Design, synthesis and biological evaluation of novel Schiff base-bridged tetrahydroprotoberberine triazoles as a new type of potential antimicrobial agents

Recent Developments on 1,2,4-Triazole Nucleus in Anticancer Compounds: A Review

(2016) Ramandeep Kaur et al.   Anti-Cancer Agents in Medicinal Chemistry

Discovery of novel berberine imidazoles as safe antimicrobial agents by down regulating ROS generation

(2016) Si-Qi Wen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis and biological evaluation of 5-fluorouracil-derived benzimidazoles as novel type of potential antimicrobial agents

(2016) Xue-Jie Fang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Plant Natural Products Targeting Bacterial Virulence Factors

(2016) Laura Nunes Silva et al.   CHEMICAL REVIEWS

Current Researches and Applications of Azole-BasedSupermolecules as Medicinal Agents

(2016) Yu Cheng et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Kv1.5 Inhibitors for Treatment of Atrial Fibrillation: A Tradeoff between Selectivity and Non-selectivity

(2016) Xiaoke Guo et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Heterocyclic Naphthalimides as New Skeleton Structure of Compounds with Increasingly Expanding Relational Medicinal Applications

(2016) Huo-Hui Gong et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of berberine-benzimidazole hybrids as new type of potentially DNA-targeting antimicrobial agents

(2016) Ponmani Jeyakkumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Multi-targeting exploration of new 2-aminothiazolyl quinolones: Synthesis, antimicrobial evaluation, interaction with DNA, combination with topoisomerase IV and penetrability into cells

(2016) Yu Cheng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Quinazolinone azolyl ethanols: potential lead antimicrobial agents with dual action modes targeting methicillin-resistantStaphylococcus aureusDNA

(2016) Xin-Mei Peng et al.   Future Medicinal Chemistry

Design, Synthesis, and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective α1A-Adrenoceptor Antagonists

(2016) Diliang Guo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel 3-Aminothiazolquinolones: Design, Synthesis, Bioactive Evaluation, SARs, and Preliminary Antibacterial Mechanism

(2016) Sheng-Feng Cui et al.   JOURNAL OF MEDICINAL CHEMISTRY

New Progress in Azole Compounds as Antimicrobial Agents

(2016) Hui-Zhen Zhang et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Antibacterial drug discovery in the resistance era

(2016) Eric D. Brown et al.   NATURE

Coumarin-derived azolyl ethanols: synthesis, antimicrobial evaluation and preliminary action mechanism

(2016) Xin-Mei Peng et al.   Science China-Chemistry

Natural Products as a Source for Novel Antibiotics

(2016) Mark G. Moloney   TRENDS IN PHARMACOLOGICAL SCIENCES

Synthesis and biological evaluation of Schiff base-linked imidazolyl naphthalimides as novel potential anti-MRSA agents

(2016) Huo-Hui Gong et al.   MedChemComm

Design, synthesis, and biological evaluation of novel carbazole aminothiazoles as potential DNA-targeting antimicrobial agents

(2016) Dinesh Addla et al.   MedChemComm

A comparative binding mechanism between human serum albumin and α-1-acid glycoprotein with corilagin: biophysical and computational approach

(2016) Daniel Pushparaju Yeggoni et al.   RSC Advances

Design, Synthesis, and Antimicrobial Evaluation of Novel Quinolone Imidazoles and Interactions with MRSA DNA

(2015) Ling Zhang et al.   Chemical Biology & Drug Design

Current knowledge and pharmacological profile of berberine: An update

(2015) Anil Kumar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Azole antifungals: 35 years of invasive fungal infection management

(2015) David Allen et al.   Expert Review of Anti-Infective Therapy

Cytotoxicity and DNA interaction of brucine and strychnine—Two alkaloids of semen strychni

(2015) Fei Liu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Membrane Active Small Molecules Show Selective Broad Spectrum Antibacterial Activity with No Detectable Resistance and Eradicate Biofilms

(2015) Jiaul Hoque et al.   JOURNAL OF MEDICINAL CHEMISTRY

Multidrug evolutionary strategies to reverse antibiotic resistance

(2015) M. Baym et al.   SCIENCE

Design, synthesis, and antibacterial evaluation of novel azolylthioether quinolones as MRSA DNA intercalators

(2015) Ling Zhang et al.   MedChemComm

Synthesis and biological evaluation of a new class of quinazolinoneazoles as potential antimicrobial agents and their interactions with calf thymus DNA and human serum albumin

(2015) Li-Ping Peng et al.   MedChemComm

Synthesis of tetrazole compounds as a novel type of potential antimicrobial agents and their synergistic effects with clinical drugs and interactions with calf thymus DNA

(2015) Ling-Ling Dai et al.   MedChemComm

Triaryl-Substituted Schiff Bases Are High-Affinity Subtype-Selective Ligands for the Estrogen Receptor

(2014) Zong-Quan Liao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Structure–Activity Relationship Studies of Novel Fused Heterocycles-Linked Triazoles with Good Activity and Water Solubility

(2014) Xufeng Cao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Insight into the Binding Mechanism of Imipenem to Human Serum Albumin by Spectroscopic and Computational Approaches

(2014) Md Tabish Rehman et al.   MOLECULAR PHARMACEUTICS

Facile synthesis of tetrahydroprotoberberine and protoberberine alkaloids from protopines and study on their antibacterial activities

(2014) Pi Cheng et al.   NATURAL PRODUCT RESEARCH

Kinesin Spindle Protein Inhibitors with Diaryl Amine Scaffolds: Crystal Packing Analysis for Improved Aqueous Solubility

(2014) Tomoki Takeuchi et al.   ACS Medicinal Chemistry Letters

Synthesis and bioactive evaluation of novel hybrids of metronidazole and berberine as new type of antimicrobial agents and their transportation behavior by human serum albumin

(2013) Ling Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Current Developments in the Syntheses of 1,2,4-Triazole Compounds

(2013) Hui-Zhen Zhang et al.   CURRENT ORGANIC CHEMISTRY

Current Developments of Coumarin Compounds in Medicinal Chemistry

(2013) Xin-Mei Peng et al.   CURRENT PHARMACEUTICAL DESIGN

Recent Developments in Azole Compounds as Antibacterial and Antifungal Agents

(2013) Xin-Mei Peng et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Synthesis and biological evaluation of α-triazolyl chalcones as a new type of potential antimicrobial agents and their interaction with calf thymus DNA and human serum albumin

(2013) Ben-Tao Yin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry

(2013) Ling Zhang et al.   MEDICINAL RESEARCH REVIEWS

Berberine azoles as antimicrobial agents: synthesis, biological evaluation and their interactions with human serum albumin

(2013) Shao-Lin Zhang et al.   MedChemComm

Berberine: New perspectives for old remedies

(2012) Micol Tillhon et al.   BIOCHEMICAL PHARMACOLOGY

Chemical and microbial semi-synthesis of tetrahydroprotoberberines as inhibitors on tissue factor procoagulant activity

(2012) Hai-Xia Ge et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Novel berberine triazoles: Synthesis, antimicrobial evaluation and competitive interactions with metal ions to Human Serum Albumin

(2012) Shao-Lin Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and anticancer activity of a novel series of 9-O-substituted berberine derivatives: A lipophilic substitute role

(2012) Chih-Yu Lo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Recent Researches in Triazole Compounds as Medicinal Drugs

(2012) C. -H. Zhou et al.   CURRENT MEDICINAL CHEMISTRY

Spectroscopic Investigation on the Interaction of Pyrimidine Derivative, 2-Amino-6-hydroxy-4-(3,4-dimethoxyphenyl)-pyrimidine-5-carbonitrile with Human Serum Albumin: Mechanistic and Conformational Study

(2011) Vishwas D. Suryawanshi et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Molecular Spectroscopic Studies of Farrerol Interaction with Calf Thymus DNA

(2011) Guowen Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Improvement in Aqueous Solubility in Small Molecule Drug Discovery Programs by Disruption of Molecular Planarity and Symmetry

(2011) Minoru Ishikawa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Impact of Arsenic/Phosphorus Substitution on the Intrinsic Conformational Properties of the Phosphodiester Backbone of DNA Investigated Using ab Initio Quantum Mechanical Calculations

(2011) Elizabeth J. Denning et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Berberine derivatives, with substituted amino groups linked at the 9-position, as inhibitors of acetylcholinesterase/butyrylcholinesterase

(2010) Ling Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Investigation of the Interaction between Berberine and Human Serum Albumin

(2009) Yan-Jun Hu et al.   BIOMACROMOLECULES