Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy
Authors
Keywords
-
Journal
Frontiers in Neuroscience
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-12-12
DOI
10.3389/fnins.2017.00680
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Microglia Demonstrate Age-Dependent Interaction with Amyloid-β Fibrils
- (2018) Angela Marie Floden et al. JOURNAL OF ALZHEIMERS DISEASE
- Glutaminyl Cyclase in Human Cortex: Correlation with (pGlu)-Amyloid-β Load and Cognitive Decline in Alzheimer's Disease
- (2018) Markus Morawski et al. JOURNAL OF ALZHEIMERS DISEASE
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
- Old Maids: Aging and Its Impact on Microglia Function
- (2017) Edward Koellhoffer et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A split-luciferase complementation, real-time reporting assay enables monitoring of the disease-associated transmembrane protein TREM2 in live cells
- (2017) Megan M. Varnum et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Microglia in prion diseases
- (2017) Adriano Aguzzi et al. JOURNAL OF CLINICAL INVESTIGATION
- Soluble TREM2 induces inflammatory responses and enhances microglial survival
- (2017) Li Zhong et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy
- (2017) Shane M. Bemiller et al. Molecular Neurodegeneration
- Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease
- (2017) Zhuoran Yin et al. NEUROBIOLOGY OF AGING
- Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift
- (2017) Yasir N. Jassam et al. NEURON
- TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy
- (2017) Cheryl E. G. Leyns et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RIPK1 mediates a disease-associated microglial response in Alzheimer’s disease
- (2017) Dimitry Ofengeim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An environment-dependent transcriptional network specifies human microglia identity
- (2017) David Gosselin et al. SCIENCE
- The Lifespan and Turnover of Microglia in the Human Brain
- (2017) Pedro Réu et al. Cell Reports
- TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway
- (2017) Li Zhong et al. Frontiers in Aging Neuroscience
- Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation
- (2017) Cláudia Caldeira et al. Frontiers in Aging Neuroscience
- Curcumin Protects against Ischemic Stroke by Titrating Microglia/Macrophage Polarization
- (2017) Zongjian Liu et al. Frontiers in Aging Neuroscience
- Exosomes: Origins and Therapeutic Potential for Neurodegenerative Disease
- (2017) Diana K. Sarko et al. Frontiers in Neuroscience
- Exosomes, an Unmasked Culprit in Neurodegenerative Diseases
- (2017) Federico N. Soria et al. Frontiers in Neuroscience
- M2 Phenotype Microglia-derived Cytokine Stimulates Proliferation and Neuronal Differentiation of Endogenous Stem Cells in Ischemic Brain
- (2017) Ja Yong Choi et al. Experimental Neurobiology
- RVX-208, a BET-inhibitor for treating atherosclerotic cardiovascular disease, raises ApoA-I/HDL and represses pathways that contribute to cardiovascular disease
- (2016) Dean Gilham et al. ATHEROSCLEROSIS
- Signal transduction and epigenetic mechanisms in the control of microglia activation during neuroinflammation
- (2016) Bozena Kaminska et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology
- (2016) Adrian Olmos-Alonso et al. BRAIN
- Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology
- (2016) Elizabeth E. Spangenberg et al. BRAIN
- Exosome secretion is a key pathway for clearance of pathological TDP-43
- (2016) Yohei Iguchi et al. BRAIN
- TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance
- (2016) Xianyuan Xiang et al. EMBO Molecular Medicine
- P2Y12receptor is expressed on human microglia under physiological conditions throughout development and is sensitive to neuroinflammatory diseases
- (2016) Alexander Mildner et al. GLIA
- Dark microglia: A new phenotype predominantly associated with pathological states
- (2016) Kanchan Bisht et al. GLIA
- Increase of α-Secretase ADAM10 in Platelets Along Cognitively Healthy Aging
- (2016) Florian Schuck et al. JOURNAL OF ALZHEIMERS DISEASE
- AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics
- (2016) Susanna Eketjäll et al. JOURNAL OF ALZHEIMERS DISEASE
- Stimulating the Release of Exosomes Increases the Intercellular Transfer of Prions
- (2016) Belinda B. Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease
- (2016) Jeff Sevigny et al. NATURE
- Age-related myelin degradation burdens the clearance function of microglia during aging
- (2016) Shima Safaiyan et al. NATURE NEUROSCIENCE
- Microglial brain region−dependent diversity and selective regional sensitivities to aging
- (2016) Kathleen Grabert et al. NATURE NEUROSCIENCE
- A polarizing question: do M1 and M2 microglia exist?
- (2016) Richard M Ransohoff NATURE NEUROSCIENCE
- Extracellular vesicles in neurodegenerative disease — pathogenesis to biomarkers
- (2016) Alexander G. Thompson et al. Nature Reviews Neurology
- Extracellular vesicles round off communication in the nervous system
- (2016) Vivian Budnik et al. NATURE REVIEWS NEUROSCIENCE
- Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation
- (2016) Honghua Zheng et al. NEUROBIOLOGY OF AGING
- TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy
- (2016) Peng Yuan et al. NEURON
- Microglial TNF-α Suppresses Cocaine-Induced Plasticity and Behavioral Sensitization
- (2016) Gil M. Lewitus et al. NEURON
- Microglia development follows a stepwise program to regulate brain homeostasis
- (2016) O. Matcovitch-Natan et al. SCIENCE
- Complement and microglia mediate early synapse loss in Alzheimer mouse models
- (2016) S. Hong et al. SCIENCE
- How Do Meningeal Lymphatic Vessels Drain the CNS?
- (2016) Daniel Raper et al. TRENDS IN NEUROSCIENCES
- Microglial P2Y12 is necessary for synaptic plasticity in mouse visual cortex
- (2016) G. O. Sipe et al. Nature Communications
- Discovery of novel PDE9 inhibitors capable of inhibiting Aβ aggregation as potential candidates for the treatment of Alzheimer’s disease
- (2016) Tao Su et al. Scientific Reports
- Age-related changes in behavior in C57BL/6J mice from young adulthood to middle age
- (2016) Hirotaka Shoji et al. Molecular Brain
- Preclinical Assessment of Young Blood Plasma for Alzheimer Disease
- (2016) Jinte Middeldorp et al. JAMA Neurology
- c-Jun N-terminal Kinase (JNK) Signaling as a Therapeutic Target for Alzheimer’s Disease
- (2016) Ramon Yarza et al. Frontiers in Pharmacology
- An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic A 42 aggregates linked with Alzheimers disease
- (2016) J. Habchi et al. Science Advances
- Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study
- (2015) Massimo S. Fiandaca et al. Alzheimers & Dementia
- Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement
- (2015) Sebastian Altenhöfer et al. ANTIOXIDANTS & REDOX SIGNALING
- Blockade of exosome generation with GW4869 dampens the sepsis-induced inflammation and cardiac dysfunction
- (2015) Kobina Essandoh et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System
- (2015) Julia Bruttger et al. IMMUNITY
- Cellular Models of Aggregation-dependent Template-directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer Disease
- (2015) Charles R. Harrington et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TREM2 deficiency eliminates TREM2+inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models
- (2015) Taylor R. Jay et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Arginase 1+ microglia reduce Aβ plaque deposition during IL-1β-dependent neuroinflammation
- (2015) Jonathan D. Cherry et al. Journal of Neuroinflammation
- Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice
- (2015) Nabil N. Dagher et al. Journal of Neuroinflammation
- miR-155 Is Essential for Inflammation-Induced Hippocampal Neurogenic Dysfunction
- (2015) M. E. Woodbury et al. JOURNAL OF NEUROSCIENCE
