- Home
- Publications
- Publication Search
- Publication Details
Title
Down syndrome: the brain in trisomic mode
Authors
Keywords
-
Journal
NATURE REVIEWS NEUROSCIENCE
Volume 13, Issue 12, Pages 844-858
Publisher
Springer Nature
Online
2012-11-20
DOI
10.1038/nrn3314
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Memantine Normalizes Several Phenotypic Features in the Ts65Dn Mouse Model of Down Syndrome
- (2017) Noemí Rueda et al. JOURNAL OF ALZHEIMERS DISEASE
- Attentional set-shifting in fragile X syndrome
- (2012) M.J.W. Van der Molen et al. BRAIN AND COGNITION
- Effect of DYRK1A activity inhibition on development of neuronal progenitors isolated from Ts65Dn mice
- (2012) Bozena Mazur-Kolecka et al. JOURNAL OF NEUROSCIENCE RESEARCH
- DYRK1A: A master regulatory protein controlling brain growth
- (2012) Fayçal Guedj et al. NEUROBIOLOGY OF DISEASE
- Trisomy of the G protein-coupled K+ channel gene, Kcnj6, affects reward mechanisms, cognitive functions, and synaptic plasticity in mice
- (2012) A. Cooper et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- From Abnormal Hippocampal Synaptic Plasticity in Down Syndrome Mouse Models to Cognitive Disability in Down Syndrome
- (2012) Nathan Cramer et al. NEURAL PLASTICITY
- Relationship Between Brain and Cognitive Processes in Down Syndrome
- (2011) Deny Menghini et al. BEHAVIOR GENETICS
- Paper 2: EUROCAT public health indicators for congenital anomalies in Europe
- (2011) Babak Khoshnood et al. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY
- Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes
- (2011) Mireia Vilardell et al. BMC GENOMICS
- Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling
- (2011) B. Hammerle et al. DEVELOPMENT
- Mouse Models for Down Syndrome-Associated Developmental Cognitive Disabilities
- (2011) Chunhong Liu et al. DEVELOPMENTAL NEUROSCIENCE
- G-Protein-Associated Signal Transduction Processes Are Restored after Postweaning Environmental Enrichment in Ts65Dn, a Down Syndrome Mouse Model
- (2011) C. Baamonde et al. DEVELOPMENTAL NEUROSCIENCE
- Chromatin interaction networks and higher order architectures of eukaryotic genomes
- (2011) Kuljeet Singh Sandhu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Alterations of brain circuits in Down syndrome murine models
- (2011) Stefano Gotti et al. JOURNAL OF CHEMICAL NEUROANATOMY
- Memory Profiles of Down, Williams, and Fragile X Syndromes: Implications for Reading Development
- (2011) Frances A. Conners et al. JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS
- Specific targeting of the GABA-A receptor α5 subtype by a selective inverse agonist restores cognitive deficits in Down syndrome mice
- (2011) J Braudeau et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles
- (2011) M G Loudin et al. LEUKEMIA
- Transcript catalogs of human chromosome 21 and orthologous chimpanzee and mouse regions
- (2011) Xiaolu Sturgeon et al. MAMMALIAN GENOME
- Dendritic Spines and Distributed Circuits
- (2011) Rafael Yuste NEURON
- Altered brain dynamics during voluntary movement in individuals with Down syndrome
- (2011) Naznin Virji-Babul et al. NEUROREPORT
- Reversal of Fragile X Phenotypes by Manipulation of AβPP/Aβ Levels in Fmr1KO Mice
- (2011) Cara J. Westmark et al. PLoS One
- Trisomy-21 gene dosage over-expression of miRNAs results in the haploinsufficiency of specific target proteins
- (2011) Terry S. Elton et al. RNA Biology
- Trisomy 21 and early brain development
- (2011) Tarik F. Haydar et al. TRENDS IN NEUROSCIENCES
- Brain Plasticity and Disease: A Matter of Inhibition
- (2011) Laura Baroncelli et al. NEURAL PLASTICITY
- The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome
- (2010) Arnaud Duchon et al. BEHAVIOURAL BRAIN RESEARCH
- Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome
- (2010) Jason Lockrow et al. BEHAVIOURAL BRAIN RESEARCH
- Updated national birth prevalence estimates for selected birth defects in the United States, 2004-2006
- (2010) Samantha E. Parker et al. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY
- Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice
- (2010) Tao Yu et al. BRAIN RESEARCH
- MNB/DYRK1A as a multiple regulator of neuronal development
- (2010) Francisco J. Tejedor et al. FEBS Journal
- Transcribed dark matter: meaning or myth?
