Porphyromonas gingivalis disturbs host–commensal homeostasis by changing complement function

On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier

(2017) Nicolas Dutzan et al.   IMMUNITY

The “ins and outs” of complement-driven immune responses

(2016) Simon Freeley et al.   IMMUNOLOGICAL REVIEWS

More than complementing Tolls: complement-Toll-like receptor synergy and crosstalk in innate immunity and inflammation

(2016) George Hajishengallis et al.   IMMUNOLOGICAL REVIEWS

Inhibition of pre-existing natural periodontitis in non-human primates by a locally administered peptide inhibitor of complement C3

(2016) Tomoki Maekawa et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Resolvin E1 Reverses Experimental Periodontitis and Dysbiosis

(2016) Chun-Teh Lee et al.   JOURNAL OF IMMUNOLOGY

Differential capacity for complement receptor-mediated immune evasion byPorphyromonas gingivalisdepending on the type of innate leukocyte

(2016) G. Hajishengallis et al.   Molecular Oral Microbiology

Dancing with the Stars: How Choreographed Bacterial Interactions Dictate Nososymbiocity and Give Rise to Keystone Pathogens, Accessory Pathogens, and Pathobionts

(2016) George Hajishengallis et al.   TRENDS IN MICROBIOLOGY

Hijacking Complement Regulatory Proteins for Bacterial Immune Evasion

(2016) Elise S. Hovingh et al.   Frontiers in Microbiology

Major neutrophil functions subverted by Porphyromonas gingivalis

(2016) Ingar Olsen et al.   Journal of Oral Microbiology

Porphyromonas gingivalis suppresses adaptive immunity in periodontitis, atherosclerosis, and Alzheimer’s disease

(2016) Ingar Olsen et al.   Journal of Oral Microbiology

Modulation of inflammasome activity by Porphyromonas gingivalis in periodontitis and associated systemic diseases

(2016) Ingar Olsen et al.   Journal of Oral Microbiology

Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention

(2015) Dimitrios C. Mastellos et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Complement

(2015) Juan Carlos Varela et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Complement therapeutics in inflammatory diseases: promising drug candidates for C3-targeted intervention

(2015) D.C. Mastellos et al.   Molecular Oral Microbiology

Basic biology and role of interleukin-17 in immunity and inflammation

(2015) Camille Zenobia et al.   PERIODONTOLOGY 2000

Dendritic cells: microbial clearance via autophagy and potential immunobiological consequences for periodontal disease

(2015) Ahmed R. El-Awady et al.   PERIODONTOLOGY 2000

Polymicrobial synergy and dysbiosis in inflammatory disease

(2015) Richard J. Lamont et al.   TRENDS IN MOLECULAR MEDICINE

Microbiome Profiles in Periodontitis in Relation to Host and Disease Characteristics

(2015) Bo-Young Hong et al.   PLoS One

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Porphyromonas gingivalis Manipulates Complement and TLR Signaling to Uncouple Bacterial Clearance from Inflammation and Promote Dysbiosis

(2014) Tomoki Maekawa et al.   Cell Host & Microbe

The Periodontal Pathogen Porphyromonas gingivalis Induces Expression of Transposases and Cell Death of Streptococcus mitis in a Biofilm Model

(2014) Ana E. Duran-Pinedo et al.   INFECTION AND IMMUNITY

Binding of Complement Inhibitor C4b-Binding Protein Contributes to Serum Resistance of Porphyromonas gingivalis

(2014) M. Potempa et al.   JOURNAL OF IMMUNOLOGY

Genetic and Intervention Studies Implicating Complement C3 as a Major Target for the Treatment of Periodontitis

(2014) T. Maekawa et al.   JOURNAL OF IMMUNOLOGY

Neutrophil homeostasis and inflammation: novel paradigms from studying periodontitis

(2014) G. Hajishengallis et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The inflammophilic character of the periodontitis-associated microbiota

(2014) G. Hajishengallis   Molecular Oral Microbiology

Defective Neutrophil Recruitment in Leukocyte Adhesion Deficiency Type I Disease Causes Local IL-17-Driven Inflammatory Bone Loss

(2014) N. M. Moutsopoulos et al.   Science Translational Medicine

The Oral Commensal Microbiota Bites Back through Nod1

(2013) Mike Curtis   Cell Host & Microbe

Suppression of T-Cell Chemokines by Porphyromonas gingivalis

(2013) Catherine E. Jauregui et al.   INFECTION AND IMMUNITY

The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation

(2013) Loreto Abusleme et al.   ISME Journal

Porphyromonas gingivalis: keeping the pathos out of the biont

(2013) Carla Cugini et al.   Journal of Oral Microbiology

Protease-dependent mechanisms of complement evasion by bacterial pathogens

(2012) Michal Potempa et al.   BIOLOGICAL CHEMISTRY

Proteomics of Streptococcus gordonii within a model developing oral microbial community

(2012) Erik L Hendrickson et al.   BMC MICROBIOLOGY

Complement and dysbiosis in periodontal disease

(2012) George Hajishengallis et al.   IMMUNOBIOLOGY

Porphyromonas gingivalis promotes Th17 inducing pathways in chronic periodontitis

(2012) Niki M. Moutsopoulos et al.   JOURNAL OF AUTOIMMUNITY

Porphyromonas gingivalisMediates Inflammasome Repression in Polymicrobial Cultures through a Novel Mechanism Involving Reduced Endocytosis

(2012) Debra J. Taxman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Porphyromonas gingivalis as a Potential Community Activist for Disease

(2012) R.P. Darveau et al.   JOURNAL OF DENTAL RESEARCH

Protective Role for TLR4 Signaling in Atherosclerosis Progression as Revealed by Infection with a Common Oral Pathogen

(2012) C. Hayashi et al.   JOURNAL OF IMMUNOLOGY

Streptococcus cristatus ArcA interferes with Porphyromonas gingivalis pathogenicity in mice

(2012) H. Xie et al.   JOURNAL OF PERIODONTAL RESEARCH

Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology

(2012) G. Hajishengallis et al.   Molecular Oral Microbiology

The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss

(2012) Mehmet A Eskan et al.   NATURE IMMUNOLOGY

The keystone-pathogen hypothesis

(2012) George Hajishengallis et al.   NATURE REVIEWS MICROBIOLOGY

Low-Abundance Biofilm Species Orchestrates Inflammatory Periodontal Disease through the Commensal Microbiota and Complement

(2011) George Hajishengallis et al.   Cell Host & Microbe

Interleukin-10 and Immunity against Prokaryotic and Eukaryotic Intracellular Pathogens

(2011) Joshua C. Cyktor et al.   INFECTION AND IMMUNITY

Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing

(2011) Ann L Griffen et al.   ISME Journal

The pathogenic persona of community-associated oral streptococci

(2011) Sarah E. Whitmore et al.   MOLECULAR MICROBIOLOGY

Structural Dissection andIn VivoEffectiveness of a Peptide Inhibitor ofPorphyromonas gingivalisAdherence toStreptococcus gordonii

(2010) Carlo Amorin Daep et al.   INFECTION AND IMMUNITY

Bacterial diversity in the oral cavity of 10 healthy individuals

(2010) Elisabeth M Bik et al.   ISME Journal

The Human Oral Microbiome

(2010) F. E. Dewhirst et al.   JOURNAL OF BACTERIOLOGY

The C5a Receptor Impairs IL-12-Dependent Clearance of Porphyromonas gingivalis and Is Required for Induction of Periodontal Bone Loss

(2010) S. Liang et al.   JOURNAL OF IMMUNOLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

An Integrated View of Humoral Innate Immunity: Pentraxins as a Paradigm

(2009) Barbara Bottazzi et al.   Annual Review of Immunology

Proteomics of Porphyromonas gingivalis within a model oral microbial community

(2009) Masae Kuboniwa et al.   BMC MICROBIOLOGY

Defining the healthy "core microbiome" of oral microbial communities

(2009) Egija Zaura et al.   BMC MICROBIOLOGY

The Oral Microbial Consortium's Interaction with the Periodontal Innate Defense System

(2009) Richard P. Darveau   DNA AND CELL BIOLOGY

Negative Correlation of Distributions of Streptococcus cristatus and Porphyromonas gingivalis in Subgingival Plaque

(2009) B.-y. Wang et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Porphyromonas gingivalis–host interactions: open war or intelligent guerilla tactics?

(2009) George Hajishengallis   MICROBES AND INFECTION

Complement evasion strategies of pathogens—Acquisition of inhibitors and beyond

(2009) Anna M. Blom et al.   MOLECULAR IMMUNOLOGY

Interpain A, a Cysteine Proteinase from Prevotella intermedia, Inhibits Complement by Degrading Complement Factor C3

(2009) Michal Potempa et al.   PLoS Pathogens

Role of Porphyromonas gingivalis SerB in Gingival Epithelial Cell Cytoskeletal Remodeling and Cytokine Production

(2008) Y. Hasegawa et al.   INFECTION AND IMMUNITY

Porphyromonas gingivalis RgpA-Kgp Proteinase-Adhesin Complexes Penetrate Gingival Tissue and Induce Proinflammatory Cytokines or Apoptosis in a Concentration-Dependent Manner

(2008) N. M. O'Brien-Simpson et al.   INFECTION AND IMMUNITY

Identification of a Second Lipopolysaccharide in Porphyromonas gingivalis W50

(2008) M. Rangarajan et al.   JOURNAL OF BACTERIOLOGY

Degradation of Human α- and β-Defensins by Culture Supernatants of Porphyromonas gingivalis Strain 381

(2008) M.D. Carlisle et al.   Journal of Innate Immunity

Corruption of Innate Immunity by Bacterial Proteases

(2008) Jan Potempa et al.   Journal of Innate Immunity

Complement evasion by human pathogens

(2008) John D. Lambris et al.   NATURE REVIEWS MICROBIOLOGY