Hedgehog Agonist Therapy Corrects Structural and Cognitive Deficits in a Down Syndrome Mouse Model

Reducing GABAA  5 Receptor-Mediated Inhibition Rescues Functional and Neuromorphological Deficits in a Mouse Model of Down Syndrome

(2013) C. Martinez-Cue et al.   JOURNAL OF NEUROSCIENCE

Increased excitability and altered action potential waveform in cerebellar granule neurons of the Ts65Dn mouse model of Down syndrome

(2012) Maria M. Usowicz et al.   BRAIN RESEARCH

Metastatic basal cell carcinoma in the era of hedgehog signaling pathway inhibitors

(2012) Glen J. Weiss et al.   CANCER

Cognitive and pharmacological insights from the Ts65Dn mouse model of Down syndrome

(2012) Aarti Ruparelia et al.   CURRENT OPINION IN NEUROBIOLOGY

Deficits in Cognition and Synaptic Plasticity in a Mouse Model of Down Syndrome Ameliorated by GABAB Receptor Antagonists

(2012) A. M. Kleschevnikov et al.   JOURNAL OF NEUROSCIENCE

Distributed synergistic plasticity and cerebellar learning

(2012) Zhenyu Gao et al.   NATURE REVIEWS NEUROSCIENCE

The use of mouse models to understand and improve cognitive deficits in Down syndrome

(2011) I. Das et al.   Disease Models & Mechanisms

Scrutinizing ciliopathies by unraveling ciliary interaction networks

(2011) Jeroen van Reeuwijk et al.   HUMAN MOLECULAR GENETICS

APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome

(2011) Stefania Trazzi et al.   HUMAN MOLECULAR GENETICS

Lobule-specific membrane excitability of cerebellar Purkinje cells

(2011) Chang-Hee Kim et al.   JOURNAL OF PHYSIOLOGY-LONDON

Specific targeting of the GABA-A receptor α5 subtype by a selective inverse agonist restores cognitive deficits in Down syndrome mice

(2011) J Braudeau et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Reevaluating the Role of LTD in Cerebellar Motor Learning

(2011) Martijn Schonewille et al.   NEURON

A Small-Molecule Smoothened Agonist Prevents Glucocorticoid-Induced Neonatal Cerebellar Injury

(2011) V. M. Heine et al.   Science Translational Medicine

Role of the Cerebellar Cortex in Conditioned Goal-Directed Behavior

(2010) E. Burguiere et al.   JOURNAL OF NEUROSCIENCE

Intravenous Hedgehog Agonist Induces Proliferation of Neural and Oligodendrocyte Precursors in Rodent Spinal Cord Injury

(2010) Nicholas C Bambakidis et al.   NEUROSURGERY

Elongation Factor 2 and Fragile X Mental Retardation Protein Control the Dynamic Translation of Arc/Arg3.1 Essential for mGluR-LTD

(2008) Sungjin Park et al.   NEURON