Pro-survival autophagy and cancer cell resistance to therapy

Autophagy Roles in the Modulation of DNA Repair Pathways

(2017) Luciana Gomes et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy enhanced the radioresistance of non-small cell lung cancer by regulating ROS level under hypoxia condition

(2017) Xiaoyan Chen et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Parkin-Independent Mitophagy Controls Chemotherapeutic Response in Cancer Cells

(2017) Elodie Villa et al.   Cell Reports

Egr-1 regulates irradiation-induced autophagy through Atg4B to promote radioresistance in hepatocellular carcinoma cells

(2017) W-x Peng et al.   Oncogenesis

Cucurbitacin E induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells

(2016) Guixin Ma et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Mechanisms of cisplatin resistance and targeting of cancer stem cells: Adding glycosylation to the equation

(2016) José Alexandre Ferreira et al.   DRUG RESISTANCE UPDATES

Inhibiting ROS-STAT3-dependent autophagy enhanced capsaicin–induced apoptosis in human hepatocellular carcinoma cells

(2016) Xun Chen et al.   FREE RADICAL RESEARCH

Stress management by autophagy: Implications for chemoresistance

(2016) Zhao Huang et al.   INTERNATIONAL JOURNAL OF CANCER

Autophagy Regulates Chromatin Ubiquitination in DNA Damage Response through Elimination of SQSTM1/p62

(2016) Yanan Wang et al.   MOLECULAR CELL

Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4 DDB2 E3 Ligase

(2016) Yongfei Yang et al.   MOLECULAR CELL

Autophagy in cancer metastasis

(2016) E E Mowers et al.   ONCOGENE

Aloe-emodin-mediated photodynamic therapy induces autophagy and apoptosis in human osteosarcoma cell line MG-63 through the ROS/JNK signaling pathway

(2016) PINGHUA TU et al.   ONCOLOGY REPORTS

The Protective Roles of ROS-Mediated Mitophagy on125I Seeds Radiation Induced Cell Death in HCT116 Cells

(2016) Lelin Hu et al.   Oxidative Medicine and Cellular Longevity

BRAFV600E inhibition stimulates AMP-activated protein kinase-mediated autophagy in colorectal cancer cells

(2016) Toshinori Sueda et al.   Scientific Reports

DNA Damage Response and Autophagy: A Meaningful Partnership

(2016) Aristides G. Eliopoulos et al.   Frontiers in Genetics

Radioresistance of Brain Tumors

(2016) Kevin Kelley et al.   Cancers

Autophagy positively regulates DNA damage recognition by nucleotide excision repair

(2015) Lei Qiang et al.   Autophagy

C/EBP homologous protein (CHOP) contributes to hepatocyte death via the promotion of ERO1α signalling in acute liver failure

(2015) Jianhua Rao et al.   BIOCHEMICAL JOURNAL

Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine

(2015) Claudia Fiorini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy inhibition re-sensitizes pulse stimulation-selected paclitaxel-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis

(2015) Jian Wen et al.   BREAST CANCER RESEARCH AND TREATMENT

The interplay between DNA repair and autophagy in cancer therapy

(2015) Dan Zhang et al.   CANCER BIOLOGY & THERAPY

Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells

(2015) Xiaopeng Yuan et al.   EXPERIMENTAL CELL RESEARCH

ROS/Autophagy/Nrf2 Pathway Mediated Low-Dose Radiation Induced Radio-Resistance in Human Lung Adenocarcinoma A549 Cell

(2015) Ni Chen et al.   International Journal of Biological Sciences

8-p-Hdroxybenzoyl Tovarol Induces Paraptosis Like Cell Death and Protective Autophagy in Human Cervical Cancer HeLa Cells

(2015) Cui Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The role for autophagy in cancer

(2015) Eileen White   JOURNAL OF CLINICAL INVESTIGATION

Pharmacologic screens reveal metformin that suppresses GRP78-dependent autophagy to enhance the anti-myeloma effect of bortezomib

(2015) S Jagannathan et al.   LEUKEMIA

Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine

(2015) Ming-Chen Yang et al.   Molecular Cancer

Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus

(2015) Keisuke Mochida et al.   NATURE

Cell death by autophagy: emerging molecular mechanisms and implications for cancer therapy

