Metformin and Resveratrol Inhibited High Glucose-Induced Metabolic Memory of Endothelial Senescence through SIRT1/p300/p53/p21 Pathway

Resveratrol supplementation: Where are we now and where should we go?

(2015) Marta G. Novelle et al.   AGEING RESEARCH REVIEWS

Pharmacologic Treatment of Type 2 Diabetes

(2015) Linda Tran et al.   ANNALS OF PHARMACOTHERAPY

Evaluating the Role of Epigenetic Histone Modifications in the Metabolic Memory of Type 1 Diabetes

(2014) Feng Miao et al.   DIABETES

Epigenetic mechanisms in diabetic complications and metabolic memory

(2014) Marpadga A. Reddy et al.   DIABETOLOGIA

Enhancing the Delivery of Resveratrol in Humans: If Low Bioavailability is the Problem, What is the Solution?

(2014) James Smoliga et al.   MOLECULES

p53 Acetylation: Regulation and Consequences

(2014) Sara Reed et al.   Cancers

Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1

(2013) Gnanapragasam Arunachalam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Molecular mechanism of action of metformin: old or new insights?

(2013) Graham Rena et al.   DIABETOLOGIA

High Glucose Induced Alteration of SIRTs in Endothelial Cells Causes Rapid Aging in a p300 and FOXO Regulated Pathway

(2013) Rokhsana Mortuza et al.   PLoS One

Aging and Atherosclerosis

(2012) Julie C. Wang et al.   CIRCULATION RESEARCH

Gene Silencing of the Mitochondrial Adaptor p66 Shc Suppresses Vascular Hyperglycemic Memory in Diabetes

(2012) Francesco Paneni et al.   CIRCULATION RESEARCH

Sirtuin 1-Mediated Cellular Metabolic Memory of High Glucose Via the LKB1/AMPK/ROS Pathway and Therapeutic Effects of Metformin

(2011) Z. Zheng et al.   DIABETES

The worldwide epidemiology of type 2 diabetes mellitus—present and future perspectives

(2011) Lei Chen et al.   Nature Reviews Endocrinology

Sirtuin1-p53, forkhead box O3a, p38 and post-infarct cardiac remodeling in the spontaneously diabetic Goto-Kakizaki rat

(2010) Erik Vahtola et al.   Cardiovascular Diabetology

Role of histone acetylation in the development of diabetic retinopathy and the metabolic memory phenomenon

(2010) Qing Zhong et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A review of endothelial dysfunction in diabetes: a focus on the contribution of a dysfunctional eNOS

(2010) Chris R. Triggle et al.   Journal of the American Society of Hypertension

Protective Role of SIRT1 in Diabetic Vascular Dysfunction

(2009) Masayuki Orimo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hyperglycemia Induces a Dynamic Cooperativity of Histone Methylase and Demethylase Enzymes Associated With Gene-Activating Epigenetic Marks That Coexist on the Lysine Tail

(2009) D. Brasacchio et al.   DIABETES

Forkhead class O transcription factor 3a activation and Sirtuin1 overexpression in the hypertrophied myocardium of the diabetic Goto-Kakizaki rat

(2009) Erik Vahtola et al.   JOURNAL OF HYPERTENSION

Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice

(2008) Rui-Hong Wang et al.   CANCER CELL

Vascular endothelial senescence: from mechanisms to pathophysiology

(2008) Jorge D. Erusalimsky   JOURNAL OF APPLIED PHYSIOLOGY