TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators

Pathways of Unconventional Protein Secretion

(2017) Catherine Rabouille   TRENDS IN CELL BIOLOGY

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

COMP-assisted collagen secretion – a novel intracellular function required for fibrosis

(2016) Jan-Niklas Schulz et al.   JOURNAL OF CELL SCIENCE

Secretory autophagy

(2015) Marisa Ponpuak et al.   CURRENT OPINION IN CELL BIOLOGY

Interleukin-4 Receptor α Signaling in Myeloid Cells Controls Collagen Fibril Assembly in Skin Repair

(2015) Johanna A. Knipper et al.   IMMUNITY

Reduced Granulation Tissue and Wound Strength in the Absence of α11β1 Integrin

(2015) Jan-Niklas Schulz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The extracellular matrix and transforming growth factor-β1: Tale of a strained relationship

(2015) Boris Hinz   MATRIX BIOLOGY

Proteoglycans regulate autophagy via outside-in signaling: an emerging new concept

(2015) Maria A. Gubbiotti et al.   MATRIX BIOLOGY

Latent TGF-β-binding proteins

(2015) Ian B. Robertson et al.   MATRIX BIOLOGY

The fibrillin microfibril scaffold: A niche for growth factors and mechanosensation?

(2015) Gerhard Sengle et al.   MATRIX BIOLOGY

Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis

(2015) Katrin Palumbo-Zerr et al.   NATURE MEDICINE

Transforming growth factor β—at the centre of systemic sclerosis

(2014) Robert Lafyatis   Nature Reviews Rheumatology

Tension-induced autophagy

(2013) Anna Ulbricht et al.   Autophagy

ILK: a pseudokinase with a unique function in the integrin–actin linkage

(2013) Sushmita Ghatak et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The weakest link: A new paradigm for stabilizing the integrin–actin connection

(2013) Jessica Morgner et al.   CELL CYCLE

Cellular Mechanotransduction Relies on Tension-Induced and Chaperone-Assisted Autophagy

(2013) Anna Ulbricht et al.   CURRENT BIOLOGY

Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response

(2013) Korana Radovanac et al.   EMBO JOURNAL

Tubulin Polymerization-promoting Protein (TPPP/p25α) Promotes Unconventional Secretion of α-Synuclein through Exophagy by Impairing Autophagosome-Lysosome Fusion

(2013) Patrick Ejlerskov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diversity in unconventional protein secretion

(2013) Catherine Rabouille et al.   JOURNAL OF CELL SCIENCE

Alternative fates of newly formed PrPSc upon prion conversion on the plasma membrane

(2013) R. Goold et al.   JOURNAL OF CELL SCIENCE

Secretory versus Degradative Autophagy: Unconventional Secretion of Inflammatory Mediators

(2013) Shanya Jiang et al.   Journal of Innate Immunity

Unconventional Secretion, Unconventional Solutions

(2013) M. Zhang et al.   SCIENCE

The actin cytoskeleton participates in the early events of autophagosome formation upon starvation induced autophagy

(2012) Milton Osmar Aguilera et al.   Autophagy

TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation

(2012) Manohar Pilli et al.   IMMUNITY

Matrix control of transforming growth factor-  function

(2012) M. Horiguchi et al.   JOURNAL OF BIOCHEMISTRY

Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5-bisphosphate and phospholipase D

(2012) Kevin Moreau et al.   JOURNAL OF CELL BIOLOGY

LTBPs, more than just an escort service

(2012) Vesna Todorovic et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Specificity of latent TGF-β binding protein (LTBP) incorporation into matrix: Role of fibrillins and fibronectin

(2012) Lior Zilberberg et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy intersections with conventional and unconventional secretion in tissue development, remodeling and inflammation

(2012) Vojo Deretic et al.   TRENDS IN CELL BIOLOGY

The Single-Molecule Mechanics of the Latent TGF-β1 Complex

(2011) Lara Buscemi et al.   CURRENT BIOLOGY

Unconventional secretion: a stress on GRASP

(2011) Fabrizio Giuliani et al.   CURRENT OPINION IN CELL BIOLOGY

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

(2011) Nicolas Dupont et al.   EMBO JOURNAL

The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading

(2011) Gary J. Doherty et al.   MOLECULAR BIOLOGY OF THE CELL

Latent TGF-β structure and activation

(2011) Minlong Shi et al.   NATURE

Rho protein crosstalk: another social network?

(2011) Christophe Guilluy et al.   TRENDS IN CELL BIOLOGY

Cross Talk among TGF-  Signaling Pathways, Integrins, and the Extracellular Matrix

(2011) J. S. Munger et al.   Cold Spring Harbor Perspectives in Biology

Interleukin-1, inflammasomes and the skin

(2010) Laurence Feldmeyer et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Two Distinct Regions of Latency-associated Peptide Coordinate Stability of the Latent Transforming Growth Factor-β1 Complex

(2010) Kelly L. Walton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unconventional secretion of Acb1 is mediated by autophagosomes

(2010) Juan M. Duran et al.   JOURNAL OF CELL BIOLOGY

Unconventional secretion ofPichia pastorisAcb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation

(2010) Ravi Manjithaya et al.   JOURNAL OF CELL BIOLOGY

Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts - role of TGF 1 levels and RhoA activity

(2010) K. Blumbach et al.   JOURNAL OF CELL SCIENCE

Mutations in Fibrillin-1 Cause Congenital Scleroderma: Stiff Skin Syndrome

(2010) B. L. Loeys et al.   Science Translational Medicine

Genetic Analyses of Integrin Signaling

(2010) S. A. Wickstrom et al.   Cold Spring Harbor Perspectives in Biology

Transforming growth factor beta (TGF-β) and inflammation in cancer

(2009) Brian Bierie et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase!

(2009) Sara A Wickström et al.   EMBO JOURNAL

GRASP65 and GRASP55 Sequentially Promote the Transport of C-terminal Valine-bearing Cargos to and through the Golgi Complex

(2009) Giovanni D'Angelo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Latent Transforming Growth Factor β-binding Proteins and Fibulins Compete for Fibrillin-1 and Exhibit Exquisite Specificities in Binding Sites

(2009) Robert N. Ono et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mice that lack activity of  v 6- and  v 8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice

(2009) P. Aluwihare et al.   JOURNAL OF CELL SCIENCE

Integrin-linked kinase is an adaptor with essential functions during mouse development

(2009) Anika Lange et al.   NATURE

Scleroderma

(2009) Armando Gabrielli et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

MT1-MMP releases latent TGF-β1 from endothelial cell extracellular matrix via proteolytic processing of LTBP-1

(2008) O TATTI et al.   EXPERIMENTAL CELL RESEARCH

A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo

(2008) Z. Z. Lieu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA