The GABAergic Hypothesis for Cognitive Disabilities in Down Syndrome

Long-Term Outcomes of Developmental Exposure to Fluoxetine: A Review of the Animal Literature

(2017) Veronika Kiryanova et al.   DEVELOPMENTAL NEUROSCIENCE

Memantine Normalizes Several Phenotypic Features in the Ts65Dn Mouse Model of Down Syndrome

(2017) Noemí Rueda et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer's Disease and Down Syndrome Rodent Models Exhibit Audiogenic Seizures

(2017) Cara J. Westmark et al.   JOURNAL OF ALZHEIMERS DISEASE

Infantile spasms in down syndrome: Rescue by knockdown of the GIRK2 channel

(2016) Krutika Joshi et al.   ANNALS OF NEUROLOGY

GABAergic hyperinnervation of dentate granule cells in the Ts65Dn mouse model of down syndrome: Exploring the role ofApp

(2016) Fatemeh S. Mojabi et al.   HIPPOCAMPUS

Pharmacotherapy in Down's syndrome: which way forward?

(2016) Fabian Fernandez et al.   LANCET NEUROLOGY

Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial

(2016) Rafael de la Torre et al.   LANCET NEUROLOGY

Mouse models of Down syndrome: gene content and consequences

(2016) Meenal Gupta et al.   MAMMALIAN GENOME

Differential dopaminergic regulation of inwardly rectifying potassium channel mediated subthreshold dynamics in striatal medium spiny neurons

(2016) Bo Zhao et al.   NEUROPHARMACOLOGY

Prevalence of Obstructive Sleep Apnea in Children with Down Syndrome

(2016) Mieke Maris et al.   SLEEP

Relationship between obstructive sleep apnea cardiac complications and sleepiness in children with Down syndrome

(2016) Sofia Konstantinopoulou et al.   SLEEP MEDICINE

Implications of GABAergic Neurotransmission in Alzheimer’s Disease

(2016) Yanfang Li et al.   Frontiers in Aging Neuroscience

Prevalence of Obstructive Sleep Apnea in Children with Down Syndrome

(2016) Mieke Maris et al.   SLEEP

Prenatal exposure to selective serotonin reuptake inhibitors (SSRI) increases aggression and modulates maternal behavior in offspring mice

(2015) Natali Svirsky et al.   DEVELOPMENTAL PSYCHOBIOLOGY

Deletion of GIRK2 Subunit of GIRK Channels Alters the 5-HT1AReceptor-Mediated Signaling and Results in a Depression-Resistant Behavior

(2015) Nerea Llamosas et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Multiple Forms of Endocannabinoid and Endovanilloid Signaling Regulate the Tonic Control of GABA Release

(2015) S.-H. Lee et al.   JOURNAL OF NEUROSCIENCE

Bumetanide for the treatment of seizures in newborn babies with hypoxic ischaemic encephalopathy (NEMO): an open-label, dose finding, and feasibility phase 1/2 trial

(2015) Ronit M Pressler et al.   LANCET NEUROLOGY

Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Down syndrome

(2015) Gabriele Deidda et al.   NATURE MEDICINE

Early environmental therapy rescues brain development in a mouse model of Down syndrome

(2015) Tatjana Begenisic et al.   NEUROBIOLOGY OF DISEASE

Sleep in Children with Neurodevelopmental Disabilities

(2015) Marco Angriman et al.   NEUROPEDIATRICS

Prevalence of epilepsy among people with intellectual disabilities: A systematic review

(2015) Janet Robertson et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Control of cortical neuronal migration by glutamate and GABA

(2015) Heiko J. Luhmann et al.   Frontiers in Cellular Neuroscience

Specific SSRIs and birth defects: bayesian analysis to interpret new data in the context of previous reports

(2015) Jennita Reefhuis et al.   BMJ-British Medical Journal

Pharmacological correction of excitation/inhibition imbalance in Down syndrome mouse models

(2015) Benoit Souchet et al.   Frontiers in Behavioral Neuroscience

Principal Component Analysis of the Effects of Environmental Enrichment and (-)-epigallocatechin-3-gallate on Age-Associated Learning Deficits in a Mouse Model of Down Syndrome

(2015) Silvina Catuara-Solarz et al.   Frontiers in Behavioral Neuroscience

Specific SSRIs and birth defects: bayesian analysis to interpret new data in the context of previous reports

(2015) Jennita Reefhuis et al.   BMJ-British Medical Journal

Early-life serotonin dysregulation affects the migration and positioning of cortical interneuron subtypes

(2015) S Frazer et al.   Translational Psychiatry

Involvement of Potassium and Cation Channels in Hippocampal Abnormalities of Embryonic Ts65Dn and Tc1 Trisomic Mice

(2015) Shani Stern et al.   EBioMedicine

Down Syndrome Cognitive Phenotypes Modeled in Mice Trisomic for All HSA 21 Homologues

(2015) Pavel V. Belichenko et al.   PLoS One

Pharmacological Characterization of 5-HT1A Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons

(2015) Alberto Montalbano et al.   PLoS One

The Glutamatergic Hypothesis for Down Syndrome: The Potential Use of N-Methyl-D-Aspartate Receptor Antagonists to Enhance Cognition and Decelerate Neurodegeneration

(2014) Alberto Costa   CNS & Neurological Disorders-Drug Targets

A Critical Evaluation of the Gamma-Hydroxybutyrate (GHB) Model of Absence Seizures

(2014) Marcello Venzi et al.   CNS Neuroscience & Therapeutics

Depolarizing GABA and Developmental Epilepsies

(2014) Roustem Khazipov et al.   CNS Neuroscience & Therapeutics

Lineage origins of GABAergic versus glutamatergic neurons in the neocortex

(2014) Oscar Marín et al.   CURRENT OPINION IN NEUROBIOLOGY

Long-term consequences of neonatal fluoxetine exposure in adult rats

(2014) Meng-Ching Ko et al.   Developmental Neurobiology

GABAAreceptors and plasticity of inhibitory neurotransmission in the central nervous system

(2014) Jean-Marc Fritschy et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The Developmental Switch in GABA Polarity Is Delayed in Fragile X Mice

(2014) Q. He et al.   JOURNAL OF NEUROSCIENCE

5-Hydroxytryptamine1Areceptor-activation hyperpolarizes pyramidal cells and suppresses hippocampal gamma oscillations via Kir3 channel activation

(2014) April Johnston et al.   JOURNAL OF PHYSIOLOGY-LONDON

Engineering a memory with LTD and LTP

(2014) Sadegh Nabavi et al.   NATURE

Early depolarizing GABA controls critical-period plasticity in the rat visual cortex

(2014) Gabriele Deidda et al.   NATURE NEUROSCIENCE

Cation-chloride cotransporters in neuronal development, plasticity and disease

(2014) Kai Kaila et al.   NATURE REVIEWS NEUROSCIENCE

Maternal choline supplementation improves spatial mapping and increases basal forebrain cholinergic neuron number and size in aged Ts65Dn mice

(2014) Jessica A. Ash et al.   NEUROBIOLOGY OF DISEASE

Altered Distribution of Hippocampal Interneurons in the Murine Down Syndrome Model Ts65Dn

(2014) Samuel Hernández-González et al.   NEUROCHEMICAL RESEARCH

Phasic Dopamine Release Drives Rapid Activation of Striatal D2-Receptors

(2014) Pamela F. Marcott et al.   NEURON

In vivo1H MRS study in microlitre voxels in the hippocampus of a mouse model of Down syndrome at 11.7 T

(2014) Mathieu D. Santin et al.   NMR IN BIOMEDICINE

Amino acid metabolic processes in the temporal lobes assessed by proton magnetic resonance spectroscopy (1Η MRS) in children with Down syndrome

(2014) Joanna Śmigielska-Kuzia et al.   Pharmacological Reports

Overexpression of Dyrk1A Is Implicated in Several Cognitive, Electrophysiological and Neuromorphological Alterations Found in a Mouse Model of Down Syndrome

(2014) Susana García-Cerro et al.   PLoS One

Monoacylglycerol Lipase Inhibitor JZL184 Improves Behavior and Neural Properties in Ts65Dn Mice, a Model of Down Syndrome

(2014) Larisa V. Lysenko et al.   PLoS One

Modulation of GABAergic transmission in development and neurodevelopmental disorders: investigating physiology and pathology to gain therapeutic perspectives

