Amyloidogenesis of Tau protein

Alzheimer’s Disease: Characterization of the Brain Sites of the Initial Tau Cytoskeletal Pathology Will Improve the Success of Novel Immunological Anti-Tau Treatment Approaches

(2017) Udo Rüb et al.   JOURNAL OF ALZHEIMERS DISEASE

A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies

(2017) Miranda E. Orr et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A Dual Pathogenic Mechanism Links Tau Acetylation to Sporadic Tauopathy

(2017) Hanna Trzeciakiewicz et al.   Scientific Reports

How Does Hyperphopsphorylation Promote Tau Aggregation and Modulate Filament Structure and Stability?

(2016) Liang Xu et al.   ACS Chemical Neuroscience

Widespread tau seeding activity at early Braak stages

(2016) Jennifer L. Furman et al.   ACTA NEUROPATHOLOGICA

PrP aggregation can be seeded by pre-formed recombinant PrP amyloid fibrils without the replication of infectious prions

(2016) Rona M. Barron et al.   ACTA NEUROPATHOLOGICA

Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo

(2016) Bruno Vasconcelos et al.   ACTA NEUROPATHOLOGICA

Appraisal of role of the polyanionic inducer length on amyloid formation by 412-residue 1N4R Tau protein: A comparative study

(2016) Abolfazl Jangholi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Tau Oligomers Associate with Inflammation in the Brain and Retina of Tauopathy Mice and in Neurodegenerative Diseases

(2016) Ashley N. Nilson et al.   JOURNAL OF ALZHEIMERS DISEASE

Fracture and Growth Are Competing Forces Determining the Fate of Conformers in Tau Fibril Populations

(2016) Virginia Meyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determination of critical nucleation number for a single nucleation amyloid-β aggregation model

(2016) Preetam Ghosh et al.   MATHEMATICAL BIOSCIENCES

Mammalian prions and their wider relevance in neurodegenerative diseases

(2016) John Collinge   NATURE

The activities of amyloids from a structural perspective

(2016) Roland Riek et al.   NATURE

Analysis of isoform-specific tau aggregates suggests a common toxic mechanism involving similar pathological conformations and axonal transport inhibition

(2016) Kristine Cox et al.   NEUROBIOLOGY OF AGING

Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss

(2016) Tara E. Tracy et al.   NEURON

Tau Prion Strains Dictate Patterns of Cell Pathology, Progression Rate, and Regional Vulnerability In Vivo

(2016) Sarah K. Kaufman et al.   NEURON

Remodeling of the conformational ensemble of the repeat domain of tau by an aggregation enhancer

(2016) Elias Akoury et al.   PROTEIN SCIENCE

Cell Biology of Prions and Prionoids: A Status Report

(2016) Adriano Aguzzi et al.   TRENDS IN CELL BIOLOGY

Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity

(2016) Kanae Ando et al.   PLoS Genetics

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory

(2016) M. Fá et al.   Scientific Reports

Folding of the Tau Protein on Microtubules

(2015) Harindranath Kadavath et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Microtubule-Binding R3 Fragment from Tau Self-Assembles into Giant Multistranded Amyloid Ribbons

(2015) Jozef Adamcik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

RNA Binds to Tau Fibrils and Sustains Template-Assisted Growth

(2015) Paul D. Dinkel et al.   BIOCHEMISTRY

The role of tau in the pathological process and clinical expression of Huntington’s disease

(2015) Romina Vuono et al.   BRAIN

Closing the tau loop: the missing tau mutation

(2015) Allan McCarthy et al.   BRAIN

Cellular factors modulating the mechanism of tau protein aggregation

(2015) Sarah N. Fontaine et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity

(2015) S. Wegmann et al.   EMBO JOURNAL

The twenty-four KDa C-terminal tau fragment increases with aging in tauopathy mice: implications of prion-like properties

(2015) Shin-Ei Matsumoto et al.   HUMAN MOLECULAR GENETICS

Tau Assembly: The Dominant Role of PHF6 (VQIVYK) in Microtubule Binding Region Repeat R3

(2015) Pritam Ganguly et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Aβ “Stretching-and-Packing” Cross-Seeding Mechanism Can Trigger Tau Protein Aggregation

(2015) Ruxi Qi et al.   Journal of Physical Chemistry Letters

A novel Alzheimer disease locus located near the gene encoding tau protein

(2015) G Jun et al.   MOLECULAR PSYCHIATRY

Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy

(2015) Asami Kondo et al.   NATURE

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

(2015) Sang-Won Min et al.   NATURE MEDICINE

Inhibition of amyloid-β plaque formation by α-synuclein

(2015) Teresa Bachhuber et al.   NATURE MEDICINE

Tau and neurodegenerative disease: the story so far

(2015) Khalid Iqbal et al.   Nature Reviews Neurology

Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo

(2015) Marie Violet et al.   NEUROBIOLOGY OF DISEASE

Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice

(2015) Eve Peeraer et al.   NEUROBIOLOGY OF DISEASE

Amyloid Polymorphism: Structural Basis and Neurobiological Relevance

(2015) Robert Tycko   NEURON

Invited review: Frontotemporal dementia caused bymicrotubule-associated protein taugene (MAPT) mutations: a chameleon for neuropathology and neuroimaging

(2015) Bernardino Ghetti et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Invited review: Neuropathology of tauopathies: principles and practice

(2015) G. G. Kovacs   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Tau stabilizes microtubules by binding at the interface between tubulin heterodimers

(2015) Harindranath Kadavath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation and aggregation of intrinsically disordered peptides

(2015) Zachary A. Levine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled A , tau, and  -synuclein

(2015) M. Goedert   SCIENCE

Rescue from tau-induced neuronal dysfunction produces insoluble tau oligomers

(2015) Catherine M. Cowan et al.   Scientific Reports

Is there a risk of prion-like disease transmission by Alzheimer- or Parkinson-associated protein particles?

(2014) Michael Beekes et al.   ACTA NEUROPATHOLOGICA

Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity

(2014) Kristen E. Funk et al.   BIOCHEMICAL JOURNAL

Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action

(2014) G. Elif Karagöz et al.   CELL

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

Mutant huntingtin alters Tau phosphorylation and subcellular distribution

(2014) David Blum et al.   HUMAN MOLECULAR GENETICS

Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles

(2014) D. L. Castillo-Carranza et al.   JOURNAL OF NEUROSCIENCE

Interactions between Amyloid-β and Tau Fragments Promote Aberrant Aggregates: Implications for Amyloid Toxicity

(2014) Thanh D. Do et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Huntington's disease is a four-repeat tauopathy with tau nuclear rods

(2014) Marta Fernández-Nogales et al.   NATURE MEDICINE

Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease

(2014) Zhentao Zhang et al.   NATURE MEDICINE

Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases

(2014) Jing L Guo et al.   NATURE MEDICINE

Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease

(2014) Meredith A. Chabrier et al.   NEUROBIOLOGY OF DISEASE

Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies

(2014) David W. Sanders et al.   NEURON

Frontotemporal dementia with parkinsonism linked to chromosome 17 with theMAPT R406W mutation presenting with a broad distribution of abundant senile plaques

(2014) Chiho Ishida et al.   NEUROPATHOLOGY

Inhibition of Tau Aggregation by Three Aspergillus nidulans Secondary Metabolites: 2,ω-Dihydroxyemodin, Asperthecin, and Asperbenzaldehyde

(2014) Smita Paranjape et al.   PLANTA MEDICA

SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination

(2014) Hong-Bin Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serial propagation of distinct strains of A  prions from Alzheimer's disease patients

(2014) J. C. Watts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physical and structural basis for polymorphism in amyloid fibrils

(2014) Robert Tycko   PROTEIN SCIENCE

Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients

(2014) Yu-Sheng Fang et al.   Nature Communications

Tau-induced neurodegeneration: mechanisms and targets

(2014) Cindy Beharry et al.   Neuroscience Bulletin

Acetylation: a new key to unlock tau’s role in neurodegeneration

(2014) Casey Cook et al.   Alzheimers Research & Therapy

Biology and Genetics of Prions Causing Neurodegeneration

(2013) Stanley B. Prusiner   Annual Review of Genetics

Conformational Features of Tau Fibrils from Alzheimer’s Disease Brain Are Faithfully Propagated by Unmodified Recombinant Protein

(2013) Olga A. Morozova et al.   BIOCHEMISTRY

Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons

(2013) Jing L. Guo et al.   CELL

Molecular insights into the reversible formation of tau protein fibrils

(2013) Yin Luo et al.   CHEMICAL COMMUNICATIONS

The role of protein glycosylation in Alzheimer disease

(2013) Sophia Schedin-Weiss et al.   FEBS Journal

Rapid Accumulation of Endogenous Tau Oligomers in a Rat Model of Traumatic Brain Injury

(2013) Bridget E. Hawkins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glial and Neuronal Tau Pathology in Tauopathies

(2013) Isidre Ferrer et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy

(2013) M. Iba et al.   JOURNAL OF NEUROSCIENCE

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

(2013) Mathias Jucker et al.   NATURE

Anti-Tau Antibodies that Block Tau Aggregate Seeding In Vitro Markedly Decrease Pathology and Improve Cognition In Vivo

(2013) Kiran Yanamandra et al.   NEURON

Brain homogenates from human tauopathies induce tau inclusions in mouse brain

(2013) Florence Clavaguera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

(2013) B. B. Holmes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration

(2013) E.-M. Mandelkow et al.   Cold Spring Harbor Perspectives in Medicine

The Evolution of Transmissible Prions: The Role of Deformed Templating

(2013) Natallia Makarava et al.   PLoS Pathogens

Cross-Seeding of Misfolded Proteins: Implications for Etiology and Pathogenesis of Protein Misfolding Diseases

(2013) Rodrigo Morales et al.   PLoS Pathogens

Tau protein phosphatases in Alzheimer's disease: The leading role of PP2A

(2012) Ludovic Martin et al.   AGEING RESEARCH REVIEWS

The Synaptic Accumulation of Hyperphosphorylated Tau Oligomers in Alzheimer Disease Is Associated With Dysfunction of the Ubiquitin-Proteasome System

(2012) Hwan-Ching Tai et al.   AMERICAN JOURNAL OF PATHOLOGY

Stimulation of autophagy is neuroprotective in a mouse model of human tauopathy

(2012) Véronique Schaeffer et al.   Autophagy

FTDP-17 Tau Mutations Induce Distinct Effects on Aggregation and Microtubule Interactions

(2012) Benjamin Combs et al.   BIOCHEMISTRY

Cross-Seeding of Fibrils from Two Types of Insulin Induces New Amyloid Strains

(2012) Weronika Surmacz-Chwedoruk et al.   BIOCHEMISTRY

Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies

(2012) David J. Irwin et al.   BRAIN

Transmissible Proteins: Expanding the Prion Heresy

(2012) Claudio Soto   CELL

Proline Isomer-Specific Antibodies Reveal the Early Pathogenic Tau Conformation in Alzheimer's Disease

(2012) Kazuhiro Nakamura et al.   CELL

Limited cleavage of tau with matrix-metalloproteinase MMP-9, but not MMP-3, enhances tau oligomer formation

(2012) G. Nübling et al.   EXPERIMENTAL NEUROLOGY

MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies

(2012) Daniah Trabzuni et al.   HUMAN MOLECULAR GENETICS

Cross-seeding and Conformational Selection between Three- and Four-repeat Human Tau Proteins

(2012) Xiang Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons

(2012) Jessica W. Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trans-cellular Propagation of Tau Aggregation by Fibrillar Species

(2012) Najla Kfoury et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β-Sheet Core of Tau Paired Helical Filaments Revealed by Solid-State NMR

(2012) Venita Daebel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Is tau ready for admission to the prion club?

(2012) Garth F. Hall et al.   Prion

The fuzzy coat of pathological human Tau fibrils is a two-layered polyelectrolyte brush

(2012) Susanne Wegmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic View of a Toxic Amyloid Small Oligomer

(2012) Arthur Laganowsky et al.   SCIENCE

A Unifying Role for Prions in Neurodegenerative Diseases

(2012) S. B. Prusiner   SCIENCE

Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

(2012) Cristian A. Lasagna-Reeves et al.   Scientific Reports

Dual modification of Alzheimer’s disease PHF-tau protein by lysine methylation and ubiquitylation: a mass spectrometry approach

(2011) Stefani N. Thomas et al.   ACTA NEUROPATHOLOGICA

Tyrosine Nitration within the Proline-Rich Region of Tau in Alzheimer's Disease

(2011) Juan F. Reyes et al.   AMERICAN JOURNAL OF PATHOLOGY

Synergistic Interactions between Repeats in Tau Protein and Aβ Amyloids May Be Responsible for Accelerated Aggregation via Polymorphic States

(2011) Yifat Miller et al.   BIOCHEMISTRY

Variations in Filament Conformation Dictate Seeding Barrier between Three- and Four-Repeat Tau

(2011) Paul D. Dinkel et al.   BIOCHEMISTRY

Tau Protein Assembles into Isoform- and Disulfide-dependent Polymorphic Fibrils with Distinct Structural Properties

(2011) Yoshiaki Furukawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Understanding the Kinetic Roles of the Inducer Heparin and of Rod-like Protofibrils during Amyloid Fibril Formation by Tau Protein

(2011) Gayathri Ramachandran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The toxicity of tau in Alzheimer disease: turnover, targets and potential therapeutics

(2011) Susanne M. Pritchard et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain

(2011) Allal Boutajangout et al.   JOURNAL OF NEUROCHEMISTRY

Truncation of tau at E391 Promotes Early Pathologic Changes in Transgenic Mice

(2011) Pamela J. McMillan et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Induction of Intracellular Tau Aggregation Is Promoted by  -Synuclein Seeds and Provides Novel Insights into the Hyperphosphorylation of Tau

