor Gene in Clear Cell Renal Cell Carcinoma

(2010) Gerben Duns et al.   CANCER RESEARCH

Human Enhancer of Filamentation 1 Is a Mediator of Hypoxia-Inducible Factor-1 -Mediated Migration in Colorectal Carcinoma Cells

(2010) S. H. Kim et al.   CANCER RESEARCH

Inhibition of the Sodium-Potassium-Chloride Cotransporter Isoform-1 Reduces Glioma Invasion

(2010) B. R. Haas et al.   CANCER RESEARCH

The Hippo Pathway Regulates Wnt/β-Catenin Signaling

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation

(2010) Wissam A. AbouAlaiwi et al.   HUMAN MOLECULAR GENETICS

Polycystin-1 Protein Level Determines Activity of the Gα12/JNK Apoptosis Pathway

(2010) Wanfeng Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cell biology of polycystic kidney disease

(2010) Hannah C. Chapin et al.   JOURNAL OF CELL BIOLOGY

Rapamycin Ameliorates PKD Resulting from Conditional Inactivation of Pkd1

(2010) J. M. Shillingford et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

VHL Inactivation Induces HEF1 and Aurora Kinase A

(2010) J. Xu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Aberrant Regulation of Planar Cell Polarity in Polycystic Kidney Disease

(2010) A. Luyten et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Angiogenic growth factors correlate with disease severity in young patients with autosomal dominant polycystic kidney disease

(2010) Berenice Y. Reed et al.   KIDNEY INTERNATIONAL

Primary cilia regulate mTORC1 activity and cell size through Lkb1

(2010) Christopher Boehlke et al.   NATURE CELL BIOLOGY

Sirolimus and Kidney Growth in Autosomal Dominant Polycystic Kidney Disease

(2010) Andreas L. Serra et al.   NEW ENGLAND JOURNAL OF MEDICINE

Everolimus in Patients with Autosomal Dominant Polycystic Kidney Disease

(2010) Gerd Walz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Analysis of VHL Gene Alterations and their Relationship to Clinical Parameters in Sporadic Conventional Renal Cell Carcinoma

(2009) A. C. Young et al.   CLINICAL CANCER RESEARCH

Renal Cystic Diseases and Renal Neoplasms: A Mini-Review

(2009) S. M. Bonsib   Clinical Journal of the American Society of Nephrology

Renal injury is a third hit promoting rapid development of adult polycystic kidney disease

(2009) Ayumi Takakura et al.   HUMAN MOLECULAR GENETICS

Genetic Basis of Bilateral Renal Cancer: Implications for Evaluation and Management

(2009) W. Marston Linehan   JOURNAL OF CLINICAL ONCOLOGY

The von Hippel Lindau Tumor Suppressor Limits Longevity

(2009) R.-U. Muller et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Pkd1 Haploinsufficiency Increases Renal Damage and Induces Microcyst Formation following Ischemia/Reperfusion

(2009) A. P. Bastos et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Loss of Oriented Cell Division Does not Initiate Cyst Formation

(2009) S. Nishio et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Autosomal dominant polycystic kidney disease: the last 3 years

(2009) Vicente E. Torres et al.   KIDNEY INTERNATIONAL

Impaired Wnt–β-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy

(2009) Madeline A Lancaster et al.   NATURE MEDICINE

Dual and opposing roles of primary cilia in medulloblastoma development

(2009) Young-Goo Han et al.   NATURE MEDICINE

Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models

(2009) Y. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteasomal Regulation of the Hypoxic Response Modulates Aging in C. elegans

(2009) R. Mehta et al.   SCIENCE

Prevalence of Renal Cell Carcinoma in Patients With Autosomal Dominant Polycystic Kidney Disease and Chronic Renal Failure

(2009) Pascal Hajj et al.   UROLOGY

TGF-β Mediated Epithelial-Mesenchymal Transition in Autosomal Dominant Polycystic Kidney Disease

(2009) Seung Wan Chea et al.   YONSEI MEDICAL JOURNAL

Cell Cycle-Dependent Ciliogenesis and Cancer

(2008) O. V. Plotnikova et al.   CANCER RESEARCH

Improved Identification of von Hippel-Lindau Gene Alterations in Clear Cell Renal Tumors

(2008) M. L. Nickerson et al.   CLINICAL CANCER RESEARCH

pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation

(2008) Ian J Frew et al.   EMBO JOURNAL

An Unexpected Role for Ion Channels in Brain Tumor Metastasis

(2008) Harald Sontheimer   EXPERIMENTAL BIOLOGY AND MEDICINE

Loss of polycystin-1 causes centrosome amplification and genomic instability

(2008) Lorenzo Battini et al.   HUMAN MOLECULAR GENETICS

Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia

(2008) Vishal Patel et al.   HUMAN MOLECULAR GENETICS

Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1

(2008) Sekiya Shibazaki et al.   HUMAN MOLECULAR GENETICS

Claudin-7 and claudin-8: immunohistochemical markers for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma

(2008) Adeboye O. Osunkoya et al.   HUMAN PATHOLOGY

Aquaporins—new players in cancer biology

(2008) A. S. Verkman et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Tight junction composition is altered in the epithelium of polycystic kidneys

(2008) ASL Yu et al.   JOURNAL OF PATHOLOGY

Src Inhibition Ameliorates Polycystic Kidney Disease

(2008) W. E. Sweeney et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Let's look at cysts from both sides now

(2008) Seth L. Alper   KIDNEY INTERNATIONAL

Sporadic clear cell renal cell carcinoma but not the papillary type is characterized by severely reduced frequency of primary cilia

(2008) Peter Schraml et al.   MODERN PATHOLOGY

Regulation of Renal Epithelial Tight Junctions by the von Hippel-Lindau Tumor Suppressor Gene Involves Occludin and Claudin 1 and Is Independent of E-Cadherin

(2008) Sarah K. Harten et al.   MOLECULAR BIOLOGY OF THE CELL

VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400

(2008) Arthur P. Young et al.   NATURE CELL BIOLOGY

A tumor necrosis factor-α–mediated pathway promoting autosomal dominant polycystic kidney disease

(2008) Xiaogang Li et al.   NATURE MEDICINE

Autosomal Dominant Polycystic Kidney Disease

(2008) Jared J. Grantham   NEW ENGLAND JOURNAL OF MEDICINE

Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57KIP2and Cdk2

(2008) Kyriacos N Felekkis et al.   BMC Nephrology

Mechanisms of Field Cancerization in the Human Stomach: The Expansion and Spread of Mutated Gastric Stem Cells

(2007) Stuart A.C. McDonald et al.   GASTROENTEROLOGY

Overexpression of innate immune response genes in a model of recessive polycystic kidney disease

(2007) M. Mrug et al.   KIDNEY INTERNATIONAL