(2015) S Fulda et al.   ONCOGENE

Loss of autophagy causes a synthetic lethal deficiency in DNA repair

(2015) Emma Y. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asparaginase induces apoptosis and cytoprotective autophagy in chronic myeloid leukemia cells

(2015) Ping Song et al.   Oncotarget

Autophagy confers DNA damage repair pathways to protect the hematopoietic system from nuclear radiation injury

(2015) Weiwei Lin et al.   Scientific Reports

Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells

(2015) Hui-Mei Wu et al.   Scientific Reports

Roles of Autophagy Induced by Natural Compounds in Prostate Cancer

(2015) V. Naponelli et al.   Biomed Research International

Autophagy-related gene 12 (ATG12) is a novel determinant of primary resistance to HER2-targeted therapies: Utility of transcriptome analysis of the autophagy interactome to guide breast cancer treatment

(2015) Sílvia Cufí et al.   Oncotarget

Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway

(2015) Hongyu Zhou et al.   Oncotarget

Suppression of Chloride Channel 3 Expression Facilitates Sensitivity of Human Glioma U251 Cells to Cisplatin Through Concomitant Inhibition of Akt and Autophagy

(2014) Jing Su et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Autophagy and apoptosis: where do they meet?

(2014) Subhadip Mukhopadhyay et al.   APOPTOSIS

Over-Expression of Beclin-1 Facilitates Acquired Resistance to Histone Deacetylase Inhibitor-Induced Apoptosis

(2014) Shi-Miao Wang et al.   Asian Pacific Journal of Cancer Prevention

LAMP-2: A control step for phagosome and autophagosome maturation

(2014) Paul Saftig et al.   Autophagy

Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death

(2014) P Makhov et al.   BRITISH JOURNAL OF CANCER

Induction of autophagy contributes to crizotinib resistance in ALK-positive lung cancer

(2014) Cheng Ji et al.   CANCER BIOLOGY & THERAPY

Bortezomib induces protective autophagy through AMP-activated protein kinase activation in cultured pancreatic and colorectal cancer cells

(2014) Han Min et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Induction of autophagy counteracts the anticancer effect of cisplatin in human esophageal cancer cells with acquired drug resistance

(2014) Le Yu et al.   CANCER LETTERS

Dual role for CHOP in the crosstalk between autophagy and apoptosis to determine cell fate in response to amino acid deprivation

(2014) Wafa B'chir et al.   CELLULAR SIGNALLING

LAMP3 is involved in tamoxifen resistance in breast cancer cells through the modulation of autophagy

(2014) Anika Nagelkerke et al.   ENDOCRINE-RELATED CANCER

HCC cells with high levels of Bcl-2 are resistant to ABT-737 via activation of the ROS–JNK–autophagy pathway

(2014) Zhenhong Ni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells

(2014) XIU CHENG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Role of Autophagy in Cisplatin Resistance in Ovarian Cancer Cells

(2014) Juan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cucurbitacin I Induces Protective Autophagy in Glioblastomain Vitroandin Vivo

(2014) Guang Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An activation of LC3A-mediated autophagy contributes tode novoand acquired resistance to EGFR tyrosine kinase inhibitors in lung adenocarcinoma

(2014) Kaito Nihira et al.   JOURNAL OF PATHOLOGY

RAD6 Promotes Homologous Recombination Repair by Activating the Autophagy-Mediated Degradation of Heterochromatin Protein HP1

(2014) Su Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

Inhibition of Akt Reverses the Acquired Resistance to Sorafenib by Switching Protective Autophagy to Autophagic Cell Death in Hepatocellular Carcinoma

(2014) B. Zhai et al.   MOLECULAR CANCER THERAPEUTICS

Induction of autophagy contributes to cisplatin resistance in human ovarian cancer cells

(2014) LINGJIE BAO et al.   Molecular Medicine Reports

Temozolomide induces autophagy via ATM-AMPK-ULK1 pathways in glioma

(2014) YUHUI ZOU et al.   Molecular Medicine Reports

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CHOP mediates ASPP2-induced autophagic apoptosis in hepatoma cells by releasing Beclin-1 from Bcl-2 and inducing nuclear translocation of Bcl-2

