Defined three-dimensional microenvironments boost induction of pluripotency

3D niche microarrays for systems-level analyses of cell fate

(2014) A. Ranga et al.   Nature Communications

Temporal Perturbation of the Wnt Signaling Pathway in the Control of Cell Reprogramming Is Modulated by TCF1

(2014) Francesco Aulicino et al.   Stem Cell Reports

Comparative Proteomic Analysis of Supportive and Unsupportive Extracellular Matrix Substrates for Human Embryonic Stem Cell Maintenance

(2013) Despina Soteriou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stem cells: Surf the waves of reprogramming

(2013) Ignacio Sancho-Martinez et al.   NATURE

Biophysical regulation of epigenetic state and cell reprogramming

(2013) Timothy L. Downing et al.   NATURE MATERIALS

A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation

(2013) Y. Lei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-term maintenance of mouse embryonic stem cell pluripotency by manipulating integrin signaling within 3D scaffolds without active Stat3

(2012) Seung Tae Lee et al.   BIOMATERIALS

A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells

(2012) Jose M. Polo et al.   CELL

Role of TAZ as Mediator of Wnt Signaling

(2012) Luca Azzolin et al.   CELL

E-cadherin and, in Its Absence, N-cadherin Promotes Nanog Expression in Mouse Embryonic Stem Cells via STAT3 Phosphorylation

(2012) Kate Hawkins et al.   STEM CELLS

Highly Coordinated Proteome Dynamics during Reprogramming of Somatic Cells to Pluripotency

(2012) Jenny Hansson et al.   Cell Reports

The roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generation

(2012) Ryan Schmidt et al.   GENOME BIOLOGY

Elucidating the Role of Matrix Stiffness in 3D Cell Migration and Remodeling

(2011) M. Ehrbar et al.   BIOPHYSICAL JOURNAL

Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network

(2011) Yen-Sin Ang et al.   CELL

Reprogramming Factor Expression Initiates Widespread Targeted Chromatin Remodeling

(2011) Richard P. Koche et al.   Cell Stem Cell

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts

(2010) Ronghui Li et al.   Cell Stem Cell

Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming

(2010) Payman Samavarchi-Tehrani et al.   Cell Stem Cell

The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

(2010) I. Lian et al.   GENES & DEVELOPMENT

An ES-Like Pluripotent State in FGF-Dependent Murine iPS cells

(2010) Bruno Di Stefano et al.   PLoS One

Engineering integrin signaling for promoting embryonic stem cell self-renewal in a precisely defined niche

(2009) Seung Tae Lee et al.   BIOMATERIALS

Transgenic mice with defined combinations of drug-inducible reprogramming factors

(2009) Styliani Markoulaki et al.   NATURE BIOTECHNOLOGY

Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stem cells

(2009) Farhan Chowdhury et al.   NATURE MATERIALS

EpCAM Is Involved in Maintenance of the Murine Embryonic Stem Cell Phenotype

(2009) Bárbara González et al.   STEM CELLS

The benefit of human embryonic stem cell encapsulation for prolonged feeder-free maintenance

(2008) Norhayati Siti-Ismail et al.   BIOMATERIALS

Wnt Signaling Promotes Reprogramming of Somatic Cells to Pluripotency

(2008) Alexander Marson et al.   Cell Stem Cell

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

(2008) Danwei Huangfu et al.   NATURE BIOTECHNOLOGY

Recombinant Vitronectin Is a Functionally Defined Substrate That Supports Human Embryonic Stem Cell Self-Renewal via αVβ5 Integrin

(2008) Stefan R. Braam et al.   STEM CELLS

Laminin-511 but Not -332, -111, or -411 Enables Mouse Embryonic Stem Cell Self-Renewal In Vitro

(2008) Anna Domogatskaya et al.   STEM CELLS