Design of biomimetic cellular scaffolds for co-culture system and their application

Unraveling cell-to-cell signaling networks with chemical biology

(2017) Zev J Gartner et al.   Nature Chemical Biology

A transgenic rat hepatocyte - Kupffer cell co-culture model for evaluation of direct and macrophage-related effect of poly(amidoamine) dendrimers

(2017) Katalin Jemnitz et al.   TOXICOLOGY IN VITRO

Electrospinning design of functional nanostructures for biosensor applications

(2017) Mingfa Zhang et al.   Journal of Materials Chemistry B

Cartilage Tissue Engineering by the 3D Bioprinting of iPS Cells in a Nanocellulose/Alginate Bioink

(2017) Duong Nguyen et al.   Scientific Reports

Novel Platform of Cardiomyocyte Culture and Coculture via Fibroblast-Derived Matrix-Coupled Aligned Electrospun Nanofiber

(2016) Muhammad Suhaeri et al.   ACS Applied Materials & Interfaces

A human macrophage – hepatocyte co-culture model for comparative studies of infection and replication of Francisella tularensis LVS strain and subspecies holarctica and mediasiatica

(2016) Knut Rennert et al.   BMC MICROBIOLOGY

Bi-compartmental 3D scaffolds for the co-culture of intervertebral disk cells and mesenchymal stem cells

(2016) Yun-Min Kook et al.   JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY

Micropatterned coculture of hepatocytes on electrospun fibers as a potential in vitro model for predictive drug metabolism

(2016) Yaowen Liu et al.   Materials Science & Engineering C-Materials for Biological Applications

Angiocrine functions of organ-specific endothelial cells

(2016) Shahin Rafii et al.   NATURE

Deterministic encapsulation of single cells in thin tunable microgels for niche modelling and therapeutic delivery

(2016) Angelo S. Mao et al.   NATURE MATERIALS

A practical guide to hydrogels for cell culture

(2016) Steven R Caliari et al.   NATURE METHODS

Tight junctions: from simple barriers to multifunctional molecular gates

(2016) Ceniz Zihni et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Spatiotemporal control of cell–cell reversible interactions using molecular engineering

(2016) Peng Shi et al.   Nature Communications

Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor Microenvironment

(2016) Su-Yeong Jeong et al.   PLoS One

Establishment of 3D Co-Culture Models from Different Stages of Human Tongue Tumorigenesis: Utility in Understanding Neoplastic Progression

(2016) Sharada Sawant et al.   PLoS One

Human iPSC-derived osteoblasts and osteoclasts together promote bone regeneration in 3D biomaterials

(2016) Ok Hee Jeon et al.   Scientific Reports

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

(2016) Catherine C. Bell et al.   Scientific Reports

Microfluidic co-culture system for cancer migratory analysis and anti-metastatic drugs screening

(2016) Shengli Mi et al.   Scientific Reports

Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices

(2015) Skarphedinn Halldorsson et al.   BIOSENSORS & BIOELECTRONICS

Role of gap junction communication in hepatocyte/fibroblast co-cultures: Implications for hepatic tissue engineering

(2015) Dongjoo Kim et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Hallmarks of pluripotency

(2015) Alejandro De Los Angeles et al.   NATURE

Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens

(2015) Sandra March et al.   Nature Protocols

Microfluidics: reframing biological enquiry

(2015) Todd A. Duncombe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Long-Term Coculture Strategies for Primary Hepatocytes and Liver Sinusoidal Endothelial Cells

(2015) Shyam Sundhar Bale et al.   TISSUE ENGINEERING PART C-METHODS

Two-dimensional single-cell patterning with one cell per well driven by surface acoustic waves

(2015) David J. Collins et al.   Nature Communications

Static stretch affects neural stem cell differentiation in an extracellular matrix-dependent manner

(2015) Janahan Arulmoli et al.   Scientific Reports

Mesenchymal stem cell-laden anti-inflammatory hydrogel enhances diabetic wound healing

(2015) Shixuan Chen et al.   Scientific Reports

Recent Advances in Applications of Droplet Microfluidics

(2015) Wei-Lung Chou et al.   Micromachines

Microfluidics for cell-cell interactions: A review

(2015) Rui Li et al.   Frontiers of Chemical Science and Engineering

A Triple Culture Model of the Blood-Brain Barrier Using Porcine Brain Endothelial cells, Astrocytes and Pericytes

(2015) Louiza Bohn Thomsen et al.   PLoS One

Hepatocyte Cocultures with Endothelial Cells and Fibroblasts on Micropatterned Fibrous Mats to Promote Liver-Specific Functions and Capillary Formation Capabilities

(2014) Yaowen Liu et al.   BIOMACROMOLECULES

Biomaterials in co-culture systems: Towards optimizing tissue integration and cell signaling within scaffolds

