Epigenetic Regulatory Mechanisms Induced by Resveratrol

Resveratrol inhibits inflammatory signaling implicated in ionizing radiation-induced premature ovarian failure through antagonistic crosstalk between silencing information regulator 1 (SIRT1) and poly(ADP-ribose) polymerase 1 (PARP-1)

(2016) Riham Soliman Said et al.   BIOCHEMICAL PHARMACOLOGY

Histone demethylase LSD1 controls the phenotypic plasticity of cancer cells

(2016) Shinjiro Hino et al.   CANCER SCIENCE

Stilbenoids remodel the DNA methylation patterns in breast cancer cells and inhibit oncogenic NOTCH signaling through epigenetic regulation of MAML2 transcriptional activity

(2016) Katarzyna Lubecka et al.   CARCINOGENESIS

Inhibitors of LSD1 as a potential therapy for acute myeloid leukemia

(2016) Amanda Przespolewski et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Sirtuin 1 and 7 mediate resveratrol-induced recovery from hyper-anxiety in high-fructose-fed prediabetic rats

(2016) B Raghunath Reddy et al.   JOURNAL OF BIOSCIENCES

Understanding the Complexity of Epigenetic Target Space

(2016) Vineet Pande   JOURNAL OF MEDICINAL CHEMISTRY

Resveratrol reverses morphine-induced neuroinflammation in morphine-tolerant rats by reversal HDAC1 expression

(2016) Ru-Yin Tsai et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

SirT1 activator represses the transcription of TNF-α in THP-1 cells of a sepsis model via deacetylation of H4K16

(2016) Guo-Dong Chen et al.   Molecular Medicine Reports

Resveratrol inhibits adventitial fibroblast proliferation and induces cell apoptosis through the SIRT1 pathway

(2016) Lin Ling et al.   Molecular Medicine Reports

Resveratrol affects DNA damage induced by ionizing radiation in human lymphocytes in vitro

(2016) Emiliano Basso et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Resveratrol Enhances Autophagic Flux and Promotes Ox-LDL Degradation in HUVECs via Upregulation of SIRT1

(2016) Yanlin Zhang et al.   Oxidative Medicine and Cellular Longevity

Sirt1 is essential for resveratrol enhancement of hypoxia-induced autophagy in the type 2 diabetic nephropathy rat

(2016) Liqun Ma et al.   PATHOLOGY RESEARCH AND PRACTICE

Epigenetic regulation of active Chinese herbal components for cancer prevention and treatment: A follow-up review

(2016) Zhiying Huang et al.   PHARMACOLOGICAL RESEARCH

A Novel Combinatorial Epigenetic Therapy Using Resveratrol and Pterostilbene for Restoring Estrogen Receptor-α (ERα) Expression in ERα-Negative Breast Cancer Cells

(2016) Rishabh Kala et al.   PLoS One

Resveratrol Protects against TNF-α-Induced Injury in Human Umbilical Endothelial Cells through Promoting Sirtuin-1-Induced Repression of NF-KB and p38 MAPK

(2016) Wei Pan et al.   PLoS One

Resveratrol and Cardiovascular Diseases

(2016) Dominique Bonnefont-Rousselot   Nutrients

Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells

(2016) Constanze Buhrmann et al.   Nutrients

Unraveling the Anticancer Effect of Curcumin and Resveratrol

(2016) Aline Pavan et al.   Nutrients

Sirtuins Link Inflammation and Metabolism

(2016) Vidula T. Vachharajani et al.   Journal of Immunology Research

BRCA1 inhibits AR–mediated proliferation of breast cancer cells through the activation of SIRT1

(2016) Wenwen Zhang et al.   Scientific Reports

Activation of SIRT3 by resveratrol ameliorates cardiac fibrosis and improves cardiac function via the TGF-β/Smad3 pathway

(2015) Tongshuai Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Exploring new ways of regulation by resveratrol involving miRNAs, with emphasis on inflammation

(2015) Norbert Latruffe et al.   Annals of the New York Academy of Sciences

Epigenetic potential of resveratrol and analogs in preclinical models of prostate cancer

(2015) Avinash Kumar et al.   Annals of the New York Academy of Sciences

Direct molecular targets of resveratrol: identifying key interactions to unlock complex mechanisms

(2015) Robert G. Britton et al.   Annals of the New York Academy of Sciences

Resveratrol and obesity: Can resveratrol relieve metabolic disturbances?

(2015) Marlies de Ligt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Lifespan and healthspan extension by resveratrol

(2015) Khushwant S. Bhullar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The molecular targets of resveratrol

(2015) Sameer S. Kulkarni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Neuroprotective action of resveratrol

(2015) Stéphane Bastianetto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Resveratrol regulates PTEN/Akt pathway through inhibition of MTA1/HDAC unit of the NuRD complex in prostate cancer

(2015) Swati Dhar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Epigenetic-based combinatorial resveratrol and pterostilbene alters DNA damage response by affecting SIRT1 and DNMT enzyme expression, including SIRT1-dependent γ-H2AX and telomerase regulation in triple-negative breast cancer

(2015) Rishabh Kala et al.   BMC CANCER

Resveratrol exerts a biphasic effect on apolipoprotein M

(2015) Makoto Kurano et al.   BRITISH JOURNAL OF PHARMACOLOGY

SIRT1 Suppresses Doxorubicin-Induced Cardiotoxicity by Regulating the Oxidative Stress and p38MAPK Pathways

(2015) Yang Ruan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

DNA Methyltransferases Inhibitors from Natural Sources

(2015) Clemens Zwergel et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

SIRT1 activation rescues doxorubicin-induced loss of functional competence of human cardiac progenitor cells

(2015) Antonella De Angelis et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Resveratrol prevents doxorubicin-induced cardiotoxicity in H9c2 cells through the inhibition of endoplasmic reticulum stress and the activation of the Sirt1 pathway

(2015) YU LOU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Resveratrol protects against doxorubicin-induced cardiotoxicity in aged hearts through the SIRT1-USP7 axis

(2015) Thomas K. Sin et al.   JOURNAL OF PHYSIOLOGY-LONDON

SIRT1 Suppresses Human T-Cell Leukemia Virus Type 1 Transcription

(2015) Hei-Man Vincent Tang et al.   JOURNAL OF VIROLOGY

ERK5/HDAC5-mediated, resveratrol-, and pterostilbene-induced expression of MnSOD in human endothelial cells

(2015) Woting Gan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Nutritional immunology: function of natural killer cells and their modulation by resveratrol for cancer prevention and treatment

(2015) Christian Leischner et al.   Nutrition Journal

Resveratrol: A Focus on Several Neurodegenerative Diseases

(2015) Ester Tellone et al.   Oxidative Medicine and Cellular Longevity

Resveratrol Induced Premature Senescence Is Associated with DNA Damage Mediated SIRT1 and SIRT2 Down-Regulation

(2015) Mehtap Kilic Eren et al.   PLoS One

Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death

(2015) Natascia Guida et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

NAD+-dependent SIRT1 deactivation has a key role on ischemia–reperfusion-induced apoptosis

(2015) Arianna Cattelan et al.   VASCULAR PHARMACOLOGY

Genetic alterations of DNA methylation machinery in human diseases

(2015) Tewfik Hamidi et al.   Epigenomics

KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease

(2015) Tamara Maes et al.   Epigenomics

Resveratrol Targets in Inflammation

(2015) Hiroyasu Inoue et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Metformin and Resveratrol Inhibited High Glucose-Induced Metabolic Memory of Endothelial Senescence through SIRT1/p300/p53/p21 Pathway

(2015) Erli Zhang et al.   PLoS One

Resveratrol enhanced FOXO3 phosphorylation via synergetic activation of SIRT1 and PI3K/Akt signaling to improve the effects of exercise in elderly rat hearts

(2014) Chih-Hsueh Lin et al.   AGE

Involvement of TACE in colon inflammation: A novel mechanism of regulation via SIRT-1 activation

(2014) Manoranjan Sharma et al.   CYTOKINE

Acute Neuroinflammation Impairs Context Discrimination Memory and Disrupts Pattern Separation Processes in Hippocampus

(2014) J. Czerniawski et al.   JOURNAL OF NEUROSCIENCE

Modulating effect of SIRT1 activation induced by resveratrol on Foxo1-associated apoptotic signalling in senescent heart

(2014) Thomas K. Sin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Unknown

(2014) Bixi Jian et al.   MOLECULAR MEDICINE

Methylation and miRNA Effects of Resveratrol on Mammary Tumors vs. Normal Tissue

(2014) Wenyi Qin et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Spinal SIRT1 Activation Attenuates Neuropathic Pain in Mice

(2014) Haijun Shao et al.   PLoS One

Resveratrol regulates mitochondrial reactive oxygen species homeostasis through Sirt3 signaling pathway in human vascular endothelial cells

(2014) X Zhou et al.   Cell Death & Disease

DNA Methyltransferases: A Novel Target for Prevention and Therapy

(2014) Dharmalingam Subramaniam et al.   Frontiers in Oncology

Resveratrol Attenuates the Release of Inflammatory Cytokines from Human Bronchial Smooth Muscle Cells Exposed to Lipoteichoic Acid in Chronic Obstructive Pulmonary Disease

(2013) Jürgen Knobloch et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Resveratrol protects cardiomyocytes from oxidative stress through SIRT1 and mitochondrial biogenesis signaling pathways

(2013) Yong-guang Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The histone LSD1 demethylase in stemness and cancer transcription programs

(2013) Stefano Amente et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Neuroprotective effects of resveratrol on damages of mouse cortical neurons induced by β-amyloid through activation of SIRT1/Akt1 pathway

(2013) Jing Zhang et al.   BIOFACTORS

Lysine-specific histone demethylase LSD1 and the dynamic control of chromatin

(2013) Thomas Rudolph et al.   BIOLOGICAL CHEMISTRY

Resveratrol Improves Adipose Insulin Signaling and Reduces the Inflammatory Response in Adipose Tissue of Rhesus Monkeys on High-Fat, High-Sugar Diet

(2013) Yolanda Jimenez-Gomez et al.   Cell Metabolism

Novel Role of Silent Information Regulator 1 in Myocardial Ischemia

(2013) Yang Yang et al.   CIRCULATION

Medicinal Chemistry of the Epigenetic Diet and Caloric Restriction

(2013) S. Martin et al.   CURRENT MEDICINAL CHEMISTRY

Modulatory mechanisms controlling the NLRP3 inflammasome in inflammation: recent developments

(2013) Moritz Haneklaus et al.   CURRENT OPINION IN IMMUNOLOGY

Resveratrol delays Wallerian degeneration in a NAD+ and DBC1 dependent manner

(2013) Aldo Calliari et al.   EXPERIMENTAL NEUROLOGY

Sirt1 resists advanced glycation end products-induced expressions of fibronectin and TGF-β1 by activating the Nrf2/ARE pathway in glomerular mesangial cells

(2013) Kaipeng Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Resveratrol Inhibits Ionising Irradiation-Induced Inflammation in MSCs by Activating SIRT1 and Limiting NLRP-3 Inflammasome Activation

(2013) Yue Fu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sirtuin 1-mediated Effects of Exercise and Resveratrol on Mitochondrial Biogenesis

(2013) Keir J. Menzies et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol Improves Cardiomyopathy in Dystrophin-deficient Mice through SIRT1 Protein-mediated Modulation of p300 Protein

(2013) Atsushi Kuno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of DNA Methyltransferases in Breast Cancer Patients and to Analyze the Effect of Natural Compounds on DNA Methyltransferases and Associated Proteins

(2013) Sameer Mirza et al.   Journal of Breast Cancer

Resveratrol ameliorates subacute intestinal ischemia-reperfusion injury

(2013) WenPeng Dong et al.   JOURNAL OF SURGICAL RESEARCH

Sirt1 Promotes Axonogenesis by Deacetylation of Akt and Inactivation of GSK3

(2013) Xiao-hong Li et al.   MOLECULAR NEUROBIOLOGY

Curcumin as a regulator of epigenetic events

(2013) Marie-Hélène Teiten et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction

(2013) Lihong Shi et al.   NATURE MEDICINE

Epigenetic regulation of BDNF expression in the primary sensory neurons after peripheral nerve injury: Implications in the development of neuropathic pain

(2013) H. Uchida et al.   NEUROSCIENCE

Protective effect of SIRT1 on toxicity of microglial-derived factors induced by LPS to PC12 cells via the p53-caspase-3-dependent apoptotic pathway

(2013) Jieming Ye et al.   NEUROSCIENCE LETTERS

Resveratrol suppresses the STAT3 signaling pathway and inhibits proliferation of high glucose-exposed HepG2 cells partly through SIRT1

(2013) YONGGUANG LI et al.   ONCOLOGY REPORTS

Resveratrol Inhibits β-Amyloid-Induced Neuronal Apoptosis through Regulation of SIRT1-ROCK1 Signaling Pathway

(2013) Xiaowen Feng et al.   PLoS One

Correction: Resveratrol as a Pan-HDAC Inhibitor Alters the Acetylation Status of Jistone Proteins in Human-Derived Hepatoblastoma Cells

(2013) Sascha Venturelli et al.   PLoS One

Resveratrol Attenuates Diabetic Nephropathy via Modulating Angiogenesis

(2013) Donghai Wen et al.   PLoS One

Mitochondria in Vascular Health and Disease

(2012) Peter Dromparis et al.   Annual Review of Physiology

Activation of SIRT1 protects pancreatic β-cells against palmitate-induced dysfunction

(2012) Ling Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Sirtuin activators and inhibitors

(2012) José M. Villalba et al.   BIOFACTORS

Dietary Resveratrol Prevents Development of High-Grade Prostatic Intraepithelial Neoplastic Lesions: Involvement of SIRT1/S6K Axis

(2012) G. Li et al.   Cancer Prevention Research

Porphyromonas gingivalis lipopolysaccharide regulates interleukin (IL)-17 and IL-23 expression via SIRT1 modulation in human periodontal ligament cells

(2012) Yong-Duk Park et al.   CYTOKINE

Effects of resveratrol on longevity, cognitive ability and aging-related histological markers in the annual fish Nothobranchius guentheri

(2012) Xin Yu et al.   EXPERIMENTAL GERONTOLOGY

SDF-1 in myocardial repair

(2012) M S Penn et al.   GENE THERAPY

DNMT3B promoter polymorphisms and maternal risk of birth of a child with Down syndrome

(2012) Fabio Coppedè et al.   HUMAN REPRODUCTION

Resveratrol-mediated apoptosis of hodgkin lymphoma cells involves SIRT1 inhibition and FOXO3a hyperacetylation

(2012) Raffaele Frazzi et al.   INTERNATIONAL JOURNAL OF CANCER

Control of MicroRNA Expression as a New Way for Resveratrol To Deliver Its Beneficial Effects

(2012) Allan Lançon et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Resveratrol preconditioning increases methionine sulfoxide reductases A expression and enhances resistance of human neuroblastoma cells to neurotoxins

(2012) Peng-Fei Wu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Evaluation of Resveratrol, Green Tea Extract, Curcumin, Oxaloacetic Acid, and Medium-Chain Triglyceride Oil on Life Span of Genetically Heterogeneous Mice

(2012) R. Strong et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The effect of resveratrol on FoxO1 expression in kidneys of diabetic nephropathy rats

(2012) Lina Wu et al.   MOLECULAR BIOLOGY REPORTS

Unknown

(2012) Bixi Jian et al.   MOLECULAR MEDICINE

Epigenetic protein families: a new frontier for drug discovery

(2012) Cheryl H. Arrowsmith et al.   NATURE REVIEWS DRUG DISCOVERY

Acute Resveratrol Treatment Modulates Multiple Signaling Pathways in the Ischemic Brain

(2012) Jin A. Shin et al.   NEUROCHEMICAL RESEARCH

Review: Axon pathology in age-related neurodegenerative disorders

(2012) R. Adalbert et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

SIRT1, a class III histone deacetylase, regulates TNF-α-induced inflammation in human chondrocytes

(2012) M.-H. Moon et al.   OSTEOARTHRITIS AND CARTILAGE

Negative regulation of inflammation by SIRT1

(2012) Jun Xie et al.   PHARMACOLOGICAL RESEARCH

SIRT1 activating compounds reduce oxidative stress and prevent cell death in neuronal cells

