Microfluidic devices for cell cultivation and proliferation

Pumpless steady-flow microfluidic chip for cell culture

(2013) Mohana Marimuthu et al.   ANALYTICAL BIOCHEMISTRY

The use of agarose microwells for scalable embryoid body formation and cardiac differentiation of human and murine pluripotent stem cells

(2013) Julia Dahlmann et al.   BIOMATERIALS

Microfluidic construction of minimalistic neuronal co-cultures

(2013) Ngoc-Duy Dinh et al.   LAB ON A CHIP

Culture of primary rat hippocampal neurons: design, analysis, and optimization of a microfluidic device for cell seeding, coherent growth, and solute delivery

(2012) Alexander C. Barbati et al.   BIOMEDICAL MICRODEVICES

Long-term three-dimensional cell culture and anticancer drug activity evaluation in a microfluidic chip

(2012) Karina Ziółkowska et al.   BIOSENSORS & BIOELECTRONICS

An integrated microfluidic cell culture system for high-throughput perfusion three-dimensional cell culture-based assays: effect of cell culture model on the results of chemosensitivity assays

(2012) Song-Bin Huang et al.   LAB ON A CHIP

Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels

(2012) Yoojin Shin et al.   Nature Protocols

Platelet-Derived Growth Factors-BB and Fibroblast Growth Factors-Base Induced Proliferation of Schwann Cells in a 3D Environment

(2012) Huajun Jiang et al.   NEUROCHEMICAL RESEARCH

Recent developments in microfluidic devices for in vitro cell culture for cell-biology research

(2012) Dan Gao et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Dynamic Analysis of Drug-Induced Cytotoxicity Using Chip-Based Dielectrophoretic Cell Immobilization Technology

(2011) Khashayar Khoshmanesh et al.   ANALYTICAL CHEMISTRY

A versatile valve-enabled microfluidic cell co-culture platform and demonstration of its applications to neurobiology and cancer biology

(2011) Yandong Gao et al.   BIOMEDICAL MICRODEVICES

Microfluidic array for three-dimensional perfusion culture of human mammary epithelial cells

(2011) Shin-Yi Cindy Chen et al.   BIOMEDICAL MICRODEVICES

Microfluidic cell culture chip with multiplexed medium delivery and efficient cell/scaffold loading mechanisms for high-throughput perfusion 3-dimensional cell culture-based assays

(2011) Song-Bin Huang et al.   BIOMEDICAL MICRODEVICES

“Artificial micro organs”—a microfluidic device for dielectrophoretic assembly of liver sinusoids

(2011) Julia Schütte et al.   BIOMEDICAL MICRODEVICES

Microfluidics-based devices: New tools for studying cancer and cancer stem cell migration

(2011) Yu Huang et al.   Biomicrofluidics

A modular cell culture device for generating arrays of gradients using stacked microfluidic flows

(2011) Christopher G. Sip et al.   Biomicrofluidics

Stem cells in microfluidics

(2011) Huei-Wen Wu et al.   Biomicrofluidics

Microfluidic devices for studying heterotypic cell-cell interactions and tissue specimen cultures under controlled microenvironments

(2011) Ioannis K. Zervantonakis et al.   Biomicrofluidics

Cellular dielectrophoresis: Applications to the characterization, manipulation, separation and patterning of cells

(2011) Zachary R. Gagnon   ELECTROPHORESIS

3-Dimensional cell culture for on-chip differentiation of stem cells in embryoid body

(2011) Choong Kim et al.   LAB ON A CHIP

Microfluidic chemostat and turbidostat with flow rate, oxygen, and temperature control for dynamic continuous culture

(2011) Kevin S. Lee et al.   LAB ON A CHIP

In vitro 3D collective sprouting angiogenesis under orchestrated ANG-1 and VEGF gradients

(2011) Yoojin Shin et al.   LAB ON A CHIP

Engineering of a microfluidic cell culture platform embedded with nanoscale features

(2011) Yong Yang et al.   LAB ON A CHIP

A software-programmable microfluidic device for automated biology

(2011) Luis M. Fidalgo et al.   LAB ON A CHIP

An integrated microfluidic device for two-dimensional combinatorial dilution

(2011) Yun-Ho Jang et al.   LAB ON A CHIP

A radial microfluidic concentration gradient generator with high-density channels for cell apoptosis assay

(2011) Chun-Guang Yang et al.   LAB ON A CHIP

Ensembles of engineered cardiac tissues for physiological and pharmacological study: Heart on a chip

(2011) Anna Grosberg et al.   LAB ON A CHIP

Quantitatively controlled in situ formation of hydrogel membranes in microchannels for generation of stable chemical gradients

(2011) Eunpyo Choi et al.   LAB ON A CHIP

A digital microfluidic platform for primary cell culture and analysis

(2011) Suthan Srigunapalan et al.   LAB ON A CHIP

Virtual microwells for digital microfluidic reagent dispensing and cell culture

(2011) Irwin A. Eydelnant et al.   LAB ON A CHIP

A digital microfluidic method for multiplexed cell-based apoptosis assays

(2011) Dario Bogojevic et al.   LAB ON A CHIP

Investigation of cell culture in microfluidic devices with different bi-layer substrates

(2011) Jian Shi et al.   MICROELECTRONIC ENGINEERING

Microfluidic bioreactors for culture of non-adherent cells

(2011) Pranjul Shah et al.   SENSORS AND ACTUATORS B-CHEMICAL

Evaluation of cytotoxic effect of 5-fluorouracil on human carcinoma cells in microfluidic system

(2011) E. Jedrych et al.   SENSORS AND ACTUATORS B-CHEMICAL

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

Diffusion-Based and Long-Range Concentration Gradients of Multiple Chemicals for Bacterial Chemotaxis Assays

(2010) Minseok Kim et al.   ANALYTICAL CHEMISTRY

Behavior of HepG2/C3A cell cultures in a microfluidic bioreactor

(2010) Régis Baudoin et al.   BIOCHEMICAL ENGINEERING JOURNAL

Micropatterning neural cell cultures in 3D with a multi-layered scaffold

(2010) Anja Kunze et al.   BIOMATERIALS

Controlled microscale diffusion gradients in quiescent extracellular fluid

(2010) Darren Cherng-Wen Tan et al.   BIOMEDICAL MICRODEVICES

A microfluidic traps system supporting prolonged culture of human embryonic stem cells aggregates

(2010) Maria Khoury et al.   BIOMEDICAL MICRODEVICES

A 3-D microfluidic combinatorial cell array

(2010) Mike C. Liu et al.   BIOMEDICAL MICRODEVICES

A prototypic microfluidic platform generating stepwise concentration gradients for real-time study of cell apoptosis

(2010) Wen Dai et al.   Biomicrofluidics

Dielectrophoretic platforms for bio-microfluidic systems

(2010) Khashayar Khoshmanesh et al.   BIOSENSORS & BIOELECTRONICS

High-throughput methods to define complex stem cell niches

(2010) Stefan Kobel et al.   BIOTECHNIQUES

Compartmental culture of embryonic stem cell-derived neurons in microfluidic devices for use in axonal biology

(2010) Hwa Sung Shin et al.   BIOTECHNOLOGY LETTERS

Fundamentals of microfluidic cell culture in controlled microenvironments

(2010) Edmond W. K. Young et al.   CHEMICAL SOCIETY REVIEWS

Micro-scale and microfluidic devices for neurobiology

(2010) Anne M Taylor et al.   CURRENT OPINION IN NEUROBIOLOGY

Microfluidic gradient platforms for controlling cellular behavior

(2010) Bong Geun Chung et al.   ELECTROPHORESIS

A neuron-benign microfluidic gradient generator for studying the response of mammalian neurons towards axon guidance factors

(2010) Nirveek Bhattacharjee et al.   Integrative Biology

Biological applications of microfluidic gradient devices

(2010) Sudong Kim et al.   Integrative Biology

Progress toward the clinical application of patient-specific pluripotent stem cells

(2010) Evangelos Kiskinis et al.   JOURNAL OF CLINICAL INVESTIGATION

Extensive adipogenic and osteogenic differentiation of patterned human mesenchymal stem cells in a microfluidic device

(2010) Ellen Tenstad et al.   LAB ON A CHIP

Selective arraying of complex particle patterns

(2010) Ramsey I. Zeitoun et al.   LAB ON A CHIP

Microfluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of β-catenin signaling

