Discovery of potential antifungal triazoles: design, synthesis, biological evaluation, and preliminary antifungal mechanism exploration

Synthesis and bioactivity investigation of quinone-based dimeric cationic triazolium amphiphiles selective against resistant fungal and bacterial pathogens

(2017) Jaya P. Shrestha et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antibiotic tolerance facilitates the evolution of resistance

(2017) Irit Levin-Reisman et al.   SCIENCE

Design, synthesis and biological evaluation of amino organophosphorus imidazoles as a new type of potential antimicrobial agents

(2017) Wei-Wei Gao et al.   Science China-Chemistry

Design, synthesis and biological evaluation of novel Schiff base-bridged tetrahydroprotoberberine triazoles as a new type of potential antimicrobial agents

(2017) Jun-Rong Duan et al.   MedChemComm

Discovery of novel berberine imidazoles as safe antimicrobial agents by down regulating ROS generation

(2016) Si-Qi Wen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis and biological evaluation of 5-fluorouracil-derived benzimidazoles as novel type of potential antimicrobial agents

(2016) Xue-Jie Fang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Current Researches and Applications of Azole-BasedSupermolecules as Medicinal Agents

(2016) Yu Cheng et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Heterocyclic Naphthalimides as New Skeleton Structure of Compounds with Increasingly Expanding Relational Medicinal Applications

(2016) Huo-Hui Gong et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Azide-enolate 1,3-dipolar cycloaddition in the synthesis of novel triazole-based miconazole analogues as promising antifungal agents

(2016) Davir González-Calderón et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Microwave-assisted synthesis and antifungal activity of novel coumarin derivatives: Pyrano[3,2- c ]chromene-2,5-diones

(2016) Rong-Rong Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of berberine-benzimidazole hybrids as new type of potentially DNA-targeting antimicrobial agents

(2016) Ponmani Jeyakkumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of membrane active benzimidazole quinolones-based topoisomerase inhibitors as potential DNA-binding antimicrobial agents

(2016) Ling Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Multi-targeting exploration of new 2-aminothiazolyl quinolones: Synthesis, antimicrobial evaluation, interaction with DNA, combination with topoisomerase IV and penetrability into cells

(2016) Yu Cheng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Quinazolinone azolyl ethanols: potential lead antimicrobial agents with dual action modes targeting methicillin-resistantStaphylococcus aureusDNA

(2016) Xin-Mei Peng et al.   Future Medicinal Chemistry

Miconazole-loaded solid lipid nanoparticles: formulation and evaluation of a novel formula with high bioavailability and antifungal activity

(2016) Bader Aljaeid et al.   International Journal of Nanomedicine

Novel 3-Aminothiazolquinolones: Design, Synthesis, Bioactive Evaluation, SARs, and Preliminary Antibacterial Mechanism

(2016) Sheng-Feng Cui et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, biological evaluation and molecular docking of novel coumarin incorporated triazoles as antitubercular, antioxidant and antimicrobial agents

(2016) Mubarak H. Shaikh et al.   MEDICINAL CHEMISTRY RESEARCH

New Progress in Azole Compounds as Antimicrobial Agents

(2016) Hui-Zhen Zhang et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Antibacterial drug discovery in the resistance era

(2016) Eric D. Brown et al.   NATURE

Dual action antifungal small molecule modulates multidrug efflux and TOR signaling

(2016) Tanvi Shekhar-Guturja et al.   Nature Chemical Biology

Foretelling toxicity: FDA researchers work to predict risk of liver injury from drugs

(2016) Cassandra Willyard   NATURE MEDICINE

Coumarin-derived azolyl ethanols: synthesis, antimicrobial evaluation and preliminary action mechanism

(2016) Xin-Mei Peng et al.   Science China-Chemistry

Synthesis and biological evaluation of Schiff base-linked imidazolyl naphthalimides as novel potential anti-MRSA agents

(2016) Huo-Hui Gong et al.   MedChemComm

Design, synthesis, and biological evaluation of novel carbazole aminothiazoles as potential DNA-targeting antimicrobial agents

(2016) Dinesh Addla et al.   MedChemComm

Stimulation of superoxide production increases fungicidal action of miconazole against Candida albicans biofilms

(2016) Kaat De Cremer et al.   Scientific Reports

Comparison of theIn VitroActivities of Newer Triazoles and Established Antifungal Agents against Trichophyton rubrum

(2015) Shuwen Deng et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Design, Synthesis, and Antimicrobial Evaluation of Novel Quinolone Imidazoles and Interactions with MRSA DNA

(2015) Ling Zhang et al.   Chemical Biology & Drug Design

An Efficient Microwave-Assisted Suzuki Cross-Coupling on Coumarin Derivatives in Water and Evaluation of Antimicrobial Activity

(2015) Dongamanti Ashok et al.   LETTERS IN ORGANIC CHEMISTRY

Antimicrobial evaluation, QSAR and docking studies of amide-linked 1,4-disubstituted 1,2,3-bistriazoles

(2015) Kashmiri Lal et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis of novel sulfonamide azoles via C–N cleavage of sulfonamides by azole ring and relational antimicrobial study

(2015) Hui-Zhen Zhang et al.   NEW JOURNAL OF CHEMISTRY

Synthesis and biological evaluation of a new class of quinazolinoneazoles as potential antimicrobial agents and their interactions with calf thymus DNA and human serum albumin

(2015) Li-Ping Peng et al.   MedChemComm

Synthesis of tetrazole compounds as a novel type of potential antimicrobial agents and their synergistic effects with clinical drugs and interactions with calf thymus DNA

(2015) Ling-Ling Dai et al.   MedChemComm

Synthesis and bioactive evaluation of a novel series of coumarinazoles

(2014) Guri L.V. Damu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The synthesis and activities of novel mononuclear or dinuclear cyclen complexes bearing azole pendants as antibacterial and antifungal agents

(2014) Shuo Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of a class of quinolone triazoles as potential antimicrobial agents and their interactions with calf thymus DNA

(2013) Sheng-Feng Cui et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

1,2,3-Triazole-derived naphthalimides as a novel type of potential antimicrobial agents: Synthesis, antimicrobial activity, interaction with calf thymus DNA and human serum albumin

(2013) Jing-Song Lv et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Current Developments in the Syntheses of 1,2,4-Triazole Compounds

(2013) Hui-Zhen Zhang et al.   CURRENT ORGANIC CHEMISTRY

Current Developments of Coumarin Compounds in Medicinal Chemistry

(2013) Xin-Mei Peng et al.   CURRENT PHARMACEUTICAL DESIGN

Recent Developments in Azole Compounds as Antibacterial and Antifungal Agents

(2013) Xin-Mei Peng et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Design, synthesis and antimicrobial evaluation of novel benzimidazole type of Fluconazole analogues and their synergistic effects with Chloromycin, Norfloxacin and Fluconazole

(2013) Hui-Zhen Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of α-triazolyl chalcones as a new type of potential antimicrobial agents and their interaction with calf thymus DNA and human serum albumin

(2013) Ben-Tao Yin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry

(2013) Ling Zhang et al.   MEDICINAL RESEARCH REVIEWS

Antifungal agents commonly used in the superficial and mucosal candidiasis treatment: mode of action and resistance development

(2013) Małgorzata Bondaryk et al.   Postepy Dermatologii i Alergologii

A series of naphthalimide azoles: Design, synthesis and bioactive evaluation as potential antimicrobial agents

(2013) Guri L. V. Damu et al.   Science China-Chemistry

Berberine azoles as antimicrobial agents: synthesis, biological evaluation and their interactions with human serum albumin

(2013) Shao-Lin Zhang et al.   MedChemComm

Molecular Spectroscopy Evidence of Berberine Binding to DNA: Comparative Binding and Thermodynamic Profile of Intercalation

(2012) Xiao-Ling Li et al.   BIOMACROMOLECULES

Recent Researches in Triazole Compounds as Medicinal Drugs

(2012) C. -H. Zhou et al.   CURRENT MEDICINAL CHEMISTRY

Synthesis of novel fluconazoliums and their evaluation for antibacterial and antifungal activities

(2011) Yi-Yi Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation of new furanyl and thiophenyl azoles as antileishmanial agents

(2011) Vijay K. Marrapu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Molecular Spectroscopic Studies of Farrerol Interaction with Calf Thymus DNA

(2011) Guowen Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents

(2010) Yuan Shi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS