Detecting cell-secreted growth factors in microfluidic devices using bead-based biosensors

Microfluidic compartments with sensing microbeads for dynamic monitoring of cytokine and exosome release from single cells

(2016) Kyung Jin Son et al.   ANALYST

PEG-fibrinogen hydrogels for three-dimensional breast cancer cell culture

(2016) Shantanu Pradhan et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Embryonic Stem Cells Cultured in Microfluidic Chambers Take Control of Their Fate by Producing Endogenous Signals Including LIF

(2016) Joshua Guild et al.   STEM CELLS

High-Content Quantification of Single-Cell Immune Dynamics

(2016) Michael Junkin et al.   Cell Reports

Cell biology is different in small volumes: endogenous signals shape phenotype of primary hepatocytes cultured in microfluidic channels

(2016) Amranul Haque et al.   Scientific Reports

Biosensors for Cell Analysis

(2015) Qing Zhou et al.   Annual Review of Biomedical Engineering

Approaching near real-time biosensing: Microfluidic microsphere based biosensor for real-time analyte detection

(2015) Noa Cohen et al.   BIOSENSORS & BIOELECTRONICS

Using reconfigurable microfluidics to study the role of HGF in autocrine and paracrine signaling of hepatocytes

(2015) Dipali Patel et al.   Integrative Biology

Microfluidic co-cultures with hydrogel-based ligand trap to study paracrine signals giving rise to cancer drug resistance

(2015) Dipali Patel et al.   LAB ON A CHIP

Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands

(2015) Yao Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The present and future role of microfluidics in biomedical research

(2014) Eric K. Sackmann et al.   NATURE

Single-cell technologies for monitoring immune systems

(2014) Pratip K Chattopadhyay et al.   NATURE IMMUNOLOGY

Local control of hepatic phenotype with growth factor-encoded surfaces

(2013) Dipali Patel et al.   Integrative Biology

On-chip regeneration of aptasensors for monitoring cell secretion

(2013) Qing Zhou et al.   LAB ON A CHIP

Single-cell analysis and sorting using droplet-based microfluidics

(2013) Linas Mazutis et al.   Nature Protocols

Multiplexed Detection of mRNA Using Porosity-Tuned Hydrogel Microparticles

(2012) Nak Won Choi et al.   ANALYTICAL CHEMISTRY

Probing Embryonic Stem Cell Autocrine and Paracrine Signaling Using Microfluidics

(2012) Laralynne Przybyla et al.   Annual Review of Analytical Chemistry

Attenuation of extrinsic signaling reveals the importance of matrix remodeling on maintenance of embryonic stem cell self-renewal

(2012) L. M. Przybyla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Micropatterned Aptasensors for Continuous Monitoring of Cytokine Release from Human Leukocytes

(2011) Ying Liu et al.   ANALYTICAL CHEMISTRY

A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells

(2011) Chao Ma et al.   NATURE MEDICINE

Physical limits of cells and proteomes

(2011) K. A. Dill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polyfunctional responses by human T cells result from sequential release of cytokines

(2011) Q. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of Macroporous Poly(ethylene glycol) Hydrogel Arrays within Microfluidic Channels

(2010) Andrew G. Lee et al.   BIOMACROMOLECULES

Controlling the Porosity and Microarchitecture of Hydrogels for Tissue Engineering

(2010) Nasim Annabi et al.   TISSUE ENGINEERING PART B-REVIEWS

From the cellular perspective: exploring differences in the cellular baseline in macroscale and microfluidic cultures

(2009) Amy L. Paguirigan et al.   Integrative Biology

Partitioning microfluidic channels with hydrogel to construct tunable 3-D cellular microenvironments

(2008) Amy P. Wong et al.   BIOMATERIALS

Concurrent detection of secreted products from human lymphocytes by microengraving: Cytokines and antigen-reactive antibodies

(2008) Elizabeth M. Bradshaw et al.   CLINICAL IMMUNOLOGY

A microdevice for multiplexed detection of T-cell-secreted cytokines

(2008) He Zhu et al.   LAB ON A CHIP