Oxidative stress in normal hematopoietic stem cells and leukemia

ROS signalling in the biology of cancer

(2018) Jennifer N. Moloney et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway

(2017) Yang Zhao et al.   Molecular Cancer

ROS in Cancer: The Burning Question

(2017) Iok In Christine Chio et al.   TRENDS IN MOLECULAR MEDICINE

Acute myeloid leukemia in the vascular niche

(2016) Christopher R. Cogle et al.   CANCER LETTERS

The bad seed: Cancer stem cells in tumor development and resistance

(2016) Elle Koren et al.   DRUG RESISTANCE UPDATES

Oxidative stress and hypoxia in normal and leukemic stem cells

(2016) Ugo Testa et al.   EXPERIMENTAL HEMATOLOGY

Alteration of classical and hematopoiesis specific p53 pathway in the bone marrow hematopoietic stem/progenitor compartment facilitates leukemia progression in experimental mice

(2016) Ritam Chatterjee et al.   LEUKEMIA RESEARCH

Acquired expression of osteopontin selectively promotes enrichment of leukemia stem cells through AKT/mTOR/PTEN/β-catenin pathways in AML cells

(2016) Saeed Mohammadi et al.   LIFE SCIENCES

Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies

(2016) Vibha Rani et al.   LIFE SCIENCES

Roles of peroxiredoxins in cancer, neurodegenerative diseases and inflammatory diseases

(2016) Mi Hee Park et al.   PHARMACOLOGY & THERAPEUTICS

Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer

(2016) Caroline Wigerup et al.   PHARMACOLOGY & THERAPEUTICS

ROS homeostasis and metabolism: a dangerous liason in cancer cells

(2016) E Panieri et al.   Cell Death & Disease

Cross-talk between two antioxidants, thioredoxin reductase and heme oxygenase-1, and therapeutic implications for multiple myeloma

(2016) Prahlad V. Raninga et al.   Redox Biology

The thioredoxin system in breast cancer cell invasion and migration

(2016) Maneet Bhatia et al.   Redox Biology

Oxidative Stress, Bone Marrow Failure, and Genome Instability in Hematopoietic Stem Cells

(2015) Christine Richardson et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Redox Regulation in Cancer Stem Cells

(2015) Shijie Ding et al.   Oxidative Medicine and Cellular Longevity

The p53 Isoform Δ133p53β Promotes Cancer Stem Cell Potential

(2015) Nikola Arsic et al.   Stem Cell Reports

Hyperoxia activates ATM independent from mitochondrial ROS and dysfunction

(2015) Emily A. Resseguie et al.   Redox Biology

Antioxidant responses and cellular adjustments to oxidative stress

(2015) Cristina Espinosa-Diez et al.   Redox Biology

Dynamic Changes in Intracellular ROS Levels Regulate Airway Basal Stem Cell Homeostasis through Nrf2-Dependent Notch Signaling

(2014) Manash K. Paul et al.   Cell Stem Cell

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Glutaredoxin 1, glutaredoxin 2, thioredoxin 1, and thioredoxin peroxidase 3 play important roles in antioxidant defense in Apis cerana cerana

(2014) Pengbo Yao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Loss of  -catenin triggers oxidative stress and impairs hematopoietic regeneration

(2014) W. Lento et al.   GENES & DEVELOPMENT

Dual effect of oxidative stress on leukemia cancer induction and treatment

(2014) Udensi K Udensi et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Nrf2, a Regulator of the Proteasome, Controls Self-Renewal and Pluripotency in Human Embryonic Stem Cells

(2014) Jiwon Jang et al.   STEM CELLS

Deadly crosstalk: Notch signaling at the intersection of EMT and cancer stem cells

(2013) Ingrid Espinoza et al.   CANCER LETTERS

HIF-2α Protects Human Hematopoietic Stem/Progenitors and Acute Myeloid Leukemic Cells from Apoptosis Induced by Endoplasmic Reticulum Stress

(2013) Kevin Rouault-Pierre et al.   Cell Stem Cell

Bone marrow neoplastic niche in leukemia

(2013) Shirin Azizidoost et al.   Hematology

Novel roles of reactive oxygen species in the pathogenesis of acute myeloid leukemia

(2013) Fuling Zhou et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Altered gene products involved in the malignant reprogramming of cancer stem/progenitor cells and multitargeted therapies

(2013) Murielle Mimeault et al.   MOLECULAR ASPECTS OF MEDICINE

Intracellular Reactive Oxygen Species Mark and Influence the Megakaryocyte-Erythrocyte Progenitor Fate of Common Myeloid Progenitors

