CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

(2013) Jaeseok Han et al.   NATURE CELL BIOLOGY

Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

(2012) Christine M. Oslowski et al.   Cell Metabolism

IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

(2012) Alana G. Lerner et al.   Cell Metabolism

Nucleophosmin (NPM1/B23) Interacts with Activating Transcription Factor 5 (ATF5) Protein and Promotes Proteasome- and Caspase-dependent ATF5 Degradation in Hepatocellular Carcinoma Cells

(2012) Xijun Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Eukaryotic Initiation Factor 2 Phosphorylation and Translational Control in Metabolism

(2012) Thomas D. Baird et al.   Advances in Nutrition

The Transcription Factor Network Associated With the Amino Acid Response in Mammalian Cells

(2012) Michael S. Kilberg et al.   Advances in Nutrition

Phosphorylation of eIF2 Facilitates Ribosomal Bypass of an Inhibitory Upstream ORF to EnhanceCHOPTranslation

(2011) Lakshmi Reddy Palam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress

(2011) Brian F. Teske et al.   MOLECULAR BIOLOGY OF THE CELL

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

A switch from life to death in endoplasmic reticulum stressed β-cells

(2010) C. M. Oslowski et al.   DIABETES OBESITY & METABOLISM

Molecular Symbiosis of CHOP and C/EBP  Isoform LIP Contributes to Endoplasmic Reticulum Stress-Induced Apoptosis

(2010) C.-B. Chiribau et al.   MOLECULAR AND CELLULAR BIOLOGY

Biological and Chemical Approaches to Diseases of Proteostasis Deficiency

(2009) Evan T. Powers et al.   Annual Review of Biochemistry

An Upstream Open Reading Frame Regulates Translation of GADD34 during Cellular Stresses That Induce eIF2α Phosphorylation

(2009) Yun-Young Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Noxa: at the tip of the balance between life and death

(2009) C Ploner et al.   ONCOGENE

ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

(2009) Q. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATF4-dependent transcription mediates signaling of amino acid limitation

(2009) Michael S. Kilberg et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Cdc34-mediated Degradation of ATF5 Is Blocked by Cisplatin

(2008) Yuanyan Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of eIF2 DirectsATF5Translational Control in Response to Diverse Stress Conditions

(2008) Donghui Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The transcription factor ATF5: role in neurodevelopment and neural tumors

(2008) Lloyd A. Greene et al.   JOURNAL OF NEUROCHEMISTRY

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY