Opposing regulation of endolysosomal pathways by long-acting nanoformulated antiretroviral therapy and HIV-1 in human macrophages

Pharmacodynamics of long-acting folic acid-receptor targeted ritonavir-boosted atazanavir nanoformulations

(2015) Pavan Puligujja et al.   BIOMATERIALS

Pharmacokinetics, Biodistribution, and Toxicity of Folic Acid-Coated Antiretroviral Nanoformulations

(2014) Nagsen Gautam et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Quantitative Proteomics by SWATH-MS Reveals Altered Expression of Nucleic Acid Binding and Regulatory Proteins in HIV-1-Infected Macrophages

(2014) Nicole A. Haverland et al.   JOURNAL OF PROTEOME RESEARCH

Multi-enzyme digestion FASP and the ‘Total Protein Approach’-based absolute quantification of the Escherichia coli proteome

(2014) Jacek R. Wiśniewski et al.   Journal of Proteomics

Endosomal Trafficking of Nanoformulated Antiretroviral Therapy Facilitates Drug Particle Carriage and HIV Clearance

(2014) D. Guo et al.   JOURNAL OF VIROLOGY

TIM-family proteins inhibit HIV-1 release

(2014) M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA binding to the HIV-1 Gag protein inhibits Gag assembly and virus production

(2014) Antony K. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The phosphorylation of HIV-1 Gag by atypical protein kinase C facilitates viral infectivity by promoting Vpr incorporation into virions

(2014) Ayumi Kudoh et al.   Retrovirology

Adjunctive and long-acting nanoformulated antiretroviral therapies for HIV-associated neurocognitive disorders

(2014) Howard E. Gendelman et al.   Current Opinion in HIV and AIDS

Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection

(2014) Milan Raska et al.   AIDS Research and Therapy

Preclinical Pharmacokinetics and Tissue Distribution of Long-Acting Nanoformulated Antiretroviral Therapy

(2013) Nagsen Gautam et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Organization and regulation of intracellular plasma membrane-connected HIV-1 assembly compartments in macrophages

(2013) Petra Mlcochova et al.   BMC BIOLOGY

New Approaches to Antiretroviral Drug Delivery: Challenges and Opportunities Associated with the Use of Long-Acting Injectable Agents

(2013) Marta Boffito et al.   DRUGS

Genetic, Transcriptomic, and Epigenetic Studies of HIV-Associated Neurocognitive Disorder

(2013) Andrew J. Levine et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Rab Family Proteins Regulate the Endosomal Trafficking and Function of RGS4

(2013) Guillaume Bastin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells

(2013) P. Mendoza et al.   JOURNAL OF CELL SCIENCE

Human Plasmacytoid Dendritic Cells Efficiently Capture HIV-1 Envelope Glycoproteins via CD4 for Antigen Presentation

(2013) K. J. Sandgren et al.   JOURNAL OF IMMUNOLOGY

Characterization of tetraspanins CD9, CD53, CD63, and CD81 in monocytes and macrophages in HIV-1 infection

(2013) Emma Tippett et al.   JOURNAL OF LEUKOCYTE BIOLOGY

iTRAQ Analysis with Paul Ion Trap–Obstacle Solved

(2013) Anna Drabik et al.   JOURNAL OF PROTEOME RESEARCH

The Conserved Set of Host Proteins Incorporated into HIV-1 Virions Suggests a Common Egress Pathway in Multiple Cell Types

(2013) Michael E. Linde et al.   JOURNAL OF PROTEOME RESEARCH

Proteomic Analysis of Early HIV-1 Nucleoprotein Complexes

(2013) Cameron J. Schweitzer et al.   JOURNAL OF PROTEOME RESEARCH

Regulation of Hepatitis B Virus Infection by Rab5, Rab7, and the Endolysosomal Compartment

(2013) A. Macovei et al.   JOURNAL OF VIROLOGY

Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections

(2013) Pavan Puligujja et al.   Nanomedicine-Nanotechnology Biology and Medicine

Rab6a/a’ Are Important Golgi Regulators of Pro-Inflammatory TNF Secretion in Macrophages

(2013) Massimo Micaroni et al.   PLoS One

Microparticle-associated tissue factor is recycled by endothelial cells resulting in enhanced surface tissue factor activity

(2013) Yupei Xiao et al.   THROMBOSIS AND HAEMOSTASIS

The HIV-1-containing macrophage compartment: a perfect cellular niche?

(2013) Joshua Tan et al.   TRENDS IN MICROBIOLOGY

Long-acting injectable antiretrovirals for HIV treatment and prevention

(2013) William R. Spreen et al.   Current Opinion in HIV and AIDS

Rab11-FIP1C and Rab14 Direct Plasma Membrane Sorting and Particle Incorporation of the HIV-1 Envelope Glycoprotein Complex

(2013) Mingli Qi et al.   PLoS Pathogens

APOBEC3G Inhibits MicroRNA-mediated Repression of Translation by Interfering with the Interaction between Argonaute-2 and MOV10

(2012) Chao Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacodynamic and Antiretroviral Activities of Combination Nanoformulated Antiretrovirals in HIV-1–Infected Human Peripheral Blood Lymphocyte–Reconstituted Mice

(2012) Upal Roy et al.   JOURNAL OF INFECTIOUS DISEASES

Bacterial Pathogens Commandeer Rab GTPases to Establish Intracellular Niches

(2012) Mary-Pat Stein et al.   TRAFFIC

Proteolytic processing of SDF-1α by matrix metalloproteinase-2 impairs CXCR4 signaling and reduces neural progenitor cell migration

(2012) Hui Peng et al.   Protein & Cell

Release of TNF-αfrom macrophages is mediated by small GTPase Rab37

(2011) Ryoichi Mori et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Macrophage Bridging Conduit Trafficking of HIV-1 Through the Endoplasmic Reticulum and Golgi Network

(2011) Irena Kadiu et al.   JOURNAL OF PROTEOME RESEARCH

Architecture and Regulation of the HIV-1 Assembly and Holding Compartment in Macrophages

(2011) S. Welsch et al.   JOURNAL OF VIROLOGY

Macrophage endocytic trafficking of antiretroviral nanoparticles

(2011) Irena Kadiu et al.   Nanomedicine

Rab7A Is Required for Efficient Production of Infectious HIV-1

(2011) Marina Caillet et al.   PLoS Pathogens

Interleukin-6

(2010) STEVEN C. CLARK   Annals of the New York Academy of Sciences

Identification of the Switch in Early-to-Late Endosome Transition

(2010) Dmitry Poteryaev et al.   CELL

The role of Rab5a GTPase in endocytosis and post-endocytic trafficking of the hCG-human luteinizing hormone receptor complex

(2010) Thippeswamy Gulappa et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages

(2010) Ari S. Nowacek et al.   JOURNAL OF CONTROLLED RELEASE

Nanoformulated Antiretroviral Drug Combinations Extend Drug Release and Antiretroviral Responses in HIV-1-Infected Macrophages: Implications for NeuroAIDS Therapeutics

(2010) Ari S. Nowacek et al.   Journal of Neuroimmune Pharmacology

Live cell visualization of the interactions between HIV-1 Gag and the cellular RNA-binding protein Staufen1

(2010) Miroslav P Milev et al.   Retrovirology

HIV-1 assembly in macrophages

(2010) Philippe Benaroch et al.   Retrovirology

HIV-1 Tat Addresses Dendritic Cells to Induce a Predominant Th1-Type Adaptive Immune Response That Appears Prevalent in the Asymptomatic Stage of Infection

(2009) E. Fanales-Belasio et al.   JOURNAL OF IMMUNOLOGY

Macrophage Delivery of Nanoformulated Antiretroviral Drug to the Brain in a Murine Model of NeuroAIDS

(2009) H. Dou et al.   JOURNAL OF IMMUNOLOGY

NanoART synthesis, characterization, uptake, release and toxicology for human monocyte–macrophage drug delivery

(2009) Ari S Nowacek et al.   Nanomedicine

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Statin-induced inhibition of HIV-1 release from latently infected U1 cells reveals a critical role for protein prenylation in HIV-1 replication

(2008) Tohti Amet et al.   MICROBES AND INFECTION

HIV-1 Nef Induces a Rab11-Dependent Routing of Endocytosed Immune Costimulatory Proteins CD80 and CD86 to the Golgi

(2008) Ashutosh Chaudhry et al.   TRAFFIC