- Novel Molecular Insights into Classical and Alternative Activation States of Microglia as Revealed by Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)-based Proteomics
- (2015) Harris Bell-Temin et al. MOLECULAR & CELLULAR PROTEOMICS
- Structural and functional features of central nervous system lymphatic vessels
- (2015) Antoine Louveau et al. NATURE
- Proteostasis and aging
- (2015) Susmita Kaushik et al. NATURE MEDICINE
- Depletion of microglia and inhibition of exosome synthesis halt tau propagation
- (2015) Hirohide Asai et al. NATURE NEUROSCIENCE
- Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex
- (2015) Claudia C. Wehrspaun et al. NEUROBIOLOGY OF AGING
- The anti-inflammatory glycoprotein, CD200, restores neurogenesis and enhances amyloid phagocytosis in a mouse model of Alzheimer's disease
- (2015) Megan M. Varnum et al. NEUROBIOLOGY OF AGING
- Age- and location-related changes in microglial function
- (2015) Rodney M. Ritzel et al. NEUROBIOLOGY OF AGING
- Etanercept in Alzheimer disease: A randomized, placebo-controlled, double-blind, phase 2 trial
- (2015) J. Butchart et al. NEUROLOGY
- Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
- (2015) Axel Montagne et al. NEURON
- A Phase 1 Trial of TPI 287 as a Single Agent and in Combination With Temozolomide in Patients with Refractory or Recurrent Neuroblastoma or Medulloblastoma
- (2015) Deanna Mitchell et al. PEDIATRIC BLOOD & CANCER
- Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice
- (2015) Byung Hee Han et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alternatively activated microglia and macrophages in the central nervous system
- (2015) Rafael Franco et al. PROGRESS IN NEUROBIOLOGY
- Exosomes and their roles in immune regulation and cancer
- (2015) David W. Greening et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- A high calorie diet causes memory loss, metabolic syndrome and oxidative stress into hippocampus and temporal cortex of rats
- (2015) Samuel Treviño et al. SYNAPSE
- Role of TGFβ signaling in the pathogenesis of Alzheimer’s disease
- (2015) Rommy von Bernhardi et al. Frontiers in Cellular Neuroscience
- Microglial cell dysregulation in brain aging and neurodegeneration
- (2015) Rommy von Bernhardi et al. Frontiers in Aging Neuroscience
- Amyloid β-protein oligomers upregulate the β-secretase, BACE1, through a post-translational mechanism involving its altered subcellular distribution in neurons
- (2015) Naomi Mamada et al. Molecular Brain
- Microglial dysfunction in brain aging and Alzheimer's disease
- (2014) Kira Irving Mosher et al. BIOCHEMICAL PHARMACOLOGY
- Age-dependent changes on TGFβ1 Smad3 pathway modify the pattern of microglial cell activation
- (2014) Juan E. Tichauer et al. BRAIN BEHAVIOR AND IMMUNITY
- TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation
- (2014) Priyanka Nair-Gupta et al. CELL
- Pattern recognition receptors and central nervous system repair
- (2014) Kristina A. Kigerl et al. EXPERIMENTAL NEUROLOGY
- Oxidative damage to mitochondria at the nodes of Ranvier precedes axon degeneration in ex vivo transected axons
- (2014) Helena Bros et al. EXPERIMENTAL NEUROLOGY
- NADPH oxidase- and mitochondria-derived reactive oxygen species in proinflammatory microglial activation: a bipartisan affair?
- (2014) Evan A. Bordt et al. FREE RADICAL BIOLOGY AND MEDICINE
- A Food and Drug Administration-approved Asthma Therapeutic Agent Impacts Amyloid β in the Brain in a Transgenic Model of Alzheimer Disease
- (2014) Yukiko Hori et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyloid-β Pathology andAPOEGenotype Modulate Retinoid X Receptor Agonist Activityin Vivo
- (2014) Leon M. Tai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neuroinflammation and M2 microglia: the good, the bad, and the inflamed
- (2014) Jonathan D Cherry et al. Journal of Neuroinflammation
- Phagocytosis of Microglia in the Central Nervous System Diseases
- (2014) Ruying Fu et al. MOLECULAR NEUROBIOLOGY
- Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2
- (2014) Jason D Ulrich et al. Molecular Neurodegeneration
- Erratum: Corrigendum: Identification of a unique TGF-β–dependent molecular and functional signature in microglia
- (2014) Oleg Butovsky et al. NATURE NEUROSCIENCE
- Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
- (2014) Monica R.P. Elmore et al. NEURON
- Microglial Dynamics and Role in the Healthy and Diseased Brain
- (2014) Diego Gomez-Nicola et al. NEUROSCIENTIST
- Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease
- (2014) Rachelle S. Doody et al. NEW ENGLAND JOURNAL OF MEDICINE
- Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers II: Sigma-2/PGRMC1 Receptors Mediate Abeta 42 Oligomer Binding and Synaptotoxicity
- (2014) Nicholas J. Izzo et al. PLoS One
- TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
- (2014) G. Kleinberger et al. Science Translational Medicine
- Degradation of amyloid beta by human induced pluripotent stem cell-derived macrophages expressing Neprilysin-2
- (2014) Koutaro Takamatsu et al. Stem Cell Research
- Lost after translation: missorting of Tau protein and consequences for Alzheimer disease
- (2014) Hans Zempel et al. TRENDS IN NEUROSCIENCES
- Microglia change from a reactive to an age-like phenotype with the time in culture
- (2014) Cláudia Caldeira et al. Frontiers in Cellular Neuroscience
- Fyn kinase inhibition as a novel therapy for Alzheimer’s disease
- (2014) Haakon B Nygaard et al. Alzheimers Research & Therapy
- First-in-man tau vaccine targeting structural determinants essential for pathological tau–tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer’s disease model
- (2014) Eva Kontsekova et al. Alzheimers Research & Therapy
- Homeostatic and injury-induced microglia behavior in the aging brain
- (2013) Jasmin K. Hefendehl et al. AGING CELL
- Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro
- (2013) Vibol Chhor et al. BRAIN BEHAVIOR AND IMMUNITY
- Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
- (2013) Christopher N. Parkhurst et al. CELL
- Role of Microglia in CNS Autoimmunity
- (2013) Tobias Goldmann et al. Clinical & Developmental Immunology
- NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration
- (2013) Liya Qin et al. GLIA
- Effect of Treatment for 12 Weeks With Rilapladib, a Lipoprotein-Associated Phospholipase A2 Inhibitor, on Arterial Inflammation as Assessed With 18F-Fluorodeoxyglucose-Positron Emission Tomography Imaging
- (2013) Ahmed Tawakol et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial
- (2013) Richard Dodel et al. LANCET NEUROLOGY
- Triggers and Effectors of Oxidative Stress at Blood-Brain Barrier Level: Relevance for Brain Ageing and Neurodegeneration
- (2013) Ana-Maria Enciu et al. Oxidative Medicine and Cellular Longevity
- Long-Term Treatment of Thalidomide Ameliorates Amyloid-Like Pathology through Inhibition of β-Secretase in a Mouse Model of Alzheimer’s Disease
- (2013) Ping He et al. PLoS One
- Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy
- (2013) Clara Theunis et al. PLoS One
- Neuronal Synapse Formation Induced by Microglia and Interleukin 10
- (2013) So-Hee Lim et al. PLoS One
- TGF Receptor Mutations Impose a Strong Predisposition for Human Allergic Disease
- (2013) P. A. Frischmeyer-Guerrerio et al. Science Translational Medicine
- Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration
- (2013) V. Hugh Perry et al. Seminars in Immunopathology
- Origin and differentiation of microglia
- (2013) Florent Ginhoux et al. Frontiers in Cellular Neuroscience
- Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis
- (2013) Amanda Sierra et al. Frontiers in Cellular Neuroscience
- Quantitating the subtleties of microglial morphology with fractal analysis
- (2013) Audrey Karperien et al. Frontiers in Cellular Neuroscience
- Microglial aging in the healthy CNS: phenotypes, drivers, and rejuvenation
- (2013) Wai T. Wong Frontiers in Cellular Neuroscience
- Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease
- (2013) Termpanit Chalermpalanupap et al. Alzheimers Research & Therapy
- Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials
- (2012) Alexander V. Vlassov et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer
- (2012) Jie Song et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Orchestrating transcriptional control of adult neurogenesis
- (2012) J. Hsieh GENES & DEVELOPMENT
- Purinergic receptors in microglia: Functional modal shifts of microglia mediated by P2 and P1 receptors
- (2012) Schuichi Koizumi et al. GLIA
- Effects of aging and sensory loss on glial cells in mouse visual and auditory cortices
- (2012) Marie-Ève Tremblay et al. GLIA
- Microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial-neuronal interactions
- (2012) Emma L. Mead et al. JOURNAL OF NEUROCHEMISTRY
- Minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology
- (2012) Maria Teresa Ferretti et al. Journal of Neuroinflammation
- Neuroprotective function for ramified microglia in hippocampal excitotoxicity
- (2012) Jonathan Vinet et al. Journal of Neuroinflammation
- Posiphen as a candidate drug to lower CSF amyloid precursor protein, amyloid-β peptide and τ levels: target engagement, tolerability and pharmacokinetics in humans
- (2012) Maria L Maccecchini et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Microglia Modulate Hippocampal Neural Precursor Activity in Response to Exercise and Aging
- (2012) J. Vukovic et al. JOURNAL OF NEUROSCIENCE
- Transgenic APP expression during postnatal development causes persistent locomotor hyperactivity in the adult
- (2012) Shaefali P Rodgers et al. Molecular Neurodegeneration
- Role of common and rare APP DNA sequence variants in Alzheimer disease
- (2012) B. V. Hooli et al. NEUROLOGY
- Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
- (2012) Dorothy P. Schafer et al. NEURON
- Morphological and genetic activation of microglia after diffuse traumatic brain injury in the rat
- (2012) T. Cao et al. NEUROSCIENCE
- Microglia in the developing brain: A potential target with lifetime effects
- (2012) G. Jean Harry et al. NEUROTOXICOLOGY
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mechanism of Oxidative Stress in Neurodegeneration
- (2012) Sonia Gandhi et al. Oxidative Medicine and Cellular Longevity
- GFAP Isoforms in Adult Mouse Brain with a Focus on Neurogenic Astrocytes and Reactive Astrogliosis in Mouse Models of Alzheimer Disease
- (2012) Willem Kamphuis et al. PLoS One
- Eaten alive! Cell death by primary phagocytosis: ‘phagoptosis’
- (2012) Guy C. Brown et al. TRENDS IN BIOCHEMICAL SCIENCES
- Emerging Roles of Exosomes in Neuron–Glia Communication
- (2012) Carsten Frühbeis et al. Frontiers in Physiology
- Cross-reactive broadly neutralizing antibodies: timing is everything
- (2012) Zelda Euler et al. Frontiers in Immunology
- Extended results of the Alzheimer’s disease anti-inflammatory prevention trial
- (2011) John C. Breitner et al. Alzheimers & Dementia
- Neprilysin-2 Is an Important β-Amyloid Degrading Enzyme
- (2011) Daniel Hafez et al. AMERICAN JOURNAL OF PATHOLOGY
- Age related changes in microglial phenotype vary between CNS regions: Grey versus white matter differences
- (2011) Adam D. Hart et al. BRAIN BEHAVIOR AND IMMUNITY
- Evidence that Microglia Mediate the Neurobiological Effects of Chronic Psychological Stress on the Medial Prefrontal Cortex
- (2011) M. Hinwood et al. CEREBRAL CORTEX
- Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential
- (2011) Mark L. Hanke et al. CLINICAL SCIENCE
- γ-Secretase Inhibitors and Modulators for the Treatment of Alzheimer's Disease: Disappointments and Hopes
- (2011) Bruno P. Imbimbo et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Purinergic systems, neuropathic pain and the role of microglia
- (2011) Kazuhide Inoue et al. EXPERIMENTAL NEUROLOGY
- Role of microglia in CNS inflammation
- (2011) Manuel B. Graeber et al. FEBS LETTERS
- Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease
- (2011) Sudad Saman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Aβ-Degrading Enzymes: Potential for Treatment of Alzheimer Disease
- (2011) James Scott Miners et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- The Second-Generation Active A Immunotherapy CAD106 Reduces Amyloid Accumulation in APP Transgenic Mice While Minimizing Potential Side Effects
- (2011) C. Wiessner et al. JOURNAL OF NEUROSCIENCE
- CX3CR1 Deficiency Leads to Impairment of Hippocampal Cognitive Function and Synaptic Plasticity
- (2011) J. T. Rogers et al. JOURNAL OF NEUROSCIENCE
- Microglial phagocytosis induced by fibrillar β-amyloid is attenuated by oligomeric β-amyloid: implications for Alzheimer's disease
- (2011) Xiao-dong Pan et al. Molecular Neurodegeneration
- The age-related deficit in LTP is associated with changes in perfusion and blood-brain barrier permeability
- (2011) Christoph W. Blau et al. NEUROBIOLOGY OF AGING
- Microglial Morphology and Dynamic Behavior Is Regulated by Ionotropic Glutamatergic and GABAergic Neurotransmission
- (2011) Aurora M. Fontainhas et al. PLoS One
- A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells
- (2011) A. W. Kao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
- (2011) R. C. Paolicelli et al. SCIENCE
- Age-related alterations in the dynamic behavior of microglia
- (2010) Mausam R. Damani et al. AGING CELL
- Aβ Accelerates the Spatiotemporal Progression of Tau Pathology and Augments Tau Amyloidosis in an Alzheimer Mouse Model
- (2010) David E. Hurtado et al. AMERICAN JOURNAL OF PATHOLOGY
- Physiological and health implications of a sedentary lifestyle
- (2010) Mark Stephen Tremblay et al. Applied Physiology Nutrition and Metabolism
- Mechanisms Underlying Inflammation in Neurodegeneration
- (2010) Christopher K. Glass et al. CELL
- Amyloid oligomers: formation and toxicity of Aβ oligomers
- (2010) Masafumi Sakono et al. FEBS Journal
- Fractalkine Attenuates Excito-neurotoxicity via Microglial Clearance of Damaged Neurons and Antioxidant Enzyme Heme Oxygenase-1 Expression
- (2010) Mariko Noda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums
- (2010) Kodi S. Ravichandran JOURNAL OF EXPERIMENTAL MEDICINE
- TLR2 activation inhibits embryonic neural progenitor cell proliferation
- (2010) Eitan Okun et al. JOURNAL OF NEUROCHEMISTRY
- The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases
- (2010) Grégory Conductier et al. JOURNAL OF NEUROIMMUNOLOGY
- Inhibition of neutral sphingomyelinase-2 perturbs brain sphingolipid balance and spatial memory in mice
- (2010) Nino Tabatadze et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease
- (2010) Martin Fuhrmann et al. NATURE NEUROSCIENCE
- Duplication of amyloid precursor protein (APP), but not prion protein (PRNP) gene is a significant cause of early onset dementia in a large UK series
- (2010) Daniel McNaughton et al. NEUROBIOLOGY OF AGING
- Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function
- (2010) eMalick G. Njie et al. NEUROBIOLOGY OF AGING
- Evidence for widespread adaptive evolution of gene expression in budding yeast
- (2010) H. B. Fraser et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microglia and neuroprotection: From in vitro studies to therapeutic applications
- (2010) Elisabetta Polazzi et al. PROGRESS IN NEUROBIOLOGY
- Decreased Clearance of CNS -Amyloid in Alzheimer's Disease
- (2010) K. G. Mawuenyega et al. SCIENCE
- Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
- (2010) F. Ginhoux et al. SCIENCE
- Are NSAIDs useful to treat Alzheimer’s disease or mild cognitive impairment?
- (2010) Imbimbo Frontiers in Aging Neuroscience
- Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer’s disease
- (2009) Wolfgang J. Streit et al. ACTA NEUROPATHOLOGICA
- Microglial Physiology: Unique Stimuli, Specialized Responses
- (2009) Richard M. Ransohoff et al. Annual Review of Immunology
- CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system
- (2009) Alexander Mildner et al. BRAIN
- CHF5074, a novel γ-secretase modulator, attenuates brain β-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease
- (2009) BP Imbimbo et al. BRITISH JOURNAL OF PHARMACOLOGY
- GABAergic Interneuron Dysfunction Impairs Hippocampal Neurogenesis in Adult Apolipoprotein E4 Knockin Mice
- (2009) Gang Li et al. Cell Stem Cell
- Clearance of Amyloid-β Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimers Disease
- (2009) R. Deane et al. CNS & Neurological Disorders-Drug Targets
- Fractalkine-induced activation of the phosphatidylinositol-3 kinase pathway attentuates microglial activationin vivoandin vitro
- (2009) Anthony Lyons et al. JOURNAL OF NEUROCHEMISTRY
- Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain
- (2009) Carol A. Colton Journal of Neuroimmune Pharmacology
- Emergence and pandemic potential of swine-origin H1N1 influenza virus
- (2009) Gabriele Neumann et al. NATURE
- Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia
- (2009) Stefan A Grathwohl et al. NATURE NEUROSCIENCE
- Fractalkine and CX3CR1 regulate hippocampal neurogenesis in adult and aged rats
- (2009) Adam D. Bachstetter et al. NEUROBIOLOGY OF AGING
- Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease
- (2009) Velandai Srikanth et al. NEUROBIOLOGY OF AGING
- Acute in vivo exposure to interferon- enables resident brain dendritic cells to become effective antigen presenting cells
- (2009) A. Gottfried-Blackmore et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Dose-Escalation Study of Aerosolized Sargramostim in the Treatment of Metastatic Melanoma
- (2008) Svetomir N. Markovic et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival
- (2008) L. Landsman et al. BLOOD
- CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis
- (2008) L. A. Truman et al. BLOOD
- Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1β and anti-inflammatory IL-10 cytokines
- (2008) Christopher J. Henry et al. BRAIN BEHAVIOR AND IMMUNITY
- LPS/TLR4 signal transduction pathway
- (2008) Yong-Chen Lu et al. CYTOKINE
- Neuroinflammation and cognitive function in aged mice following minor surgery
- (2008) H.A. Rosczyk et al. EXPERIMENTAL GERONTOLOGY
- Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: A potential mechanism leading to chronic inflammation
- (2008) Douglas G. Walker et al. EXPERIMENTAL NEUROLOGY
- TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice
- (2008) Stefanie Frank et al. GLIA
- Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
- (2008) Jing-Ji Jin et al. Journal of Neuroinflammation
- Inflammaging as a prodrome to Alzheimer's disease
- (2008) Brian Giunta et al. Journal of Neuroinflammation
- Reverse of Age-Dependent Memory Impairment and Mitochondrial DNA Damage in Microglia by an Overexpression of Human Mitochondrial Transcription Factor A in Mice
- (2008) Y. Hayashi et al. JOURNAL OF NEUROSCIENCE
- Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial
- (2008) Clive Holmes et al. LANCET
- The NALP3 inflammasome is involved in the innate immune response to amyloid-β
- (2008) Annett Halle et al. NATURE IMMUNOLOGY
- Activation of the Amyloid Cascade by Intracerebroventricular Injection of the Protease Inhibitor Phosphoramidon
- (2008) Yotam Nisemblat et al. Neurodegenerative Diseases
- Protective effects of NSAIDs on the development of Alzheimer disease
- (2008) Steven C. Vlad et al. NEUROLOGY
- Plasticity and repair in the post-ischemic brain
- (2008) Massimiliano Di Filippo et al. NEUROPHARMACOLOGY
- Voxel-based mapping of brain gray matter volume and glucose metabolism profiles in normal aging
- (2007) Grégoria Kalpouzos et al. NEUROBIOLOGY OF AGING
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now