- (2010) C. P. Ponting et al. HUMAN MOLECULAR GENETICS
- Three-dimensional synaptic ultrastructure in the dentate gyrus and hippocampal area CA3 in the Ts65Dn mouse model of down syndrome
- (2010) Victor I. Popov et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Development and validation of the Arizona Cognitive Test Battery for Down syndrome
- (2010) Jamie O. Edgin et al. Journal of Neurodevelopmental Disorders
- NMDA-Mediated Regulation of DSCAM Dendritic Local Translation Is Lost in a Mouse Model of Down's Syndrome
- (2010) A. Alves-Sampaio et al. JOURNAL OF NEUROSCIENCE
- Dyrk1A Overexpression Inhibits Proliferation and Induces Premature Neuronal Differentiation of Neural Progenitor Cells
- (2010) O. Yabut et al. JOURNAL OF NEUROSCIENCE
- Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome
- (2010) P. Bianchi et al. JOURNAL OF NEUROSCIENCE
- Cognitive deficits and associated neurological complications in individuals with Down's syndrome
- (2010) Ira T Lott et al. LANCET NEUROLOGY
- Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome
- (2010) Lina Chakrabarti et al. NATURE NEUROSCIENCE
- Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations
- (2010) Debra Toiber et al. NEUROBIOLOGY OF DISEASE
- Lowering β-Amyloid Levels Rescues Learning and Memory in a Down Syndrome Mouse Model
- (2010) William J. Netzer et al. PLoS One
- Cortical Plasticity Induced by Inhibitory Neuron Transplantation
- (2010) D. G. Southwell et al. SCIENCE
- The piRNA pathway: a fly's perspective on the guardian of the genome
- (2010) Kirsten-André Senti et al. TRENDS IN GENETICS
- Impaired Plasticity at Specific Subset of Striatal Synapses in the Ts65Dn Mouse Model of Down Syndrome
- (2009) Massimiliano Di Filippo et al. BIOLOGICAL PSYCHIATRY
- Enlarged Brain Ventricles and Impaired Neurogenesis in the Ts1Cje and Ts2Cje Mouse Models of Down Syndrome
- (2009) Keiichi Ishihara et al. CEREBRAL CORTEX
- Meiotic behavior of aneuploid chromatin in mouse models of Down syndrome
- (2009) Laura G. Reinholdt et al. CHROMOSOMA
- Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation
- (2009) Nora Göckler et al. FEBS Journal
- The 50th anniversary of the discovery of trisomy 21: The past, present, and future of research and treatment of Down syndrome
- (2009) André Mégarbané et al. GENETICS IN MEDICINE
- Down syndrome--recent progress and future prospects
- (2009) F. K. Wiseman et al. HUMAN MOLECULAR GENETICS
- Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome
- (2009) M. Galante et al. HUMAN MOLECULAR GENETICS
- A new mouse model for the trisomy of the Abcg1–U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome
- (2009) Patricia Lopes Pereira et al. HUMAN MOLECULAR GENETICS
- Chromosome 21-derived MicroRNAs Provide an Etiological Basis for Aberrant Protein Expression in Human Down Syndrome Brains
- (2009) Donald E. Kuhn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The "Down Syndrome Critical Region" Is Sufficient in the Mouse Model to Confer Behavioral, Neurophysiological, and Synaptic Phenotypes Characteristic of Down Syndrome
- (2009) N. P. Belichenko et al. JOURNAL OF NEUROSCIENCE
- Aneuploidy: From a Physiological Mechanism of Variance to Down Syndrome
- (2009) Mara Dierssen et al. PHYSIOLOGICAL REVIEWS
- Green Tea Polyphenols Rescue of Brain Defects Induced by Overexpression of DYRK1A
- (2009) Fayçal Guedj et al. PLoS One
- The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies
- (2009) J. O. Korbel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Restoration of Norepinephrine-Modulated Contextual Memory in a Mouse Model of Down Syndrome
- (2009) A. Salehi et al. Science Translational Medicine
- Targeting Dyrk1A with AAVshRNA Attenuates Motor Alterations in TgDyrk1A, a Mouse Model of Down Syndrome
- (2008) Jon Ortiz-Abalia et al. AMERICAN JOURNAL OF HUMAN GENETICS
- RETRACTED: Human chromosome 21-derived miRNAs are overexpressed in down syndrome brains and hearts
- (2008) Donald E. Kuhn et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Down syndrome and the genes of human chromosome 21: current knowledge and future potentials
- (2008) M. Pritchard et al. CYTOGENETIC AND GENOME RESEARCH
- Genotype–phenotype correlations in Down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21
- (2008) Robert Lyle et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of down syndrome
- (2008) Pavel V. Belichenko et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome
- (2008) E. Morice et al. LEARNING & MEMORY
- Visual and spatial working memory: From boxes to networks
- (2008) H ZIMMER NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Chronic pentylenetetrazole but not donepezil treatment rescues spatial cognition in Ts65Dn mice, a model for Down syndrome
- (2008) N. Rueda et al. NEUROSCIENCE LETTERS
- Phonological Similarity and Lexicality Effects in Children's Verbal Short-Term Memory: Concerns about the Interpretation of Probed Recall Data
- (2008) Christopher Jarrold et al. QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY
- Exploring the forgetting mechanisms in working memory: Evidence from a reasoning span test
- (2008) Satoru Saito et al. QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY
- Effects of chronic administration of SGS-111 during adulthood and during the pre- and post-natal periods on the cognitive deficits of Ts65Dn mice, a model of Down syndrome
- (2007) N RUEDA BEHAVIOURAL BRAIN RESEARCH
- Age-related changes in memory and in acetylcholine functions in the hippocampus in the Ts65Dn mouse, a model of Down syndrome
- (2007) Qing Chang et al. NEUROBIOLOGY OF LEARNING AND MEMORY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation