Why the impact of mechanical stimuli on stem cells remains a challenge
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Why the impact of mechanical stimuli on stem cells remains a challenge
Authors
Keywords
Biomaterials, Epigenetic, Embryonic stem cells, Hydrogels, Induced pluripotent stem cells, iPSC, Matrix, Mesenchymal stromal cells, Mechanobiology, Soft
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2018-05-05
DOI
10.1007/s00018-018-2830-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Does soft really matter? Differentiation of induced pluripotent stem cells into mesenchymal stromal cells is not influenced by soft hydrogels
- (2018) Roman Goetzke et al. BIOMATERIALS
- β1 integrin–dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin
- (2017) Hiba Sabra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oscillatory fluid flow induces the osteogenic lineage commitment of mesenchymal stem cells: The effect of shear stress magnitude, frequency, and duration
- (2017) Elena Stavenschi et al. JOURNAL OF BIOMECHANICS
- Magnitude-dependent and inversely-related osteogenic/chondrogenic differentiation of human mesenchymal stem cells under dynamic compressive strain
- (2017) Christopher B. Horner et al. Journal of Tissue Engineering and Regenerative Medicine
- Mechanical forces direct stem cell behaviour in development and regeneration
- (2017) Kyle H. Vining et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- An Injectable Hybrid Hydrogel with Oriented Short Fibers Induces Unidirectional Growth of Functional Nerve Cells
- (2017) Abdolrahman Omidinia-Anarkoli et al. Small
- Xeno-free culture of human pluripotent stem cells on oligopeptide-grafted hydrogels with various molecular designs
- (2017) Yen-Ming Chen et al. Scientific Reports
- Surface Topography Guides Morphology and Spatial Patterning of Induced Pluripotent Stem Cell Colonies
- (2017) Giulio Abagnale et al. Stem Cell Reports
- Genotoxic Effects of Culture Media on Human Pluripotent Stem Cells
- (2017) Megha Prakash Bangalore et al. Scientific Reports
- Nanotopological plate stimulates osteogenic differentiation through TAZ activation
- (2017) Jun-Ha Hwang et al. Scientific Reports
- Three-Dimensional Polydopamine Functionalized Coiled Microfibrous Scaffolds Enhance Human Mesenchymal Stem Cells Colonization and Mild Myofibroblastic Differentiation
- (2016) Mehmet Berat Taskin et al. ACS Applied Materials & Interfaces
- The impact of microgravity on bone in humans
- (2016) Daniela Grimm et al. BONE
- Mechanical signals promote osteogenic fate through a primary cilia-mediated mechanism
- (2016) Julia C. Chen et al. FASEB JOURNAL
- In vitro cyclic compressive loads potentiate early osteogenic events in engineered bone tissue
- (2016) Akhilandeshwari Ravichandran et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
- Nuclear transport of paxillin depends on focal adhesion dynamics and FAT domains
- (2016) Aneesh R. Sathe et al. JOURNAL OF CELL SCIENCE
- Defined three-dimensional microenvironments boost induction of pluripotency
- (2016) Massimiliano Caiazzo et al. NATURE MATERIALS
- Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction
- (2016) Zhen-Ning Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamics of Mechanosensitive Neural Stem Cell Differentiation
- (2016) Sebastian Rammensee et al. STEM CELLS
- Functional Maturation of Induced Pluripotent Stem Cell Hepatocytes in Extracellular Matrix-A Comparative Analysis of Bioartificial Liver Microenvironments
- (2016) Bo Wang et al. Stem Cells Translational Medicine
- Identification of polymer surface adsorbed proteins implicated in pluripotent human embryonic stem cell expansion
- (2016) Moamen Hammad et al. Biomaterials Science
- Epigenetic Classification of Human Mesenchymal Stromal Cells
- (2016) Danilo Candido de Almeida et al. Stem Cell Reports