(2011) E. A. Waxman et al.   JOURNAL OF NEUROSCIENCE

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

(2011) Cristian A Lasagna-Reeves et al.   Molecular Neurodegeneration

Temporary secondary structures in tau, an intrinsically disordered protein

(2011) Anna Battisti et al.   MOLECULAR SIMULATION

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrils

(2011) Jan Bieschke et al.   Nature Chemical Biology

Corticobasal degeneration: a pathologically distinct 4R tauopathy

(2011) Naomi Kouri et al.   Nature Reviews Neurology

Autophagic degradation of tau in primary neurons and its enhancement by trehalose

(2011) Ulrike Krüger et al.   NEUROBIOLOGY OF AGING

Post-translational modifications of tau protein: Implications for Alzheimer's disease

(2011) Ludovic Martin et al.   NEUROCHEMISTRY INTERNATIONAL

Soluble amyloid  -protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

(2011) M. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human apoE Isoforms Differentially Regulate Brain Amyloid-  Peptide Clearance

(2011) J. M. Castellano et al.   Science Translational Medicine

The acetylation of tau inhibits its function and promotes pathological tau aggregation

(2011) Todd J. Cohen et al.   Nature Communications

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Tau in Alzheimer Disease and Related Tauopathies

(2010) K. Iqbal et al.   Current Alzheimer Research

Human Tau Isoforms Assemble into Ribbon-like Fibrils That Display Polymorphic Structure and Stability

(2010) Susanne Wegmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Cross Talk between Misfolded Proteins in Animal Models of Alzheimer's and Prion Diseases

(2010) R. Morales et al.   JOURNAL OF NEUROSCIENCE

A causative link between the structure of aberrant protein oligomers and their toxicity

(2010) Silvia Campioni et al.   Nature Chemical Biology

Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

(2010) Sang-Won Min et al.   NEURON

Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models

(2010) J. van Eersel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Charge interactions can dominate the dimensions of intrinsically disordered proteins

(2010) S. Muller-Spath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Darwinian Evolution of Prions in Cell Culture

(2010) J. Li et al.   SCIENCE

Modulation and Detection of Tau Aggregation with Small-Molecule Ligands

(2009) Edward Chang et al.   Current Alzheimer Research

Switching in amyloid structure within individual fibrils: Implication for strain adaptation, species barrier and strain classification

(2009) Ilia V. Baskakov   FEBS LETTERS

Methods for structural characterization of prefibrillar intermediates and amyloid fibrils

(2009) Annette Eva Langkilde et al.   FEBS LETTERS

Conformational Switching within Individual Amyloid Fibrils

(2009) Natallia Makarava et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Propagation of Tau Misfolding from the Outside to the Inside of a Cell

(2009) Bess Frost et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Accumulation of Aspartic Acid421- and Glutamic Acid391-Cleaved Tau in Neurofibrillary Tangles Correlates With Progression in Alzheimer Disease

(2009) Gustavo Basurto-Islas et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Transmission and spreading of tauopathy in transgenic mouse brain

(2009) Florence Clavaguera et al.   NATURE CELL BIOLOGY

Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies

(2009) Kurt R. Brunden et al.   NATURE REVIEWS DRUG DISCOVERY

Prion-like mechanisms in neurodegenerative diseases

(2009) Bess Frost et al.   NATURE REVIEWS NEUROSCIENCE

The Transcellular Spread of Cytosolic Amyloids, Prions, and Prionoids

(2009) Adriano Aguzzi et al.   NEURON

Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

(2009) Diane P. Hanger et al.   TRENDS IN MOLECULAR MEDICINE

O -GlcNAcylation modulates the self-aggregation ability of the fourth microtubule-binding repeat of tau

(2008) Chun-Hui Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Natively Unfolded Character of Tau and Its Aggregation to Alzheimer-like Paired Helical Filaments†

(2008) Sadasivam Jeganathan et al.   BIOCHEMISTRY

Domain Conformation of Tau Protein Studied by Solution Small-Angle X-ray Scattering†

(2008) Efstratios Mylonas et al.   BIOCHEMISTRY

Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression

(2008) Tadanori Hamano et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models

(2008) V. Corsetti et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Ultrastructural study of florid plaques in variant Creutzfeldt-Jakob disease: a comparison with amyloid plaques in kuru, sporadic Creutzfeldt-Jakob disease and Gerstmann-Sträussler-Scheinker disease

(2008) B. Sikorska et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Complementary dimerization of microtubule-associated tau protein: Implications for microtubule bundling and tau-mediated pathogenesis

(2008) K. J. Rosenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers

(2007) Fernanda G. De Felice et al.   NEUROBIOLOGY OF AGING