(2012) Reas S. Khan et al.   Frontiers in Cellular Neuroscience

Emerging Epigenetic Targets and Therapies in Cancer Medicine

(2012) Relja Popovic et al.   Cancer Discovery

Resveratrol in cardiovascular health and disease

(2011) Goran Petrovski et al.   Annals of the New York Academy of Sciences

Anti-diabetic effects of resveratrol

(2011) Tomasz Szkudelski et al.   Annals of the New York Academy of Sciences

Resveratrol and life extension

(2011) Beamon Agarwal et al.   Annals of the New York Academy of Sciences

Resveratrol: a cardioprotective substance

(2011) Joseph M. Wu et al.   Annals of the New York Academy of Sciences

The Pathogenesis of Sepsis

(2011) Deborah J. Stearns-Kurosawa et al.   Annual Review of Pathology-Mechanisms of Disease

Global DNA methylation and risk of subclinical atherosclerosis in young adults: The Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study

(2011) Jan Bressler et al.   ATHEROSCLEROSIS

Influence of aging and hemorrhage injury on Sirt1 expression: Possible role of myc-Sirt1 regulation in mitochondrial function

(2011) Bixi Jian et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Targeting Androgen Receptor in Estrogen Receptor-Negative Breast Cancer

(2011) Min Ni et al.   CANCER CELL

Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53

(2011) C. Zhang et al.   CARDIOVASCULAR RESEARCH

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Epigenetic Events Associated with Breast Cancer and Their Prevention by Dietary Components Targeting the Epigenome

(2011) Shabana I. Khan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Cardiovascular Risk in Systemic Autoimmune Diseases: Epigenetic Mechanisms of Immune Regulatory Functions

(2011) Chary López-Pedrera et al.   Clinical & Developmental Immunology

Facioscapulohumeral muscular dystrophy

(2011) Jeffrey M. Statland et al.   CURRENT OPINION IN NEUROLOGY

Mitochondrial Protection by Resveratrol

(2011) Zoltan Ungvari et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Neurobiological aspects of Alzheimer's disease

(2011) Kanwaljit Chopra et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Airway smooth muscle and immunomodulation in acute exacerbations of airway disease

(2011) Cynthia J. Koziol-White et al.   IMMUNOLOGICAL REVIEWS

Genome-wide methylation profiling in Crohnʼs disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway

(2011) Elaine R. Nimmo et al.   INFLAMMATORY BOWEL DISEASES

Patients with a phenotype consistent with facioscapulohumeral muscular dystrophy display genetic and epigenetic heterogeneity

(2011) Sabrina Sacconi et al.   JOURNAL OF MEDICAL GENETICS

Involvement of interleukin-1 in lipopolysaccaride-induced microglial activation and learning and memory deficits

(2011) S. Tanaka et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Resveratrol up-regulates SIRT1 and inhibits cellular oxidative stress in the diabetic milieu: mechanistic insights

(2011) Jung-Mi Yun et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

State-dependent changes in the expression of DNA methyltransferases in mood disorder patients

(2011) Fumihiro Higuchi et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Unknown

(2011) Bixi Jian et al.   MOLECULAR MEDICINE

Protective effects of resveratrol through the up-regulation of SIRT1 expression in the mutant hSOD1-G93A-bearing motor neuron-like cell culture model of amyotrophic lateral sclerosis

(2011) Jing Wang et al.   NEUROSCIENCE LETTERS

Resveratrol protects against hyperglycemia-induced oxidative damage to mitochondria by activating SIRT1 in rat mesangial cells

(2011) Ying Xu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Epigenetic diet: impact on the epigenome and cancer

(2011) Tabitha M Hardy et al.   Epigenomics

Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors

(2010) Flora Chik et al.   CARCINOGENESIS

Structure and Function of Mammalian DNA Methyltransferases

(2010) Renata Zofia Jurkowska et al.   CHEMBIOCHEM

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

Resveratrol Potentiates Glucose-stimulated Insulin Secretion in INS-1E β-Cells and Human Islets through a SIRT1-dependent Mechanism

(2010) Laurène Vetterli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol Prevents Epigenetic Silencing of BRCA-1 by the Aromatic Hydrocarbon Receptor in Human Breast Cancer Cells

(2010) Andreas J. Papoutsis et al.   JOURNAL OF NUTRITION

DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models☆☆☆

(2010) Andrea Fuso et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

(2010) Richard A. Miller et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Novel Insights for Systemic Inflammation in Sepsis and Hemorrhage

(2010) Bolin Cai et al.   MEDIATORS OF INFLAMMATION

SIRT1, a histone deacetylase, regulates prion protein-induced neuronal cell death

(2010) Jae-Suk Seo et al.   NEUROBIOLOGY OF AGING

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy

(2010) M Matsuoka et al.   ONCOGENE

Histone demethylases in development and disease

(2010) Marianne Terndrup Pedersen et al.   TRENDS IN CELL BIOLOGY

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

(2010) E Morselli et al.   Cell Death & Disease

Resveratrol induces mitochondrial biogenesis in endothelial cells

(2009) Anna Csiszar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells

(2009) Zoltan Ungvari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Roles of the Akt/GSK-3 and Wnt Signaling Pathways in Schizophrenia and Antipsychotic Drug Action

(2009) Zachary Freyberg et al.   AMERICAN JOURNAL OF PSYCHIATRY

The role of reactive oxygen species in apoptosis of the diabetic kidney

(2009) F. A. D. T. G. Wagener et al.   APOPTOSIS

UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer

(2009) Wei Jin et al.   BREAST CANCER RESEARCH AND TREATMENT

FXR Acetylation Is Normally Dynamically Regulated by p300 and SIRT1 but Constitutively Elevated in Metabolic Disease States

(2009) Jongsook Kim Kemper et al.   Cell Metabolism

Histone Deacetylase Inhibition Activity and Molecular Docking of (E )-Resveratrol: Its Therapeutic Potential in Spinal Muscular Atrophy

(2009) Didem Dayangaç-Erden et al.   Chemical Biology & Drug Design

Central Administration of Resveratrol Improves Diet-Induced Diabetes

(2009) Giorgio Ramadori et al.   ENDOCRINOLOGY

Resveratrol inhibits proliferation and promotes apoptosis of osteosarcoma cells

(2009) Yan Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Sirtuin activators

(2009) Francisco J Alcaín et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway

(2009) Elizabeth D. Brookins Danz et al.   FREE RADICAL BIOLOGY AND MEDICINE

Resveratrol enhances p53 acetylation and apoptosis in prostate cancer by inhibiting MTA1/NuRD complex

(2009) Li Kai et al.   INTERNATIONAL JOURNAL OF CANCER

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Resveratrol (Trans-3,5,4'-trihydroxystilbene) Induces Silent Mating Type Information Regulation-1 and Down-Regulates Nuclear Transcription Factor- B Activation to Abrogate Dextran Sulfate Sodium-Induced Colitis

(2009) U. P. Singh et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1–uncoupling protein 2 pathway

(2009) D. Della-Morte et al.   NEUROSCIENCE

Molecular and Neurochemical Mechanisms in PD Pathogenesis

(2009) Irmgard Paris et al.   NEUROTOXICITY RESEARCH

Amyotrophic lateral sclerosis

(2009) Lokesh C Wijesekera et al.   Orphanet Journal of Rare Diseases

Cartilage homeostasis in health and rheumatic diseases

(2009) Mary B Goldring et al.   ARTHRITIS RESEARCH & THERAPY

Resveratrol alleviates alcoholic fatty liver in mice

(2008) Joanne M. Ajmo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations

(2008) Anna Csiszar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Reperfusion Injury After Hemorrhage

(2008) G D. Rushing et al.   ANNALS OF SURGERY

Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1–FoxO1 pathway

(2008) Chun-Juan Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Blocked Autophagy Sensitizes Resistant Carcinoma Cells to Radiation Therapy

(2008) A. Apel et al.   CANCER RESEARCH

Oxidative Stress as a Major Culprit in Kidney Disease in Diabetes

(2008) J. M. Forbes et al.   DIABETES

MsrA knockout mouse exhibits abnormal behavior and brain dopamine levels

(2008) Derek B. Oien et al.   FREE RADICAL BIOLOGY AND MEDICINE

Methionine sulfoxide reductase A protects dopaminergic cells from Parkinson's disease-related insults

(2008) Fang Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

SIRT1 Regulates Hepatocyte Lipid Metabolism through Activating AMP-activated Protein Kinase

(2008) Xiuyun Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cytokine network in asthma and chronic obstructive pulmonary disease

(2008) Peter J. Barnes   JOURNAL OF CLINICAL INVESTIGATION

Atrial Fibrosis: Mechanisms and Clinical Relevance in Atrial Fibrillation

(2008) Brett Burstein et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth

(2008) Ron Firestein et al.   PLoS One