(2014) Gabriele Deidda et al.   Frontiers in Cellular Neuroscience

Regulation of adult neurogenesis by GABAergic transmission: signaling beyond GABAA-receptors

(2014) Marta Pallotto et al.   Frontiers in Cellular Neuroscience

Pharmacological approaches to improving cognitive function in Down syndrome: current status and considerations

(2014) Katheleen Gardiner   Drug Design Development and Therapy

GABAergic Signaling as Therapeutic Target for Autism Spectrum Disorders

(2014) Giada Cellot et al.   Frontiers in Pediatrics

GHB receptor targets in the CNS: Focus on high-affinity binding sites

(2013) Tina Bay et al.   BIOCHEMICAL PHARMACOLOGY

Prenatal pharmacotherapy rescues brain development in a Down’s syndrome mouse model

(2013) Sandra Guidi et al.   BRAIN

Short-term treatment with the GABAAreceptor antagonist pentylenetetrazole produces a sustained pro-cognitive benefit in a mouse model of Down's syndrome

(2013) D Colas et al.   BRITISH JOURNAL OF PHARMACOLOGY

GABA actions and ionic plasticity in epilepsy

(2013) Kai Kaila et al.   CURRENT OPINION IN NEUROBIOLOGY

Neuronal carbonic anhydrase VII provides GABAergic excitatory drive to exacerbate febrile seizures

(2013) Eva Ruusuvuori et al.   EMBO JOURNAL

Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21

(2013) Youssef Hibaoui et al.   EMBO Molecular Medicine

Multiplex Genetic Fate Mapping Reveals a Novel Route of Neocortical Neurogenesis, Which Is Altered in the Ts65Dn Mouse Model of Down Syndrome

(2013) W. A. Tyler et al.   JOURNAL OF NEUROSCIENCE

Reducing GABAA  5 Receptor-Mediated Inhibition Rescues Functional and Neuromorphological Deficits in a Mouse Model of Down Syndrome

(2013) C. Martinez-Cue et al.   JOURNAL OF NEUROSCIENCE

Chronic melatonin treatment rescues electrophysiological and neuromorphological deficits in a mouse model of Down syndrome

(2013) Andrea Corrales et al.   JOURNAL OF PINEAL RESEARCH

Focal uncaging of GABA reveals a temporally defined role for GABAergic inhibition during appetitive associative olfactory conditioning in honeybees

(2013) D. Raccuglia et al.   LEARNING & MEMORY

Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans

(2013) Rafael De la Torre et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome

(2013) Ramon Velazquez et al.   NEUROBIOLOGY OF DISEASE

Fluoxetine in adulthood normalizes GABA release and rescues hippocampal synaptic plasticity and spatial memory in a mouse model of Down Syndrome

(2013) Tatjana Begenisic et al.   NEUROBIOLOGY OF DISEASE

GABAergic Interneurons Shape the Functional Maturation of the Cortex

(2013) Corentin Le Magueresse et al.   NEURON

GluN2B Antagonism Affects Interneurons and Leads to Immediate and Persistent Changes in Synaptic Plasticity, Oscillations and Behavior

(2013) Jesse E Hanson et al.   NEUROPSYCHOPHARMACOLOGY

Pharmacotherapy with Fluoxetine Restores Functional Connectivity from the Dentate Gyrus to Field CA3 in the Ts65Dn Mouse Model of Down Syndrome

(2013) Fiorenza Stagni et al.   PLoS One

Spatial Memory and Long-Term Object Recognition Are Impaired by Circadian Arrhythmia and Restored by the GABAAAntagonist Pentylenetetrazole

(2013) Norman F. Ruby et al.   PLoS One

Deficits in human trisomy 21 iPSCs and neurons

(2013) J. P. Weick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurodevelopmental and psychiatric issues in Down’s syndrome

(2013) Stefano Vicari et al.   PSYCHIATRIC GENETICS

Hedgehog Agonist Therapy Corrects Structural and Cognitive Deficits in a Down Syndrome Mouse Model

(2013) I. Das et al.   Science Translational Medicine

Emerging neurotrophic role of GABAB receptors in neuronal circuit development

(2013) Jean-Luc Gaiarsa et al.   Frontiers in Cellular Neuroscience

Fluoxetine impairs GABAergic signaling in hippocampal slices from neonatal rats

(2013) Maddalena D. Caiati et al.   Frontiers in Cellular Neuroscience

Functional role of ambient GABA in refining neuronal circuits early in postnatal development

(2013) Giada Cellot et al.   Frontiers in Neural Circuits

Role of tonic GABAergic currents during pre- and early postnatal rodent development

(2013) Werner Kilb et al.   Frontiers in Neural Circuits

Role of dopamine D2 receptors in plasticity of stress-induced addictive behaviours

(2013) Hye-ri Sim et al.   Nature Communications

Non-hyperpolarizing GABAB receptor activation regulates neuronal migration and neurite growth and specification by cAMP/LKB1

(2013) Guillaume Bony et al.   Nature Communications

Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down’s syndrome

(2013) Marianna Szemes et al.   Molecular Brain

Critical-Period Plasticity in the Visual Cortex

(2012) Christiaan N. Levelt et al.   Annual Review of Neuroscience

Early Pharmacotherapy with Fluoxetine Rescues Dendritic Pathology in the Ts65Dn Mouse Model of Down Syndrome

(2012) Sandra Guidi et al.   BRAIN PATHOLOGY

Increased excitability and altered action potential waveform in cerebellar granule neurons of the Ts65Dn mouse model of Down syndrome

(2012) Maria M. Usowicz et al.   BRAIN RESEARCH

Developmentally altered inhibition in Ts65Dn, a mouse model of Down syndrome

(2012) Ananya Mitra et al.   BRAIN RESEARCH

Lithium rescues synaptic plasticity and memory in Down syndrome mice

(2012) Andrea Contestabile et al.   JOURNAL OF CLINICAL INVESTIGATION

Direct Alteration of a Specific Inhibitory Circuit of the Hippocampus by Antidepressants

(2012) P. Mendez et al.   JOURNAL OF NEUROSCIENCE

GABA Is Depolarizing in Hippocampal Dentate Granule Cells of the Adolescent and Adult Rats

(2012) P.-H. Chiang et al.   JOURNAL OF NEUROSCIENCE

Deficits in Cognition and Synaptic Plasticity in a Mouse Model of Down Syndrome Ameliorated by GABAB Receptor Antagonists

(2012) A. M. Kleschevnikov et al.   JOURNAL OF NEUROSCIENCE

Melatonin Modulates the GABAergic Response in Cultured Rat Hippocampal Neurons

(2012) Xin-Ping Cheng et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Memantine for dementia in adults older than 40 years with Down's syndrome (MEADOWS): a randomised, double-blind, placebo-controlled trial

(2012) Marisa Hanney et al.   LANCET

Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision

(2012) Juan Song et al.   NATURE

Regulation of neuronal GABAB receptor functions by subunit composition

(2012) Martin Gassmann et al.   NATURE REVIEWS NEUROSCIENCE

Down syndrome: the brain in trisomic mode

(2012) Mara Dierssen   NATURE REVIEWS NEUROSCIENCE

Intracellular chloride concentration influences the GABAA receptor subunit composition

(2012) Francesca Succol et al.   Nature Communications

Mouse Models of Down Syndrome as a Tool to Unravel the Causes of Mental Disabilities

(2012) Noemí Rueda et al.   NEURAL PLASTICITY

Antagonism of NMDA receptors as a potential treatment for Down syndrome: a pilot randomized controlled trial

(2012) R Boada et al.   Translational Psychiatry

Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome

(2011) Tyler K. Best et al.   EXPERIMENTAL NEUROLOGY

Activation of metabotropic GABA receptors increases the energy barrier for vesicle fusion

(2011) B. R. Rost et al.   JOURNAL OF CELL SCIENCE

(–)-Epigallocatechin-3-O-Gallate Augments Pentobarbital-Induced Sleeping Behaviors Through Cl− Channel Activation

(2011) Kwang-Soon Park et al.   JOURNAL OF MEDICINAL FOOD

Implications for treatment: GABAA receptors in aging, Down syndrome and Alzheimer’s disease

(2011) Robert A. Rissman et al.   JOURNAL OF NEUROCHEMISTRY

GABAB Receptor Modulation of Voltage-Sensitive Calcium Channels in Spines and Dendrites

(2011) J. R. Chalifoux et al.   JOURNAL OF NEUROSCIENCE

Specific targeting of the GABA-A receptor α5 subtype by a selective inverse agonist restores cognitive deficits in Down syndrome mice

(2011) J Braudeau et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Exaggerated NMDA mediated LTD in a mouse model of Down syndrome and pharmacological rescuing by memantine

(2011) J. J. Scott-McKean et al.   LEARNING & MEMORY

Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling down syndrome

(2011) Arnaud Duchon et al.   MAMMALIAN GENOME

Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes

(2011) Uwe Rudolph et al.   NATURE REVIEWS DRUG DISCOVERY

Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome

(2011) Alexander M. Kleschevnikov et al.   NEUROBIOLOGY OF DISEASE

Altered expression of neuropeptides in the primary somatosensory cortex of the Down syndrome model Ts65Dn

(2011) Samuel Hernández et al.   NEUROPEPTIDES

The GABA system in anxiety and depression and its therapeutic potential

(2011) Hanns Möhler   NEUROPHARMACOLOGY

The contribution of GABAergic dysfunction to neurodevelopmental disorders

(2011) Kartik Ramamoorthi et al.   TRENDS IN MOLECULAR MEDICINE

Environmental enrichment decreases GABAergic inhibition and improves cognitive abilities, synaptic plasticity, and visual functions in a mouse model of Down syndrome

(2011) Tatjana Begenisic et al.   Frontiers in Cellular Neuroscience

Perinatal choline supplementation improves cognitive functioning and emotion regulation in the Ts65Dn mouse model of Down syndrome.

(2010) Jisook Moon et al.   BEHAVIORAL NEUROSCIENCE

Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome

(2010) Jason Lockrow et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice

(2010) Tao Yu et al.   BRAIN RESEARCH

Evidence for oligomerization between GABAB receptors and GIRK channels containing the GIRK1 and GIRK3 subunits

(2010) Francisco Ciruela et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Methylation profile of TP53 regulatory pathway and mtDNA alterations in breast cancer patients lacking TP53 mutations

(2010) Zeinab Barekati et al.   HUMAN MOLECULAR GENETICS

Circadian Locomotor Rhythms Are Normal in Ts65Dn “Down Syndrome” Mice and Unaffected by Pentylenetetrazole

(2010) Norman F. Ruby et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Alteration of inhibitory circuits in the somatosensory cortex of Ts65Dn mice, a model for Down’s syndrome

(2010) D. Pérez-Cremades et al.   JOURNAL OF NEURAL TRANSMISSION

Electrophysiological Effects of Melatonin on Mouse Per1 and non-Per1 Suprachiasmatic Nuclei Neurones In Vitro

(2010) F. F. Scott et al.   JOURNAL OF NEUROENDOCRINOLOGY

Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome

(2010) P. Bianchi et al.   JOURNAL OF NEUROSCIENCE

Genetically encoded Cl-Sensor as a tool for monitoring of Cl-dependent processes in small neuronal compartments

(2010) Tatyana Waseem et al.   JOURNAL OF NEUROSCIENCE METHODS

The K+-Cl−cotransporter KCC2 promotes GABAergic excitation in the mature rat hippocampus

(2010) Tero Viitanen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Cognitive deficits and associated neurological complications in individuals with Down's syndrome

(2010) Ira T Lott et al.   LANCET NEUROLOGY

Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome

(2010) Lina Chakrabarti et al.   NATURE NEUROSCIENCE

Neuronal arithmetic

(2010) R. Angus Silver   NATURE REVIEWS NEUROSCIENCE

Dopamine D1-like receptor activation depolarizes medium spiny neurons of the mouse nucleus accumbens by inhibiting inwardly rectifying K+ currents through a cAMP-dependent protein kinase A-independent mechanism

(2010) M.V. Podda et al.   NEUROSCIENCE

Lithium Restores Neurogenesis in the Subventricular Zone of the Ts65Dn Mouse, a Model for Down Syndrome

(2009) Patrizia Bianchi et al.   BRAIN PATHOLOGY

Meiotic behavior of aneuploid chromatin in mouse models of Down syndrome

(2009) Laura G. Reinholdt et al.   CHROMOSOMA

A Critical Period in Cortical Interneuron Neurogenesis in Down Syndrome Revealed by Human Neural Progenitor Cells

(2009) Anita Bhattacharyya et al.   DEVELOPMENTAL NEUROSCIENCE

GABAB Receptor Activation Triggers BDNF Release and Promotes the Maturation of GABAergic Synapses

(2009) H. Fiorentino et al.   JOURNAL OF NEUROSCIENCE

Endocannabinoid-Dependent Homeostatic Regulation of Inhibitory Synapses by Miniature Excitatory Synaptic Activities

(2009) S.-y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Distinct Roles of GABAA and GABAB Receptors in Balancing and Terminating Persistent Cortical Activity

(2009) E. O. Mann et al.   JOURNAL OF NEUROSCIENCE

The "Down Syndrome Critical Region" Is Sufficient in the Mouse Model to Confer Behavioral, Neurophysiological, and Synaptic Phenotypes Characteristic of Down Syndrome

(2009) N. P. Belichenko et al.   JOURNAL OF NEUROSCIENCE

Defining the role of GABA in cortical development

(2009) Doris D. Wang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Control of hippocampal gamma oscillation frequency by tonic inhibition and excitation of interneurons

(2009) Edward O Mann et al.   NATURE NEUROSCIENCE

Infantile Spasms and Down Syndrome: A New Animal Model

(2009) Miguel A Cortez et al.   PEDIATRIC RESEARCH

Function and modulation of δ-containing GABAA receptors

(2009) Nadezhda N. Zheleznova et al.   PSYCHONEUROENDOCRINOLOGY

Molecular basis of pharmacotherapies for cognition in Down syndrome

(2009) Katheleen J. Gardiner   TRENDS IN PHARMACOLOGICAL SCIENCES

Reduced cell number in the neocortical part of the human fetal brain in Down syndrome

(2008) Karen Bonde Larsen et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Sleep problems in a Down syndrome population

(2008) M Carter et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Cell Cycle Elongation Impairs Proliferation of Cerebellar Granule Cell Precursors in the Ts65Dn Mouse, an Animal Model for Down Syndrome

(2008) Andrea Contestabile et al.   BRAIN PATHOLOGY

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

Behavioral characterization of mice lacking GIRK/Kir3 channel subunits

(2008) M. Pravetoni et al.   GENES BRAIN AND BEHAVIOR

Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of down syndrome

(2008) Pavel V. Belichenko et al.   JOURNAL OF COMPARATIVE NEUROLOGY

GABAergic Depolarization of the Axon Initial Segment in Cortical Principal Neurons Is Caused by the Na-K-2Cl Cotransporter NKCC1

(2008) S. Khirug et al.   JOURNAL OF NEUROSCIENCE

Excitatory Actions of GABA in the Suprachiasmatic Nucleus

(2008) H. J. Choi et al.   JOURNAL OF NEUROSCIENCE

Long-term potentiation-like facilitation through GABAA receptor blockade in the mouse dentate gyrus in vivo

(2008) Shogo Matsuyama et al.   NEUROREPORT

Chronic pentylenetetrazole but not donepezil treatment rescues spatial cognition in Ts65Dn mice, a model for Down syndrome

(2008) N. Rueda et al.   NEUROSCIENCE LETTERS

International Union of Pharmacology. LXX. Subtypes of  -Aminobutyric AcidA Receptors: Classification on the Basis of Subunit Composition, Pharmacology, and Function. Update

(2008) R. W. Olsen et al.   PHARMACOLOGICAL REVIEWS

Hippocampal-dependent learning requires a functional circadian system

(2008) N. F. Ruby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RO4938581, a novel cognitive enhancer acting at GABAA α5 subunit-containing receptors

(2008) Theresa M. Ballard et al.   PSYCHOPHARMACOLOGY

The Antidepressant Fluoxetine Restores Plasticity in the Adult Visual Cortex

(2008) J. F. M. Vetencourt et al.   SCIENCE

Sleep and EEG features in genetic models of Down syndrome

(2007) Damien Colas et al.   NEUROBIOLOGY OF DISEASE