Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down’s syndrome

Reducing GABAA  5 Receptor-Mediated Inhibition Rescues Functional and Neuromorphological Deficits in a Mouse Model of Down Syndrome

(2013) C. Martinez-Cue et al.   JOURNAL OF NEUROSCIENCE

Raising cytosolic Cl−in cerebellar granule cells affects their excitability and vestibulo-ocular learning

(2012) Patricia Seja et al.   EMBO JOURNAL

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(2012) Timothée Lionnet et al.   EMBO REPORTS

Deficits in Cognition and Synaptic Plasticity in a Mouse Model of Down Syndrome Ameliorated by GABAB Receptor Antagonists

(2012) A. M. Kleschevnikov et al.   JOURNAL OF NEUROSCIENCE

Tonic Inhibition Enhances Fidelity of Sensory Information Transmission in the Cerebellar Cortex

(2012) I. Duguid et al.   JOURNAL OF NEUROSCIENCE

Extrasynaptic GABAA Receptors: Their Function in the CNS and Implications for Disease

(2012) Stephen G. Brickley et al.   NEURON

Paper 2: EUROCAT public health indicators for congenital anomalies in Europe

(2011) Babak Khoshnood et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes

(2011) Mireia Vilardell et al.   BMC GENOMICS

Abnormal MicroRNA Expression in Ts65Dn Hippocampus and Whole Blood: Contributions to Down Syndrome Phenotypes

(2011) Jennifer Keck-Wherley et al.   DEVELOPMENTAL NEUROSCIENCE

The use of mouse models to understand and improve cognitive deficits in Down syndrome

(2011) I. Das et al.   Disease Models & Mechanisms

Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome

(2011) Tyler K. Best et al.   EXPERIMENTAL NEUROLOGY

Alterations of brain circuits in Down syndrome murine models

(2011) Stefano Gotti et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Molecular basis for the high THIP/gaboxadol sensitivity of extrasynaptic GABAA receptors

(2011) Pratap Meera et al.   JOURNAL OF NEUROPHYSIOLOGY

Profound Desensitization by Ambient GABA Limits Activation of  -Containing GABAA Receptors during Spillover

(2011) D. P. Bright et al.   JOURNAL OF NEUROSCIENCE

Axonal GABAA Receptors Increase Cerebellar Granule Cell Excitability and Synaptic Activity

(2011) J. R. Pugh et al.   JOURNAL OF NEUROSCIENCE

Specific targeting of the GABA-A receptor α5 subtype by a selective inverse agonist restores cognitive deficits in Down syndrome mice

(2011) J Braudeau et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn

(2011) Laura G. Reinholdt et al.   MAMMALIAN GENOME

Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling down syndrome

(2011) Arnaud Duchon et al.   MAMMALIAN GENOME

Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down Syndrome: Activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer

(2011) Mehrdad Faizi et al.   NEUROBIOLOGY OF DISEASE

Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome

(2011) Alexander M. Kleschevnikov et al.   NEUROBIOLOGY OF DISEASE

Trisomy-21 gene dosage over-expression of miRNAs results in the haploinsufficiency of specific target proteins

(2011) Terry S. Elton et al.   RNA Biology

Widespread Proliferation Impairment and Hypocellularity in the Cerebellum of Fetuses with Down Syndrome

(2010) Sandra Guidi et al.   BRAIN PATHOLOGY

Diversity of Structure and Function of α1α6β3δ GABAAReceptors

(2010) Roland Baur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Effects of Axon Initial Segment and Somatodendritic GABAA Receptors on Excitability Measures in Rat Dentate Granule Neurons

(2010) Patricio Rojas et al.   JOURNAL OF NEUROPHYSIOLOGY

Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome

(2010) Lina Chakrabarti et al.   NATURE NEUROSCIENCE

Presynaptic GABAA receptors enhance transmission and LTP induction at hippocampal mossy fiber synapses

(2010) Arnaud Ruiz et al.   NATURE NEUROSCIENCE

miRBase: integrating microRNA annotation and deep-sequencing data

(2010) A. Kozomara et al.   NUCLEIC ACIDS RESEARCH

Sensory representations in cerebellar granule cells

(2009) Alexander Arenz et al.   CURRENT OPINION IN NEUROBIOLOGY

A Critical Period in Cortical Interneuron Neurogenesis in Down Syndrome Revealed by Human Neural Progenitor Cells

(2009) Anita Bhattacharyya et al.   DEVELOPMENTAL NEUROSCIENCE

Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome

(2009) M. Galante et al.   HUMAN MOLECULAR GENETICS

Chromosome 21-derived MicroRNAs Provide an Etiological Basis for Aberrant Protein Expression in Human Down Syndrome Brains

(2009) Donald E. Kuhn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Outwardly Rectifying Tonically Active GABAA Receptors in Pyramidal Cells Modulate Neuronal Offset, Not Gain

(2009) I. Pavlov et al.   JOURNAL OF NEUROSCIENCE

Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of down syndrome

(2008) Pavel V. Belichenko et al.   JOURNAL OF COMPARATIVE NEUROLOGY

GABAA receptor trafficking and its role in the dynamic modulation of neuronal inhibition

(2008) Tija C. Jacob et al.   NATURE REVIEWS NEUROSCIENCE

Functional topography in the human cerebellum: A meta-analysis of neuroimaging studies

(2008) C STOODLEY et al.   NEUROIMAGE

Ultrasonic vocalizations: A tool for behavioural phenotyping of mouse models of neurodevelopmental disorders

(2008) Maria Luisa Scattoni et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Chronic pentylenetetrazole but not donepezil treatment rescues spatial cognition in Ts65Dn mice, a model for Down syndrome

(2008) N. Rueda et al.   NEUROSCIENCE LETTERS

Cerebellar contributions to speech production and speech perception: psycholinguistic and neurobiological perspectives

(2008) Hermann Ackermann   TRENDS IN NEUROSCIENCES