(2010) Elisa Cimetta et al.   LAB ON A CHIP

An integrated microfluidic system for studying cell-microenvironmental interactions versatilely and dynamically

(2010) Wenming Liu et al.   LAB ON A CHIP

Lab-on-a-chip devices as an emerging platform for stem cell biology

(2010) Kshitiz Gupta et al.   LAB ON A CHIP

A microfluidic platform for probing small artery structure and function

(2010) Axel Günther et al.   LAB ON A CHIP

Perfusion-based microfluidic device for three-dimensional dynamic primary human hepatocyte cell culture in the absence of biological or synthetic matrices or coagulants

(2010) Vasiliy N. Goral et al.   LAB ON A CHIP

Guiding neuron development with planar surface gradients of substrate cues deposited using microfluidic devices

(2010) Larry J. Millet et al.   LAB ON A CHIP

Microfluidic cell culture systems for drug research

(2010) Min-Hsien Wu et al.   LAB ON A CHIP

A microfluidic platform for complete mammalian cell culture

(2010) Irena Barbulovic-Nad et al.   LAB ON A CHIP

A high-throughput microfluidic assay to study neurite response to growth factor gradients

(2010) Chandrasekhar R. Kothapalli et al.   LAB ON A CHIP

A microfluidic array with cellular valving for single cell co-culture

(2010) Jean-Philippe Frimat et al.   LAB ON A CHIP

Selective Breast Cancer Cell Capture, Culture, and Immunocytochemical Analysis Using Self-Assembled Magnetic Bead Patterns in a Microfluidic Chip

(2010) Venkataragavalu Sivagnanam et al.   LANGMUIR

Microfluidic cell culture system studies and computational fluid dynamics

(2010) Manguo Huang et al.   MATHEMATICAL AND COMPUTER MODELLING

Microfluidic tools for cell biological research

(2010) Guilhem Velve-Casquillas et al.   Nano Today

Development of high throughput microfluidic cell culture chip for perfusion 3-dimensional cell culture-based chemosensitivity assay

(2010) Min-Hsien Wu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Fabrication of patterned cell co-cultures on albumin-based substrate: Applications for microfluidic devices

(2009) H. Yamazoe et al.   Acta Biomaterialia

Microfluidic chip: Next-generation platform for systems biology

(2009) Xiaojun Feng et al.   ANALYTICA CHIMICA ACTA

The microwell control of embryoid body size in order to regulate cardiac differentiation of human embryonic stem cells

(2009) Jeffrey C. Mohr et al.   BIOMATERIALS

The culture and differentiation of amniotic stem cells using a microfluidic system

(2009) Huei-Wen Wu et al.   BIOMEDICAL MICRODEVICES

An agarose-based microfluidic platform with a gradient buffer for 3D chemotaxis studies

(2009) Ulrike Haessler et al.   BIOMEDICAL MICRODEVICES

Growth of primary embryo cells in a microculture system

(2009) Max Villa et al.   BIOMEDICAL MICRODEVICES

A microfluidic cell culture platform for real-time cellular imaging

(2009) Chia-Chun Hsieh et al.   BIOMEDICAL MICRODEVICES

An open-access microfluidic model for lung-specific functional studies at an air-liquid interface

(2009) Divya D. Nalayanda et al.   BIOMEDICAL MICRODEVICES

From the cellular perspective: exploring differences in the cellular baseline in macroscale and microfluidic cultures

(2009) Amy L. Paguirigan et al.   Integrative Biology

Hypoxia or in situ normoxia: The stem cell paradigm

(2009) Zoran Ivanovic   JOURNAL OF CELLULAR PHYSIOLOGY

Selective and tunable gradient device for cell culture and chemotaxis study

(2009) Dongshin Kim et al.   LAB ON A CHIP

The microfluidic palette: A diffusive gradient generator with spatio-temporal control

(2009) Javier Atencia et al.   LAB ON A CHIP

Simultaneous generation of chemical concentration and mechanical shear stress gradients using microfluidic osmotic flow comparable to interstitial flow

(2009) Joong Yull Park et al.   LAB ON A CHIP

Microfluidic culture of single human embryonic stem cell colonies

(2009) Luis Gerardo Villa-Diaz et al.   LAB ON A CHIP

Dielectrophoresis-based cell manipulation using electrodes on a reusable printed circuit board

(2009) Kidong Park et al.   LAB ON A CHIP

A microfluidic 3D hepatocyte chip for drug toxicity testing

(2009) Yi-Chin Toh et al.   LAB ON A CHIP

Macro- and microscale fluid flow systems for endothelial cell biology

(2009) Edmond W. K. Young et al.   LAB ON A CHIP

Differentiation of Neural Progenitor Cells in a Microfluidic Chip-Generated Cytokine Gradient

(2009) Joong Yull Park et al.   STEM CELLS

Multi-Molecular Gradients of Permissive and Inhibitory Cues Direct Neurite Outgrowth

(2008) Grace N. Li et al.   ANNALS OF BIOMEDICAL ENGINEERING

Cell Culture Models in Microfluidic Systems

(2008) Ivar Meyvantsson et al.   Annual Review of Analytical Chemistry

In vitro analysis of a hepatic device with intrinsic microvascular-based channels

(2008) Amedeo Carraro et al.   BIOMEDICAL MICRODEVICES

Generating steep, shear-free gradients of small molecules for cell culture

(2008) Taesung Kim et al.   BIOMEDICAL MICRODEVICES

A microfluidic cell array with individually addressable culture chambers

(2008) Hsiang-Yu Wang et al.   BIOSENSORS & BIOELECTRONICS

Pressure-driven perfusion culture microchamber array for a parallel drug cytotoxicity assay

(2008) Shinji Sugiura et al.   BIOTECHNOLOGY AND BIOENGINEERING

Bicompartmental device for dynamic cell coculture: Design, realisation and preliminary results

(2008) Gianni Ciofani et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Design of bioreactors for mesenchymal stem cell tissue engineering

(2008) Pankaj Godara et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

A microfluidics-based turning assay reveals complex growth cone responses to integrated gradients of substrate-bound ECM molecules and diffusible guidance cues

(2008) C. Joanne Wang et al.   LAB ON A CHIP

A platform for assessing chemotactic migration within a spatiotemporally defined 3D microenvironment

(2008) Vinay V. Abhyankar et al.   LAB ON A CHIP

Fabrication of a modular tissue construct in a microfluidic chip

(2008) Derek A. Bruzewicz et al.   LAB ON A CHIP

An integrated microfluidic culture device for quantitative analysis of human embryonic stem cells

(2008) Ken-ichiro Kamei et al.   LAB ON A CHIP

A multi-purpose microfluidic perfusion system with combinatorial choice of inputs, mixtures, gradient patterns, and flow rates

(2008) Gregory A. Cooksey et al.   LAB ON A CHIP

Fabrication of a microfluidic chip containing dam, weirs and gradient generator for studying cellular response to chemical modulation

(2008) Jing Ruan et al.   Materials Science & Engineering C-Materials for Biological Applications

Micro-bioreactor arrays for controlling cellular environments: Design principles for human embryonic stem cell applications

(2008) Elisa Cimetta et al.   METHODS

High glucose induces adipogenic differentiation of muscle-derived stem cells

(2008) P. Aguiari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of Human Embryonic Stem Cell Colony and Aggregate Size Heterogeneity Influences Differentiation Trajectories

(2008) Céline Liu Bauwens et al.   STEM CELLS

Engineered Microenvironments for Controlled Stem Cell Differentiation

(2008) Jason A. Burdick et al.   TISSUE ENGINEERING PART A

Three-Dimensional Cell Culture Matrices: State of the Art

(2008) Jungwoo Lee et al.   TISSUE ENGINEERING PART B-REVIEWS

Controlled differentiation of stem cells

(2007) Nathaniel S. Hwang et al.   ADVANCED DRUG DELIVERY REVIEWS

Radial flow hepatocyte bioreactor using stacked microfabricated grooved substrates

(2007) Jaesung Park et al.   BIOTECHNOLOGY AND BIOENGINEERING

Hepatogenic differentiation of mesenchymal stem cells using microfluidic chips

(2007) Xiuli Ju et al.   Biotechnology Journal

Biomolecular gradients in cell culture systems

(2007) Thomas M. Keenan et al.   LAB ON A CHIP