- Surface Curvature Differentially Regulates Stem Cell Migration and Differentiation via Altered Attachment Morphology and Nuclear Deformation
- (2016) Maike Werner et al. Advanced Science
- Three-dimensional spherical spatial boundary conditions differentially regulate osteogenic differentiation of mesenchymal stromal cells
- (2016) Yin-Ping Lo et al. Scientific Reports
- Mechanical stretch endows mesenchymal stem cells stronger angiogenic and anti-apoptotic capacities via NFκB activation
- (2015) Zhuoli Zhu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Surface topography enhances differentiation of mesenchymal stem cells towards osteogenic and adipogenic lineages
- (2015) Giulio Abagnale et al. BIOMATERIALS
- Arterial specification of endothelial cells derived from human induced pluripotent stem cells in a biomimetic flow bioreactor
- (2015) Amogh Sivarapatna et al. BIOMATERIALS
- On human pluripotent stem cell control: The rise of 3D bioengineering and mechanobiology
- (2015) Yue Shao et al. BIOMATERIALS
- Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments
- (2015) Brendon M. Baker et al. NATURE MATERIALS
- Hydrogels with tunable stress relaxation regulate stem cell fate and activity
- (2015) Ovijit Chaudhuri et al. NATURE MATERIALS
- microRNA-21 Mediates Stretch-Induced Osteogenic Differentiation in Human Periodontal Ligament Stem Cells
- (2015) Fulan Wei et al. STEM CELLS AND DEVELOPMENT
- Substrate stress relaxation regulates cell spreading
- (2015) Ovijit Chaudhuri et al. Nature Communications
- hiPS-MSCs differentiation towards fibroblasts on a 3D ECM mimicking scaffold
- (2015) Ruodan Xu et al. Scientific Reports
- Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin
- (2015) Sabine Pellett et al. Scientific Reports
- Bridging the Gap: From 2D Cell Culture to 3D Microengineered Extracellular Matrices
- (2015) Yanfen Li et al. Advanced Healthcare Materials
- Expression of α-Smooth Muscle Actin Determines the Fate of Mesenchymal Stromal Cells
- (2015) Nilesh P. Talele et al. Stem Cell Reports
- Matrix elasticity, replicative senescence and DNA methylation patterns of mesenchymal stem cells
- (2014) Anne Schellenberg et al. BIOMATERIALS
- Creating polymer hydrogel microfibres with internal alignment via electrical and mechanical stretching
- (2014) Shuming Zhang et al. BIOMATERIALS
- The effect of cyclic stretch on maturation and 3D tissue formation of human embryonic stem cell-derived cardiomyocytes
- (2014) Anton Mihic et al. BIOMATERIALS
- Primary Cilia Exist in a Small Fraction of Cells in Trabecular Bone and Marrow
- (2014) Thomas R. Coughlin et al. CALCIFIED TISSUE INTERNATIONAL
- Evaluation of human platelet lysate versus fetal bovine serum for culture of mesenchymal stromal cells
- (2014) Hatim Hemeda et al. CYTOTHERAPY
- Materials as stem cell regulators
- (2014) William L. Murphy et al. NATURE MATERIALS
- Mechanical memory and dosing influence stem cell fate
- (2014) Chun Yang et al. NATURE MATERIALS
- Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation
- (2014) J. E. Dixon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 3D niche microarrays for systems-level analyses of cell fate
- (2014) A. Ranga et al. Nature Communications
- Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytes
- (2014) Renjun Zhu et al. Stem Cell Research & Therapy
- Aging of blood can be tracked by DNA methylation changes at just three CpG sites
- (2014) Carola Weidner et al. GENOME BIOLOGY
- Epigenetic Rejuvenation of Mesenchymal Stromal Cells Derived from Induced Pluripotent Stem Cells
- (2014) Joana Frobel et al. Stem Cell Reports
- Biophysically Defined and Cytocompatible Covalently Adaptable Networks as Viscoelastic 3D Cell Culture Systems
- (2013) Daniel D. McKinnon et al. ADVANCED MATERIALS
- mTORC2 Regulates Mechanically Induced Cytoskeletal Reorganization and Lineage Selection in Marrow-Derived Mesenchymal Stem Cells
- (2013) Buer Sen et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Mesenchymal stem cell mechanobiology and emerging experimental platforms
- (2013) L. MacQueen et al. Journal of the Royal Society Interface
- Responsive biomimetic networks from polyisocyanopeptide hydrogels
- (2013) Paul H. J. Kouwer et al. NATURE
- Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
- (2013) J. Swift et al. SCIENCE
- A thermoresponsive and chemically defined hydrogel for long-term culture of human embryonic stem cells
- (2013) Rong Zhang et al. Nature Communications
- Regulation of the fate of human mesenchymal stem cells by mechanical and stereo-topographical cues provided by silicon nanowires
- (2012) Shu-Wen Kuo et al. BIOMATERIALS
- The significance of integrin ligand nanopatterning on lipid raft clustering in hematopoietic stem cells
- (2012) Eva Altrock et al. BIOMATERIALS
- Pluripotent stem cells escape from senescence-associated DNA methylation changes
- (2012) C. M. Koch et al. GENOME RESEARCH
- Lateral spacing of adhesion peptides influences human mesenchymal stem cell behaviour
- (2012) J. E. Frith et al. JOURNAL OF CELL SCIENCE
- Modelling human embryoid body cell adhesion to a combinatorial library of polymer surfaces
- (2012) V. Chandana Epa et al. JOURNAL OF MATERIALS CHEMISTRY
- Integrinα4 impacts on differential adhesion of preadipocytes and stem cells on synthetic polymers
- (2012) Mareike Hoss et al. Journal of Tissue Engineering and Regenerative Medicine
- An innovative stand-alone bioreactor for the highly reproducible transfer of cyclic mechanical stretch to stem cells cultured in a 3D scaffold
- (2012) Marco Govoni et al. Journal of Tissue Engineering and Regenerative Medicine
- Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators
- (2012) Laura M. Hoffman et al. MOLECULAR BIOLOGY OF THE CELL
- Extracellular-matrix tethering regulates stem-cell fate
- (2012) Britta Trappmann et al. NATURE MATERIALS
- Primary Cilia-Mediated Mechanotransduction in Human Mesenchymal Stem Cells
- (2012) David A. Hoey et al. STEM CELLS
- Insights into the Role of Focal Adhesion Modulation in Myogenic Differentiation of Human Mesenchymal Stem Cells
- (2012) Haiyang Yu et al. STEM CELLS AND DEVELOPMENT
- Human Platelet Lysate Gel Provides a Novel Three Dimensional-Matrix for Enhanced Culture Expansion of Mesenchymal Stromal Cells
- (2012) Gudrun Walenda et al. TISSUE ENGINEERING PART C-METHODS
- Stiffening hydrogels to probe short- and long-term cellular responses to dynamic mechanics
- (2012) Murat Guvendiren et al. Nature Communications
- The use of mesenchymal stem cells in tissue engineering
- (2012) Andrew J. Rosenbaum et al. Organogenesis
- Engineering the Regenerative Microenvironment with Biomaterials
- (2012) Jeffrey J. Rice et al. Advanced Healthcare Materials
- Mechanical stimulation of cyclic tensile strain induces reduction of pluripotent related gene expressions via activation of Rho/ROCK and subsequent decreasing of AKT phosphorylation in human induced pluripotent stem cells
- (2011) Takeshi Teramura et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- RhoA/ROCK, cytoskeletal dynamics, and focal adhesion kinase are required for mechanical stretch-induced tenogenic differentiation of human mesenchymal stem cells
- (2011) Baiyao Xu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- Artificial niche microarrays for probing single stem cell fate in high throughput
- (2011) Samy Gobaa et al. NATURE METHODS
- Stiffness Gradients Mimicking In Vivo Tissue Variation Regulate Mesenchymal Stem Cell Fate
- (2011) Justin R. Tse et al. PLoS One
- An algorithm-based topographical biomaterials library to instruct cell fate
- (2011) H. V. Unadkat et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity
- (2011) J. Du et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanically Induced Focal Adhesion Assembly Amplifies Anti-Adipogenic Pathways in Mesenchymal Stem Cells
- (2011) Buer Sen et al. STEM CELLS
- The ground state of pluripotency
- (2010) Jason Wray et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2
- (2010) J. Patterson et al. BIOMATERIALS
- The influence of biological motifs and dynamic mechanical stimulation in hydrogel scaffold systems on the phenotype of chondrocytes
- (2010) Taly P. Appelman et al. BIOMATERIALS
- Matrix stiffness regulation of integrin-mediated mechanotransduction during osteogenic differentiation of human mesenchymal stem cells
- (2010) Yu-Ru V Shih et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells
- (2010) Ying Mei et al. NATURE MATERIALS
- Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate
- (2010) Nathaniel Huebsch et al. NATURE MATERIALS
- Geometric cues for directing the differentiation of mesenchymal stem cells
- (2010) K. A. Kilian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture
- (2010) P. M. Gilbert et al. SCIENCE
- The Effect of Simulated Microgravity on Human Mesenchymal Stem Cells Cultured in an Osteogenic Differentiation System: A Bioinformatics Study
- (2010) Dima Sheyn et al. TISSUE ENGINEERING PART A
- Different Facets of Aging in Human Mesenchymal Stem Cells
- (2010) Wolfgang Wagner et al. TISSUE ENGINEERING PART B-REVIEWS
- Understanding the effect of mean pore size on cell activity in collagen-glycosaminoglycan scaffolds
- (2010) Ciara M. Murphy et al. Cell Adhesion & Migration
- Hydrogels in Regenerative Medicine
- (2009) Brandon V. Slaughter et al. ADVANCED MATERIALS
- The effects of dynamic and three-dimensional environments on chondrogenic differentiation of bone marrow stromal cells
- (2009) Youngmee Jung et al. Biomedical Materials
- Control of Stem Cell Fate by Physical Interactions with the Extracellular Matrix
- (2009) Farshid Guilak et al. Cell Stem Cell
- Effect of growth media and serum replacements on the proliferation and differentiation of adipose-derived stem cells
- (2009) Pia Lund et al. CYTOTHERAPY
- Effect of fluid flow-induced shear stress on human mesenchymal stem cells: Differential gene expression of IL1B and MAP3K8 in MAPK signaling
- (2009) John R. Glossop et al. GENE EXPRESSION PATTERNS
- Priming integrin 5 promotes human mesenchymal stromal cell osteoblast differentiation and osteogenesis
- (2009) Z. Hamidouche et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stem cell fate dictated solely by altered nanotube dimension
- (2009) S. Oh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Growth Factors, Matrices, and Forces Combine and Control Stem Cells
- (2009) D. E. Discher et al. SCIENCE
- Species Variation in the Mechanisms of Mesenchymal Stem Cell-Mediated Immunosuppression
- (2009) Guangwen Ren et al. STEM CELLS
- Identification of Distinct Topographical Surface Microstructures Favoring Either Undifferentiated Expansion or Differentiation of Murine Embryonic Stem Cells
- (2009) Lotte D’Andrea Markert et al. STEM CELLS AND DEVELOPMENT
- Effect of hydrogel porosity on marrow stromal cell phenotypic expression
- (2008) Mahrokh Dadsetan et al. BIOMATERIALS
- The differential effect of scaffold composition and architecture on chondrocyte response to mechanical stimulation
- (2008) Taly P. Appelman et al. BIOMATERIALS
- Heterogeneity of mesenchymal stromal cell preparations
- (2008) A.D. Ho et al. CYTOTHERAPY
- Scaffolding in tissue engineering: general approaches and tissue-specific considerations
- (2008) B. P. Chan et al. EUROPEAN SPINE JOURNAL
- Pluripotent stem cell lines
- (2008) J. Yu et al. GENES & DEVELOPMENT
- Effects of Hindlimb Unloading on Ex Vivo Growth and Osteogenic/Adipogenic Potentials of Bone Marrow-Derived Mesenchymal Stem Cells in Rats
- (2008) Zhijun Pan et al. STEM CELLS AND DEVELOPMENT
- Assessment of stem cell/biomaterial combinations for stem cell-based tissue engineering
- (2007) Sabine Neuss et al. BIOMATERIALS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now