Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor Microenvironment

CD26 a cancer stem cell marker and therapeutic target

(2015) Samuel Davies et al.   BIOMEDICINE & PHARMACOTHERAPY

Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices

(2015) Skarphedinn Halldorsson et al.   BIOSENSORS & BIOELECTRONICS

Fibronectin promotes cell proliferation and invasion through mTOR signaling pathway activation in gallbladder cancer

(2015) Yang Cao et al.   CANCER LETTERS

Microfluidic 3D cell culture: from tools to tissue models

(2015) Vincent van Duinen et al.   CURRENT OPINION IN BIOTECHNOLOGY

Co-culture of 3D tumor spheroids with fibroblasts as a model for epithelial–mesenchymal transition in vitro

(2015) Sun-Ah Kim et al.   EXPERIMENTAL CELL RESEARCH

Improving drug delivery to solid tumors: Priming the tumor microenvironment

(2015) Iftikhar Ali Khawar et al.   JOURNAL OF CONTROLLED RELEASE

Simple surface engineering of polydimethylsiloxane with polydopamine for stabilized mesenchymal stem cell adhesion and multipotency

(2015) Yon Jin Chuah et al.   Scientific Reports

Cancer-associated fibroblasts induce high mobility group box 1 and contribute to resistance to doxorubicin in breast cancer cells

(2015) Kamolporn Amornsupak et al.   BMC CANCER

Dipeptidyl-Peptidase IV Activity Is Correlated with Colorectal Cancer Prognosis

(2015) Gorka Larrinaga et al.   PLoS One

Fibroblasts Influence Survival and Therapeutic Response in a 3D Co-Culture Model

(2015) Meher Majety et al.   PLoS One

Modeling human carcinomas: Physiologically relevant 3D models to improve anti-cancer drug development

(2014) Christine Unger et al.   ADVANCED DRUG DELIVERY REVIEWS

Optimal 3D Culture of Primary Articular Chondrocytes for Use in the Rotating Wall Vessel Bioreactor

(2014) Liliana F. Mellor et al.   AVIATION SPACE AND ENVIRONMENTAL MEDICINE

A microfluidic 3D in vitro model for specificity of breast cancer metastasis to bone

(2014) Simone Bersini et al.   BIOMATERIALS

A microfluidic platform for quantitative analysis of cancer angiogenesis and intravasation

(2014) Hyunjae Lee et al.   Biomicrofluidics

Microfluidic System Based High Throughput Drug Screening System for Curcumin/TRAIL Combinational Chemotherapy in Human Prostate Cancer PC3 Cells

(2014) Dami An et al.   Biomolecules & Therapeutics

GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer

(2014) C. A. Nebiker et al.   CLINICAL CANCER RESEARCH

Hepatic 3D cultures but not 2D cultures preserve specific transporter activity for acetaminophen-induced hepatotoxicity

(2013) L. Schyschka et al.   ARCHIVES OF TOXICOLOGY

Fibroblast-mediated drug resistance in cancer

(2013) Kim H.T. Paraiso et al.   BIOCHEMICAL PHARMACOLOGY

Functional Heterogeneity of Cancer-Associated Fibroblasts from Human Colon Tumors Shows Specific Prognostic Gene Expression Signature

(2013) M. Herrera et al.   CLINICAL CANCER RESEARCH

GDNF increases cell motility in human colon cancer through VEGF–VEGFR1 interaction

(2013) Ssu-Ming Huang et al.   ENDOCRINE-RELATED CANCER

Engineering of functional, perfusable 3D microvascular networks on a chip

(2013) Sudong Kim et al.   LAB ON A CHIP

Evaluation of interstitial protein delivery in multicellular layers model

(2012) Soo-Yeon Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

Advances in the formation, use and understanding of multi-cellular spheroids

(2012) Toni-Marie Achilli et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

(2012) Amir R. Aref et al.   Integrative Biology

Three-dimensional extracellular matrix-mediated neural stem cell differentiation in a microfluidic device

(2012) Sewoon Han et al.   LAB ON A CHIP

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

(2012) Ravid Straussman et al.   NATURE

Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors

(2012) Timothy R. Wilson et al.   NATURE

Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels

(2012) Yoojin Shin et al.   Nature Protocols

Plastic pillar inserts for three-dimensional (3D) cell cultures in 96-well plates

(2012) Dong Woo Lee et al.   SENSORS AND ACTUATORS B-CHEMICAL

A microfluidic system for investigation of extravascular transport and cellular uptake of drugs in tumors

(2011) Nelita T. Elliott et al.   BIOTECHNOLOGY AND BIOENGINEERING

ARNTL2 and SERPINE1: potential biomarkers for tumor aggressiveness in colorectal cancer

(2011) Gianluigi Mazzoccoli et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Mussel-Inspired Polydopamine Coating as a Universal Route to Hydroxyapatite Crystallization

(2010) Jungki Ryu et al.   ADVANCED FUNCTIONAL MATERIALS

Development of a highly metastatic model that reveals a crucial role of fibronectin in lung cancer cell migration and invasion

(2010) Deshui Jia et al.   BMC CANCER

Expression of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinases 1 (TIMP-1) by colorectal cancer cells and adjacent stroma cells – Associations with histopathology and patients outcome

(2010) Søren Astrup Jensen et al.   EUROPEAN JOURNAL OF CANCER

Carcinoma-associated fibroblasts promoted tumor spheroid invasion on a microfluidic 3D co-culture device

(2010) Tingjiao Liu et al.   LAB ON A CHIP

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

(2010) Louis Vermeulen et al.   NATURE CELL BIOLOGY

Tumor-stromal interactions with direct cell contacts enhance proliferation of human pancreatic carcinoma cells

(2009) Hayato Fujita et al.   CANCER SCIENCE

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

The role of CD26/dipeptidyl peptidase IV in cancer

(2007) Pamela et al.   Frontiers in Bioscience-Landmark