(2013) Akihito Shinohara et al.   STEM CELLS

ROS-mediated platelet generation: a microenvironment-dependent manner for megakaryocyte proliferation, differentiation and maturation

(2013) S Chen et al.   Cell Death & Disease

Redox homeostasis: the linchpin in stem cell self-renewal and differentiation

(2013) Kui Wang et al.   Cell Death & Disease

Reactive Oxygen Species in Cancer Stem Cells

(2012) Xiaoke Shi et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Control of Leukemia: From Molecular Mechanisms to Therapeutic Opportunities

(2012) Mary E. Irwin et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of mitochondrial metabolism: yet another facet in the biology of the oncoprotein Bcl-2

(2011) Shefali Krishna et al.   BIOCHEMICAL JOURNAL

Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells

(2011) T. Yahata et al.   BLOOD

Do reactive oxygen species play a role in myeloid leukemias?

(2011) P. S. Hole et al.   BLOOD

Inhibition of the NADPH oxidase regulates heme oxygenase 1 expression in chronic myeloid leukemia

(2011) Melissa M. Singh et al.   CANCER

Reactive oxygen species: Are they important for haematopoiesis?

(2011) José L. Sardina et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Tumor suppressor genes and ROS: complex networks of interactions

(2011) Beyza Vurusaner et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of reactive oxygen species in stem cells and cancer stem cells

(2011) Chiharu I. Kobayashi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Evolution of human BCR–ABL1 lymphoblastic leukaemia-initiating cells

(2011) Faiyaz Notta et al.   NATURE

Wnt/β-catenin Signaling in Normal and Cancer Stem Cells

(2011) Kenneth C. Valkenburg et al.   Cancers

Cancer Chemoprevention Mechanisms Mediated Through the Keap1–Nrf2 Pathway

(2010) John D. Hayes et al.   ANTIOXIDANTS & REDOX SIGNALING

AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species

(2010) M. M. Juntilla et al.   BLOOD

The Canonical NF- B Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion

(2010) M. Liu et al.   CANCER RESEARCH

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Hypoxia Signaling in Hematopoietic Stem Cells: A Double-Edged Sword

(2010) Patrick J. Pollard et al.   Cell Stem Cell

The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche

(2010) Tugba Simsek et al.   Cell Stem Cell

Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells

(2010) Keiyo Takubo et al.   Cell Stem Cell

ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair

(2010) Claudia Cosentino et al.   EMBO JOURNAL

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases

(2010) M M Reddy et al.   LEUKEMIA

Thioredoxin and Cancer: A Role for Thioredoxin in all States of Tumor Oxygenation

(2010) Therese Christina Karlenius et al.   Cancers

Role of Oxidative Stress in Stem, Cancer, and Cancer Stem Cells

(2010) Ahmed Abdal Dayem et al.   Cancers

Balancing dormant and self-renewing hematopoietic stem cells

(2009) Anne Wilson et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Oxidative Stress Promotes Transcriptional Up-regulation of Fyn in BCR-ABL1-expressing Cells

(2009) Yin Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The hematopoietic stem cell niche: Low in oxygen but a nice place to be

(2009) Pernilla Eliasson et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Overexpression of peroxiredoxin I and thioredoxin1 in human breast carcinoma

(2009) Mee-Kyung Cha et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Oxidative Stress and Oxidative Damage in Carcinogenesis

(2009) James E. Klaunig et al.   TOXICOLOGIC PATHOLOGY

Regulation of Reactive Oxygen Species and Genomic Stability in Hematopoietic Stem Cells

(2008) Kazuhito Naka et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Regulation of Cell Survival

(2008) Dunyaporn Trachootham et al.   ANTIOXIDANTS & REDOX SIGNALING

BCR-ABL1 mediates up-regulation of Fyn in chronic myelogenous leukemia

(2008) K. Ban et al.   BLOOD

Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: implications for poor prognosis in AML

(2008) A. Sallmyr et al.   BLOOD

The PI-3kinase pathway in hematopoietic stem cells and leukemia-initiating cells: A mechanistic difference between normal and cancer stem cells

(2008) Ömer H. Yilmaz et al.   BLOOD CELLS MOLECULES AND DISEASES

Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy

(2008) Masuko Ushio-Fukai et al.   CANCER LETTERS

Elevated copper and oxidative stress in cancer cells as a target for cancer treatment

(2008) Anshul Gupte et al.   CANCER TREATMENT REVIEWS

TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

(2008) Chong Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bcl-2 family proteins as regulators of oxidative stress

(2008) Nathan Susnow et al.   SEMINARS IN CANCER BIOLOGY