COMP-assisted collagen secretion – a novel intracellular function required for fibrosis

Reduced Granulation Tissue and Wound Strength in the Absence of α11β1 Integrin

(2015) Jan-Niklas Schulz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Molecular and cellular basis of scleroderma

(2014) Beate Eckes et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Matrilin-1 Is Essential for Zebrafish Development by Facilitating Collagen II Secretion

(2013) Cristian Dan Neacsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhanced deposition of cartilage oligomeric matrix protein is a common feature in fibrotic skin pathologies

(2013) Pallavi Agarwal et al.   MATRIX BIOLOGY

Using transmission electron microscopy and 3View to determine collagen fibril size and three-dimensional organization

(2013) Tobias Starborg et al.   Nature Protocols

Recent Developments in Myofibroblast Biology

(2012) Boris Hinz et al.   AMERICAN JOURNAL OF PATHOLOGY

A Thrombospondin-Dependent Pathway for a Protective ER Stress Response

(2012) Jeffrey M. Lynch et al.   CELL

Thrombospondin-4 regulates fibrosis and remodeling of the myocardium in response to pressure overload

(2012) Ella G. Frolova et al.   FASEB JOURNAL

CHOP is a multifunctional transcription factor in the ER stress response

(2012) H. Nishitoh   JOURNAL OF BIOCHEMISTRY

Collagen XII and XIV, New Partners of Cartilage Oligomeric Matrix Protein in the Skin Extracellular Matrix Suprastructure

(2012) Pallavi Agarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thrombospondin1 in tissue repair and fibrosis: TGF-β-dependent and independent mechanisms

(2012) Mariya T. Sweetwyne et al.   MATRIX BIOLOGY

Ubiquitin-dependent regulation of COPII coat size and function

(2012) Lingyan Jin et al.   NATURE

Molecular basis for the action of the collagen-specific chaperone Hsp47/SERPINH1 and its structure-specific client recognition

(2012) C. Widmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a 3Kbp Mechanoresponsive Promoter Region in the Human Cartilage Oligomeric Matrix Protein Gene

(2012) Derek F. Amanatullah et al.   TISSUE ENGINEERING PART A

D469del-COMP Retention in Chondrocytes Stimulates Caspase-Independent Necroptosis

(2011) Françoise Coustry et al.   AMERICAN JOURNAL OF PATHOLOGY

Thrombospondin-4 Is Required for Stretch-Mediated Contractility Augmentation in Cardiac Muscle

(2011) Oscar H. Cingolani et al.   CIRCULATION RESEARCH

cTAGE5 mediates collagen secretion through interaction with TANGO1 at endoplasmic reticulum exit sites

(2011) Kota Saito et al.   MOLECULAR BIOLOGY OF THE CELL

The Calreticulin-Binding Sequence of Thrombospondin 1 Regulates Collagen Expression and Organization During Tissue Remodeling

(2010) Mariya T. Sweetwyne et al.   AMERICAN JOURNAL OF PATHOLOGY

A four-gene biomarker predicts skin disease in patients with diffuse cutaneous systemic sclerosis

(2010) G. Farina et al.   ARTHRITIS AND RHEUMATISM

The matrilins: Modulators of extracellular matrix assembly

(2010) Andreas R. Klatt et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts - role of TGF 1 levels and RhoA activity

(2010) K. Blumbach et al.   JOURNAL OF CELL SCIENCE

The role of the cartilage matrix in osteoarthritis

(2010) Dick Heinegård et al.   Nature Reviews Rheumatology

The Collagen Family

(2010) S. Ricard-Blum   Cold Spring Harbor Perspectives in Biology

An Inducible Cartilage Oligomeric Matrix Protein Mouse Model Recapitulates Human Pseudoachondroplasia Phenotype

(2009) Karen L. Posey et al.   AMERICAN JOURNAL OF PATHOLOGY

Suprastructures of extracellular matrices: paradigms of functions controlled by aggregates rather than molecules

(2009) Peter Bruckner   CELL AND TISSUE RESEARCH

A mouse model offers novel insights into the myopathy and tendinopathy often associated with pseudoachondroplasia and multiple epiphyseal dysplasia

(2009) Katarzyna A. Piróg et al.   HUMAN MOLECULAR GENETICS

Fell-Muir Lecture: Proteoglycans and more - from molecules to biology

(2009) Dick Heinegård   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Scleroderma

(2009) Armando Gabrielli et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Cartilage oligomeric matrix protein expression in systemic sclerosis reveals heterogeneity of dermal fibroblast responses to transforming growth factor  

(2008) G Farina et al.   ANNALS OF THE RHEUMATIC DISEASES

The Role of Cartilage Oligomeric Matrix Protein (COMP) in Skeletal Disease

(2008) K. Posey et al.   CURRENT DRUG TARGETS

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE

Transgenic mice expressing D469Δ mutated cartilage oligomeric matrix protein (COMP) show growth plate abnormalities and sternal malformations

(2007) Markus Schmitz et al.   MATRIX BIOLOGY