Development and characterization of a long-acting nanoformulated abacavir prodrug

The mixed lineage kinase-3 inhibitor URMC-099 improves therapeutic outcomes for long-acting antiretroviral therapy

(2016) Gang Zhang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Persistent HIV-1 replication maintains the tissue reservoir during therapy

(2016) Ramon Lorenzo-Redondo et al.   NATURE

Residual inflammation and viral reservoirs

(2016) Marta Massanella et al.   Current Opinion in HIV and AIDS

N -myristoyltransferase 1 enhances human immunodeficiency virus replication through regulation of viral RNA expression level

(2015) Hikaru Ohta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pharmacodynamics of long-acting folic acid-receptor targeted ritonavir-boosted atazanavir nanoformulations

(2015) Pavan Puligujja et al.   BIOMATERIALS

Efficacy and safety of abacavir-containing combination antiretroviral therapy as first-line treatment of HIV infected children and adolescents: a systematic review and meta-analysis

(2015) Olatunji O. Adetokunboh et al.   BMC INFECTIOUS DISEASES

Improving bioavailability and biodistribution of anti-HIV chemotherapy

(2015) Giovanna Giacalone et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Development of albumin-based nanoparticles for the delivery of abacavir

(2015) Barnabas Wilson et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Shape and size-dependent immune response to antigen-carrying nanoparticles

(2015) Sunny Kumar et al.   JOURNAL OF CONTROLLED RELEASE

HIV reservoirs as obstacles and opportunities for an HIV cure

(2015) Tae-Wook Chun et al.   NATURE IMMUNOLOGY

Opposing regulation of endolysosomal pathways by long-acting nanoformulated antiretroviral therapy and HIV-1 in human macrophages

(2015) Mariluz Araínga et al.   Retrovirology

Cost-Effectiveness of Dolutegravir/Abacavir/Lamivudine in Hiv-1 Treatment Naive Patients in France

(2015) G Pialoux et al.   VALUE IN HEALTH

The Potential of the CNS as a Reservoir for HIV-1 Infection: Implications for HIV Eradication

(2015) Alessandro F. Fois et al.   Current HIV/AIDS Reports

Improved Safety, Bioavailability and Pharmacokinetics of Zidovudine through Lactoferrin Nanoparticles during Oral Administration in Rats

(2015) Prashant Kumar et al.   PLoS One

HIV drug resistance detected during low-level viraemia is associated with subsequent virologic failure

(2014) Luke C. Swenson et al.   AIDS

Pharmacokinetics, Biodistribution, and Toxicity of Folic Acid-Coated Antiretroviral Nanoformulations

(2014) Nagsen Gautam et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Endosomal Trafficking of Nanoformulated Antiretroviral Therapy Facilitates Drug Particle Carriage and HIV Clearance

(2014) D. Guo et al.   JOURNAL OF VIROLOGY

Comparative biophysical properties of tenofovir-loaded, thiolated and nonthiolated chitosan nanoparticles intended for HIV prevention

(2014) Jianing Meng et al.   Nanomedicine

Current prodrug strategies for improving oral absorption of nucleoside analogues

(2014) Youxi Zhang et al.   Asian Journal of Pharmaceutical Sciences

Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections

(2013) Pavan Puligujja et al.   Nanomedicine-Nanotechnology Biology and Medicine

Long-acting injectable antiretrovirals for HIV treatment and prevention

(2013) William R. Spreen et al.   Current Opinion in HIV and AIDS

Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice

(2012) Prasanta K. Dash et al.   AIDS

Spray drying tenofovir loaded mucoadhesive and pH-sensitive microspheres intended for HIV prevention

(2012) Tao Zhang et al.   ANTIVIRAL RESEARCH

Anti-HIV-1 nanotherapeutics: promises and challenges for the future

(2012) Supriya Mahajan et al.   International Journal of Nanomedicine

Synthesis and Biological Evaluation of Fatty Acyl Ester Derivatives of (−)-2′,3′-Dideoxy-3′-thiacytidine

(2012) Hitesh K. Agarwal et al.   JOURNAL OF MEDICINAL CHEMISTRY

Preexposure Prophylaxis for HIV Infection among African Women

(2012) Lut Van Damme et al.   NEW ENGLAND JOURNAL OF MEDICINE

Combinatorial Approaches to the Prevention and Treatment of HIV-1 Infection

(2011) Vanessa Pirrone et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Surface modified nevirapine nanosuspensions for viral reservoir targeting: In vitro and in vivo evaluation

(2011) Ranjita Shegokar et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Low-Frequency HIV-1 Drug Resistance Mutations and Risk of NNRTI-Based Antiretroviral Treatment Failure

(2011) Jonathan Z. Li   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models

(2010) Andries M. Bergman et al.   INVESTIGATIONAL NEW DRUGS

Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages

(2010) Ari S. Nowacek et al.   JOURNAL OF CONTROLLED RELEASE

Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men

(2010) Robert M. Grant et al.   NEW ENGLAND JOURNAL OF MEDICINE

Macrophages Recognize Size and Shape of Their Targets

(2010) Nishit Doshi et al.   PLoS One

NanoART synthesis, characterization, uptake, release and toxicology for human monocyte–macrophage drug delivery

(2009) Ari S Nowacek et al.   Nanomedicine

Abacavir Hypersensitivity Reaction: an Update

(2008) Christine A Hughes et al.   ANNALS OF PHARMACOTHERAPY

A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages

(2008) W. Xia et al.   BLOOD

Impact of High and Low Folate Diets on Tissue Folate Receptor Levels and Antitumor Responses Toward Folate-Drug Conjugates

(2008) C. P. Leamon et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS