A mature macrophage is a principal HIV-1 cellular reservoir in humanized mice after treatment with long acting antiretroviral therapy

Creation of a Long-Acting Nanoformulated 2′,3′-Dideoxy-3′-Thiacytidine

(2017) Dongwei Guo et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

CD4 regulatory T cells augment HIV-1 expression of polarized M1 and M2 monocyte derived macrophages

(2017) Tanya O. Robinson et al.   VIROLOGY

Progress Toward HIV Eradication: Case Reports, Current Efforts, and the Challenges Associated with Cure

(2016) Alyssa R. Martin et al.   Annual Review of Medicine

Development and characterization of a long-acting nanoformulated abacavir prodrug

(2016) Dhirender Singh et al.   Nanomedicine

Tissue biology perspective on macrophages

(2016) Yasutaka Okabe et al.   NATURE IMMUNOLOGY

Immuno-Pharmacological Targeting of Virus-Containing Compartments in HIV-1-Infected Macrophages

(2016) Francesca Graziano et al.   TRENDS IN MICROBIOLOGY

HIV-1 cellular and tissue replication patterns in infected humanized mice

(2016) Mariluz Araínga et al.   Scientific Reports

HIV Reservoir Dynamics in the Face of Highly Active Antiretroviral Therapy

(2015) Cecilia T. Costiniuk et al.   AIDS PATIENT CARE AND STDS

Relationship Between Genital Drug Concentrations and Cervical Cellular Immune Activation and Reconstitution in HIV-1-Infected Women on a Raltegravir Versus a Boosted Atazanavir Regimen

(2015) Amie L. Meditz et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

An Evolutionary Role for HIV Latency in Enhancing Viral Transmission

(2015) Igor M. Rouzine et al.   CELL

Tissue-resident macrophages: then and now

(2015) Luke C. Davies et al.   IMMUNOLOGY

Early Initiation of Antiretroviral Therapy Can Functionally Control Productive HIV-1 Infection in Humanized-BLT Mice

(2015) Qingsheng Li et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Ex vivo analysis identifies effective HIV-1 latency–reversing drug combinations

(2015) Gregory M. Laird et al.   JOURNAL OF CLINICAL INVESTIGATION

The Remarkable Stability of the Latent Reservoir for HIV-1 in Resting Memory CD4+T Cells

(2015) Janet M. Siliciano et al.   JOURNAL OF INFECTIOUS DISEASES

Human Mucosal Mast Cells Capture HIV-1 and Mediate Viraltrans-Infection of CD4+T Cells

(2015) Ai-Ping Jiang et al.   JOURNAL OF VIROLOGY

Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy

(2015) Mary F. Kearney et al.   Retrovirology

Opposing regulation of endolysosomal pathways by long-acting nanoformulated antiretroviral therapy and HIV-1 in human macrophages

(2015) Mariluz Araínga et al.   Retrovirology

The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells

(2015) Nitasha A. Kumar et al.   Retrovirology

Towards an HIV-1 cure: measuring the latent reservoir

(2015) Katherine M. Bruner et al.   TRENDS IN MICROBIOLOGY

Studies of retroviral infection in humanized mice

(2015) Matthew D. Marsden et al.   VIROLOGY

Impacts of Humanized Mouse Models on the Investigation of HIV-1 Infection: Illuminating the Roles of Viral Accessory Proteins in Vivo

(2015) Eri Yamada et al.   Viruses-Basel

Eradication of HIV-1 from the Macrophage Reservoir: An Uncertain Goal?

(2015) Wasim Abbas et al.   Viruses-Basel

Macrophage Infection via Selective Capture of HIV-1-Infected CD4+ T Cells

(2014) Amy E. Baxter et al.   Cell Host & Microbe

Development of HIV Reservoir Targeted Long Acting Nanoformulated Antiretroviral Therapies

(2014) Benson Edagwa et al.   CURRENT MEDICINAL CHEMISTRY

Origin of the Transmitted Virus in HIV Infection: Infected Cells Versus Cell-Free Virus

(2014) M. Sagar   JOURNAL OF INFECTIOUS DISEASES

Increased Stability and Limited Proliferation of CD4+ Central Memory T Cells Differentiate Nonprogressive Simian Immunodeficiency Virus (SIV) Infection of Sooty Mangabeys from Progressive SIV Infection of Rhesus Macaques

(2014) C. S. McGary et al.   JOURNAL OF VIROLOGY

Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1

(2014) Alison L. Hill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Persistence of Virus Reservoirs in ART-Treated SHIV-Infected Rhesus Macaques after Autologous Hematopoietic Stem Cell Transplant