(2014) K Liu et al.   Cell Death & Disease

Autophagy promotes paclitaxel resistance of cervical cancer cells: involvement of Warburg effect activated hypoxia-induced factor 1-α-mediated signaling

(2014) X Peng et al.   Cell Death & Disease

JNK confers 5-fluorouracil resistance in p53-deficient and mutant p53-expressing colon cancer cells by inducing survival autophagy

(2014) Xinbing Sui et al.   Scientific Reports

Blockade of Autophagy Aggravates Endoplasmic Reticulum Stress and Improves Paclitaxel Cytotoxicity in Human Cervical Cancer Cells

(2014) Li Xu et al.   Cancer Research and Treatment

Suppression of autophagy by chloroquine sensitizes 5-fluorouracil-mediated cell death in gallbladder carcinoma cells

(2014) Xiao Liang et al.   Cell and Bioscience

Autophagy Inhibition Promotes Gambogic Acid-induced Suppression of Growth and Apoptosis in Glioblastoma Cells

(2013) Guo-Xuan Luo et al.   Asian Pacific Journal of Cancer Prevention

DNA damage signaling triggers the cytoplasm-to-vacuole pathway of autophagy to regulate cell cycle progression

(2013) Vinay V. Eapen et al.   Autophagy

Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: Differences between primary and cancer cells

(2013) Jaganmohan Reddy Jangamreddy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma

(2013) J Shen et al.   BRITISH JOURNAL OF CANCER

Prognostic impact of Beclin 1, p62/sequestosome 1 and LC3 protein expression in colon carcinomas from patients receiving 5-fluorouracil as adjuvant chemotherapy

(2013) Jae Myung Park et al.   CANCER BIOLOGY & THERAPY

Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling

(2013) A Ko et al.   CELL DEATH AND DIFFERENTIATION

ERα-Targeted Therapy in Ovarian Cancer Cells by a Novel Estradiol-Platinum(II) Hybrid

(2013) K. Brasseur et al.   ENDOCRINOLOGY

Autophagy in the immune system

(2013) Daniel J. Puleston et al.   IMMUNOLOGY

Heat Shock Factor 1 (HSF1) Controls Chemoresistance and Autophagy through Transcriptional Regulation of Autophagy-related Protein 7 (ATG7)

(2013) Shruti Desai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Autophagy Inhibitor Chloroquine Overcomes the Innate Resistance of Wild-Type EGFR Non-Small-Cell Lung Cancer Cells to Erlotinib

(2013) Yiyu Zou et al.   Journal of Thoracic Oncology

Enhanced autophagy is required for survival in EGFR-independent EGFR-mutant lung adenocarcinoma cells

(2013) Yuji Sakuma et al.   LABORATORY INVESTIGATION

Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer

(2013) Yuan-yuan Li et al.   LUNG CANCER

CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis

(2013) Brian F. Teske et al.   MOLECULAR BIOLOGY OF THE CELL

Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer

(2013) Rebekah L Zinn et al.   Molecular Cancer

Enhanced autophagic flux by endoplasmic reticulum stress in human hepatocellular carcinoma cells contributes to the maintenance of cell viability

(2013) TAI MA et al.   ONCOLOGY REPORTS

Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1

(2013) D. N. Tripathi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Combination of Pterostilbene With Autophagy Inhibitors Exerts Efficient Apoptotic Characteristics in Both Chemosensitive and Chemoresistant Lung Cancer Cells

(2013) M.-J. Hsieh et al.   TOXICOLOGICAL SCIENCES

Hypoxia counteracts taxol-induced apoptosis in MDA-MB-231 breast cancer cells: role of autophagy and JNK activation

(2013) A Notte et al.   Cell Death & Disease

Perifosine induces protective autophagy and upregulation of ATG5 in human chronic myelogenous leukemia cells in vitro

(2012) Yin Tong et al.   ACTA PHARMACOLOGICA SINICA

Inhibition of autophagy-potentiated chemosensitivity to cisplatin in laryngeal cancer Hep-2 cells

(2012) Rong Kang et al.   AMERICAN JOURNAL OF OTOLARYNGOLOGY

Autophagy acts as a safeguard mechanism against G-quadruplex ligand-mediated DNA damage

(2012) Nicola Ivan Orlotti et al.   Autophagy

Ginsenoside F2 induces apoptosis accompanied by protective autophagy in breast cancer stem cells

(2012) Trang Thi Mai et al.   CANCER LETTERS

Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma

(2012) Y.-L. Hu et al.   CANCER RESEARCH

Benzyl isothiocyanate induces protective autophagy in human prostate cancer cells via inhibition of mTOR signaling

(2012) Ji-Fan Lin et al.   CARCINOGENESIS

Aspirin Inhibits mTOR Signaling, Activates AMP-Activated Protein Kinase, and Induces Autophagy in Colorectal Cancer Cells

(2012) Farhat V.N. Din et al.   GASTROENTEROLOGY

Oridonin Up-regulates Expression of P21 and Induces Autophagy and Apoptosis in Human Prostate Cancer Cells

(2012) Xiang Li et al.   International Journal of Biological Sciences

The dual PI3K/mTOR inhibitor NVP-BEZ235 and chloroquine synergize to trigger apoptosisviamitochondrial-lysosomal cross-talk

(2012) Christian Seitz et al.   INTERNATIONAL JOURNAL OF CANCER

Cancer and Radiation Therapy: Current Advances and Future Directions

(2012) Rajamanickam Baskar et al.   International Journal of Medical Sciences

Redox implications of AMPK-mediated signal transduction beyond energetic clues

(2012) S. Cardaci et al.   JOURNAL OF CELL SCIENCE

Inhibition of autophagy enhances anticancer effects of bevacizumab in hepatocarcinoma

(2012) Xian-ling Guo et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERK

(2012) A Avivar-Valderas et al.   ONCOGENE

Effect of dual inhibition of apoptosis and autophagy in prostate cancer

(2012) Ahamed Saleem et al.   PROSTATE

Monoclonal antibodies for the treatment of cancer

(2012) Casey W. Shuptrine et al.   SEMINARS IN CANCER BIOLOGY

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics

(2011) Tracey R. O’Donovan et al.   Autophagy

Autophagy protects breast cancer cells from epirubicin-induced apoptosis and facilitates epirubicin-resistance development

(2011) Wei-Liang Sun et al.   Autophagy

Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis

(2011) Ying-Hong Shi et al.   Autophagy

Role of autophagy in chemoresistance: Regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA–PKcs and PARP-1

(2011) Jung-Hoon Yoon et al.   BIOCHEMICAL PHARMACOLOGY

Autophagy inhibition enhances ursolic acid-induced apoptosis in PC3 cells

(2011) Seoung Woo Shin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Lysosomal Transmembrane Protein LAPTM4B Promotes Autophagy and Tolerance to Metabolic Stress in Cancer Cells

(2011) Y. Li et al.   CANCER RESEARCH

Adiponectin supports cell survival in glucose deprivation through enhancement of autophagic response in colorectal cancer cells

(2011) Baker S. Habeeb et al.   CANCER SCIENCE

Autophagy Activation in Hepatocellular Carcinoma Contributes to the Tolerance of Oxaliplatin via Reactive Oxygen Species Modulation

(2011) Z.-B. Ding et al.   CLINICAL CANCER RESEARCH

UV irradiation resistance-associated gene suppresses apoptosis by interfering with BAX activation

(2011) Xiaocheng Yin et al.   EMBO REPORTS

Autophagy and endocrine resistance in breast cancer

(2011) Katherine L Cook et al.   Expert Review of Anticancer Therapy

Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy

(2011) Chien-Ju Lin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy suppression promotes apoptotic cell death in response to inhibition of the PI3K—mTOR pathway in pancreatic adenocarcinoma

(2011) Olga K. Mirzoeva et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Suppression of Autophagy by FIP200 Deletion Impairs DNA Damage Repair and Increases Cell Death upon Treatments with Anticancer Agents

(2011) H. Bae et al.   MOLECULAR CANCER RESEARCH

HDACs link the DNA damage response, processing of double-strand breaks and autophagy

(2011) Thomas Robert et al.   NATURE

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Inhibition of AMPK-Associated Autophagy Enhances Caffeic Acid Phenethyl Ester-Induced Cell Death in C6 Glioma Cells

(2011) Szu-Hsu Yu et al.   PLANTA MEDICA

Evidence for the interplay between JNK and p53-DRAM signaling pathways in the regulation of autophagy

(2010) Séverine Lorin et al.   Autophagy

ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy

(2010) Liang Qin et al.   Autophagy

Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway

(2010) Li-Hsin Chen et al.   BIOCHEMICAL PHARMACOLOGY

Cytoprotective roles for autophagy

(2010) Kevin Moreau et al.   CURRENT OPINION IN CELL BIOLOGY

Autophagy inhibition contributes to radiation sensitization of esophageal squamous carcinoma cells

(2010) Y. S. Chen et al.   DISEASES OF THE ESOPHAGUS

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Autophagy Induction by Capsaicin in Malignant Human Breast Cells Is Modulated by p38 and Extracellular Signal-Regulated Mitogen-Activated Protein Kinases and Retards Cell Death by Suppressing Endoplasmic Reticulum Stress-Mediated Apoptosis

(2010) C.-H. Choi et al.   MOLECULAR PHARMACOLOGY

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Beclin 1–VPS34 complex – at the crossroads of autophagy and beyond

(2010) Sarah F. Funderburk et al.   TRENDS IN CELL BIOLOGY

The role of autophagy in sensitizing malignant glioma cells to radiation therapy

(2009) W. Zhuang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Targeted therapies and autophagy: new insights from chronic myeloid leukemia

(2009) Paolo Salomoni et al.   Autophagy

The Role of ATF4 Stabilization and Autophagy in Resistance of Breast Cancer Cells Treated with Bortezomib

(2009) M. Milani et al.   CANCER RESEARCH

Engineered therapeutic antibodies with improved effector functions

(2009) Tsuguo Kubota et al.   CANCER SCIENCE

Hypoxia-induced autophagy: cell death or cell survival?

(2009) Nathalie M Mazure et al.   CURRENT OPINION IN CELL BIOLOGY

The induction of autophagy by γ-radiation contributes to the radioresistance of glioma stem cells

(2009) Stephanie L. Lomonaco et al.   INTERNATIONAL JOURNAL OF CANCER

Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes

(2009) Anne Simonsen et al.   JOURNAL OF CELL BIOLOGY

Simian Virus 40 Small T Antigen Activates AMPK and Triggers Autophagy To Protect Cancer Cells from Nutrient Deprivation

(2009) S. H. Kumar et al.   JOURNAL OF VIROLOGY

Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells

(2009) Donglei Liu et al.   MEDICAL ONCOLOGY

Autophagy Facilitates the Development of Breast Cancer Resistance to the Anti-HER2 Monoclonal Antibody Trastuzumab

(2009) Alejandro Vazquez-Martin et al.   PLoS One

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism

(2008) Xin-Hua Liao et al.   AMINO ACIDS

Redox Regulation of Cell Survival

(2008) Dunyaporn Trachootham et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy: A lysosomal degradation pathway with a central role in health and disease

(2008) Eeva-Liisa Eskelinen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization

(2008) M. A. Qadir et al.   BREAST CANCER RESEARCH AND TREATMENT

Blocked Autophagy Sensitizes Resistant Carcinoma Cells to Radiation Therapy

(2008) A. Apel et al.   CANCER RESEARCH

p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling

(2008) Andrei V. Budanov et al.   CELL

Extracellular matrix regulation of autophagy

(2008) Rebecca Lock et al.   CURRENT OPINION IN CELL BIOLOGY

The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Jiefei Geng et al.   EMBO REPORTS

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

p53: The Janus of autophagy?

(2008) Beth Levine et al.   NATURE CELL BIOLOGY

Regulation of autophagy by cytoplasmic p53

(2008) Ezgi Tasdemir et al.   NATURE CELL BIOLOGY