(2014) Kyle G. Battiston et al.   BIOMATERIALS

Advances in 3D cell culture technologies enabling tissue-like structures to be createdin vitro

(2014) Eleanor Knight et al.   JOURNAL OF ANATOMY

Electrospinning of polymeric nanofibers for drug delivery applications

(2014) Xiuli Hu et al.   JOURNAL OF CONTROLLED RELEASE

Sporozoite-Mediated Hepatocyte Wounding Limits Plasmodium Parasite Development via MyD88-Mediated NF- B Activation and Inducible NO Synthase Expression

(2014) R. Torgler et al.   JOURNAL OF IMMUNOLOGY

Co-culture systems and technologies: taking synthetic biology to the next level

(2014) L. Goers et al.   Journal of the Royal Society Interface

Potency unchained

(2014) Austin Smith   NATURE

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications

(2014) Ying Wang et al.   NATURE IMMUNOLOGY

Extracellular matrix assembly: a multiscale deconstruction

(2014) Janna K. Mouw et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Origin and function of cartilage stem/progenitor cells in osteoarthritis

(2014) Yangzi Jiang et al.   Nature Reviews Rheumatology

Repair and tissue engineering techniques for articular cartilage

(2014) Eleftherios A. Makris et al.   Nature Reviews Rheumatology

Design of biocompatible and biodegradable polymers based on intermediate water concept

(2014) Masaru Tanaka et al.   POLYMER JOURNAL

A novel electrospun biphasic scaffold provides optimal three-dimensional topography forin vitroco-culture of airway epithelial and fibroblast cells

(2014) G E Morris et al.   Biofabrication

A three-dimensional co-culture of HepG2 spheroids and fibroblasts using double-layered fibrous scaffolds incorporated with hydrogel micropatterns

(2014) Hyue Won Lee et al.   RSC Advances

Glycosaminoglycan-based hydrogels to modulate heterocellular communication in in vitro angiogenesis models

(2014) Karolina Chwalek et al.   Scientific Reports

Real-time single-cell imaging of protein secretion

(2014) Yoshitaka Shirasaki et al.   Scientific Reports

Homotypic NK cell-to-cell communication controls cytokine responsiveness of innate immune NK cells

(2014) Tae-Jin Kim et al.   Scientific Reports

Bioactive silicate materials stimulate angiogenesis in fibroblast and endothelial cell co-culture system through paracrine effect

(2013) H. Li et al.   Acta Biomaterialia

Direct and indirect co-culture of chondrocytes and mesenchymal stem cells for the generation of polymer/extracellular matrix hybrid constructs

(2013) Erica J. Levorson et al.   Acta Biomaterialia

Seeding Cells on Calcium Phosphate Scaffolds Using Hydrogel Enhanced Osteoblast Proliferation and Differentiation

(2013) Min-Ho Hong et al.   ANNALS OF BIOMEDICAL ENGINEERING

Co-culture of vascular endothelial cells and smooth muscle cells by hyaluronic acid micro-pattern on titanium surface

(2013) Jingan Li et al.   APPLIED SURFACE SCIENCE

Synergistic effects of nanotopography and co-culture with endothelial cells on osteogenesis of mesenchymal stem cells

(2013) Jangho Kim et al.   BIOMATERIALS

Microfluidic devices for cell cultivation and proliferation

(2013) Masoomeh Tehranirokh et al.   Biomicrofluidics

Techniques for fabrication and construction of three-dimensional scaffolds for tissue engineering

(2013) Tingli Lu et al.   International Journal of Nanomedicine

Biomimetic electrospun nanofibrous structures for tissue engineering

(2013) Xianfeng Wang et al.   Materials Today

Light-guiding hydrogels for cell-based sensing and optogenetic synthesis in vivo

(2013) Myunghwan Choi et al.   Nature Photonics

In Vitro Model of Tumor Cell Extravasation

(2013) Jessie S. Jeon et al.   PLoS One

Crosstalk between Immune Cells and Adipocytes Requires Both Paracrine Factors and Cell Contact to Modify Cytokine Secretion

(2013) Carolina Franco Nitta et al.   PLoS One

How Cells Know Where They Are

(2013) A. D. Lander   SCIENCE

In vitro fabrication of functional three-dimensional tissues with perfusable blood vessels

(2013) Hidekazu Sekine et al.   Nature Communications

Stem cells catalyze cartilage formation by neonatal articular chondrocytes in 3D biomimetic hydrogels

(2013) Janice H. Lai et al.   Scientific Reports

Engineering osteochondral constructs through spatial regulation of endochondral ossification

(2012) Eamon J. Sheehy et al.   Acta Biomaterialia

Osteogenic and angiogenic potentials of monocultured and co-cultured human-bone-marrow-derived mesenchymal stem cells and human-umbilical-vein endothelial cells on three-dimensional porous beta-tricalcium phosphate scaffold

(2012) Yunqing Kang et al.   Acta Biomaterialia

Functional Human Vascular Network Generated in Photocrosslinkable Gelatin Methacrylate Hydrogels

(2012) Ying-Chieh Chen et al.   ADVANCED FUNCTIONAL MATERIALS

Complex heterogeneous tissue constructs containing multiple cell types prepared by inkjet printing technology

(2012) Tao Xu et al.   BIOMATERIALS

Endothelial invasive response in a co-culture model with physically-induced osteodifferentiation

(2012) Samantha B Traphagen et al.   Journal of Tissue Engineering and Regenerative Medicine

Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels

(2012) Yoojin Shin et al.   Nature Protocols

High-throughput combinatorial cell co-culture using microfluidics

(2011) Ethan Tumarkin et al.   Integrative Biology

Microfluidic chemostat and turbidostat with flow rate, oxygen, and temperature control for dynamic continuous culture

(2011) Kevin S. Lee et al.   LAB ON A CHIP

The elusive nature and function of mesenchymal stem cells

(2011) César Nombela-Arrieta et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structured Bilaminar Coculture Outperforms Stem Cells and Disc Cells in a Simulated Degenerate Disc Environment

(2011) Aliza A. Allon et al.   SPINE

Alginate based 3D hydrogels as an in vitro co-culture model platform for the toxicity screening of new chemical entities

(2011) Shih-Feng Lan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Permeability of Endothelial and Astrocyte Cocultures: In Vitro Blood–Brain Barrier Models for Drug Delivery Studies

(2010) Guanglei Li et al.   ANNALS OF BIOMEDICAL ENGINEERING

Treatment of articular cartilage lesions of the knee

(2010) Mazen Falah et al.   INTERNATIONAL ORTHOPAEDICS

Dendrimer porphyrin-terminated polyelectrolyte multilayer micropatterns for a protein microarray with enhanced sensitivity

(2010) Kyung Jin Son et al.   JOURNAL OF MATERIALS CHEMISTRY

Rapid vascularization of starch-poly(caprolactone) in vivo by outgrowth endothelial cells in co-culture with primary osteoblasts

(2010) Shahram Ghanaati et al.   Journal of Tissue Engineering and Regenerative Medicine

Spatial organization and signal transduction at intercellular junctions

(2010) Boryana N. Manz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Adherens junctions: from molecules to morphogenesis

(2010) Tony J. C. Harris et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Co-culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype

(2010) Sandra Strassburg et al.   Regenerative Medicine

Structured coculture of stem cells and disc cells prevent disc degeneration in a rat model

(2010) Aliza A. Allon et al.   Spine Journal

The effect of the co-immobilization of human osteoprogenitors and endothelial cells within alginate microspheres on mineralization in a bone defect

(2009) Maritie Grellier et al.   BIOMATERIALS

Dynamic culture conditions to generate silk-based tissue-engineered vascular grafts

(2009) Xiaohui Zhang et al.   BIOMATERIALS

Crosstalk between osteoblasts and endothelial cells co-cultured on a polycaprolactone–starch scaffold and the in vitro development of vascularization

(2009) Marina I. Santos et al.   BIOMATERIALS

Cell–cell interaction networks regulate blood stem and progenitor cell fate

(2009) Daniel C Kirouac et al.   Molecular Systems Biology

Chondrogenesis of Adipose-Derived Adult Stem Cells in a Poly-Lactide-Co-Glycolide Scaffold

(2009) Alexander T. Mehlhorn et al.   TISSUE ENGINEERING PART A

Human Adipose-Derived Stem Cells Contribute to Chondrogenesis in Coculture with Human Articular Chondrocytes

(2009) Florian Hildner et al.   TISSUE ENGINEERING PART A

Droplet-Based Microfluidic Platforms for the Encapsulation and Screening of Mammalian Cells and Multicellular Organisms

(2008) Jenifer Clausell-Tormos et al.   CHEMISTRY & BIOLOGY

Brain Endothelial Cell-Cell Junctions: How to “Open” the Blood Brain Barrier

(2008) Svetlana Stamatovic et al.   Current Neuropharmacology

Effect of electrospinning parameters on the nanofiber diameter and length

(2008) Vince Beachley et al.   Materials Science & Engineering C-Materials for Biological Applications

Patterning surfaces with functional polymers

(2008) Zhihong Nie et al.   NATURE MATERIALS

A Review: Electrospinning of Biopolymer Nanofibers and their Applications

(2008) Jessica D. Schiffman et al.   Polymer Reviews

Desmosome structure, composition and function

(2007) David Garrod et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Smooth muscle cell phenotype alters cocultured endothelial cell response to biomaterial-pretreated leukocytes

(2007) Stacey L. Rose et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A