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Title
3D Miniaturization of Human Organs for Drug Discovery
Authors
Keywords
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Journal
Advanced Healthcare Materials
Volume 7, Issue 2, Pages 1700551
Publisher
Wiley
Online
2017-09-08
DOI
10.1002/adhm.201700551
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- (2017) Hyeryeon Jeon et al. Gut and Liver
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- (2017) Lawrence Vernetti et al. Scientific Reports
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- (2016) Kristin M. Warren et al. ACS Applied Materials & Interfaces
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- (2016) Xuan Zhou et al. ACS Applied Materials & Interfaces
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- (2016) Xuyu Qian et al. CELL
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- (2016) Kai Kretzschmar et al. DEVELOPMENTAL CELL
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- Liver metastases: Microenvironments and ex-vivo models
- (2016) Amanda M Clark et al. EXPERIMENTAL BIOLOGY AND MEDICINE
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- (2016) E. L. Jackson et al. Integrative Biology
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- (2016) Jing-Zhang Wang et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
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- (2016) Arnout Schepers et al. LAB ON A CHIP
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- (2016) Jeong Hun Park et al. Tissue Engineering and Regenerative Medicine
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