(2014) Maud Mavigner et al.   PLoS Pathogens

Limited HIV Infection of Central Memory and Stem Cell Memory CD4+ T Cells Is Associated with Lack of Progression in Viremic Individuals

(2014) Nichole R. Klatt et al.   PLoS Pathogens

HIV-1 infection of hematopoietic progenitor cells in vivo in humanized mice

(2013) C. C. Nixon et al.   BLOOD

Interleukin-7 promotes HIV persistence during antiretroviral therapy

(2013) C. Vandergeeten et al.   BLOOD

An Integrated Overview of HIV-1 Latency

(2013) Debbie S. Ruelas et al.   CELL

CD4+T-cell depletion in HIV infection: mechanisms of immunological failure

(2013) Afam A. Okoye et al.   IMMUNOLOGICAL REVIEWS

Recent Advances in Humanized Mice: Accelerating the Development of an HIV Vaccine

(2013) A. M. Tager et al.   JOURNAL OF INFECTIOUS DISEASES

Combinatorial assessments of brain tissue metabolomics and histopathology in rodent models of human immunodeficiency virus infection

(2013) Adrian A. Epstein et al.   Journal of Neuroimmune Pharmacology

Overcoming pharmacologic sanctuaries

(2013) Theodore J. Cory et al.   Current Opinion in HIV and AIDS

Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice

(2012) Prasanta K. Dash et al.   AIDS

The role of cytokines in the establishment, persistence and eradication of the HIV reservoir

(2012) Claire Vandergeeten et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Can Humanized Mice Reflect the Complex Pathobiology of HIV-Associated Neurocognitive Disorders?

(2012) Santhi Gorantla et al.   Journal of Neuroimmune Pharmacology

Animal models for HIV/AIDS research

(2012) Theodora Hatziioannou et al.   NATURE REVIEWS MICROBIOLOGY

Macrophage Bridging Conduit Trafficking of HIV-1 Through the Endoplasmic Reticulum and Golgi Network

(2011) Irena Kadiu et al.   JOURNAL OF PROTEOME RESEARCH

Low levels of SIV infection in sooty mangabey central memory CD4+ T cells are associated with limited CCR5 expression

(2011) Mirko Paiardini et al.   NATURE MEDICINE

Rebound of residual plasma viremia after initial decrease following addition of intravenous immunoglobulin to effective antiretroviral treatment of HIV

(2011) Tomas Mellberg et al.   AIDS Research and Therapy

Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication

(2010) Tae-Wook Chun et al.   AIDS

Links between Progressive HIV-1 Infection of Humanized Mice and Viral Neuropathogenesis

(2010) Santhi Gorantla et al.   AMERICAN JOURNAL OF PATHOLOGY

CD8+ Cell Depletion Accelerates HIV-1 Immunopathology in Humanized Mice

(2010) S. Gorantla et al.   JOURNAL OF IMMUNOLOGY

HIV-1 Resistance to CCR5 Antagonists Associated with Highly Efficient Use of CCR5 and Altered Tropism on Primary CD4+ T Cells

(2010) J. M. Pfaff et al.   JOURNAL OF VIROLOGY

HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals

(2010) D. Trono et al.   SCIENCE

Increased Monocyte Turnover from Bone Marrow Correlates with Severity of SIV Encephalitis and CD163 Levels in Plasma

(2010) Tricia H. Burdo et al.   PLoS Pathogens

HIV and SIV infection: the role of cellular restriction and immune responses in viral replication and pathogenesis

(2009) KENNETH C. WILLIAMS et al.   APMIS

Development of a long-acting injectable formulation with nanoparticles of rilpivirine (TMC278) for HIV treatment

(2009) Lieven Baert et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

Selective infection of CD4+ effector memory T lymphocytes leads to preferential depletion of memory T lymphocytes in R5 HIV-1-infected humanized NOD/SCID/IL-2Rγnull mice

(2009) Chuanyi Nie et al.   VIROLOGY

Intestinal double-positive CD4+CD8+ T cells of neonatal rhesus macaques are proliferating, activated memory cells and primary targets for SIVMAC251 infection

(2008) X. Wang et al.   BLOOD

Highly Sensitive Methods Based on Seminested Real-Time Reverse Transcription-PCR for Quantitation of Human Immunodeficiency Virus Type 1 Unspliced and Multiply Spliced RNA and Proviral DNA

(2008) A. O. Pasternak et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Monocyte/macrophage trafficking in acquired immunodeficiency syndrome encephalitis: Lessons from human and nonhuman primate studies

(2008) Tracy Fischer-Smith et al.   JOURNAL OF NEUROVIROLOGY